Global Secular Trend of Gonadal Size in Men: Review and Analysis of Publications by A. Yu. Seroukhov, A. A. Afoko, I. E. Mamaev

“…Notwithstanding the general increase in world population, there is a steady decline in birth rate. …”
Get full text

Graded Roll‐to‐Roll Slot Die Coating for High‐Throughput Catalyst Layer Studies by George Pätzold, Maximilian Maier, Lukas Löttert, Anna T. S. Freiberg, Prof. Dr. Simon Thiele, Dr. Dominik Dworschak

“…Many of these systems are based on substrates coated with thin layers containing catalyst, ionomer or support material like carbon. …”
Get full text

Engineered extracellular vesicles for delivering functional Cas9/gRNA to eliminate hepatitis B virus cccDNA and integration by Wanjia Zeng, Liwei Zheng, Yukun Li, Jing Yang, Tianhao Mao, Jing Zhang, Yanna Liu, Jing Ning, Ting Zhang, Hongxin Huang, Xiangmei Chen, Fengmin Lu

“…Our results demonstrated that engineered EVs containing Cas9/gRNA and VSV-G can effectively reduce viral antigens and cccDNA levels in the HBV-replicating and infected cell models. …”
Get full text

Factor-H-related protein 1 (FHR1), a promotor of para-inflammation in age-related macular degeneration by Andjela Sekulic, Sarah M. Herr, Kelly Mulfaul, Inga-Marie Pompös, Silvia Winkler, Carola Dietrich, Benedikt Obermayer, Robert F. Mullins, Thomas Conrad, Peter F. Zipfel, Florian Sennlaub, Christine Skerka, Olaf Strauß

“…Polymorphisms in complement factor-H increase, while absence of factor-H-related protein-1 (FHR1) decreases the AMD risk, currently explained by their opposing relationship. …”
Get full text

Soil Decomposer Can Regulate the Legacy Effect of Photodegradation on Forest Marcescent Litter Decomposition, but Emerging Microplastics Disrupt This by Kai Tian, Xin Wang, Rumeng Ye, Yingqi Wang, Zhicheng Chen, Xiaojing Liu, Wenxia Wang, Lunguang Yao

“…ABSTRACT Photodegradation—photochemical mineralization of standing litters—often exerts a legacy effect aiding biodegradation in soil (PLE), which is overlooked in deciduous forests containing marcescent leaves. Meanwhile, increasing anthropogenic microplastics have deposited in forests, how they would affect the PLE on subsequent litter bio‐decomposition is currently unknown. …”
Get full text

Cytomegalovirus-Specific T Cells from Third-Party Donors Successfully Treated Refractory Cytomegalovirus Retinitis after Unrelated Umbilical Cord Blood Transplantation by Na Li, Guangyu Sun, Lihua Zhu, Kang Ding, Huilan Liu, Xiaoyu Zhu, Baolin Tang, Wen Yao, Xiang Wan, Liangquan Geng, Ping Qiang, Kaidi Song, Changcheng Zheng, Zimin Sun, Juan Tong

“…Umbilical cord blood (UCB) transplants (UCBTs) are becoming increasingly common in the treatment of a variety of hematologic and nonhematologic conditions. …”
Get full text

Evolution of taxis responses in virtual bacteria: non-adaptive dynamics. by Richard A Goldstein, Orkun S Soyer

“…We currently lack a full understanding of the different pathway structures and dynamics and how this integration is achieved. …”
Get full text

Spaciotemporal distribution characteristics of glacial lakes and the factors influencing the Southeast Tibetan Plateau from 1993 to 2023 by Yu Mingwei, Guo Yonggang, Zhang Jian, Li Feng, Su Libin, Qin Deshun

“…However, given the backdrop of a slight increase in precipitation and a gradual increase in temperature, the proliferation of glacial lakes is projected to accelerate predominantly in Nyingchi City’s eastern and western regions.…”
Get full text

Safety of a change of specifications of phytosterols/phytostanols as a novel food pursuant to Regulation (EU) 2015/2283 by EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Dominique Turck, Torsten Bohn, Montaña Cámara, Jacqueline Castenmiller, Stefaan De Henauw, Karen Ildico Hirsch‐Ernst, Ángeles Jos, Alexandre Maciuk, Inge Mangelsdorf, Breige McNulty, Androniki Naska, Kristina Pentieva, Alfonso Siani, Frank Thies, Margarita Aguilera‐Gómez, Francesco Cubadda, Thomas Frenzel, Marina Heinonen, Monika Neuhäuser‐Berthold, Helle Katrine Knutsen, Morten Poulsen, Miguel Prieto Maradona, Josef Rudolf Schlatter, Alexandros Siskos, Henk vanLoveren, Wolfgang Gelbmann, Harry J. McArdle

“…Regarding the maximum limit of the specification parameter ‘other sterols/stanols’, the applicant asks for an increase from currently less than 3% to less than 7% to better reflect and cover the natural composition and proportions of sunflower‐based phytosterols/phytostanols, noting that the existing specifications have been established largely based on the NF when sourced from soy. …”
Get full text

Optimizing enzyme thermostability by combining multiple mutations using protein language model by Jiahao Bian, Pan Tan, Ting Nie, Liang Hong, Guang‐Yu Yang

“…It showed a 10.19°C increase in the melting temperature and an ~655‐fold increase in the half‐life at 58°C. …”
Get full text

Ipomoea batatas (L.) Lam. cultivation in the conditions of light culture in vitro and ex vitro by E. A. Kalashnikova, R. N. Kirakosyan, A. V. Gushchin, K. G. Abubakarov, N. N. Sleptsov, S. K. Temirbekova, A. P. Glinushkin, O. V. Meleshina, N. Ya. Rebouh, M. M. Tareeva

“…Interest in this substance is justified by its valuable properties – it is a good immunomodulator, cleanses the body of toxins, radionuclides, "bad" cholesterol, promotes the assimilation of useful trace elements necessary for human life. Inulin is contained in plants such as jerusalem artichoke, chicory, as well as in sweet potatoes, the popularity of which is increasing every year. …”
Get full text

Clinical and laboratory assessment of the effect of hygiene products on the condition of periodontal tissues and hard tooth tissues in the treatment of caries by indirect method by I. A. Belenova, V. A. Mitronin, Z. A. Filippova, V. I. Khryachkov, M. S. Vasilyeva, N. A. Protsenko

“…According to statistics, the widespread use in modern dental practice of indirect restoration methods in the treatment of caries of the frontal group of teeth leads to an increase in the incidence of marginal periodontal disease. …”
Get full text

Multi-omics reveals total flavones from Abelmoschus manihot (L.) Medik. [Malvaceae] ameliorate MAFLD via PI3K/AKT/mTOR-mediated autophagy by Chao Lv, Chao Lv, Chao Lv, Chao Lv, Chao Lv, Lei Zhao, Jiani Hou, Hongyin Sun, Hongyin Sun, Hongyin Sun, Zhongsha Li, Zhongsha Li, Zhongsha Li, Zhongsha Li, Yuesong Wu, Yuesong Wu, Yuesong Wu, Yuesong Wu, Peizheng Shi, Yaping Xiao, Yunjin Xie, Yunjin Xie, Yunjin Xie, Yunjin Xie, Wei Su, Wei Su, Wei Su, Wei Su, Mingzhu Yin, Mingzhu Yin, Mingzhu Yin, Mingzhu Yin

“…In MAFLD mice, TFA treatment significantly decreased body weight gain, hepatic lipid accumulation, and the serum levels of ALT, AST, TC, and TG. …”
Get full text

Standardization of the Pharmaceutical Substance of the Drug LCS-1208 by E. V. Ignateva, I. V. Yartseva, Z. S. Shprakh, A. P. Bud'ko, L. V. Ektova, D. A. Kozin, V. Yu. Reshetnyak, O. V. Nesterova, E. A. Pankratova

“…Indolocarbazole derivatives are of increasing scientific interest for practical oncology. …”
Get full text

Optimizing Deep Learning Models with Improved BWO for TEC Prediction by Yi Chen, Haijun Liu, Weifeng Shan, Yuan Yao, Lili Xing, Haoran Wang, Kunpeng Zhang

“…Recently, deep learning models have become increasingly popular in TEC prediction. However, these deep learning models usually contain a large number of hyperparameters. …”
Get full text

Ecotoxicological effects of soft plastic fishing lures on the benthic amphipod Hyalella azteca by Beggel S, Kalis EJJ, Gilb KM, Pander J, Geist J

“…Especially soft plastic lures are increasingly used, potentially contributing to the pollution of waterbodies by the release of hazardous substances such as plasticizers. …”
Get full text

Anatomical theatre or full digitisation? Students’ preferences in field of anatomy teaching by Krzysztof Starszak, Radosław Karaś, Andrzej Skalski, Karolina Czarnecka-Chrebelska, Tomasz Lepich, Grzegorz Bajor

“…BACKGROUND: For many years, the teaching of anatomy has been based on traditional forms of imparting knowledge, but innovative solutions are currently being implemented on a large scale around the world. …”
Get full text

Twin Rooms – new experimental test cells for testing advanced facade elements by Boris Bielek, Daniel Szabó, Josip Klem, Kristína Kaniková, Alžbeta Danková

“…Reducing the energy intensity of buildings will increasingly resonate in individual political and professional circles. …”
Get full text

Federated learning with tensor networks: a quantum AI framework for healthcare by Amandeep Singh Bhatia, David E Bernal Neira

“…In this work, we propose a federated learning framework based on quantum tensor networks (QTNs) that takes advantage of the principles of many-body quantum physics. Currently, there are no known classical tensor networks (TNs) implemented in federated settings. …”
Get full text

PANCAKE: A Python-based Numerical Color–Magnitude Diagram Analysis Package by Yun Zheng, Yujiao Yang, Yong-Kun Zhang, Zheng Zheng, Jing Wang, Lister Staveley-Smith, Chao-Wei Tsai, Di Li, Chao Liu, Jingjing Hu, Huaxi Chen, Donghui Quan, Yinghui Zheng, Hangyuan Li

“…The color–magnitude diagram (CMD) stands out as the most accurate tool currently available for inferring the star formation histories (SFHs) of nearby galaxies with stellar-resolved multiband data. …”
Get full text