Hypoxia induces an immunodominant target of tuberculosis specific T cells absent from common BCG vaccines. by Hannah Priyadarshini Gideon, Katalin Andrea Wilkinson, Tige R Rustad, Tolu Oni, Heinner Guio, Robert Andrew Kozak, David R Sherman, Graeme Meintjes, Marcel A Behr, Hans Martin Vordermeier, Douglas Brownlee Young, Robert John Wilkinson

“…In addition, the IL-2 response to Rv1986 was significantly lower in HIV-TB co-infected persons than in HIV uninfected persons, and significantly increased during antiretroviral therapy. These findings demonstrate that Rv1986 is an immunodominant target of memory T cells and is therefore of relevance when considering the partial efficacy of currently used BCG vaccines and provide evidence for a clinical trial comparing BCG strains.…”
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Responses of the metabolism of the larvae of Pocillopora damicornis to ocean acidification and warming. by Emily B Rivest, Gretchen E Hofmann

“…Larvae were incubated for 6 hours in seawater containing combinations of CO2 concentration (450 and 950 µatm) and temperature (28 and 30°C). …”
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ADDITIVES TO BITUMENS by N. A. Belova, L. P. Korotovenko, N. A. Strakhova

“…Improving the quality of road bitumen is currently particularly relevant, since allows you to extend the life of road asphalt coatings with the ever-increasing fleet of cars. …”
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Image fusion algorithm for the collaborative use of unmanned aerial vehicles by N. V. Levshonkov, I. M. Nafikоv, Y. V. Laryukhina

“…Currently, the applicable scope of unmanned aircraft application is increasingly expanding. …”
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Enhancing CO₂ Fixation in Microalgal Systems: Mechanistic Insights and Bioreactor Strategies by Zhongliang Sun, Chenmei Bo, Shuonan Cao, Liqin Sun

“…Microalgae are small, single-celled, or simple multicellular organisms that contain Chlorophyll a, allowing them to efficiently convert CO₂ and water into organic matter through photosynthesis. …”
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A Review: Classification, Chemical Compositions and Antioxidant Properties of Red, Brown and Green Macroalgae by Ngoc Trang Thuy Nguyen, Thanh Men Tran

“…Since algal products' antioxidant properties and nutritional benefits have been increasingly recognized, their properties as antioxidants require further investigative studies. …”
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Precolumn Derivatization High-Performance Liquid Chromatography for Determination of Perfluorocarboxylic Acids in Catalytic Degradation Solutions by Liping Yang, Binbin Sun, Haochen Cui, Lingyan Zhu, Guoqiang Shan

“…There are a lot of measurement requests in currently increasing degradation studies of PFCAs, which usually rely on expensive liquid chromatography-mass spectrometry (LC-MS). …”
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Genetic diversity of the Plasmodium falciparum GTP-cyclohydrolase 1, dihydrofolate reductase and dihydropteroate synthetase genes reveals new insights into sulfadoxine-pyrimethamin... by Anna Turkiewicz, Emilia Manko, Colin J Sutherland, Ernest Diez Benavente, Susana Campino, Taane G Clark

“…Amplifications are more likely to be present in isolates with a greater accumulation of pfdhfr and pfdhps substitutions (median of 1 additional mutations; P<0.00001), and there was evidence that the frequency of pfgch1 variants may be increasing in some African populations, presumably under the pressure of SP for chemoprophylaxis and anti-folate containing antibiotics used for the treatment of bacterial infections. …”
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Schistosome egg antigen stimulates the secretion of miR-33-carrying extracellular vesicles from macrophages to promote hepatic stellate cell activation and liver fibrosis in schist... by Xin Qi, Yanan Pu, Fanyan Chen, Liyang Dong, Yongbin Ma, Junling Wang, Guo Yin, Di Lu, Xiaojun Chen, Jifeng Zhu, Yalin Li, Sha Zhou, Chuan Su

“…Mechanistically, EVs derived from SEA-stimulated Mφ contained increased miR-33, which were transferred into HSCs and subsequently upregulated autocrine TGF-β1 in HSCs through targeting and downregulating SOCS3 expression, thereby promoting HSC activation. …”
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Determination of Microbial Properties of Freeze Dried Traditional Cheese by Tuba Büyüksırıt Bedir, Hakan Kuleaşan

“…Various technologies are currently being used for the drying of cheese and efforts are still being made to develop new methods. …”
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Study on the Denitration Performance of Sulfuric Acid-Modified Columnar Catalysts Derived from Rare Earth Tailings by Qie Junmao, Xu Tong, Zhao Zefeng

“…Currently, the massive accumulation of Bayan Obo rare earth tailings in Baotou City, Inner Mongolia, has imposed significant pressure on the local ecological environment. …”
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Regenerative and Innovative Utilization of Coffee Residue and Waste Cooking Oil: Improving Rheological Properties of Recycled Asphalt by Ruipeng Zhu, Chunhua Hu

“…Currently, there is limited research on the utilization of spent coffee grounds (SCG) in asphalt pavement. …”
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Self-sufficiency in the healthcare workforce: a system dynamics model of the domestic and foreign educated nursing and midwifery workforce in Ireland by Terence Hynes, Paul Caulfield, Peter O’Connor, John Cullinan

“…Ireland, the context for this study, currently relies heavily on foreign educated nurses and midwives to meet its demand, with Government policy moving towards a domestic recruitment model. …”
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Engineered extracellular vesicles for delivering functional Cas9/gRNA to eliminate hepatitis B virus cccDNA and integration by Wanjia Zeng, Liwei Zheng, Yukun Li, Jing Yang, Tianhao Mao, Jing Zhang, Yanna Liu, Jing Ning, Ting Zhang, Hongxin Huang, Xiangmei Chen, Fengmin Lu

“…Our results demonstrated that engineered EVs containing Cas9/gRNA and VSV-G can effectively reduce viral antigens and cccDNA levels in the HBV-replicating and infected cell models. …”
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A Systematic Review Examining the Association of Falls With Diabetes‐Related Foot Ulcers by Mike Wu, Mallika Sinha, Chanika Alahakoon, Kristen S. Barratt, Shivshankar Thanigaimani, Jonathan Golledge

“…A meta‐analysis showed high heterogeneity between studies (I2 = 95%) and an increased risk of falls in people with DFU (risk ratio 2.25 and 95% CI 1.05–4.84). …”
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Cytomegalovirus-Specific T Cells from Third-Party Donors Successfully Treated Refractory Cytomegalovirus Retinitis after Unrelated Umbilical Cord Blood Transplantation by Na Li, Guangyu Sun, Lihua Zhu, Kang Ding, Huilan Liu, Xiaoyu Zhu, Baolin Tang, Wen Yao, Xiang Wan, Liangquan Geng, Ping Qiang, Kaidi Song, Changcheng Zheng, Zimin Sun, Juan Tong

“…Umbilical cord blood (UCB) transplants (UCBTs) are becoming increasingly common in the treatment of a variety of hematologic and nonhematologic conditions. …”
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Demographic responses of hybridizing cinquefoils to changing climate in the Colorado Rocky Mountains by Kelly A. Carscadden, Daniel F. Doak, Meagan F. Oldfather, Nancy C. Emery

“…Our findings demonstrate that hybrids in this system are neither intrinsically unfit nor universally more vigorous than parents, suggesting that the demographic consequences of hybridization are context‐dependent. Our results also imply that shifts to warmer and drier conditions could have particularly negative repercussions for P. pulcherrima, which is currently the most abundant taxon in the study area, possibly as a legacy of more favorable historical climates. …”
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Is South Africa ready for point-of-care, non-sputum tests for TB diagnosis? An assessment of end-user perceptions on a novel urine test and tongue swab for TB testing by Nasiphi Mqedlana-Ntombela, Vanessa Fargnoli, Salome Charalambous, Kavindhran Velen, Sonjelle Shilton, Violet Chihota

“…Novel non-sputum sample types currently under development can increase TB testing, however there is limited knowledge on end-user perceptions on these tests. …”
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Evolution of taxis responses in virtual bacteria: non-adaptive dynamics. by Richard A Goldstein, Orkun S Soyer

“…We currently lack a full understanding of the different pathway structures and dynamics and how this integration is achieved. …”
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Ipomoea batatas (L.) Lam. cultivation in the conditions of light culture in vitro and ex vitro by E. A. Kalashnikova, R. N. Kirakosyan, A. V. Gushchin, K. G. Abubakarov, N. N. Sleptsov, S. K. Temirbekova, A. P. Glinushkin, O. V. Meleshina, N. Ya. Rebouh, M. M. Tareeva

“…Interest in this substance is justified by its valuable properties – it is a good immunomodulator, cleanses the body of toxins, radionuclides, "bad" cholesterol, promotes the assimilation of useful trace elements necessary for human life. Inulin is contained in plants such as jerusalem artichoke, chicory, as well as in sweet potatoes, the popularity of which is increasing every year. …”
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