Neutrophil-to-Lymphocyte ratio as surrogate for JAK2V617F suppression and event-free survival in polycythemia vera by Tiziano Barbui, Arianna Ghirardi, Victoria Empson, Francesca Fenili, Giuseppe Gaetano Loscocco, Annalisa Condorelli, Alessandra Iurlo, Daniele Cattaneo, Elena Rossi, Valerio De Stefano, Paola Guglielmelli, Christoph Klade, Heinz Gisslinger, Alessandro Rambaldi, Joseph M. Scandura, Alessandro Maria Vannucchi

“…Abstract Chronic systemic inflammation is a key driver of polycythemia vera (PV) progression, but the immunomodulatory effects of current treatments remain poorly defined. The neutrophil-to-lymphocyte ratio (NLR) is an accessible biomarker of systemic inflammation proven in other contexts, but its role in monitoring PV disease activity has not been established. …”
Get full text

Key Barriers to Personalized Learning in Times of Artificial Intelligence: A Literature Review by Gina Paola Barrera Castro, Andrés Chiappe, María Soledad Ramírez-Montoya, Carolina Alcántar Nieblas

“…Personalized learning (PL) has emerged as a promising approach to address diverse educational needs, with artificial intelligence (AI) playing an increasingly pivotal role in its implementation. This systematic literature review examines the landscape of PL across various educational contexts, focusing on the use of AI and associated challenges. …”
Get full text

TRENDS IN THE EVOLUTION OF ORGANIC AGRICULTURE AT THE GLOBAL LEVEL - A BRIEF REVIEW by Elena BONCIU

“…Therefore, ecological agriculture means respect for people and for nature. In this context, the objective of this paper was to briefly evaluate the trends of organic agriculture sector at global level, in the context where the development of this system is motivated by the increasing demand of consumers for food quality and safety in consumption. …”
Get full text

Advancing multimodal teaching: a bibliometric and content analysis of trends, influences, and future directions by Xingrong Guo, Siyu Chen, Yiming Guo

“…This study not only highlights the current trends in multimodal teaching but also proposes a conceptual framework and future research directions, offering valuable insights for the adaptation of educational practices in increasingly digital and multimodal contexts.…”
Get full text

Optimising the secondary use of primary care prescribing data to improve quality of care: a qualitative analysis by Robert A Verheij, Niek Klazinga, Erica Barbazza, Lotte Ramerman, Dionne Kringos

“…Important differences in the types of prescribing information needed by micro-meso-macro context are found, though the extent to which current indicators address these varies by prescription type. …”
Get full text

A guide to evade hallucinations and maintain reliability when using large language models for medical research: a narrative review by Sangzin Ahn

“…Large language models (LLMs) are increasingly prevalent in medical research; however, fundamental limitations in their architecture create inherent reliability challenges, particularly in specialized medical contexts. …”
Get full text

Being there but where? Sense of presence theory for virtual reality applications by Stefano Triberti, Caterina Sapone, Giuseppe Riva

“…As immersive technologies become increasingly prevalent in shared environments and sensitive contexts such as education and healthcare, this more sophisticated understanding of presence becomes crucial for designing effective virtual experiences. …”
Get full text

Latest trends on interplay of autophagy, adipose tissue, and gut microbiota in obesity-related metabolic disorders by Claudette Butoyi, Muhammad Asad Iqbal, Isaac Duah Boateng

“…Conversely, pharmacologically induced Atg, exemplified by rapamycin administration, enhances insulin sensitivity by 15–25 % in rodent models. (2) Alterations in gut microbial composition, characterized by a 40 % decrease in Bacteroidetes and an increase in Firmicutes, correlate with elevated visceral adiposity and systemic inflammation. …”
Get full text

Clustering Analysis of Turkish Maritime Transportation Sector by Cengiz Bahadır Karahan, Levent Kırval, Çağrı Çınar

“…Turkey is a maritime country with its current fleet, geographical location, young population and growth potential. …”
Get full text

Addressing ‘wicked complex problems’: Qualitative understandings of sexual violence prevention in male-dominated industries by Sarah Vrankovich, Sharyn Burns, Giselle Woodley, Jacqueline Hendriks

“…This research aims to provide an understanding of current sexual violence prevention initiatives within the Australian mining sector, offering recommendations for future approaches tailored to industries and contexts with similar dynamics.…”
Get full text

Essential Pieces of the Puzzle: The Roles of VEGF and Dopamine in Aging by Melanie B. Thompson, Sanjay P. Tirupattur, Nandini Vishwakarma, Laxmansa C. Katwa

“…Aging is a well-known, complex physiological process characterized by progressive functional decline and increased susceptibility to disease, particularly in the cardiovascular and nervous systems. …”
Get full text

Is social theory losing its relevance? A call for social impact and cocreation from dialogic sociology by Elisabeth Torras-Gómez, Mar Joanpere, Carmen Elboj, Mengna Guo, Esther Oliver, Ane Lopez de Aguileta, Marta Soler-Gallart

“…Abstract Currently, the interest in and use of social theory by policy-makers, organizations, and citizens have decreased worldwide. …”
Get full text

Applications of Indocyanine Green in Breast Cancer for Sentinel Lymph Node Mapping: Protocol for a Scoping Review by Feryal Kurdi, Yahya Kurdi, Igor Vladimirovich Reshetov

“…ObjectiveThe objective of this scoping review is to evaluate the current literature on the use of ICG in SLN mapping for patients with breast cancer. …”
Get full text

Use of participatory forum theatre to explore HIV/AIDS issues in the workplace by Emma Durden, Dominique Nduhura

“… The continued success of entertainment education programmes around the world has seen an increase in the use of theatre for HIV/AIDS interventions. …”
Get full text

Returns to Higher Education in Mexico: A Cross-Sectional Analysis, 2010–2024 by Janeth Yadira Rodríguez Galván, Juan Francisco Islas Aguirre

“…This study evaluates the socioeconomic effects of educational policies implemented between 2010 and 2024 within the context of the Fourth Industrial Revolution, focusing on the labor demand for professionals with advanced competencies. …”
Get full text

The Propensity to Cycle Tool: An open source online system for sustainable transport planning by Robin Lovelace, Anna Goodman, Rachel Aldred, Nikolai Berkoff, Ali Abbas, James Woodcock

“…Getting people cycling is an increasingly common objective in transport planning institutions worldwide. …”
Get full text

Identifying the role of route choice behavior of motorcycle riders in microscopic simulation modeling under mixed traffic conditions by Siti Raudhatul Fadilah, Hiroaki Nishiuchi, An Minh Ngoc

“…Overall, this study contributes methodologically by increasing model precision and practical insights into managing heterogeneous traffic environments, highlighting the transformative potential of traffic information systems and advocating for broader implementation in similar motorcycle-centric regions, which currently still rarely extend beyond toll roads. …”
Get full text

Development of Contextual English Language Teaching Materials Based on Sport Coaching Education by Kristian Burhan, Helfany Amsa, Indri Astuti, Sherly Franchisca

“…Despite the prominent role of English in the sports industry, few studies have explored the demand for English competence among future sport coaches, especially in the context of an increasingly globalized sporting domain where communication is becoming key in diverse trading environments. …”
Get full text

Generational diversity in nursing practice environments – scoping review by Diana Sanches, Soraia Pereira, Susana Castro, Mariana Mendes, Eduardo Santos, Olga Ribeiro

“…Although the findings differ, it’s undeniable that each generation has a unique and valuable role, and it’s essential to promote an effective balance between generations to build a diverse workforce capable of adapting to different challenges in professional contexts. Conclusion Organizations should acknowledge the importance of creating inclusive professional practice environments, where both current and future generations can contribute to providing quality care. …”
Get full text

Long-Term Exposure to Primary Traffic Pollutants and Lung Function in Children: Cross-Sectional Study and Meta-Analysis. by Francesco Barone-Adesi, Jennifer E Dent, David Dajnak, Sean Beevers, H Ross Anderson, Frank J Kelly, Derek G Cook, Peter H Whincup

“…Moreover, we placed the results for NO2 in context with a meta-analysis of published estimates of the association.…”
Get full text