Pharmacometric in silico studies used to facilitate a national dose standardisation process in neonatology – application to amikacin by Verena Gotta, Julia Anna Bielicki, Paolo Paioni, Chantal Csajka, Dominic Stefan Bräm, Christoph Berger, Elisabeth Giger, Michael Buettcher, Klara M. Posfay-Barbe, John van den Anker, Marc Pfister

“…We aimed to demonstrate how such pharmacometric modelling and simulation can provide a scientific rationale for optimising drug doses in the context of the Swiss national dose standardisation project in paediatrics using amikacin as a case study. …”
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Effects of Ramadan on cognitive functions in young boys by Amira Miladi, Mohamed Ali Saafi, Imed Latiri

“…The study found that Ramadan fasting did not have an effect on various reaction times or on electro-physiological data, including P300 amplitude and latency. The current study, conducted with healthy children/adolescents, indicates that Ramadan fasting had no impact on various reaction times (SRT, CRT, NPRT), suggesting the preservation of information processing speed and decision-making, even in the face of increased task complexity. …”
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The effects of seismic activities following the 30 October 2020 Samos Island earthquakes in Izmir and its surrounding by Oya Ankaya PAMUKÇU, Ayça ÇIRMIK, Fikret DOĞRU, Ekrem TUŞAT, Fatih UYSAL, Hasan SÖZBILIR, Ufuk AYDIN, Özkan Cevdet ÖZDAĞ, Metehan ULUĞTEKIN, Fulya ÖZDEMIR, Zülfikar ERHAN

“…In this context, in order to determine the current deformation after the Samos Island earthquake that occurred on October 30, 2020, measurements were performed at six continuous GNSS stations in and around Izmir. …”
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Sustainable Public Health Policies: Understanding Influenza Vaccination Uptake Among College Students in a Changing Society by Keren Dopelt

“…The results indicated that prior vaccination was the strongest predictor of current influenza vaccine uptake (OR = 38.7, <i>p</i> < 0.001). …”
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Innovations in the Research of the Relationship of Mental and Reproductive Health: Changes in Personality Profiles in Young Women with Pregnancy Pathology and the Reflection of Obs... by Ramazan K. MAGOMEDOV, Akhmed A. UZAYEV, Ibrahim V. NURIEV, Murajan U. MADDINOV, Radikhan Y. SHADMANOV

“…Current research in this area dictates the existence of a two-way relationship between mental and reproductive health. …”
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Collaborative Housing in Chile by Valentina Augusta Cortés Urra

“…In Chile, there has been recent interest from resident groups, third sector organisations and the current government in promoting collective self-organised housing through specific programs. …”
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Healthcare workers’ perceptions of patient safety culture in emergency departments: a scoping review by Min Ji Kim, Ming Wei Jeffrey Woo

“…Objective This review aimed to map the concept of patient safety culture in emergency departments (EDs), describe the availability of evidence related to patient safety culture as assessed by healthcare workers, identify the key focus areas of existing studies and pinpoint gaps in the current literature.Design A scoping review followed a comprehensive methodological process that included five steps based on the framework developed by Arksey and O’Malley and updated by Peters et al.Eligibility criteria Studies encompassing original research and all pertinent published and grey literature within the last 15 years (2010–2024) that aligned with the population (healthcare workers), concept (patient safety culture) and context (emergency department) framework for this study were included.Data sources PubMed, CINAHL (EBSCOhost), WOS, Embase, MEDLINE (Ovid), and KISS databases were searched for original studies published between 2010 and 2024 that aligned with the topic of this study.Data extraction and synthesis Two researchers independently extracted data from 28 eligible articles using a predetermined data extraction tool. …”
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Assessment of the Status of <i>Cephalanthera longifolia</i> Populations in Lithuania Derived from a Single-Census Study by Laurynas Taura, Zigmantas Gudžinskas

“…Therefore, the ratio of generative to vegetative individuals reflects current habitat conditions rather than long-term population trends.…”
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Testosterone-induced erythrocytosis: addressing the challenge of metabolic syndrome and widely prescribed SGLT2-inhibitor drugs by Federica Tramontana, Azmi Mohammed, Yaasir H Mamoojee, Richard Quinton

“…Crucially, they also increase haematocrit by promoting haematopoiesis. This review focuses on the current best evidence for managing erythrocytosis, in the context of more prevalent obesity and prescriptions of testosterone and SGLT2i in this population. …”
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Importance of Cheese Whey Processing: Supplements for Sports Activities – a Review by Patricia Fassina, Gabriela Quadros Nunes, Fernanda Scherer Adami, Márcia Inês Goettert, Claucia Fernanda Volken de Souza

“…Whey protein (WP) is a highly nutritious, commercially available alternative food source that is used primarily as a food supplement by athletes and physically active individuals to provide them with essential amino acids and bioactive peptides, and additional benefits have been attributed to WP consumption. In this context, the objective of this review was to explore current evidence regarding the consumption of different WP supplements in sports nutrition to elucidate their efficiency in affecting muscle hypertrophy, physical performance, response to muscle injury, weight loss, and body composition changes. …”
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The Immune Environment in Colorectal Adenoma: A Systematic Review by Ugne Silinskaite, Jurate Valciukiene, Matas Jakubauskas, Tomas Poskus

“…<b>Methods:</b> In this systematic review, we aim to provide a thorough analysis of the current research examining the immune infiltration patterns in sporadic colorectal adenoma tissues in the context of immune cell-based, cytokine-based, and other immunological factor-related changes along the conventional adenoma–carcinoma sequence. …”
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Data Modeling of Impact of Green-Oriented Transportation Planning and Management Measures on the Economic Development of Small- and Medium-Sized Cities by Yuan Lu, Jinyan Shao, Yifeng Yao

“…With the rapid growth of urbanization and motorization in China in recent years, the demand for transportation in people’s work and daily lives has increased. In this context, a number of issues such as urban traffic congestion, energy consumption, and environmental pollution have become increasingly severe. …”
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Cell Therapy in Ischemic Heart Disease: Interventions That Modulate Cardiac Regeneration by Maximiliano I. Schaun, Bruna Eibel, Melissa Kristocheck, Grasiele Sausen, Luana Machado, Andreia Koche, Melissa M. Markoski

“…This review brings together current data on pharmacological and nonpharmacological approaches to improve cell homing and cardiac repair.…”
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Good quality of life in former Buruli ulcer patients with small lesions: long-term follow-up of the BURULICO trial. by Sandor Klis, Adelita Ranchor, Richard O Phillips, Kabiru M Abass, Wilson Tuah, Susanne Loth, Kristien Velding, Tjip S van der Werf, Ymkje Stienstra

“…However, recent advances in treatment, combined with increased public health efforts have the potential to significantly improve disease outcome.…”
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Transformation of the Regional Policy of Russia and China under the Conditions of Unequal Development of Regions (1980-2020): a Comparative Historical Study by S. B. Makeeva

“…The purpose of this article is a comparative and consideration of the evolution of the regional policy of Russia and China in the context of the increasing unevenness and disproportionality of the internal regional development of the two countries in the modern period of history. …”
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The PRE‐registration podiatry: Accessible recruitment and employment (PREPARE) project: A commentary on the novel approach to the podiatry workforce crisis in Glasgow by Pamela Price, Paul Higgins, David Lambert, Diane M. Dickson, Ruth Barn

“…This paper explores the local context of the current workforce challenges and summarises a novel solution collaboratively developed in Glasgow. …”
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Mitochondrial Reactive Oxygen Species Dysregulation in Heart Failure with Preserved Ejection Fraction: A Fraction of the Whole by Caroline Silveira Martinez, Ancheng Zheng, Qingzhong Xiao

“…In this review, we will provide an overview and discussion of the recent findings on mtROS production, its threshold for imbalance, and the subsequent dysfunction that leads to related cardiac and systemic phenotypes in the context of HFpEF. We will also focus on newly discovered cellular and molecular mechanisms underlying ROS dysregulation, current therapeutic options, and future perspectives for treating HFpEF by targeting mtROS and the associated signal molecules.…”
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Evidence of traditional Chinese medicine for treating type 2 diabetes mellitus: from molecular mechanisms to clinical efficacy by Yadong Ni, Xianglong Wu, Wenhui Yao, Yuna Zhang, Jie Chen, Xuansheng Ding

“…Context The global prevalence of type 2 diabetes mellitus (T2DM) has increased significantly in recent decades. …”
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Exploring the Acceptance and Opportunities of Using a Specific Generative AI Chatbot to Assist Parents in Managing Pediatric Rheumatological Chronic Health Conditions: Mixed Method... by Cheryl W Y Lau, Klaudia Kupiec, Polly Livermore

“…Understanding how we can support families better, without the need for increased personnel, will have implications for the health care systems. …”
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Good governance as the basis for the successful implementation of Ukraine’s state policy on European integration by O.V. Orel

“…To foster the development of Ukraine’s public administration in the context of European integration processes, this article substantiates and proposes the creation of a state policy document entitled «White Paper: Public Administration in Ukraine», structured as follows: Achievements (a brief overview of public administration reform outcomes in Ukraine); Benchmarks (description of good governance principles as key reform guidelines); Current State (description of the state of public administration in Ukraine at the time of research); Problems (overview of key issues, including an assessment of the compliance of public administration in Ukraine with good governance principles); Rationale for Reform (arguments in favour of further public administration reforms in Ukraine); Goals and Methodology (identification of the main purpose, goals, tasks, and applied research methods); Research Analysis (overview of the findings from major contemporary scientific and practical studies in the field of public administration in Ukraine and worldwide); Directions and Means of Reform Implementation (description of vectors for the future development of public administration in Ukraine and proposals for implementing core and alternative decisions); Results (description of intended outcomes, risks, and threats related to their achievement); Conclusions (logical summary of the material presented); Bibliography; Appendices. …”
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