An open-label phase I comparator-controlled clinical trial to assess tolerability and pharmacokinetics of IHL-675 A a fixed dose combination of cannabidiol plus hydroxychloroquine... by George Williams Mbogo, Pia Kroner, Rosemarie Walsh, Jonathan Newchurch, Mark Robert Bleackley

“…IHL-675 A is Incannex Healthcare Pty Ltd.’s proprietary product formulated using UniGel™ technology consisting of a solid, film coated HCQ tablet contained within a CBD-oil solution gel cap. Each IHL-675 A gel cap contains 75 mg of CBD and 100 mg HCQ. …”
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Process Parameter Study on New Electrochemical Chloride Extraction of Corroded Concrete in Marine Environment by HE Lang

“…Experimental results showed that the ECE efficiency increased with the increase of current density, and the optimal current density was 2 A/m2 after overall consideration. …”
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ASIC2 subunits facilitate expression at the cell surface and confer regulation by PSD-95. by Anne Marie S Harding, Nobuyoshi Kusama, Tomonori Hattori, Mamta Gautam, Christopher J Benson

“…We found that ASIC2 increased cell surface levels of the channel when it is coexpressed with ASIC1a, and genetic deletion of ASIC2 reduced acid-evoked current amplitude in mouse hippocampal neurons. …”
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Correlation between quantitative traits and grain productivity of the waxy maize hybrids by G. Ya. Krivosheev, A. S. Ignatiev, D. R. Lupinoga, Yu. B. Arzhenovskaya, N. A. Shevchenko

“…The absence of domestic waxy maize hybrids in the State List of Breeding Achievements necessitates the study in this area of breeding. The purpose of the current study was to identify dependencies that make it possible to increase the efficiency of the breeding process when developing waxy maize hybrids. …”
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Leasing impact on transformation processes in the Russian agricultural sector under sanctions pressure by A. A. Kiritsa, Yu. V. Chutcheva

“…With consideration to  the current situation in   the domestic market, decreased prices for agricultural products and rapid growth of   prices for agricultural machinery, the most promising areas for the use of  leasing mechanisms have been proposed to   help accelerate technical re-equipment in   the agricultural sector: application of   leasing solutions in   the agricultural industry that have already been tested and proven successful in   other market segments (for example, subscription, agrocarsharing, etc.); combination of   leasing mechanisms with trade-in programmes which make it  possible to  comprehensively solve issues not only of   updating machinery and tractor fleet, but also of  recycling worn-out agricultural equipment; use of   leasing mechanisms for the development of  machine and technological complexes as a   modern form of  joint use of   machinery in  agriculture which allows accelerating technical equipment of   the industry. …”
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Fungal Δ9-fatty acid desaturase: a unique enzyme at the core of lipid metabolism in Aspergillus fumigatus and a promising target for the search for antifungal strategies by Jonatas Erick Maimoni Campanella, Leonardo Talachia Rosa, Iran Malavazi

“…A notable group of UFA found in these molecules contains a cis double bond located at the C9 position of the carbon chain. …”
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Research Advances of Prevention and Control of Hydrogen Sulfide in Coal Mines by Qigen Deng, Jingping Yin, Xifa Wu, Tao Zhang, Hao Wang, Mingju Liu

“…The methods used mainly include neutralization by injecting alkalizer through drilling in coal seams with high pressure, spraying alkalizer in tunnel, attenuation by increasing wind amount, changing the ventilation method, pumping, dredging, and blocking the water that contains H2S as well as comprehensive prevention and control method. …”
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Development and quality assessment of Coalho cheese using indigenous Pakistani milk sources: Nili-Ravi buffalo and Kamori goat by Wahab Ali Khan, Iqra Yasmin, Syed Abdul Wadood, Abbas Khan, Aiza Qamar, Maryam Hameeda, Fatima Farooq Ali, Khunsha Qamar Khan

“…Cheese FAME showed that source of milk is the major contributor to variation; however, during storage, the value of short-chain fatty acids increases. The current study enlightens the potential of blending buffalo and goat milk for the manufacturing of high-quality Coalho cheese, which not only addresses the need for improving the milk utilization but is also vital for value addition prospects. …”
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Automatic Guided Vehicles Introduction Impacts to Roll-On/Roll-Off Terminals: Simulation and Cost Model Analysis by Sang Hyung Park, Jeho Hwang, Sohyun Yun, Sihyun Kim

“…Results revealed that a system using 29 AGVs matched the productivity of the current loading system, and using more AGVs increased the productivity. …”
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Sustainable agricultural mechanization in Timor-Leste: status, challenges and further action by Jelle Van Loon, Mayling Flores Rojas

“…Beyond this, a reform of the current government mechanization hire schemes is needed: integrated approaches, as found from business model analyses and training exercises during field missions, are needed, that entail context-specific solutions for targeted rural communities, with special attention given to participatory extension, inclusive co-validation of technologies, and private sector-led business model development around mechanization service delivery. …”
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Analysis About the Effect of Dielectric Film Surface Residual Charge on Vibration of Filter Capacitor Core by Shuai WANG, Lin LI, Jianye CUI, Shousheng ZHAO, Pengning ZHANG, Yaqi WANG, Qiang HE

“…The noise of filter power capacitor in high voltage direct current (HVDC) converters is becoming increasingly prominent. …”
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Dynamics of educational activity of students under the influence of digitalisation by D. Yu. Narkhov, E. N. Narkhova, D. V. Shkurin

“…This study is based on the use of specific approaches to industry-specific sociological knowledge (youth and education): community, system, structural-functional, institutional, temporal, thesaurus, network, panoramic (pedagogical science). The current research employs the results of a mass survey conducted among students (N = 1825, 19 universities of the Sverdlovsk region) according to the authors’ method. …”
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Complementary Strategy of Maternal Immunization with RSVpreF Vaccine and Monoclonal Antibodies for the Prevention of Respiratory Syncytial Virus Among Italian Infants: A Cost-Effec... by Barbara Polistena, Fabio Midulla, Giovanni Sotgiu, Daniela d’Angela, Roberto Di Virgilio, Federico Spandonaro

“…Methods Using a model (with a cohort framework and a Markov-type process) specifically adapted to the Italian context, the study provided cost-effectiveness and cost-utility assessment of prevention strategies adding the maternal vaccination to the existing immunization opportunities with palivizumab or nirsevimab administered to high risk and unprotected infants. …”
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Protocol for a randomized controlled trial of patient–portal–based screening for substance use among people with HIV by Eric Roessler, Daniela Zimmer, Jon Grant, Harold Pollack, Basmattee Boodram, Jessica Schmitt, Jessica Schmitt, Eleanor Friedman, Jade Pagkas-Bather, Jade Pagkas-Bather, Russell A. Brewer, Jessica Ridgway, Neda Laiteerapong, Neda Laiteerapong

“…This will lay the groundwork for the second aim, the focus of the current manuscript, RCT to measure the effectiveness of a population health, patient portal-based substance use screening program. …”
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Insomnia, Cognitive Impairment, or a Combination of Both, Alter Lipid Metabolism Due to Changes in Acylcarnitine Concentration in Older Persons by Selma Karime Castillo-Vazquez, Berenice Palacios-González, Marcela Vela-Amieva, Isabel Ibarra-González, Ricardo Morales, Paola García-delaTorre, Sergio Sánchez-García, Carmen García-Peña, Ricardo Reyes-Chilpa, Raúl Hernán Medina-Campos, Jessica Hernández-Pineda, Juan Carlos Gomez-Verjan, Nadia Alejandra Rivero-Segura

“…However, the relationship between the two entities (insomnia and CI) is poorly understood. In this context, adults with insomnia show metabolic changes, including alterations in the catabolism of branched-chain amino acids, glycerophospholipids, and glutathione and glutamate biosynthesis. …”
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Increasing day three parasitaemia is observed after treatment of patients with artemether-lumefantrine and single dose of primaquine for uncomplicated Plasmodium falciparum malaria... by Bontu Abate, Bokretsion Gidey Brhane, Tsegahun Manyazewal, Hussien Mohammed, Yonas Wuletaw, Moges Kassa, Mesay Hailu, Getachew Tollera, Geremew Tasew, Ashenafi Assefa, Eyasu Makonnen

“…These findings support the ongoing use of AL with a single dose of PQ as the primary treatment option for uncomplicated P. falciparum infections in the study area. In the context of the emergence and spread of partial artemisinin-based combination therapy(ACT) resistance in Africa, regular monitoring of the efficacy of current artemisinin-based combinations is recommended for the early detection of emerging drug resistance in the study setting and beyond.…”
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Impact of Climate Change on the Narrow Endemic Herb Psilopeganum sinense (Rutaceae) in China by Ruixiong Deng, Kaitong Xiao, Xin Chen, Beibei Huang, Haoran Li, Lin Wu, Hang Ning, Hui Chen

“…Our results not only provide a scientific basis for managing P. sinense resources in the context of climate change but also serve as an important reference for restoring wild P. sinense populations.…”
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Enhancing Microgrid Protection With Impedance-Based Blocking: An Embedded Validation on a Dual-Layer Architecture by Thiago S. Menezes, Ricardo A. S. Fernandes, Denis V. Coury

“…Intelligent electronic devices close to the DERs receive voltage and current phasors, allowing the estimation of the impedance value used in the blocking strategy. …”
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UE Context Dissemination in Sparse LEO Constellations for 5G/6G Cellular IoT in Store and Forward Operation by Timo Kellermann, Roger Pueyo Centelles, Anna Calveras

“…The rapid expansion of the Internet of Things (IoT) highlights the need for ubiquitous connectivity, especially in remote and underserved areas. As a cornerstone of current 5th Generation (5G) cellular IoT networks, Narrowband IoT (NB-IoT) supports diverse massive Machine-Type Communications (mMTC) applications. …”
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Deconstruction of “The Pilgrim’s Progress” by John Bunyan in Kurt Vonnegut’s “Slaughterhouse-Five, or The Children’s Crusade” by Nataliya Krynytska

“…The US national mythology, one of the components of which is the Puritan cultural heritage, has recently increasingly attracted the attention of researchers of contemporary American literature. …”
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