Clinical characteristics and epilepsy in genomic imprinting disorders: Angelman syndrome and Prader–Willi syndrome by Tzong-Shi Wang, Wen-Hsin Tsai, Li-Ping Tsai, Shi-Bing Wong

“…For PWS patients, epilepsy is not common and easy to treat. Conversely, AS is a single-gene disorder induced by ubiquitin-protein ligase E3A dysfunction, which only expresses from a maternal allele. …”
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COVID-19-Associated Biventricular Takotsubo Syndrome Complicated with Cardiogenic Shock (Clinical Case) by E. M. Zeltyn-Аbramov, N. I. Belavina, N. N. Klochkova, R. T. Iskhakov, O. Yu. Evsyukov, L. Yu. Аrtyukhina, A. M. Svanadze, M. A. Lysenko

“…The presented case demonstrates a life-threatening TS pattern in patients with severe COVID-19. TPE procedure should be treated as a possible trigger of TS.…”
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The Effects of Caffeine Toxicity on The Liver in WistarRats by Innih, S.O.*, Calmday-Ombo, D.

“…Groups B, C and D were the caffeine intoxicated groups treated with 200, 400, and 800mg/kg body weight of caffeine. …”
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Rectal spacer use and overall long-term healthcare costs: payer perspective by James B. Yu, Ryoko Sato, Michael R. Folkert, Samir Bhattacharyya, Emmanuel Ezekekwu, Daniel A. Hamstra

“…However, total insurer paid costs over the following 4 years post-RT were significantly lower for RS patients by $8,095 ($52,345 vs. $60,440, p=0.011). Similar patterns were observed when examining costs related to bowel, sexual, or urinary dysfunction separately.ConclusionsPatients with RS use undergoing PCa RT had significantly lower long-term overall healthcare costs despite incurring higher initial costs prior to and during RT, suggesting that upfront investment in RS may be offset by long-term savings for insurers.…”
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The Effect of Audible Joint Manipulation Sounds in the Upper Cervical Spine on Brain Wave and Autonomic Nervous System Activity by Dalton Whitman, Rob Sillevis, Matthew Frommelt

“…Background: High-velocity, low-amplitude (HVLA) manipulation is a common manual therapy technique used for treating pain and musculoskeletal dysfunction. An audible manipulation sound is commonly experienced by patients who undergo HVLA manipulation; however, there is little known about the effects and clinical relevance of the audible manipulation sound on cortical output and the autonomic nervous system. …”
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Targeted discovery of gut microbiome-remodeling compounds for the treatment of systemic inflammatory response syndrome by Luyao Liu, Lin Ma, Huan Liu, Fan Zhao, Pu Li, Junhua Zhang, Xin Lü, Xin Zhao, Yanglei Yi

“…ABSTRACT Systemic inflammatory response syndrome (SIRS) is a severe inflammatory response that can lead to organ dysfunction and death. Modulating the gut microbiome is a promising therapeutic approach for managing SIRS. …”
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A Case Report of IgG4-related Disease With Common Clinical Manifestation in an Atypical Gender by Seyed Reza Najafizadeh, Maryam Yaseri

“…Background IgG4-related disease (IgG4-RD) is a recently described clinicopathological condition with a wide range of clinical manifestations including a dense lymphoplasmacytic infiltrate rich in IgG4positive plasma cells, fibrosis arranged in a storiform pattern, obliterative phlebitis, and elevated serum IgG4 concentrations. …”
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Social Media and Men’s Health: Separating Science from Speculation in Andrology by Michael George, Vaibhav Modgil, Ian Pearce, Theodora Stasinou

“…Key men’s health topics such as infertility, erectile dysfunction, testosterone supplementation and semen retention are popular amongst social media posts, amassing millions-to-billions of views depending on the platform. …”
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From hypertension to heart failure: The missed clues of transthyretin cardiac amyloidosis by Ambreen Gul, Kamran Dawood

“…NT-proBNP increased to 1204 ng/L, and cardiac troponin was mildly elevated at 28 ng/L.Electrocardiography (ECG) demonstrated a pseudo-infarct pattern (Fig 1). Repeat echocardiography revealed severe LVH with a restrictive filling pattern, raising suspicion of an infiltrative cardiomyopathy, such as cardiac amyloidosis. …”
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The dual GLP-1 and GIP receptor agonist tirzapetide provides an unintended interaction with the β-adrenoceptors and plays a role in glucose metabolism in hyperglycemic or senescent... by Dunya Aydos, Zeynep Busra Aksoy, Mehmet Altay Unal, Kamil Can Akcali, Ceylan Verda Bitirim, Belma Turan

“…Methods To establish the multifaceted cardioprotective function and underlying mechanisms of TZPD against hyperglycemia (HG)—or senescence (SC)-induced cardiac dysfunction, H9c2 cells were treated with and without TZPD. …”
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NEUROPSYCHIATRIC DISORDERS IN JUVENILE-ONSET SYSTEMIC LUPUS ERYTHEMATOSUS: RESULTS FROM A RETROSPECTIVE STUDY by M. I. Kaleda, I. P. Nikishina, S. I. Glukhova, N. Yu. Stepanenko

“…There was a preponderance of central nervous system lesion (89%) in the pattern of neuropsychiatric manifestations. Fifteen (33.3%) patients had more than one manifestation of neurolupus. …”
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Identification of a metabolic brain network characterizing essential tremor by Solange Volnov, Hamzah Baagil, Oliver Winz, Hans-Juergen Kaiser, Sanne Katherina Meles, Joerg Bernhard Schulz, Kathrin Reetz, Felix Manuel Mottaghy, Florian Holtbernd

“…For network validation and to explore DBS effects, 8 additional ET patients (68.1 ± 8.2 years) treated with DBS were assessed in both the ON and OFF state, respectively. …”
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SURGICAL TECHNIQUE FOR COMPLEX SYNDACTYLY IN APERT SYNDROME: A SERIAL CASE by Williams Mesang, Agus Santoso Budi, Magda Rosalina Hutagalung

“…It is practically symmetrical causing significant dysfunction and infection if not treated properly. The goals in the treatment are the separation of independent digits without disturbing function and growth, the creation of a lined commissure, the provision of skin cover for the denuded nail edge and exposed bone, and to creation of aesthetically pleasing individual fingertips with proper nails, nail folds, and adequate pulp fullness. …”
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A Case of Status Epilepticus in a Patient Experiencing an Acute Attack of Hereditary Angioedema by Danielle Weinberg, Steven Gayda, Kyle Hultz, Hanan Atia, Brian Kohen, Eric Boccio

“…Hereditary angioedema is inherited in an autosomal dominant pattern and results in a quantitative deficiency (HAE type I) or dysfunction (HAE type II) of the C1-esterase inhibitor (C1-INH) protein. …”
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Upper Crossed Syndrome and Scapulae Upper-Trapping: A Mesotherapy Protocol in Cervicoscapulobrachial Pain—The 8:1 Block by Luyddy Pires, Napoliane Santos, João Vitor Lana, Alex Pontes de Macedo, Fábio Ramos Costa, Gabriel Ohana Marques Azzini, Tomas Mosaner, Daniel de Moraes Ferreira Jorge, Gabriel Silva Santos, Arthur Medeiros, José Alexandre Reale Pereira, José Fábio Lana

“…Patients reported significant improvements in pain relief and functional outcomes, underscoring the clinical utility of the 8:1 block in treating cervicoscapulobrachialgia. This protocol offers a feasible, cost-effective intervention that enhances the efficacy of traditional therapeutic exercises by addressing underlying muscular and biomechanical dysfunctions. …”
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Acute necrotizing calculous cholecystitis after treatment with ceftriaxone in an elderly patient: a case report by Tsunehiko Shigemori, Ichiro Imoto, Yasuhiro Inoue, Ryo Nishiwaki, Natsuko Sugimasa, Tetsuya Hamaguchi, Midori Noji, Kenji Takeuchi, Yoshiyuki Ito, Taro Yasuma, Esteban C. Gabazza, Toshio Kato

“…A comparative analysis of the infrared spectroscopic pattern of the composition of gallstones collected during surgery with that of the ceftriaxone powder revealed that both have very similar infrared spectroscopic patterns. …”
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Autoimmune Pulmonary Alveolar Proteinosis: A Rare Diagnosis in Pediatric Age by Inês Pais-Cunha, Augusta Gonçalves, Sara Paulino, José Fontoura Matias, Silva Sónia, Catarina Ferraz, Inês Azevedo

“…Spirometry indicated a mild restrictive pattern (forced vital capacity [FVC] = 77%) and diffusing capacity of the lungs for carbon monoxide (DLCO) showed a moderate decrease at 48.6%. …”
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<i>Exophiala</i> Bloodstream Infections in Humans—A Narrative Review by Afroditi Ziogou, Alexios Giannakodimos, Ilias Giannakodimos, Stella Baliou, Andreas G. Tsantes, Petros Ioannou

“…Fever represented the most frequent clinical presentation (50%), followed by organ dysfunction (21.9%). The yeast generally demonstrated susceptibility to voriconazole and itraconazole. …”
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The impact of armed conflict on maternal morbidity and mortality at a teaching hospital in the Tigray region of Ethiopia: a pre-war and wartime comparative analysis by Hale Teka, Mohamedawel Mohamedniguss Ebrahim, Rahel Nardos, Awol Yemane Legesse, Yibrah Berhe, Haileselassie Berhe, Mulugeta Gebregziabher, Gebre-Egziabher Kiros

“…Key indicators of severe maternal outcomes and patterns of organ dysfunction and critical interventions were examined. …”
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THE INFLAMMASOME DRIVES MICROVASCULAR IMPAIRMENT IN MOUSE MODELS OF INTRAVASCULAR HEMOLYSIS by PL Brito, EMFG Azevedo, LFS Gushiken, FC Leonardo, FF Costa, N Conran

“…Moreover, NLRP3 inflammasome inhibition reduced leukocyte recruitment to the venule walls of HEM mice, indicating an improvement in hemolysis-induced microvascular dysfunction. This was further corroborated by LDF, which showed improved blood perfusion in the skin of MCC950-treated HEM mice. …”
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