Hypoxia induces an immunodominant target of tuberculosis specific T cells absent from common BCG vaccines. by Hannah Priyadarshini Gideon, Katalin Andrea Wilkinson, Tige R Rustad, Tolu Oni, Heinner Guio, Robert Andrew Kozak, David R Sherman, Graeme Meintjes, Marcel A Behr, Hans Martin Vordermeier, Douglas Brownlee Young, Robert John Wilkinson

“…In addition, the IL-2 response to Rv1986 was significantly lower in HIV-TB co-infected persons than in HIV uninfected persons, and significantly increased during antiretroviral therapy. These findings demonstrate that Rv1986 is an immunodominant target of memory T cells and is therefore of relevance when considering the partial efficacy of currently used BCG vaccines and provide evidence for a clinical trial comparing BCG strains.…”
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Coordinated regulation of nuclear receptor CAR by CCRP/DNAJC7, HSP70 and the ubiquitin-proteasome system. by Yoav E Timsit, Masahiko Negishi

“…Induction of HSP70 levels by heat shock also increased cytoplasmic CAR levels, similar to the effect of MG132. …”
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Schistosome egg antigen stimulates the secretion of miR-33-carrying extracellular vesicles from macrophages to promote hepatic stellate cell activation and liver fibrosis in schist... by Xin Qi, Yanan Pu, Fanyan Chen, Liyang Dong, Yongbin Ma, Junling Wang, Guo Yin, Di Lu, Xiaojun Chen, Jifeng Zhu, Yalin Li, Sha Zhou, Chuan Su

“…Mechanistically, EVs derived from SEA-stimulated Mφ contained increased miR-33, which were transferred into HSCs and subsequently upregulated autocrine TGF-β1 in HSCs through targeting and downregulating SOCS3 expression, thereby promoting HSC activation. …”
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Study on the Denitration Performance of Sulfuric Acid-Modified Columnar Catalysts Derived from Rare Earth Tailings by Qie Junmao, Xu Tong, Zhao Zefeng

“…Currently, the massive accumulation of Bayan Obo rare earth tailings in Baotou City, Inner Mongolia, has imposed significant pressure on the local ecological environment. …”
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Regenerative and Innovative Utilization of Coffee Residue and Waste Cooking Oil: Improving Rheological Properties of Recycled Asphalt by Ruipeng Zhu, Chunhua Hu

“…Currently, there is limited research on the utilization of spent coffee grounds (SCG) in asphalt pavement. …”
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Lab-in-a-Tip: a multiplex immunoassay platform based on a self-assembled barcoded protein array by Yiran He, Min Jiang, Zhenlong Liang, Zhaoxu Luo, Jingyi Qin, Ye Shen, Yayun Gu, Xiaodong Ma, Hong Wang, Xin Li, Ying Shi, Yanhua Chen, Kefeng Pu, Jiong Li

“…Abstract High throughput immunoassay is increasingly crucial for both scientific and clinical applications. …”
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Acute beneficial effects of a functional energy shot on cognitive performance and mood states during cognitively demanding task performance: a randomized, double-blind, placebo-con... by Olivia K. O’Shea, Olivia K. O’Shea, Nathan Lawley, Anna Azzopardi, Allison Gutkowski, Michelle Murphy Niedziela, Rachel Horn, David O. Kennedy, Jason Adamson

“…IntroductionFunctional beverages are increasingly popular but it is important to validate their purported effects through research. …”
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Challenges to generating political prioritization for adolescent sexual and reproductive health in Kenya: A qualitative study. by Maricianah Atieno Onono, Claire D Brindis, Justin S White, Eric Goosby, Dan Odhiambo Okoro, Elizabeth Anne Bukusi, George W Rutherford

“…We examined factors that have shaped the lack of current political prioritization of adolescent SRH service provision.…”
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Review: Application of Protein-Based Raw Materials in Health Foods in China by Hao Duan, Gaigai Liu, Jiaqi Liu, Zhuoye Wang, Shuyuan Bao, Xinyue Chang, Wenjie Yan

“…Finally, based on these studies, this paper discusses suggestions for raw protein materials in the future development of health food in China and also discusses the limitations of the current research in this review.…”
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The Effect of Adzuki Bean Extract on Antioxidant and Inflammatory Indices in Diabetic Rats by Ewelina Król, Halina Staniek, Zbigniew Krejpcio, Dawid Szczepankiewicz, Małgorzata Gumienna, Barbara Górna

“…In order to achieve this goal, plant materials that contain compounds with high antioxidant potential, exhibit digestive enzyme inhibiting activity, or contain substances that improve insulin sensitivity are selected. …”
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Sustainable concrete manufactured with mixed recycled aggregate and biomass bottom ash, replacing aggregate and cement to a high percentage by M. Rosales, J. Rosales, S. Moreno, F. Agrela, J.L. Díaz-López

“…Given the current problem of CO2 emissions and the overexploitation of natural resources, it is essential to make a change in the materials typically used for concrete manufacturing. …”
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Capturing microalgae within aerosols provides carbon capture bio-functionality by Elbaraa Elghazy, Matt M.J Davies, Nicholas T.H Farr, Cornelia Rodenburg, Jon R. Willmott, Jagroop Pandhal

“…Inspired by recent evidence that 95 % of CO2 from aerosol emissions from an Australian forest fire was captured by algae in the Southern Ocean, as well as the ability of algae to be transported within aerosols, we propose a novel technique for CO2 sequestration based on creating aerosols containing metabolically active cyanobacteria. Using aerosols as a microenvironment for Synechocystis cells enables a significant increase in gas-liquid-interfacial-surface-area while reducing the volume of water required. …”
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Availability of trace minerals in feed ingredients and supplemental sources (inorganic, organic, and nano) in broiler chickens by Junhyung Lee, Minju Kim

“…At d 15 of age, a total of 480 birds, one-day-old Ross 308 males, were used in the current trial and housed in metabolic cages for chickens. …”
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miR-34a-5p modulation of polycystic ovary syndrome via targeting the NOTCH signaling pathway by Kexin Zhang, Xiaomeng Wang, Fang Liu, Hong Lin, Yan Wang, Min Zhao, Xiaofei Wang, Yijing Chu, Lin Xu

“…Abstract Purpose Polycystic ovary syndrome (PCOS) is currently recognized as a condition that affects several systems in the body, including the reproductive, endocrine, and cardiovascular systems. …”
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MEANS AND METHODS OF STIMULATION OF SALIVATION (LITERATURE REVIEW) by N.O. Riabushko

“… Currently, a large number of tools and methods are proposed to reduce dryness in the mouth and restore the deficiency of biologically active substances entering the mouth with saliva. …”
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NMDA Receptor–Mediated Ca2+ Flux Attenuated by the NMDA Receptor/TRPM4 Interface Inhibitor Brophenexin by Jordan Casby, Benjamin M. Gansemer, Stanley A. Thayer

“…Incubating cultures in Mg2+‐free buffer containing tetrodotoxin, 6‐cyano‐7‐nitroquinoxaline‐2,3‐dione, and bicuculline for 30 min inhibited NMDA‐evoked increases in intracellular Ca2+ concentration ([Ca2+]i) recorded at 22°C by 50% ± 18% and prevented inhibition by brophenexin. …”
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Impact of Metal Source Structure on the Electrocatalytic Properties of Polyacrylonitrile-Derived Co-N-Doped Oxygen Reduction Reaction Catalysts by Arseniy Kalnin, Ksenia Kharisova, Daniil Lukyanov, Sofia Filippova, Ruopeng Li, Peixia Yang, Oleg Levin, Elena Alekseeva

“…We have proposed a multifunctional active metal source strategy based on the cobalt complex with the ligand containing pyridine and azo-fragments. This complex simultaneously provides the nitrogenous environment for the Co atoms and acts as a blowing agent due to N₂ extrusion, thus increasing the surface area and porosity of the material. …”
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Novel Nanotechnology of TiO2 Improves Physical-Chemical and Biological Properties of Glass Ionomer Cement by Daniela Dellosso Cibim, Miki Taketomi Saito, Priscila Alves Giovani, Ana Flávia Sanches Borges, Vanessa Gallego Arias Pecorari, Orisson Ponce Gomes, Paulo Noronha Lisboa-Filho, Francisco Humberto Nociti-Junior, Regina Maria Puppin-Rontani, Kamila Rosamilia Kantovitz

“…Furthermore, regardless of TiO2 concentration, no significant effect was found on SR, whereas GIC-containing 7% TiO2 presented decreased SH values. Fluoride release lasted longer for the 5% and 7% TiO2 groups, and cell morphology/spreading and ECM composition were found to be positively affected by TiO2 at 5%. …”
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Research progress in intracranial artery dissections over past 25 years: a review and bibliometric analysis by Zixuan Zhou, Zixuan Zhou, Zixuan Zhou, Bingyang Qin, Yang Chen, Yang Chen, Yang Chen, Ren Li, Ren Li, Ren Li, Biao Yang, Biao Yang, Biao Yang, Ziao Li, Ziao Li, Ziao Li, Yongqiang Wu, Yongqiang Wu, Yongqiang Wu, Xiaogang Wang, Xiaogang Wang, Xiaogang Wang, Xiaolong Guo, Xiaolong Guo, Xiaolong Guo, Wenju Zhang, Wenju Zhang, Wenju Zhang, Yuanli Zhao, Geng Guo, Geng Guo, Geng Guo, Geng Guo, Geng Guo

“…Keyword analysis of the literature showed that “recanalization “reached the highest intensity of outbreaks, while “thrombectomy “,” outcome “, “risk “, and “diagnosis “showed an increase in citations in 2025, indicating that these subjects continue to be of significant interest.ConclusionThis study explores the evolving research trends and challenges in the area of IAD, presenting a thorough examination of both its historical and current research contexts. …”
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Digital augmentation of aftercare for patients with anorexia nervosa: the TRIANGLE RCT and economic evaluation by Janet Treasure, Katie Rowlands, Valentina Cardi, Suman Ambwani, David McDaid, Jodie Lord, Danielle Clark Bryan, Pamela Macdonald, Eva Bonin, Ulrike Schmidt, Jon Arcelus, Amy Harrison, Sabine Landau

“…Support for the diversity of carers of eating disorders (fathers, partners, siblings) in different cultural contexts across the spectrum of eating disorders The current model of carers support is designed for parents (particularly mothers) of white, highly educated patients with AN. …”
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