Anti-tumor efficacy and safety of AEV01 in preclinical glioblastoma and hepatocellular carcinoma models by Indrani Biswas, Senthilathiban Daisy Precilla, Aravinda Kumar, M. M. Sekhar, Renu Medasani, T. S. Anitha

“…AEV01, a specialized lipophilic extract derived from the roots of Picrorhiza kurroa, has shown promise as a potential anti-cancer agent. In this context, the current study aimed to evaluate the anti-tumor efficacy and safety profile of AEV01 both in vitro and in vivo in GB and HCC models. …”
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Crosstalk between ferroptosis and innate immune in diabetic kidney disease: mechanisms and therapeutic implications by Jinyang Wang, Haonan Shi, Ye Yang, Xueli Gong

“…This review presents an overview of ferroptosis within the context of DKD, beginning with its core mechanisms and delving into its potential roles in DKD progression. …”
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Protective graphene oxide layers for enhanced stability of copper cathodes in zinc-ion energy storage systems by Nikos Κavousanos, Ricardo Santamaría Ramirez, Athanasia Kostopoulou, Konstantinos Brintakis, Emmanuel Stratakis, Dimitra Vernardou

“…However, this enhancement led in a slight initial drop in capacitance, attributed to the increased resistance of Zn+2 interactions with the cathode.…”
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Effectiveness of Nursing Intervention Protocol on Nurses’ Performance and Patients’ Self-Care after Cataract Surgery by Amal S. Taha

“… Context: Cataract is the leading cause of poor vision worldwide. …”
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Blood-based biomarkers in mild behavioral impairment: an updated overview by Efthalia Angelopoulou, Xenia Androni, Chiara Villa, Alexandros Hatzimanolis, Nikolaos Scarmeas, Sokratis Papageorgiou

“…A growing number of studies have recently begun to explore the relationship between MBI and several blood-based biomarkers associated with Alzheimer’s disease (AD) pathology, neurodegeneration, as well as systemic metabolic and inflammatory dysregulation. In this context, MBI has been associated with lower plasma Aβ42/Αβ40 ratio, higher plasma phosphorylated tau at threonine 181 (p-tau181), increased neurofilament light chain (NfL) levels, as well as disturbances in metabolic markers, including homocysteine, insulin and ferritin, suggesting a multifaceted neurobiological basis for this syndrome. …”
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The Role of Extracellular Vesicles in Aging and Age-Related Disorders by Bharathi Hassan Ganesh, Himabindu Padinjarathil, Ramya Lakshmi Rajendran, Prasanna Ramani, Prakash Gangadaran, Byeong-Cheol Ahn

“…Mitochondrial malfunction and increased oxidative stress are major contributors for the aging process. …”
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Assessment of Health-Oriented Layout and Perceived Density in High-Density Public Residential Areas: A Case Study of Shenzhen by Guangxun Cui, Menghan Wang, Yue Fan, Fei Xue, Huanhui Chen

“…The authors attempt to go beyond current regulations to propose tailored solutions for Shenzhen’s high-density context, improving spatial efficiency and residential comfort in future public housing designs. …”
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Objects of forensic documentary science by V. S. Sezonov

“…The scientific novelty lies in the establishment of promising areas for the development of an innovative methodology for conducting forensic document examination in the context of the use of special technical means and the methodology for the use of modern software products. …”
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Crop simulation models as decision tools to enhance agricultural system productivity and sustainability – a critical review by Koushik Banerjee, Suman Dutta, Sumanta Das, Rahul Sadhukhan

“…Feeding the growing global population necessitates increased agricultural production, yet agriculture remains a vulnerable sector facing significant challenges from limited land resources, environment, and climatic constraints. …”
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Overcoming immunosuppression in cancer: how ketogenic diets boost immune checkpoint blockade by Victoria E. Stefan, Daniela D. Weber, Roland Lang, Barbara Kofler

“…., high-fat low-carbohydrate diets, have been shown to have antiproliferative and immunomodulatory effects in various preclinical cancer studies. Here, we review current knowledge of the complex interplay of KDs and the anti-tumor immune response in the context of ICB therapy, to update our understanding of diet-induced immunometabolic reprogramming in cancer. …”
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The frequent variant A57F in the GNE gene in patients from Russia has Finno-Ugric Mari origin by Dmitrii Subbotin, Sofya Ionova, Andrey Marakhonov, Elena Saifullina, Artem Borovikov, Leila Akhmadeeva, Polina Chausova, Oksana Ryzhkova, Rena Zinchenko, Sergey Kutsev, Aysylu Murtazina

“…According to our study, the estimated age of the mutation’s spread is 160.46 years (95% CI: 45.55–244.14).DiscussionBy comparing the information gathered with historical data on migration patterns in the Middle Volga region and estimating the age of the variant’s dissemination, we propose hypotheses regarding its origin and the pathways through which it spread. In the current context of increased rate of interethnic marriages, investigating the spread of common pathogenic variants from historically isolated populations is important for molecular genetic diagnosis. …”
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Horticultural performance and QTL mapping of snap bean (Phaseolus vulgaris L.) populations with organic and conventional breeding histories by Hayley E. P. Richardson, Ryan M. King, Joel Davis, James R. Myers

“…IntroductionImproving crop cultivars for use on organic farms is pertinent, as current elite germplasm is less resilient within the more variable context of organic farm environments. …”
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Transparent Assessment of the Supervision Information in China’s Food Safety: A Fuzzy-ANP Comprehensive Evaluation Method by Tingqiang Chen, Lei Wang, Jining Wang

“…The information transparency in the entirety presents deficiencies and gradually declines when that in the administrative level decreases. The economic development level indirectly determines the transparency level, and the transparency level does not conform to China’s current economic development level.…”
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Impact of demographic ageing on sustainability of public finance in Serbia by Zdravković Aleksandar, Domazet Ivana, Nikitović Vladimir

“…In this context, critical review of the current government approach to the pension growth dynamics was given from the perspective of medium-term sustainability of pension system, which resulted in appropriate recommendations. …”
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The Land Acquisition and Resettlement Frameworks for Irrigation Sector in the SADC Region: Strengths and Bottlenecks by devie Chilonga

“…This will still be a challenge with rapid population increases which are exerting pressure on land and the human rights watches actively operating in this sector, unless policies and legislation are responsive to current demands. …”
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Surface modification of aluminum on a silicon chip by citric acid treatment by Moataz Mekawy, Kazuya Iida, Akitsu Shigetou, Jin Kawakita

“…In situ electrical current measurements from arrays of aluminum wires located on the silicon chip were performed during the treatment. …”
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Homoseksual menurut Thanthawi Jauhari dalam Kitab al-Jawahir fi Tafsir Al-Qur`an al-Karim by Nurul Delfira Febriani, Risman Bustamam

“…Psychologically, sexual deviant behavior will result in the perpetrator experiencing a decrease in their ability to think.…”
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Japanese Model of Attracting Foreign Youth in the Higher Education System by S. V. Ryazantsev, T. K. Rostovskaya, N. S. Ryazantsev

“…National education and science systems are increasingly integrated into the international scientific and educational space in the context of increasing globalisation. …”
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Changing or validating physician opioid prescribing behaviors through audit and feedback and academic detailing interventions in primary care by Celia Laur, Natasha Kithulegoda, Nicola McCleary, Emily Nicholas Angl, Michael Strange, Barbara Sklar, Thivja Sribaskaran, Gail Dobell, Sharon Gushue, Jonathan M. C. Lam, Lindsay Bevan, Victoria Burton, Lena Salach, Justin Presseau, Laura Desveaux, Noah Ivers

“…Physicians mentioned that academic detailing validated current opioid practices or increased their belief about capabilities and their intentions , mediated by increased skills and the impact of environmental context and resources . …”
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Formation of the Soviet education system among the indigenous peoples of Southern Siberia in the 1920s by L. N. Aksenova, L. V. Sokolskaya, A. S. Valentonis, I. V. Shcherbinina

“…Today, the interest of researchers in regional history has increased all over the world; therefore, the current article will be useful to readers, as the analysis of new archival documents helps to fill the gaps in the scientific literature on the establishment of the Soviet school among the indigenous peoples of southern Siberia in the 1920s. …”
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