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4701
<i>MAGE-C1</i> gene and mage-c1 protein expression comparison in primary multiple myeloma patients
Published 2022-04-01“…Single factor analysis showed that patients with decreased MAGE-C1 gene and mage-c1 protein expression levels achieved a significantly higher antitumor response to bortezomib-containing regimens, while high expression was accompanied by refractoriness to bortezomib.…”
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4702
Social Aspects of Dementia Prevention from a Worldwide to National Perspective: A Review on the International Situation and the Example of Italy
Published 2019-01-01“…Dementia is a growing health concern worldwide with no treatment currently available, but only symptomatic medication. …”
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4703
Parentage assignment in black soldier fly (Hermetia illucens) using genotyping-by-sequencing
Published 2025-06-01“…However, this is not currently feasible in mass reared insects like BSF. …”
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4704
SFX-01 is therapeutic against myeloproliferative disorders caused by activating mutations in Shp2
Published 2025-07-01“…SFX-01, an α-cyclodextrin-stabilized sulforaphane complex currently in clinical development, covalently adducts cysteine residues. …”
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4705
Plant Cell Culture-Derived Saponin Adjuvant Enhances Immune Response Against a Stabilized Human Metapneumovirus Pre-Fusion Vaccine Candidate
Published 2024-12-01“…Results: In mice, TLR4 agonist containing adjuvant formulations with plant cell-produced QS-21 performed equally to licensed adjuvant AS01 containing tree-bark-extracted QS-21 and demonstrated a significant increase in immunogenicity against HMPV preF compared to the unadjuvanted control. …”
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4706
Molecular identification of Moniliophthora roreri isolates from cocoa orchards in Norte de Santander, Colombia
Published 2016-01-01“…The disease destroys the cocoa pod and crop production decreases, the losses reach up to 60% in the department of Norte de Santander. …”
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4707
Petrochemical characteristics of ancient weathering crusts with scandium concentrations in the Nakyn kimberlite field
Published 2024-11-01“…Currently, this Formation is considered the most promising for scandium mineralization compared to other areas in the Malo-Botuobinsky and Ygyattinsky diamond-bearing regions of Yakutia with the identified scandium concentrations. …”
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4708
Access to Substituted Tricyclic Heteroarenes by an Oxidative Cyclization Reaction and Their Antifungal Performance
Published 2025-02-01“…<b>Background/Objectives</b>: Fungal pathogens are increasingly developing concerning resistance against the currently available antifungal drugs, which creates a constant demand for new antifungal agents. …”
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4709
The Profile of Multidrug Tuberculosis Regimen and Treatment Outcomes in Pulmonary MDR-TB Patients at the Tertiary Referral Hospital Dr. Soetomo, East Java, Indonesia: A Seven-Year...
Published 2024-01-01“…The treatment outcome profile of MDR-TB patients shows the average percentage of cured (15%), died (12%), lost-to-follow-up cases (27%), moved to an individualized regimen or a different health facility (42%), and currently in the evaluation stage (4%). Overall from January 2017 to July 2022, the number of LTFU cases decreased (42, 46, 29, 19, 8, 4)%. …”
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4710
HIV-1 Drug Resistance Mutations: Potential Applications for Point-of-Care Genotypic Resistance Testing.
Published 2015-01-01“…The increasing prevalence of acquired and transmitted HIV-1 drug resistance is an obstacle to successful antiretroviral therapy (ART) in the low- and middle-income countries (LMICs) hardest hit by the HIV-1 pandemic. …”
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4711
THE SCOPE OF GLOBALIZATION AND ITS IMPACT ON THE ECONOMIC AND FINANCIAL-BANKING SECTOR
Published 2011-04-01“…The general term used to characterize this increasing interdependence of the human society is that of globalization.…”
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4712
Advances in CO-SCR Catalysts and Reaction Mechanisms
Published 2025-04-01“…It also analyzes the reaction mechanisms and approaches for mitigating catalyst poisoning under different reaction conditions, such as oxygen-rich, water-containing, sulfur-containing, and various complex environments. …”
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4713
Preparation, characterization and activity verification of xylooligosaccharides from plantain straw
Published 2024-12-01“…Currently, the utilization value of plantain straw is low. …”
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4714
High-performance liquid chromatography–tandem mass spectrometry for simultaneous determination of 23 antidepressants and active metabolites in human serum and its application in th...
Published 2025-03-01“…Currently, the treatment of depression mainly relies on drug intervention. …”
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4715
Application of alternative <i>de novo</i> motif recognition models for analysis of structural heterogeneity of transcription factor binding sites: a case study of FOXA2 binding sit...
Published 2021-03-01“…The combination of these four models allowed a signif icant increase in the fraction of recognized peaks compared to that for the sole PWM model: the increase was 26.3 %. …”
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4716
Changes in Farm Supply Voltage Caused by Switching Operations at a Wind Turbine
Published 2024-11-01“…Renewable electricity sources are now widely used worldwide. Currently, the most common sources are those that use energy contained in biomass, water, sun, and wind. …”
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4717
Camelia seed and its functional properties promising for dermatological applications
Published 2025-07-01“…While camellia leaves have established industrial applications, camellia seed oil is emerging as a significant source for functional use in nutraceuticals. However, there is currently insufficient evidence supporting its innovative potential in this field. …”
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4718
Autonomous, miniature research station (lab-payload) for the nanosatellite biological mission: LabSat
Published 2025-08-01“…Abstract There is an increase in demand for bio-nanosatellites and biomedical methodologies as a result of experiments conducted in microgravity and radiation conditions. …”
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4719
Historical shipwrecks in international waters contributes to coastal pollution
Published 2024-11-01“…Moreover, it was sunk to a depth of approximately 5,000 m with a cargo containing rubber, tin, and wolframite. Tin is currently considered a strategic metal, with prices rising from USD 13,375/t in March 2020 to USD 34,462/t in May 2021. …”
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4720
Potential Application of Camel Milk as a Therapeutic Ingredient in Bath Soaps and Shampoos
Published 2024-01-01“…Besides naturally formulated cosmetics being biodegradable, they also contain ingredients which are chemically beneficial to human skin. …”
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