Prognostic Value of Epicardial Adipose Tissue in Heart Failure With Mid‐Range and Preserved Ejection Fraction: A Multicenter Study by Wenxian Wang, Yan Gao, Jian Wang, Congshan Ji, Hui Gu, Xianshun Yuan, Shifeng Yang, Ximing Wang

“…Background Epicardial adipose tissue (EAT) accumulation is thought to play a role in the pathophysiology of heart failure (HF) with mid‐range ejection fraction and HF with preserved ejection fraction, but its effect on outcome is unknown. …”
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Mid-Range Inhomogeneity of Eukaryotic Genomes by Larisa Fedorova, Alexei Fedorov

“…These regions are associated with unusual DNA conformations and/or particular DNA properties. In particular, mid-range inhomogeneous regions have complex arrangements relative to each other and to specific genomic sites, such as centromeres, telomeres, and promoters, pointing to their important role in genomic functioning and organization.…”
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Impact of obesity on echocardiographic parameters and N-terminal pro-brain natriuretic peptide levels in patients with heart failure with mid-range ejection fraction: unanswered qu... by E. A. Lyasnikova, A. A. Kuular, A. V. Pavlovskaya, A. N. Vlasenko, A. V. Kozlenok, A. Yu. Babenko, M. Yu. Sitnikova, E. V. Shlyakhto

“…To analyze and compare the clinical, echocardiographic characteristics and serum N-terminal pro-brain natriuretic peptide (NT-proBNP) levels depending on the central cardiometabolic risk factors, with a focus on obesity, in patients with heart failure (HF) with mid-range ejection fraction (HFmrEF).Material and methods. …”
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Angiotensin receptor neprilysin inhibition versus individualized RAAS blockade: design and rationale of the PARALLAX trial by Rolf Wachter, Sanjiv J. Shah, Martin R. Cowie, Peter Szecsödy, Victor Shi, Ghionul Ibram, Ziqiang Zhao, Jianjian Gong, Sven Klebs, Burkert Pieske

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Pharmacoepidemiological analysis of routine management of heart failure patients in the Russian Federation. Part I by Yu. M. Lopatin, S. V. Nedogoda, M. V. Arkhipov, A. S. Galyavich, N. A. Koziolova, N. G. Lozhkina, E. V. Reznik, A. S. Salasyuk, M. Yu. Frolov, A. I. Chesnikova, E. V. Chumachek, L. A. Shpagina

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Myocardial mechanical function measured by cardiovascular magnetic resonance in patients with heart failure by Yufan Gao, Boxin Li, Yanhe Ma, Shuo Liang, Anhong Yu, Hong Zhang, Zhigang Guo

“…The HF patients were further categorized as HF with preserved ejection fraction (HFpEF, n = 80), with mid-range ejection fraction (HFmrEF, n = 34), and with reduced ejection fraction (HFrEF, n = 81). …”
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Correlation between mitral annular plane systolic excursion (MAPSE) at different degrees of ejection fraction in patients with diabetes mellitus by Muhammad Rido, Khalid Saleh, A. Makbul Aman, Syakib Bakri, Haerani Rasyid, Andi Alfian Zainuddin

“…No significant results were observed in subjects with mid-range EF. Conclusions. This research revealed that mitral annular plane systolic excursion (MAPSE) is significantly associated with ejection fraction (EF) in individuals with diabetes mellitus (DM), mainly when EF is either well-maintained or diminished.…”
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Efficacy of angiotensin receptor neprilysin inhibitor for maintenance hemodialysis patients with different types of left ventricular ejection fraction heart failure by Jin-cong Li, Nan-hui Zhang, Lei Wang, Jun-meng Peng, Hui-hui Wang, Wen-hui Chen

“…According to the level of LVEF, they were assigned into three groups of HF with reduced ejection fraction（HFrEF, n=41）, HF with mid-range ejection fraction（HFmrEF, n=42） and HF with preserved ejection fraction（HFmrEF, n=2）. …”
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The effect of empagliflozin on the development of chronic heart failure after myocardial infarction according to a 12-month prospective study by Alexey A. Nekrasov, Elena S. Timoschenko, Leonid G. Strongin, Tatyana A. Nekrasova, Anastasiya A. Baranova, Svetlana N. Botova, Michail V. Timoschenko, Mariya A. Yaroslavtseva

“…This effect may be based on the ability of empagliflozin to improve the state of the heart including the delay of postinfarction remodeling, the improvement of pulmonary artery hemodynamics, systolic and diastolic function, the reduction of risk of chronic HF with reduced and mid-range ejection fraction.…”
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Differential Effects of Landiolol in Patients with Atrial Fibrillation and Atrial Tachycardia by Kengo Ayabe, Tomoyoshi Komiyama, Hiroyuki Takekawa, Honsa Kang, Yasuaki Tsumagari, Miwa Ito, Keiichi Ashikaga, Yoshisato Shibata

“…We found that while landiolol was effective in managing patients with AF and heart failure with a preserved or mid-range ejection fraction, however, it might be more challenging to control heart rate in patients with AT using a similar dosage of landiolol.…”
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ROLE OF GENDER SPECIFICS IN MYOCARDIAL REMODELLING, CARDIOVASCULAR COMPLICATIONS DEVELOPMENT AND EFFICACY OF PHARMACOTHERAPY IN HEART FAILURE PATIENTS AFTER CARDIAC SURGERY by Yu. V. Liskova, А. А. Stadnikov, S. P. Salikova

“…The relations were studied, of post-surgery complications with EchoCG data and morphological changes in LAA myocardium, taken the gender and left ventricle ejection fraction (LVEF).Results. In cardiac surgery group with heart failure and preserved LVEF (HFpEF) with the increase of CHF functional class, normal LVEF remained, and there was worsening of the LV diastolic function. …”
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CLINICAL VALUE OF BLOOD BIOMARKERS IN PATIENTS WITH CHRONIC HEART FAILURE by A. M. Aliyeva, E. V. Reznik, E. T. Hasanova, I. V. Zhbanov, I. G. Nikitin

“…The European Society of Cardiology recommends the determination of blood NP level in suspicion of HF and its use as one of the mandatory diagnostic criteria for CHF with preserved and mid-range ejection fraction. Dynamics of NP concentration may be predictor of the effectiveness of the therapy and the necessity of the titration of the dose of HF drugs. …”
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Chronic Heart Failure in Patients with Arterial Hypertension Associated with Obstructive Sleep Apnea Syndrome: Possible Options to Pathogenetic Therapy by A. V. Yakovlev, S. N. Shilov, E. N. Berezikova, N. F. Yakovleva, A. T. Teplyakov, E. V. Grakova, K. V. Kopeva, I. A. Efremov

“…To study approaches to the treatment of chronic heart failure (CHF) with reduced and mid-range left ventricular ejection fraction (LVEF) in patients with arterial hypertension (AH) against the background of obstructive sleep apnea (OSA).Material and methods. …”
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