In Vitro Efficacy of PEI-Derived Lipopolymers in Silencing of Toxic Proteins in a Neuronal Model of Huntington’s Disease by Luis C. Morales, Luv Modi, Saba Abbasi Dezfouli, Amarnath Praphakar Rajendran, Remant Kc, Vaibhavi Kadam, Simonetta Sipione, Hasan Uludağ

“…<b>Results:</b> Here, we show that engineered lipopolymers can be used as delivery vehicles for specific siRNAs, decreasing the transcription of the mutated gene, as well as the muHTT protein production and aggregation, with Leu-Fect C being the most effective candidate amongst the assessed lipopolymers. …”
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Development of an easy non‐destructive particle isolation protocol for quality control of red blood cell concentrates by Marine Ghodsi, Anne‐Sophie Cloos, Anaïs Lotens, Marine De Bueger, Patrick Van Der Smissen, Patrick Henriet, Nicolas Cellier, Christophe E. Pierreux, Tomé Najdovski, Donatienne Tyteca

“…Nevertheless, there is currently no standardized isolation protocol. In a previous publication, we developed a reproducible ultracentrifugation‐based protocol (20,000 × g protocol) that allows to classify red blood cell concentrates into three cohorts according to their vesiculation level. …”
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Framing the Open (Urban) Project: Insights from Landscape and Ecology by Jeannette Sordi

“…Currently, the threat posed by climate change and the increasing investment from cities on creating and repurposing open spaces and infrastructure, is feeding a renovated interest in landscape design. …”
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Learning the TEI in a Digital Environment by Stella Dee

“…This article provides a brief overview of currently-available digital resources for learning to understand and use the TEI Guidelines. …”
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Artificial Intelligence and Machine Learning at the Intersection of Privacy and Archives by Iori Khuhro, Erin Gilmore, Jim Suderman, Darra L. Hofman

“…The study revealed three major themes: 1) the challenges of – and possibilities beyond – defining “privacy” and “AI”; 2) the need for context-sensitive ways to manage privacy and access decisions; and 3) the lack of adequate “success measures” for ensuring the actual fitness for purpose of privacy AI solutions in the archival context. …”
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Preparation, mechanical, and thermal properties of CrNbO4: A novel dual-functional scale to protect RHEAs from oxidation and thermal attack by Shuang Zhang, Jian Zhang, Xiaohui Wang, Huimin Xiang, Cheng Fang, Wei Xie, Yanchun Zhou

“…Interestingly, the room temperature thermal conductivity of CrNbO4 is 1.09 W·m−1·K−1 and decreases to 0.45 W·m−1·K−1 at 1473 K, which is lower than that of most of the currently well-known thermal insulation materials. …”
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Effectiveness of Physiotherapy and Occupational Therapy after Traumatic Brain Injury in the Intensive Care Unit by Stephanie Hellweg

“…Physiotherapy and occupational therapy are frequently administered in intensive care units (ICUs) after traumatic brain injury (TBI) to promote recovery. The increasing economic pressure and the growing need for evidence of therapeutic effectiveness are reasons for reviewing the currently available scientific data. …”
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The water level regime of periglacial lakes during the growth stage (the lakes of the Tavan-Bogdo-Ola mountain massif, South-Eastern Altai) by V. A. Rasputina, G. V. Pryakhina, D. A. Ganyushkin, D. V. Bantcev, N. A. Paniutin

“…Assessment of the dynamics of high-altitude glacial lakes is becoming increasingly important in the context of modern climate instability. …”
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Model of regional human resource management as a tool for sustainable development of the socioeconomic system by Veronika S. Zhukova

“…Integration of regional human resource management into the process of achieving goals of national economy is of particular importance in the context of the need for a comprehensive and systemic approach to the development of territories. …”
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Implementation of the National Project «Labor Productivity and Employment Support» in the Perm Region: Facts, Problems, Prospects by T. V. Alexandrova, V. L. Popov

“…In the context of the reorientation of the Russian economy towards an innovative development path, the issue of increasing labor productivity has become an important part of state policy.Currently, the country is implementing a large-scale national project «Labor productivity and employment support». …”
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Based on the Logistic regression analysis method, the carbon emission indicators of a certain province are analyzed Analysis and research by Hu Zhengxi

“…China is currently in an important period of strategic opportunities, experiencing rapid economic development, gradual social transformation, and increasingly prominent environmental issues.Achieving sustainable development of the economy, society, and environment is currently the most important task. …”
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DEVELOPMENT PROSPECTS OF THE RUSSIAN MARKET OF TECHNICAL SERVICING AND REPAIR IN THE СONTEXT OF A PANDEMIC by O. A. Tettsoeva

“…Currently, at a time of decreasing automotive production caused by the suspension of the plants in the period of lockdown, the reduction in purchasing power of communities connected with the risk of unemployment occurrence in consequence of business failures, the decline in wages and lower vacancy rates, is foreseen reduced demand for new cars against the background of significant increase in sales volumes in the used cars market segment and, therefore, sharp increase in demand for car services performing technical servicing and repair. …”
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Identification, Evolution and Expression Analyses of the Hox Family in Procambarus clarkii by Xiaoyu WEI, Qian HU, Zemao GU, Yanhe LI

“…Homeobox genes are ubiquitous in eukaryotic genomes and can be transcribed into a homeodomain of approximately 60 amino acids. Hox genes are currently the most studied class of homeobox genes. …”
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Compensação ambiental: da contradição à valoração do meio ambiente no Brasil / Environmental compensation: from the contradiction to the valuation of the environment in Brazil... by Rafael Oliveira Fonseca

“…As currently the state has been conducting massive investments in sectors considered strategic for economic growth, environmental vector has been extremely pressed and increasingly valued. …”
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Global Citizenship Education and ELT? by Michael Koppel

“…Using qualitative content analysis, the interviews reveal that pre-service teachers as experts-in-the-making show great enthusiasm towards global citizenship education in the context of English language teaching. Particularly the promotion of the global community as well as fostering their future students’ capabilities to engage with an increasingly globalized world were shared goals among the interviewees. …”
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Knowledge gaps and research opportunities in the light of the European Union Regulation on deforestation-free products by Piermaria Corona, Valerio Di Stefano, Angelo Mariano

“… In recent decades the need for new legislative and technical tools to counter the main threats to the world's forests has been increasingly felt. Currently, the European Union (EU) has moved towards the implementation of the new deforestation-free products Regulation (EUDR) which builds on the experience gained by Member States and EU institutions with the Regulation on timber trade. …”
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A Survey on Computational Methods in Drug Discovery for Neurodegenerative Diseases by Caterina Vicidomini, Francesco Fontanella, Tiziana D’Alessandro, Giovanni N. Roviello

“…Currently, the age structure of the world population is changing due to declining birth rates and increasing life expectancy. …”
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Health Technology Assessment in China’s Health Care Sector: Development and Applications by Wudong Guo, Peimeng Wang, Yuzheng Zhang, Xue Li, Yaoling Wang, Kun Zhao, Francis Ruiz, Rui Li, Feiyi Xiao, Xuefei Gu, Mao You, Qiang Fu

“…Currently, HTA plays an indispensable part in the reform of China’s health care and medical insurance system, especially in the formulation and adjustment of the National Reimbursement Drug List (NRDL). …”
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Psychological Service in the Education System as a Phenomenon by Irina V. Dubrovina

“…The article highlights a relevant problem of upbringing students within modern school education as considered in the context of the role of interaction between psychology and pedagogy. …”
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Project-based action in the structure of educational-game environments by N.V. Gromyko, Y.V. Gromyko, S.P. Usoltsev

“…Currently, the problem of declining motivation among school students in the context of the modern education system, which is heavily focused on preparing for the Unified State Exam (USE) and Olympiads, is widely recognized. …”
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