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1441
Novel Hypericin-loaded nanoparticles as a new drug delivery system ameliorate olanzapine-induced early renal injury and oxidative stress: In vitro and in vivo approaches
Published 2025-05-01“…The HP-SiNPs release profile, entrapment efficiency, cytotoxicity against the Vero cell line, renal function parameters, antioxidant efficacy, and histological changes in male rats administered with OLZ were all investigated, and they were compared to those of free HP.XRD reveals the development of an HP-silica-based composite with a 275.0 nm particle size, which increases BET surface area and thermal stability. An entrapment efficiency of around 95.61 ± 0.28 %, and a prolonged release of less than 20 % after 12 h were validated by the current results. …”
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1442
Exposure to secondhand smoke from cigarettes and secondhand aerosol from tobacco and nicotine products in indoor and outdoor public spaces in the European Union: a cross-sectional...
Published 2025-07-01“…Introduction In December 2024, the Council of the European Union (EU) adopted a recommendation to expand regulations on the use of nicotine-containing products both in indoor settings and specific outdoor areas. …”
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1443
From waste to weapon: the potential of medicinal plant waste extracts for eco-friendly crop disease management
Published 2025-03-01“…The increasing challenge of managing crop diseases requires innovative and sustainable approaches. …”
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1444
Transition Effects in Bridge Structures and Their Possible Reduction Using Recycled Materials
Published 2024-12-01“…This article serves as a review of the current challenges in bridge engineering, specifically addressing the transition effect and the utilization of recycled materials. …”
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1445
Substance P- and Insulin-like Growth Factor 1-derived Tetrapeptides for Neurotrophic Keratopathy Related to Leprosy: A Clinical Trial
Published 2025-03-01“…Although leprosy is bacteriologically curable, there is currently no efficient treatment. Eye drops containing tetrapeptides, phenylalanine-glycine-leucine-methionine-amide (FGLM-NH2) and serine-serine-serine-arginine (SSSR), derived from substance P and insulin-like growth factor 1, are clinically efficacious in the treatment of corneal epithelial disorders caused by neurotrophic keratopathy. …”
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1446
Sustainable Machining Using Eco-Friendly Cutting Fluids: A Review
Published 2022-01-01“…The base fluids of eco-friendly cutting fluids should contain some vegetable oil. Due to their eco-friendly, thermal, and tribological qualities, these types of machining fluids are becoming increasingly popular among researchers throughout the world. …”
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1447
An Integrated Profiling of Liver Metabolome and Transcriptome of Pigs Fed Diets with Different Starch Sources
Published 2024-11-01“…However, current research on the effects of diets with different starch sources on animals at the extraintestinal level is still very limited. …”
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1448
Vaccination as a solution of the issue of resistance S. pneumoniae
Published 2021-05-01“…Majority (92%) of multiresistant meningeal strains are covered by current PCVs. An anonymous questionnaire showed pediatricians' insufficient awareness about current approaches to pneumococcal infection prevention, underestimation of IPD risks and complications, and the impact of vaccination on reducing AMR. …”
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1449
Circulating Cell-free Tumor Nucleic Acids in Gastric Cancer
Published 2018-09-01“…Circulating tumor nucleic acids (ctNAs) originate in a tumor and contain tumor-related genetic or epigenetic alterations. …”
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1450
Mapping the status of global taxonomic knowledge of Orthoptera (Arthropoda, Insecta)
Published 2025-05-01“…Our analyses show that the descriptions of currently valid species increased exponentially since the 19th century, with a temporary decline following World War II, while synonyms outpaced the number of valid species until the 1980s. …”
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1451
Absorbable hemostatic hydrogels comprising composites of sacrificial templates and honeycomb-like nanofibrous mats of chitosan
Published 2019-05-01“…The CDPE template enables the assembly of imprinted chitosan honeycomb-like monolithic mats, containing highly entangled nanofibers with diameters of 9.2 ± 3.7 nm, thereby achieving an increase in the surface area of chitosan to improve hemostatic efficiency. …”
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1452
The Potential of Plant Extracts Used in Cosmetic Product Applications—Antioxidants Delivery and Mechanism of Actions
Published 2024-11-01“…Natural ingredients have been used in skincare products for thousands of years. The current focus is on novel natural bioactivities that shield the skin from UV rays and free radicals, among other damaging elements, while enhancing skin health. …”
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1453
Output Characteristics of Graphene Field Effect Transistors
Published 2020-12-01“…To perform the simulation, a computational algorithm was developed and a program of numerical simulation using the Monte-Carlo method in three-dimensional space using the Poisson equation was compiled and debugged.The results of the studies show that the development of field-effect transistors using graphene layers can improve the output characteristics – to increase the output current and transconductance, as well as the limit frequency of semiconductor structures in high frequency ranges.…”
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1454
Advances in vaccine adjuvant development and future perspectives
Published 2025-12-01“…Despite the need for potent and safe vaccine adjuvants, currently, there are still very few adjuvants in licensed human vaccines. …”
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1455
A review of the foliar application of individual amino acids as biostimulants in plants
Published 2025-05-01“…This review summarises current knowledge on the effects of the foliar application of the 20 most common naturally occurring amino acids. …”
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1456
A Comparison of The Content Of The Azerbaijan Press in The Reza Shah Period and The First Four Year Rule Od Mohammad Reza Shah (1925-1945)
Published 2023-04-01“…No criticisms were found regarding the current situation of the country or the senior officials of the Pahlavi administration. …”
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1457
Preserving Innovation: Ensuring the Future of Today’s Scholarship
Published 2022-04-01“…Scholars are experimenting with increasingly diverse digital technologies to express their research in new ways. …”
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1458
Self-Determination as a Mediator Between Mindfulness and Perfectionism in Theory and Practice
Published 2025-07-01“…Ninety-three university students filled a questionnaire containing mindfulness, perfectionism and motivation measures. …”
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1459
Label-free determination of hemodynamic parameters in the microcirculaton with third harmonic generation microscopy.
Published 2014-01-01“…The cell free layer containing the glycocalyx was also visualized. Comparison of the current microscopic resolution with theoretical, diffraction limited resolution let us conclude that an about sixty-fold THG signal intensity increase may be possible with future improved optics, optimized for 1200-1300 nm excitation. …”
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1460
EFFECT OF MARINATION WITH PROTEOLYTIC ENZYMES ON QUALITY OF BEEF MUSCLE
Published 2012-03-01“…Application of different treatments aimed to influence the proteolytic activity as is the case of enzymatic tenderization of beef.Improving the meat tenderness with proteolytic enzymes is promising, but current legislation restricting the use of proteolytic enzymes from bacterial origin and recommended tenderizers salts containing papain, ficin and bromelain. …”
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