miR-34a-5p modulation of polycystic ovary syndrome via targeting the NOTCH signaling pathway by Kexin Zhang, Xiaomeng Wang, Fang Liu, Hong Lin, Yan Wang, Min Zhao, Xiaofei Wang, Yijing Chu, Lin Xu

“…Abstract Purpose Polycystic ovary syndrome (PCOS) is currently recognized as a condition that affects several systems in the body, including the reproductive, endocrine, and cardiovascular systems. …”
Get full text

Oxidation behaviour of Ti-V-Cr-Nb-Ta and Al-Ti-V-Cr-Ta refractory high entropy alloys: Effects of Nb and Al substitutions by Kieran Rivers, Bradley Young, Yuanbo T. Tang, Bo-Shiuan Li, Angus J. Wilkinson, David E.J. Armstrong, Junliang Liu

“…However, a significant issue with current RHEAs is that those exhibiting good mechanical properties tend to show poor oxidation resistance, and vice versa. …”
Get full text

Impact of Metal Source Structure on the Electrocatalytic Properties of Polyacrylonitrile-Derived Co-N-Doped Oxygen Reduction Reaction Catalysts by Arseniy Kalnin, Ksenia Kharisova, Daniil Lukyanov, Sofia Filippova, Ruopeng Li, Peixia Yang, Oleg Levin, Elena Alekseeva

“…We have proposed a multifunctional active metal source strategy based on the cobalt complex with the ligand containing pyridine and azo-fragments. This complex simultaneously provides the nitrogenous environment for the Co atoms and acts as a blowing agent due to N₂ extrusion, thus increasing the surface area and porosity of the material. …”
Get full text

Novel Nanotechnology of TiO2 Improves Physical-Chemical and Biological Properties of Glass Ionomer Cement by Daniela Dellosso Cibim, Miki Taketomi Saito, Priscila Alves Giovani, Ana Flávia Sanches Borges, Vanessa Gallego Arias Pecorari, Orisson Ponce Gomes, Paulo Noronha Lisboa-Filho, Francisco Humberto Nociti-Junior, Regina Maria Puppin-Rontani, Kamila Rosamilia Kantovitz

“…Furthermore, regardless of TiO2 concentration, no significant effect was found on SR, whereas GIC-containing 7% TiO2 presented decreased SH values. Fluoride release lasted longer for the 5% and 7% TiO2 groups, and cell morphology/spreading and ECM composition were found to be positively affected by TiO2 at 5%. …”
Get full text

Research progress in intracranial artery dissections over past 25 years: a review and bibliometric analysis by Zixuan Zhou, Zixuan Zhou, Zixuan Zhou, Bingyang Qin, Yang Chen, Yang Chen, Yang Chen, Ren Li, Ren Li, Ren Li, Biao Yang, Biao Yang, Biao Yang, Ziao Li, Ziao Li, Ziao Li, Yongqiang Wu, Yongqiang Wu, Yongqiang Wu, Xiaogang Wang, Xiaogang Wang, Xiaogang Wang, Xiaolong Guo, Xiaolong Guo, Xiaolong Guo, Wenju Zhang, Wenju Zhang, Wenju Zhang, Yuanli Zhao, Geng Guo, Geng Guo, Geng Guo, Geng Guo, Geng Guo

“…Keyword analysis of the literature showed that “recanalization “reached the highest intensity of outbreaks, while “thrombectomy “,” outcome “, “risk “, and “diagnosis “showed an increase in citations in 2025, indicating that these subjects continue to be of significant interest.ConclusionThis study explores the evolving research trends and challenges in the area of IAD, presenting a thorough examination of both its historical and current research contexts. …”
Get full text

Recent process in organic near-infrared fluorescent probes for detecting hypochlorous acid/hypochlorite by Zhongchang Wang, Chenzheng Guan, Wenxu Lu, Liangchao Yuan, Man Chao, Hai-Liang Zhu, Tingwu Liu

“…Finally, we outline future prospects, aiming to inspire innovative designs that will overcome current bottlenecks and propel the field towards clinical translation. …”
Get full text

Cybersecurity requirements for medical devices in the EU and US - A comparison and gap analysis of the MDCG 2019–16 and FDA premarket cybersecurity guidance by Max Ostermann, Rebecca Mathias, Fatemeh Jahed, Mitchell B. Parker, Florence D. Hudson, William C. Harding, Stephen Gilbert, Oscar Freyer

“…The increasing use of connected medical devices has led to substantial cybersecurity challenges, putting patient safety and the integrity of healthcare infrastructures at risk. …”
Get full text

The role of Pakistan Medical & Dental Council in steering undergraduate medical curriculum reforms in Pakistan by Gohar Wajid, Lubna Baig, Syeda Kauser Ali, Usman Mahboob, Ahsan Sethi, Rehan Ahmed Khan

“…There has been an exponential increase in the number of medical colleges in Pakistan over the past few decades, especially in the private sector. …”
Get full text

The Chem-Sex Inventory Scale (CSI): A Tool to Assess the Mental Health Risk of Chemsex Behaviors in Men Who Have Sex with Men by Pablo Del Pozo-Herce, Enrique Baca-García, Antonio Martínez-Sabater, Rubén Pérez-Elvira, Vicente Gea-Caballero, Elena Chover-Sierra, Pedro José Satústegui-Dordá, Alberto Tovar-Reinoso, Francisco José Rodríguez-Velasco, Mercedes Sánchez-Barba, Jesús Pérez, Raúl Juárez-Vela

“…Drugs associated with chemsex can trigger mental health problems such as anxiety, depression, risk of psychosis and suicidal ideation, social isolation, stigmatization, and even loss of impulse control and lack of coping strategies. Currently, the increase in illicit drugs in a sexual context is considered an outbreak of a public health emergency. …”
Get full text

Performance Characteristics of a Pilot-Scale Electromethanogenic Reactor Treating Brewery Wastewater by Kyle Bowman, Marcelo Elaiuy, George Fudge, Harvey Rutland, William Gambier, Theo Hembury, Ben Jobling-Purser, Thomas Fudge, Izzet Kale, Godfrey Kyazze

“…This investigation presents a 4-fold increase in size compared to the next largest pilot-scale MEC-AD system presented in the literature, providing findings to inform the operation of a 52,000 L MEC-AD system (currently under construction). …”
Get full text

Graded Roll‐to‐Roll Slot Die Coating for High‐Throughput Catalyst Layer Studies by George Pätzold, Maximilian Maier, Lukas Löttert, Anna T. S. Freiberg, Prof. Dr. Simon Thiele, Dr. Dominik Dworschak

“…Many of these systems are based on substrates coated with thin layers containing catalyst, ionomer or support material like carbon. …”
Get full text

A New Source of Inoculum for <i>Stemphylium vesicarium</i>: Consequences for the Management of Brown Spot of Pear by Federico Cavina, Serena Baiocco, Lorenzo Tomba, Fabio Ravaglia, Christian Moretti, Rosario Raso, Valentino Giorgio Rettore, Martina Parrilli, Gianfranco Pradolesi, Riccardo Bugiani

“…Brown spot of pear (BSP), caused by <i>Stemphylium vesicarium</i>, is one of the most dangerous pear fungal diseases, being responsible for huge losses in production. Currently, in order to increase its containment, chemical control is implemented in conjunction with agronomic techniques able to reduce BSP inoculum sources (e.g., orchard grass sanitation, litter removal or application of biocontrol agents). …”
Get full text

Specimens and culture media for the laboratory diagnosis of typhoid fever by John Wain, To Song Diep, Phan Van Be Bay, Amanda L. Walsh, Ha Vinh, Nguyen M. Duong, Vo Anh Ho, Tran T. Hien, Jeremy Farrar, Nicholas J. White, Christopher M. Parry, Nicholas P. J. Day

“…For 263 positive stool cultures, selenite F and selenite mannitol performed equally well and culturing 2 g rather than 1g increased the isolation rate by 10.5%. Conclusions: For the diagnosis of typhoid fever by blood culture the medium should be a rich nutrient broth containing a lysing agent. …”
Get full text

Understanding How, Why and for Whom Link Work Interventions Promote Access in Community Healthcare Settings in the United Kingdom: A Realist Review by Rebecca Golby, Fiona Lobban, Louise Laverty, Kyriakos Velemis, Vishal R. Aggarwal, Katherine Berry, Abby Morris, Emma Elliott, Rebecca Harris, Al Ross, Carolyn A. Chew‐Graham, Miranda Budd, Linda McGowan, David Shiers, Neil Caton, Chris Lodge, Paul French, Robert Griffiths, Jasper Palmier‐Claus

“…Conclusion Although link work interventions are increasingly utilised across community healthcare settings, the contexts in which they operate vary considerably, triggering a range of mechanisms. …”
Get full text

Role of tertiary lymphoid structures and B cells in clinical immunotherapy of gastric cancer by Weiyi Chen, Lingli Zhang, Man Gao, Ning Zhang, Rumeng Wang, Yang Liu, Yan Niu, Lizhou Jia, Lizhou Jia

“…Mature TLSs are B-cell regions containing germinal centers. During germinal center formation, B cells undergo transformations to become mature cells with immune function, exerting anti-tumor effects. …”
Get full text

Fatty fried food toxins as triggering stimuli to immune system interplay in global autoimmune diseases: A systematic review by Saba Anwar, Qamar Abbas Syed, Mahnoor Saleh, Muhammad Saad Akram, Ghayyor Sultan, Sahar Khalid, Anum Ishaq, Gholamreza Abdi, Rana Muhammad Aadil

“…The purpose of the current systematic review was to respond to the following query: Does the rising level of fatty fried food consumption trigger the major autoimmune diseases such as Crohn's disease, ulcerative colitis, rheumatoid arthritis, systemic lupus erythematous, and multiple sclerosis? …”
Get full text

Effect of hybrid reinforcements of TiO₂, Al₂O₃, and CNTs on superior mechanical and microstructural properties in epoxy/carbon fiber composite by N. Elzayady, Walid Mahmoud Shewakh, Mohamed Abu-Okail, H.T. Elmetwaly, A.M.I. Abu-Oqail

“…The current study focuses on multi-scale dual-hybrid composites. …”
Get full text

Optimizing nitrogen removal in advanced wastewater treatment using biological aerated filters by Juan Li, Juan Li, Ziru Niu, Ziru Niu, Lei Li, Shuting Zhou

“…In order to address this issue, the current study employed a biological aerated filter for the treatment of wastewater containing low nitrogen concentrations. …”
Get full text

Comprehensive Review of Intrusion Detection Techniques: ML and DL in Different Networks by Imane Rakine, Aziz Oukaira, Kamal El Guemmat, Issam Atouf, Sara Ouahabi, Mohamed Talea, Tarik Bouragba

“…With the increasing number of new attacks, virtualized and distributed networks require greater attention and investment in cybersecurity. …”
Get full text

Natural and Waste Materials for Desulfurization of Gaseous Fuels and Petroleum Products by Iliya Iliev, Antonina Filimonova, Andrey Chichirov, Alena Vlasova, Ruzina Kamalieva, Ivan Beloev

“…Natural gas, refinery gas, and coal gas contain acid gases such as hydrogen sulfide and carbon dioxide. …”
Get full text