Wearable peripheral nerve stimulator reduces essential tremor symptoms through targeted brain modulation by Cuong P. Luu, Jordan Ranum, Youngwon Youn, Jennifer L. Perrault, Bryan M. Krause, Matthew I. Banks, Laura Buyan-Dent, Kip A. Ludwig, Wendell B. Lake, Aaron J. Suminski

“…Recently, transcutaneous afferent patterned stimulation (TAPS), applied through a wrist-worn device, has emerged as a non-invasive treatment for medication-refractory ET. …”
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Effects of intravenous immunoglobulin on the negatively transformed subpopulations of neutrophilic granulocytes in newborns with congenital pneumonia and neonatal sepsis by I. V. Nesterova, S. V. Kovaleva, G. A. Chudilova, L. V. Lomtatidze, T. V. Smerchinskaya, V. N. Chapurina

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Enhancing quality of life through physical exercise in a patient with triple lumbar disc herniation: A longitudinal case study by Kristina Randow de Almeida, Marko Kapeleti, Vuk Stevanović, Vladimir Mrdaković, Marija Macura

“…It alters functional movement patterns and causes improper compensatory body positioning, leading to muscle dysfunction. …”
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Estudio comparativo de las funciones ejecutivas entre pacientes con enfermedad de Parkinson y pacientes con enfermedad degenerativa cerebelosa Comparison study of executive functio... by Carlos G. Abel, Gustavo Stein, Silvia Pereyra, Gabriela Ñano, Tomoko Arakaki, Nélida Garretto, Carlos Mangone, Osvaldo Genovese, Roberto E.P. Sica

“…On the other hand the PD group showed a selective increase of non perseverative errors, without reaching significant between group difference. CONCLUSION: The CD group appears to have greater deficits in EF with a pattern of prefrontal dysfunction.…”
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Interstitial fluid transport in linea alba is involved in acupuncture-induced attenuation of ovarian hypofunction in aged rats by Yaoyao Zhu, Ge Lu, Weixin Li, Chenchen Su, Pengfei Du, Shuyou Wang, Li Yang, Huanfang Xu, Yigong Fang, Xiaojing Song

“…Our study not only provides a mechanistic basis for the clinical efficacy of acupuncture in treating ovarian disorders but also identifies ISF dynamics as a novel therapeutic target in age-related ovarian dysfunction.…”
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Health status and disability in persons with spinal cord injuries in South Africa and Kenya by Conran Joseph, Brenda Lijodi, Adnil Titus, Lucian Bezuidenhout

“…Results: In both countries, sexual dysfunction (55% – 57%), pain (48% – 49%), spasticity (41% – 42%) and bladder dysfunction (27% – 60%) emerged as the predominant secondary medical complications, with sexual dysfunction and pain showing overlap. …”
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Impairment of neuronal activity in the dorsolateral prefrontal cortex occurs early in parkinsonism by Noah Hjelle, Biswaranjan Mohanty, Tanner Hubbard, Matthew D. Johnson, Jing Wang, Luke A. Johnson, Jerrold L. Vitek

“…Little is known, however, regarding how neuronal activity in the executive control network of the brain changes in the parkinsonian condition.ObjectiveInvestigate the impact of parkinsonism on neuronal activity in the dorsolateral prefrontal cortex (DLPFC), a key region in executive control, during a go/nogo reaching task.MethodsUsing a within-subject design, single and multi-unit neuronal activity was recorded in the DLPFC of a nonhuman primate (n = 1) before and after the induction of mild parkinsonism using the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).ResultsCoincident with development of mild parkinsonian motor signs, there was a marked reduction in the percentage of DLPFC cells with significant task-related firing rate modulation during go and nogo conditions.ConclusionThese results suggest that DLPFC dysfunction may occur early in parkinsonism and contribute to cognitive impairments and disrupted executive function often observed in PD patients.…”
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Clinical outcomes of the tunica albuginea plication for patients with Peyronie’s disease: a bicentric retrospective analysis by Pavel Navratil, Jiri Chalupnik, Minh Nguyet Tranova, Miroslav Louda, Pavel Kriz, Pavel Navratil

“…Patients with complex curvature patterns had a higher risk of reoperation. Conclusions Plication surgery is an effective and safe option for treating penile curvature in Peyronie’s disease, particularly in patients with more severe deformities. …”
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Inhibition of the TLR4/RAGE pathway by clearance of extracellular HMGB1 is a potential therapeutic target for radiation-damaged salivary glands by Takashi I, Riho Kanai, Makoto Seki, Hideki Agata, Hideaki Kagami, Hiroshi Murata, Izumi Asahina, Simon D. Tran, Yoshinori Sumita

“…Additionally, culture supernatant of irradiated cultured SG epithelial cells contained damaged associated molecular pattern (DAMP)/senescence-associated secretory phenotype (SASP) factors. …”
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Budesonide promotes airway epithelial barrier integrity following double-stranded RNA challenge. by Clara Rimmer, Savas Hetelekides, Sophia I Eliseeva, Steve N Georas, Janelle M Veazey

“…Respiratory viruses are responsible for a large fraction of asthma exacerbations, and are particularly potent at disrupting epithelial barrier function through pattern recognition receptor engagement leading to tight junction dysfunction. …”
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Atrioventricular Conduction Abnormalities in Multisystem Inflammatory Syndrome in Children by Carlos A. Carmona, Fatma Levent, Kelvin Lee, Bhavya Trivedi

“…Cardiac manifestations in multisystem inflammatory syndrome in children (MIS-C) can include coronary artery aneurysms, left ventricular systolic dysfunction, and electrocardiographic disturbances. …”
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Clinical manifestations, histopathological changes and quality of life in patients with advanced knee osteoarthritis caused by age, trauma, obesity and their combination by Kristina V. Korochina, Tatyana V. Chernysheva, Irina E. Korochina

“…The methodological basis for differential approach to treating different categories of OA patients was developed.…”
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Transvertebral magnetic neuromodulation for the treatment of overactive bladder: 6 months follow-up by G V. Kovalev, D. D. Shkarupa, N. D. Kubin, A. O. Zaitseva, I. V. Borodulina, P. E. Musienko

“…The most common type of lower urinary tract dysfunction is an overactive bladder (OAB). Today there is a need to search for new effective methods of treating this disease.Purpose of the study. …”
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Disseminated intravascular coagulation by Satoshi Gando, Marcel Levi, Cheng-Hock Toh

“…Conversely, these pathogenic pathways and DIC synergistically contribute to organ dysfunction, leading to poor prognoses. Effective DIC management requires treating the underlying condition, along with substitution therapies and, in some cases, antifibrinolytics. …”
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Acupuncture treatment for functional gastrointestinal disorders: Identification of major acupoints using network analysis by Heeyoung Moon, Yeonhee Ryu, In-Seon Lee, Younbyoung Chae

“…These findings could be applied in future acupuncture research on therapy for gastrointestinal system dysfunction. They may also help bridge the gap between the traditional meridian theory, which assumes that there is a link between diseases/symptoms and the specific body region being treated, and real-world clinical evidence.…”
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Agomelatine: A review for general practitioners by K. Outhoff

“…Agomelatine is a melatonin 1 (MT1) and melatonin 2 (MT2) receptor agonist and serotonin (5-hydroxytryptamine) 2C (5-HT2C) receptor antagonist. It is effective in treating moderate-to-severe depression, alleviating the symptoms of anxiety, and restoring the disrupted sleep patterns that often result from this potentially devastating disease. …”
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Lactylation-related gene signature accurately predicts prognosis and immunotherapy response in gastric cancer by Xuezeng Sun, Haifeng Dong, Rishun Su, Jingyao Chen, Wenchao Li, Songcheng Yin, Changhua Zhang

“…The group with lower risk showed increased Tumor Immune Dysfunction and Exclusion (TIDE) score and greater responsiveness to immunotherapy. …”
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A Case Report on the Thyroid and Eye Connection: A Deep Dive into Evaluation and Treatment Strategies by Iqra Mushtaq, Kalibo Jakhalu, Tushar Agrawal, Gufran Ali Kamdar

“…Among individuals diagnosed with TAO, about 90% have Graves’ hyperthyroidism, while a smaller percentage may have primary hypothyroidism, Hashimoto’s thyroiditis, or normal thyroid function. These patterns emphasise the importance of recognising thyroid dysfunction in orbitopathy management which includes treating the underlying thyroid dysfunction, using corticosteroids to reduce inflammation, and applying artificial tears for symptomatic relief. …”
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Fever as a Catalyst for Life‐Threatening Arrhythmias in Brugada Syndrome: A Rare Case of Brugada Syndrome Unmasked in a Young Male by Ibrahim Khalil, Md. Imran Hossain

“…His temperature was recorded at 39°C, and a 12‐lead ECG revealed a Type 1 Brugada pattern, confirming a fever‐triggered BrS diagnosis. …”
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Resistant Hypertension and Obstructive Sleep Apnea by Akram Khan, Nimesh K. Patel, Daniel J. O’Hearn, Supriya Khan

“…The mechanism proposed is a pattern of intermittent hypoxia associated with hyperaldosteronism, increased sympathetic tone, endothelial dysfunction, and inflammation. …”
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