Fever as a Catalyst for Life‐Threatening Arrhythmias in Brugada Syndrome: A Rare Case of Brugada Syndrome Unmasked in a Young Male by Ibrahim Khalil, Md. Imran Hossain

“…Fever is a recognized trigger that can unmask the Type 1 Brugada electrocardiogram (ECG) pattern and precipitate life‐threatening arrhythmias, even in individuals without prior cardiac symptoms. …”
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Social-demographic factors and nursing diagnosis in patients with kidney transplant by Ana Luisa Brandão de Carvalho Lira, Marcos Venícios de Oliveira Lopes, Lúcia de Fátima da Silva, Thelma Leite de Araujo

“…Ten diagnosis presented frequency above the 75th percentile: risk of Infection; disturbed sensory perception; visual; hearing; Sleep pattern disturbance; Imbalanced nutrition; fatigue; sexual dysfunction; disturbed sensory perception: acute pain, more than body requirements; The nursing diagnosis study contributes to increasing the knowledge of realty of these patients, which is a necessary step for the establishment of nursing assistance to the renal transplanted, as well as for the direction of outcomes to be reached aiming the improvement of life quality.  …”
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Lactylation-related gene signature accurately predicts prognosis and immunotherapy response in gastric cancer by Xuezeng Sun, Haifeng Dong, Rishun Su, Jingyao Chen, Wenchao Li, Songcheng Yin, Changhua Zhang

“…Lactylation of proteins is detected in gastric cancer tumors and is linked to the advancement of gastric cancer.MethodsThe The Cancer Genome Atlas (TCGA) was utilized to analyze the gene expression levels associated with lactylation. A genetic pattern linked to lactylation was created using Univariate Cox regression and least absolute shrinkage and selection operator (LASSO) regression. …”
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Multiple kernel learning captures a systems-level functional connectivity biomarker signature in amyotrophic lateral sclerosis. by Tomer Fekete, Neta Zach, Lilianne R Mujica-Parodi, Martin R Turner

“…Intra- as well as inter-motor functional networks in the 0.03-0.06 Hz frequency band were derived from 40 patients and 30 healthy controls of similar age, and used as features for pattern detection, employing multiple kernel learning. …”
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Resistant Hypertension and Obstructive Sleep Apnea by Akram Khan, Nimesh K. Patel, Daniel J. O’Hearn, Supriya Khan

“…The mechanism proposed is a pattern of intermittent hypoxia associated with hyperaldosteronism, increased sympathetic tone, endothelial dysfunction, and inflammation. …”
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Acute necrotizing calculous cholecystitis after treatment with ceftriaxone in an elderly patient: a case report by Tsunehiko Shigemori, Ichiro Imoto, Yasuhiro Inoue, Ryo Nishiwaki, Natsuko Sugimasa, Tetsuya Hamaguchi, Midori Noji, Kenji Takeuchi, Yoshiyuki Ito, Taro Yasuma, Esteban C. Gabazza, Toshio Kato

“…A comparative analysis of the infrared spectroscopic pattern of the composition of gallstones collected during surgery with that of the ceftriaxone powder revealed that both have very similar infrared spectroscopic patterns. …”
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Investigating intra‐tumoural heterogeneity and microenvironment diversity in primary cardiac angiosarcoma through single‐cell RNA sequencing by Jingyuan Huo, Zhen Wang, Wenting Zhao, Miao Chen, Haoyang Li, Fengpu He, Xiao Tian, Yaqi Ma, Firyuza Husanova, Liang Ma, Yiming Ni, Hongda Ding, Weidong Li, Hongfei Xu

“…Key points Insights into the heterogeneity and transcriptional patterns of sarcoma cells may explain the challenges in treating primary cardiac angiosarcoma (PCAS) using the current therapeutic modalities. …”
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Ventricular volume adjustment of brain regions depicts brain changes associated with HIV infection and aging better than intracranial volume adjustment by Benedictor Alexander Nguchu, Benedictor Alexander Nguchu, Jing Zhao, Jiajun Fan, Yifei Han, Yu Lu, Han Jin, Yanming Wang, Hongjun Li, Peter Shaw

“…The analyses of LV-adjusted metrics also show that atrophic patterns observed in the hippocampus, thalamus and pallidum were strongly correlated with HAND(especially dysfunction in executive function) and clinical markers (i.e., CD4/CD8 ratio).ConclusionWe conclude that models that control for individual variability in intracranial and ventricular volumes have the potential to minimize discrepancies and variations in structural reports of HIV, improving the diagnostic power of identified patterns and fostering greater consistency across research studies. …”
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Clinical characteristics and epilepsy in genomic imprinting disorders: Angelman syndrome and Prader–Willi syndrome by Tzong-Shi Wang, Wen-Hsin Tsai, Li-Ping Tsai, Shi-Bing Wong

“…For PWS patients, epilepsy is not common and easy to treat. Conversely, AS is a single-gene disorder induced by ubiquitin-protein ligase E3A dysfunction, which only expresses from a maternal allele. …”
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Enhanced beta power emerges from simulated parkinsonian primary motor cortex by Donald W. Doherty, Liqiang Chen, Yoland Smith, Thomas Wichmann, Hong-Yuan Chu, William W. Lytton

“…Dysfunction in PT5B neurons, the final-common-pathway to brainstem and spinal cord, provides a new target to treat PD motor symptoms.…”
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COVID-19-Associated Biventricular Takotsubo Syndrome Complicated with Cardiogenic Shock (Clinical Case) by E. M. Zeltyn-Аbramov, N. I. Belavina, N. N. Klochkova, R. T. Iskhakov, O. Yu. Evsyukov, L. Yu. Аrtyukhina, A. M. Svanadze, M. A. Lysenko

“…The presented case demonstrates a life-threatening TS pattern in patients with severe COVID-19. TPE procedure should be treated as a possible trigger of TS.…”
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THE INFLAMMASOME DRIVES MICROVASCULAR IMPAIRMENT IN MOUSE MODELS OF INTRAVASCULAR HEMOLYSIS by PL Brito, EMFG Azevedo, LFS Gushiken, FC Leonardo, FF Costa, N Conran

“…Moreover, NLRP3 inflammasome inhibition reduced leukocyte recruitment to the venule walls of HEM mice, indicating an improvement in hemolysis-induced microvascular dysfunction. This was further corroborated by LDF, which showed improved blood perfusion in the skin of MCC950-treated HEM mice. …”
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The Effects of Caffeine Toxicity on The Liver in WistarRats by Innih, S.O.*, Calmday-Ombo, D.

“…The data obtained from this study suggests that Caffeine induces hepatotoxicity in ascending manner of dose- dependent pattern in adult Wistar rats.…”
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A Case Report of IgG4-related Disease With Common Clinical Manifestation in an Atypical Gender by Seyed Reza Najafizadeh, Maryam Yaseri

“…Background IgG4-related disease (IgG4-RD) is a recently described clinicopathological condition with a wide range of clinical manifestations including a dense lymphoplasmacytic infiltrate rich in IgG4positive plasma cells, fibrosis arranged in a storiform pattern, obliterative phlebitis, and elevated serum IgG4 concentrations. …”
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The prevalence and correlates of low sexual functioning in women on hemodialysis: A multinational, cross-sectional study. by Valeria Saglimbene, Patrizia Natale, Suetonia Palmer, Marco Scardapane, Jonathan C Craig, Marinella Ruospo, Letizia Gargano, Giuseppe Lucisano, Marietta Török, Eduardo Celia, Rubén Gelfman, Anna Bednarek-Skublewska, Jan Dulawa, Paul Stroumza, Miguel Leal, Domingo Del Castillo, Angelo Marco Murgo, Staffan Schon, Charlotta Wollheim, Jörgen Hegbrant, Giovanni F M Strippoli

“…The aim of this study was to assess prevalence and correlates of the individual domains of sexual functioning in women treated with hemodialysis. We recruited, into this multinational cross-sectional study, women treated with long-term hemodialysis (Collaborative Working Group on Depression and Sexual dysfunction in Hemodialysis study). …”
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From hypertension to heart failure: The missed clues of transthyretin cardiac amyloidosis by Ambreen Gul, Kamran Dawood

“…NT-proBNP increased to 1204 ng/L, and cardiac troponin was mildly elevated at 28 ng/L.Electrocardiography (ECG) demonstrated a pseudo-infarct pattern (Fig 1). Repeat echocardiography revealed severe LVH with a restrictive filling pattern, raising suspicion of an infiltrative cardiomyopathy, such as cardiac amyloidosis. …”
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Social Media and Men’s Health: Separating Science from Speculation in Andrology by Michael George, Vaibhav Modgil, Ian Pearce, Theodora Stasinou

“…Social media algorithms reinforce consumption patterns by continuously delivering content based on user engagement: the more an individual interacts with a topic or creator, the more related content appears, creating a self-sustaining feedback loop; this principle underpins the concept of virality and risks the rapid dissemination of inaccuracies online. …”
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Sexual Motivation (Desire): Problems with Current Preclinical and Clinical Evaluations of Treatment Effects and a Solution by Anders Ågmo

“…There has been an extensive search for efficient pharmacological treatment of female sexual interest/arousal disorder and other sexual dysfunctions. However, available treatments have met limited success, except for the drugs used for treating erectile deficiency. …”
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Clinical, pathogenetic and prognostic value of diabetic retinopathy’s progression after phacoemulsification in patients with the essential hypertension by N. S. Khodjaev, V. V. Chernikh, K. E. Kuntysheva

“…All identified laboratory patterns were confirmed by the parallel dynamic prospective ophthalmic studies that demonstrated a higher incidence of vascular disorders after phacoemulsification in patients with diabetic retinopathy and hypertension who were not taking ACE inhibitors. …”
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The dual GLP-1 and GIP receptor agonist tirzapetide provides an unintended interaction with the β-adrenoceptors and plays a role in glucose metabolism in hyperglycemic or senescent... by Dunya Aydos, Zeynep Busra Aksoy, Mehmet Altay Unal, Kamil Can Akcali, Ceylan Verda Bitirim, Belma Turan

“…Methods To establish the multifaceted cardioprotective function and underlying mechanisms of TZPD against hyperglycemia (HG)—or senescence (SC)-induced cardiac dysfunction, H9c2 cells were treated with and without TZPD. …”
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