NMDA Receptor–Mediated Ca2+ Flux Attenuated by the NMDA Receptor/TRPM4 Interface Inhibitor Brophenexin by Jordan Casby, Benjamin M. Gansemer, Stanley A. Thayer

“…Incubating cultures in Mg2+‐free buffer containing tetrodotoxin, 6‐cyano‐7‐nitroquinoxaline‐2,3‐dione, and bicuculline for 30 min inhibited NMDA‐evoked increases in intracellular Ca2+ concentration ([Ca2+]i) recorded at 22°C by 50% ± 18% and prevented inhibition by brophenexin. …”
Get full text

Data stewardship and curation practices in AI-based genomics and automated microscopy image analysis for high-throughput screening studies: promoting robust and ethical AI applicat... by Asefa Adimasu Taddese, Assefa Chekole Addis, Bjorn T. Tam

“…Abstract Background Researchers have increasingly adopted AI and next-generation sequencing (NGS), revolutionizing genomics and high-throughput screening (HTS), and transforming our understanding of cellular processes and disease mechanisms. …”
Get full text

Urban Regeneration for the Resilient City: Implementation of Sustainable Urban Drainage Solutions in Pisa's High Flash Flood Risk Areas by Luisa Santini, Greta Frosini, Cinelli Fabrizio

“…This research, funded by UNIPI PRA_2022_22, titled “Mitigating Risks in Urban Areas”, aims to develop a methodology to analyse and evaluate the benefits of increased resilience in urban contexts following the implementation of NBS. …”
Get full text

Optimal Decision-Making in a Green Supply Chain Duopoly: A Comparative Analysis of Subsidy Strategies with Data-Driven Marketing by Yao Yao, Shaoqing Geng, Jianhui Chen, Feng Shen, Huajun Tang

“…In the current context of severe environmental challenges and climate change, the low-carbon green development model has become an international consensus. …”
Get full text

Rehabilitation interventions delivered via telehealth to support self-management of rheumatic and musculoskeletal diseases: A scoping review protocol. by Rosemarie Barnett, Nuzhat Shakaib, Thomas A Ingram, Simon Jones, Raj Sengupta, Peter C Rouse

“…Data will be summarized qualitatively, and if appropriate, quantitatively via frequency counts of the components comprising the 'Concept' and 'Context' categories of the PCC framework.<h4>Discussion</h4>Findings from the proposed scoping review will identify how telehealth is currently used in the delivery of rehabilitation interventions for RMDs. …”
Get full text

Characterization of imogolite-type nanoparticles in Podzols: morphology and association with iron by Tove Florén, Manuel Bartolomé Díaz, Geert Cornelis, Stephen Hillier, Jon Petter Gustafsson

“…The aim of this study was to assess the properties of ITN in soil, in order to increase the current knowledge of ITN regarding adsorption models. …”
Get full text

Invisible lives, visible challenges: The socio-environmental impacts of undocumented Afghan immigrants on the host society by K. Iqbal, H. Liang

“…ABSTRACTBACKGROUND AND OBJECTIVE:Today's illegal immigrant crisis in general and the illegal Afghan immigrant crisis, in particular, are considered a continuous challenge of the current century since the mass migration of people from their country of origin has exponentially increased. …”
Get full text

Internet of Things in healthcare: An adaptive ethical framework for IoT in digital health by Abubakar Wakili, Sara Bakkali

“…This paper contributes a novel, dynamic framework that encapsulates current ethical considerations and is designed to adapt to future technological evolutions, thereby fostering ethical resilience in the face of ongoing digital health innovation. …”
Get full text

Battle for “Donat”: а discussion about the old and new classical philology in Russia (1847–1848) by Kira Ilina

“…Hofman and his disciples considered it necessary for a classical philologist to know the current level of development of classical philology, as well as to appeal to modern philologists and to change the methods of teaching Latin. …”
Get full text

Human Perspectives and Social Infrastructures: Prioritising People in GLAM Digitisation by Megan Gooch, Rebecca Kahn, Edurne Kugeler

“…Much discussion in current digital humanities research and funding is concerned with creating, using and maintaining technical and research infrastructures. …”
Get full text

“It’s easy to be burned out in this line of work”: Experiences of burnout among Black women pelvic floor therapists in the United States by Shemeka Thorpe, Praise Iyiewuare, Brenice Duroseau, Natalie Malone, Kaylee A Palomino

“…Consequences of burnout included leaving the current work setting, a strong desire to transition to a different setting, or taking a break from the profession overall. …”
Get full text

Effects of step width and gait speed on the variability of mediolateral control in the head and trunk during gait. by Yu Takada, Tomoaki Atomi, Takayuki Yagi, Shoma Yamamoto, Masao Tomita, Miho Shimizu, Yoriko Atomi

“…It suggests that narrow step widths necessitate advanced control strategies, while wide step widths promote simpler, compensatory mechanisms, especially relevant in clinical contexts.…”
Get full text

Epigenetic regulation and memories: possible applications to grapevine in Uruguay by Mercedes Fourment, Philippe Gallusci

“…This article summarizes the current understanding of epigenetic regulation in grapevines, emphasising their significance in a clonally propagated plant with limited genetic diversity. …”
Get full text

Recommendations for Interventions to Improve Function in Patients With Lung Cancer: A Clinical Practice Guideline by Mary Vargo, Lynn H. Gerber, Laura S. Gilchrist, Mary Insana Fisher

“…Further study is needed into sustainability of performing the interventions and durability of outcomes; increased breadth of interventions and functional outcome domains examined; and exploration of specific contexts including advanced disease, survivorship, high medical complexity and frailty, and caregiver‐related factors. …”
Get full text

Investigating How Policies and Other Conditions Contribute to Influencing Agricultural GHG Emissions in the EU by Francesco Galioto, Irene Criscuoli, Andrea Martelli, Maria Valentina Lasorella, Ilaria Falconi, Danilo Marandola, Giovanni Dara Guccione, Francesca Varia

“…Based on these facts, we introduce the context of implementation of the 2014–2022 Common Agricultural Policy (CAP), within which many interventions were designed to improve sustainability and increase competitiveness, and we formulate hypotheses on how CAP instruments can contribute differently to influencing GHG emissions from agriculture. …”
Get full text

Molecular Characterization of Plasmid-Mediated Non-O157 Verotoxigenic Escherichia coli Isolated from Infants and Children with Diarrhea by Md Fazlul Karim Khan, Shah Samiur Rashid

“…A significant increase in the incidence of non-O157 verotoxigenic Escherichia coli (VTEC) infections have become a serious health issues, and this situation is worsening due to the dissemination of plasmid mediated multidrug-resistant microorganisms worldwide. …”
Get full text

Optimization of Physicochemical Parameters during the Electrocoagulation Cadmium Elimination by Abdelaaziz Aityoub, Abdesselam Abouelfida, Abdelaziz Benyaich, Abderrahmane Romane, Mohamed Elmeray, Rachid Idouhli, Yassine Koumya, Mohyeddine Khadiri

“…The increased use of fertilizers from phosphates in agriculture generates water pollution by heavy metals contained in these phosphates at levels higher than the standards. …”
Get full text

E-cigarette use and susceptibility among Indonesian youth: the role of social environment, social media, and individual factors by Mouhamad Bigwanto, Melinda Pénzes, Nurul Kodriati, Emma Rachmawati, Nida Amalia, Róbert Urbán

“…Boys were significantly more likely than girls to be current (OR = 6.67, 95% CI [3.05–14.57]) and ever e-cigarette users (OR = 2.92, 95% CI [2.10–4.06]). …”
Get full text

Comparison of Bone Mineral Density in Lumbar Spine and Fracture Rate among Eight Drugs in Treatments of Osteoporosis in Men: A Network Meta-Analysis. by Ling-Xiao Chen, Zhi-Rui Zhou, Yu-Lin Li, Guang-Zhi Ning, Tian-Song Zhang, Di Zhang, Shi-Qing Feng

“…<h4>Context</h4>The preferred treatment for osteoporosis in men is debated, and pairwise meta-analysis cannot obtain hierarchies of these treatments.…”
Get full text

Rebooting Master’s Programs in an Updated Higher Education System: Management Track by E. A. Kuklina

“…The article substantiates proposals that contribute to updating the Russian model of master’s training in the management track in the direction of increasing its efficiency, competitiveness and relevance.Research objectives: to consider the role of the master’s degree institute in the context of value creation by universities; justify one of the possible approaches to the design of a master’s program, which is based on the implementation of new principles for the creation and implementation of an educational product (using the example of direction 38.04.01 — Economics); consider the “double degree” format as part of a package proposal for the implementation of an MBA program and a master’s program (in the direction of 04/38/02 — Management); justify the need to include disciplines on venture financing and risk management of technological projects in the structure of the master’s training curriculum. …”
Get full text