National Trends in Medication Prescriptions for Male Lower Urinary Tract Symptoms and Erectile Dysfunction: Findings from the Norwegian Prescription Database by Patrick Juliebø-Jones, Ingunn Roth, Christian Arvei Moen, Peder Gjengstø, Christian Beisland

“…Patient summary: In Norway, there were increasing trends in the use of medications to treat benign prostate enlargement (BPE), erectile dysfunction, and urinary incontinence between 2004 and 2020. …”
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Expression of matrix metalloproteinases 1, 2, 9, 12 in xenogenic tissues of epoxy-crosslinked bioprosthetic heart valves explanted due to dysfunction by A. E. Kostyunin, T. V. Glushkova

“…To study the expression patterns of matrix metalloproteinases (MMPs) -1, -2, -9, -12 in the leaflets of the epoxy-treated bioprostheses explanted due to dysfunction and to identify the pathways for the accumulation of these enzymes in the xenogenic tissues.Methods. 19 leaflets from seven epoxy-treated bioprostheses (Kemcor (n = 2), PeriCor (n = 2), UniLine (n = 2) and TiAra (n = 1)) explanted from the mitral or aortic positions during repeat heart valve replacements were included in a study. …”
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Interactions between Endoplasmic Reticulum Stress and Autophagy: Implications for Apoptosis and Neuroplasticity-Related Proteins in Palmitic Acid-Treated Prefrontal Cells by Xiangli Xue, Feng Li, Ming Cai, Jingyun Hu, Qian Wang, Shujie Lou

“…The present study illustrated that both ER stress and autophagy could be involved in apoptosis and decreased neuroplasticity-related proteins, and the interaction between ER stress and autophagy may play a critical role in apoptosis in PA-treated prefrontal cells. Our results provide new insights into the molecular mechanisms in vitro of lipotoxicity in obesity-related cognitive dysfunction.…”
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The role of irregular eating behaviors in metabolic dysfunction-associated steatotic liver disease: evidence from a multicenter cross-sectional study in China by Xingxing Ren, Miao Zhang, Xiaoyang Sun, Lili Zheng, Yufang Bi, Qiang Li, Lirong Sun, Fusheng Di, Yushan Xu, Dalong Zhu, Yanyan Gao, Yuqian Bao, Yao Wang, Lanjie He, Xin Gao, Jian Gao, Mingfeng Xia, Hua Bian

“…Abstract Background Irregular eating patterns, such as skipping breakfast and late dinner consumption, have been linked to adverse metabolic profiles. …”
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The adverse effects of metabolic disorder on left ventricular myocardial mechano-energetic efficiency and dysfunction in ischemic cardiomyopathy: insight from a cardiac MRI study by Li Jiang, Yuan Li, Xue-Ming Li, Ke Shi, Han Fang, Wei‑Feng Yan, Ying‑Kun Guo, Hua‑Yan Xu, Zhi-Gang Yang

“…Conclusions Our results revealed whether coexisting any MetF, rather than coexisting a greater number of MetF, is associated with the reduction of LV myocardial mechano-energetic efficiency and dysfunction in patients with ICM, suggesting that clinicians should promptly identify and treat any coexisting MetF in the management of ICM patients. …”
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Inflammatory signaling pathways in pancreatic β-cell: New insights into type 2 diabetes pathogenesis by Jie Chen, Shinuan Fei, Lawrence W.C. Chan, Xueting Gan, Bibo Shao, Hong Jiang, Sheng Li, Peng Kuang, Xin Liu, Sijun Yang

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Epidemiological trends and burden of metabolic dysfunction-associated steatotic liver disease in the Middle East and North Africa region: a 32-year analysis of health impact by Zahra Sarkoohi, Mohammad-Mahdi Bastan, Mohammad Amin Khajuei Gharaei, Mahsa Iranmanesh, Arya Adinepour, Reyhane Khajezade, Faegheh Bahri, Fatemeh Akhlaghi, Azin Kadkhodamanesh, Hossein Pourghadamyari, Hamid Sharifi, Omid Eslami, Seyed Aria Nejadghaderi

“…Abstract Background Metabolic dysfunction-associated steatotic liver disease (MASLD) is a condition marked by excess liver fat, ranging from simple steatosis to non-alcoholic steatohepatitis. …”
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Histological profiling of the extracellular matrix of streptozotocin-induced diabetic nephropathy in experimental mice and rats, an analytical study by Anas K. Al Makhzoomi

“…Diabetic nephropathy (DN) is characterized by dysfunction and a complication of the extracellular matrix (ECM) with an abnormal pattern of Glycosaminoglycan (GAG) synthesis. …”
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Radiological Healing Patterns and Functional Outcomes After Conservative Treatment of Unilateral Condylar Fractures: A Report of Two Cases by Edoardo Staderini, Irene Cavalcanti, Anna Schiavelli, Patrizia Gallenzi, Gabriele Di Carlo, Massimo Cordaro

“…(1) <b>Background:</b> Condylar fracture healing pattern classification in children and adolescents is primarily based on the radiological assessment of condylar morphology; however, recent studies showed the presence of a poor correlation between post-treatment radiological findings and clinical temporomandibular joint (TMJ) dysfunction. …”
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Comparison of sepsis-associated acute kidney injury with different degrees and causes reveals patterns in mitochondrial metabolism and immune infiltration changes by Nan Yuan, Jianwen Chen, Feng Luo, Zhenyu Fang, Mengjie Huang, Jiaona Liu, Xiangmei Chen, Congjuan Luo

“…It remains primarily treated with supportive and nonspecific therapies because of the absence of effective diagnostic biomarkers and therapeutic targets. …”
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Traumatic degloving injuries: a prospective study to assess injury patterns, management, and outcomes at a single center in northern India by Divij Jayant, Atul Parashar, Ramesh Sharma

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Morbid Jealousy in Alcohol Dependence: A Cross-sectional Study in Hospital-admitted Patients at a Rural Tertiary Health Center by Harshal Shriram Sathe, Akanksha Nagnath Tamshete, Nitisha Pramod Shirbhate, Gaurav Pawar

“…This study aims to explore the determinants of MJ in patients with alcohol dependence syndrome (ADS), focusing on its correlation with sociodemographic variables, drinking patterns and severity, sexual dysfunction, and couple satisfaction. …”
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Pulmonary hypertension associated with neurofibromatosis type 2 by Hirohisa Taniguchi, Tomoya Takashima, Ly Tu, Raphaël Thuillet, Asuka Furukawa, Yoshiko Furukawa, Akio Kawamura, Marc Humbert, Christophe Guignabert, Yuichi Tamura

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Retrospective Analysis of Healthcare Resource Use, Treatment Patterns, and Treatment-related Events in Patients with Huntington’s Disease–associated Chorea Initiated on Tetrabenazi... by Victor W. Sung, Sanjay K. Gandhi, Victor Abler, Brian Davis, Debra E. Irwin, Karen E. Anderson, Ravi G. Iyer

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Divergent psychological stress response patterns to the COVID-19 pandemic in psychiatric patients with vs. without PTSD: A real-world exploratory study. by Marit Treptow, Claudia Bartels, Mirjana Ruhleder, Alexander Kratzenberg, Thorgund Reh-Bergen, Mona Abdel-Hamid, Luisa Heß, Jörg Signerski-Krieger, Katrin Radenbach, Björn-Hendrik Schott, Jens Wiltfang, Claus Wolff-Menzler, Ulrike Schmidt, Michael Belz

“…In particular, it remains unclear which pandemic-related stress response pattern occurs in pre-existing posttraumatic stress disorder (PTSD) during the pandemic - at the same time these patients potentially exhibit dysfunctional coping of artificially generated psychosocial stressors. …”
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Four secondary malignancies, coronary artery disease, aortic atherosclerosis and severe constrictive pericarditis in a survivor of hodgkin lymphoma treated with radiation therapy:... by A. Jeri-Yabar, J. Garazatua-Gonzalez, W. Montoya-Rivera, V. Ortuzar-Seminario, C. Lozada Zingoni, V. Massuco

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Clinical characteristics and a changing trend of antimicrobial susceptibility pattern of Streptococcus suis infection at Siriraj Hospital: a 16-year retrospective study by Dr Anupop Jitmuang, Dr Chittamas Panpaeng, Dr Wichuda Kamolvit

“…Thus, the study aims to delineate the clinical characteristics and treatment outcomes and to explore the changing pattern of the antimicrobial susceptibility (AST) of S. suis infection in humans. …”
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Effects of antagonistic network-targeted tDCS on brain co-activation patterns depends on the networks’ electric field: a simultaneous tDCS-fMRI study by Hechun Li, Hongru Shi, Sisi Jiang, Changyue Hou, Haonan Pei, Hanxi Wu, María Luisa Bringas Vega, Gang Yao, Dezhong Yao, Cheng Luo

“…Six recurring brain patterns (co-activation patterns, CAPs) were identified. …”
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Purinergic receptor antagonism reduces interictal discharges and rescues cognitive function in a mouse model of temporal lobe epilepsy by Nelson Espinosa, Soraya Martín-Suárez, Ariel Lara-Vasquez, Trinidad Montero, Teresa Muro-García, German Fernandez, Juan Manuel Encinas-Pérez, Juan Manuel Encinas-Pérez, Juan Manuel Encinas-Pérez, Pablo Fuentealba

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Oral administration of butylated hydroxytoluene induces neuroprotection in a streptozotocin-induced rat Alzheimer’s disease model via inhibition of neuronal ferroptosis by Parisa Faraji, Elham Parandavar, Hartmut Kuhn, Mehran Habibi-Rezaei, Astrid Borchert, Elham Zahedi, Shahin Ahmadian

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