HNF-1β alleviates podocyte injury in lupus nephritis by maintaining endoplasmic reticulum homeostasis by Jie Yu, Bing Guo, Fan Zhang, Miao Liu, Ying Xie, Hui-mei Zou, Yuan-yuan Ruan, Xiao-min An, Pei-lei Chen, Ying-qin Luo, Ming-jun Shi, Li-fen Xu

“…Dual-luciferase reporter assays and chromatin immunoprecipitation (ChIP) assays were performed to investigate the transcriptional activation of Derlin-1 and VCP promoters by HNF1-β.Results A significant decrease in HNF1-β levels was observed in kidney tissues from patients with LN while MRL/lpr mice exhibited an initial compensatory increase followed by a subsequent decrease in renal HNF1-β expression. …”
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ECONOMIC CRISIS AND THE COMPETITIVENESS OF TRANSNATIONAL COMPANIES by LIVIU RADU, CARMEN RADU

“…In crisis situations, the competitiveness of transnational companies becomes a particularly complex concept, due to the fact that said business entities are continuously moving within the context of internationalization and increasing use of global strategies. …”
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A problem of budget rigidities in the state budget and the evolving environment of Polish public finances by Michał Ostrowski

“…On the basis of the current processes taking place in the fiscal policy, the author indicates the need to consider the described problem in a wider context.…”
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Influence of Silicon NanoSheet (SiNS) on the toughness of Biphasic Calcium Phosphate (BCP) composites by Anwer AL-Obaidi, Hussein K. Dalfi, Nazar Abdulridha, Amer Alomarah

“…This increase gave sufficient motivation to adopt this composition and addition in biomedical applications.…”
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The Quest to Re-energise Academic Staff in Higher Education in an Age of Performativity by Ioanna Palaiologou, Stephen Burwood, Thomas Feldges, Trevor Male

“…This article explores how it may be possible to re-energise academic staff within the current context of expectations of managers within higher education (HE) in England. …”
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Outcomes of COVID-19 on Patients with Cancer: A Scoping Review by Amjad Alrehaili, Samah Sofar, Duha Wazqar

“… Context: The COVID-19 pandemic has resulted in an unprecedented global health crisis. …”
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COVID-19 and Inflammatory Bowel Diseases: Risk Assessment, Shared Molecular Pathways, and Therapeutic Challenges by Iolanda Valentina Popa, Mircea Diculescu, Cătălina Mihai, Cristina Cijevschi-Prelipcean, Alexandru Burlacu

“…Conclusions. Using the current understanding of SARS-CoV-2 as well as other pathogenic coronaviruses immunopathology, we showed why IBD patients should not be considered at an increased risk of infection or more severe outcomes. …”
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Selection of Prosthesis in Aortic Valve Surgery: Short Review and Trend in our Practice in 10 Years by Selman Dumani, Ermal Likaj, Laureta Dibra, Devis Pellumbi, Adelina Musliu, Fjoralba Qejvani, Altin Veshti

“…This paper presents current issues regarding selecting aortic valve prostheses, considering factors related to the prosthesis and the patient. …”
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Fishing, offshore wind energy, climate change and marine spatial planning: Is it possible to plan for a best use of space? by Neda Trifonova, Beth E. Scott, Stephen C. L. Watson, Claire Szostek, Morgane Declerck, Nicola Beaumont

“…This perspective provides a methodology roadmap that considers the link between, and the need for, both food and energy security from our oceans and provides a route to increased certainty in our current choices for the long‐term sustainable use of our oceans.…”
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The Silent Burden of De Novo Metastatic Prostate Cancer in the Middle East: A Call for Region-Specific Screening Guidelines by Noura Abbas, Laudy Chehade, Zahi Abdul Sater, Ali Shamseddine

“…<b>Methods</b>: We conducted a comprehensive narrative review of epidemiological data on prostate cancer in the ME, examining trends in incidence and mortality, de novo metastatic cases, and current screening practices. Additionally, we assessed the applicability of international guidelines for prostate cancer screening to the ME context. …”
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Dopamine modulates persistent synaptic activity and enhances the signal-to-noise ratio in the prefrontal cortex. by Sven Kroener, L Judson Chandler, Paul E M Phillips, Jeremy K Seamans

“…When the background DA was eliminated by depleting DA with reserpine and alpha-methyl-p-tyrosine, or by preparing corticolimbic co-cultures without the VTA slice, Up-states could be enhanced by low concentrations (0.1-1 microM) of DA that had no effect in the VTA containing cultures. Finally, in spite of the concentration-dependent effects on Up-states, exogenous DA at all but the lowest concentrations increased intracellular current-pulse evoked firing in all cultures underlining the complexity of DA's effects in an active network.…”
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Malted Multi-millet based Probiotic Dairy Beverage: Nutritional, Sensory, Physicochemical and Microbiological Characterization by G. Swarnalatha, S. Sharath Kumar, T. V. Madhavi

“…The acidity and probiotic count were increased with increased rate of millet incorporation. …”
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The Axial Uplift Capacity of Screw Piles: A Review by Ibrahim W. Ibrahim, Mahdi Karkush

“…Finally, increasing the undrained shear strength of clayey soil and the relative density of sandy soil gave a higher uplift capacity. …”
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IoT Device Identification Techniques: A Comparative Analysis for Security Practitioners by Ashley Andrews, George Oikonomou, Simon Armour, Paul Thomas, Thomas Cattermole

“…We then produce a summary table containing just the information for the five elements for each study, and how they can be used to understand and compare techniques, considering their context. …”
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Policies and guidelines supporting the sustainability of human milk donation to milk banks in Switzerland: a document analysis by Christelle Kaech, Tracy Humphrey, Catherine Kilgour, Céline Julie Fischer Fumeaux, Claire de Labrusse

“…Globally, despite an increasing number of human milk banks, the demand for donor milk exceeds the supply, and access remains inequitable and insufficient. …”
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US Deterrence against Russia and China (based on strategic documents of J. Biden administration) by V. I. Batyuk

“…A closer examination of key strategic documents published in recent years shows that if from a political and military point of view, the US strategists come up with a generally rational list of measures aimed at countering the challenge, posed by Russia and China, from an ideological point of view they doggedly follow liberal-hegemonic premises that are increasingly inconsistent with current international political realities. …”
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Brownian motion effects and thermophoresis on heat transmission mechanism of hybrid nano liquid flow over a stretched wedge surface by Sharanayya Swami, Suresh Biradar, Jagadish V Tawade, Vediyappan Govindan, Haewon Byeon, Busayamas Pimpunchat

“…The current study observes the impact of thermophoresis, Brownian motion, and magnetic fields on the flow and heat transfer properties of a hybrid nanofluid containing Al2O3, CuO, and ethylene glycol over a wedge-shaped surface undergoing horizontal stretching. …”
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Transformation of the organization’s management in the digital economy by E. I. Lugovskoy

“…The issues of qualitative transformation of management systems in the context of digitalization and its impact on the improvement of business process technologies are of particular relevance. …”
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A broad-spectrum pneumococcal vaccine induces mucosal immunity and protects against lethal Streptococcus pneumoniae challenge by Fang-Feng Chiu, Ling-Ling Tu, Wangxue Chen, Hongyan Zhou, Bing-Sin Liu, Shih-Jen Liu, Chih-Hsiang Leng

“…Consistently, LAAC immunization increased the survival rate of mice after bacterial challenge with both PCV13 and non-PCV13 serotypes. …”
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Classifying social position with social media behavioral data by Júlia Koltai, Zsófia Rakovics, Zoltán Kmetty, Kata Számel, Borbála Ungvári, Bendegúz Váradi, Ákos Huszár

“…When analyzing digital behavioral data, however large scale it is, information on the social position of the users is hardly available. In the current paper, we analyze a special dataset collected with a data donation technique, which contains information on both the social position and the observed digital behavior of participants, and which is representative for the internet user population of Hungary. …”
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