Advancing the therapeutic effectiveness of paclitaxel in chronic lymphocytic leukemia through the simultaneous inhibition of NOTCH1 and SF3B1 by Shiva Abolhasani, Armin Mahmoud salehi Khesht, Atefeh Khodakarami, Ali Masjedi, Bentolhoda Rashidi, Sepideh Izadi, Fatemeh Karimian Noukabadi, Vahid Karpisheh, Khatereh Torabi Poudeh, Pooya Jalali, Zahra Salehi, Rafieh Bagherifar, Seyyed Sina Hejazian, AliAkbar Movassaghpour, Abbas Ali Hosseinpour Feizi, Farhad Jadidi

“…The enrichment analysis highlighted the fundamental pathways where the NOTCH1- and SF3B1-associated ceRNA network exerts its influence in the context of CLL. Conclusions This study implies the efficacy of combined therapy by CL-NPs loaded with anti-NOTCH1/-SF3B1 siRNAs and PTX as a novel therapeutic strategy for CLL, even though further studies are required to warrant the findings. …”
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Corrosion Performance of Chemically Passivated and Ion Beam-Treated Austenitic–Martensitic Steel in the Marine Environment by Viktor Semin, Alexander Cherkasov, Konstantin Savkin, Maxim Shandrikov, Evgeniya Khabibova

“…Immersion for 140 h in a solution containing 0.05 M potassium dichromate and 10% phosphoric acid promotes formation of chromium hydroxides in the outer surface layer. …”
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Impact of frailty in older people on health care demand: simulation modelling of population dynamics to inform service planning by Bronagh Walsh, Carole Fogg, Tracey England, Sally Brailsford, Paul Roderick, Scott Harris, Simon Fraser, Andrew Clegg, Simon de Lusignan, Shihua Zhu, Francesca Lambert, Abigail Barkham, Harnish Patel, Vivienne Windle

“…Prescriptions increased with increasing age in both Fit and Mild frailty categories but decreased in moderate and severe categories. …”
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Effectiveness of AdaBoost and XGBoost Algorithms in Sentiment Analysis of Movie Reviews by I Gusti Ayu Nandia Lestari, Ni Made Rai Masita Dewi, Komang Gita Meiliana, I Komang Agus Ady Aryanto

“…Currently there are many entertainment platforms that provide various movies, TV shows, games, and other content. …”
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Contact Lenses in Pediatric Ophthalmological Practice by E. Yu. Markova, E. A. Perfilyeva

“…Currently, the indication for contact lenses use in children are the same as for the adults (with certain specific and limitations). …”
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Numerical Analysis of Leakage and Diffusion Characteristics of In-Situ Coal Gas with Complex Components by Enbin Liu, Lianle Zhou, Ping Tang, Bo Kou, Xi Li, Xudong Lu

“…Currently, the area of consequence of the harm caused by a leak in a gathering pipeline transporting in-situ coal gas has not been clarified. …”
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Pharmaceutical Providing for Prevention and Treatment of Influenza in Children by Olіynyk O., Kіrda І., Voitsekhivska I.

“…The mortality rate of uncomplicated influenza is 0.01-0.2 %, but it increases sharply in the case of illness in frail persons and young children. …”
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Validated UHPLC Methods for Melatonin Quantification Reveal Regulatory Violations in EU Online Dietary Supplements Commerce by Celine Vanhee, Cloë Degrève, Niels Boschmans, Yasmina Naïmi, Michael Canfyn, Eric Deconinck, Marie Willocx

“…Moreover, 12% of legal supply chain samples violated current legislation through unauthorized health claims or contained at least triple the melatonin amount permitted in Belgium. …”
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Explorative Study of Modulatory Effects of Notochordal Cell‐Derived Extracellular Vesicles on the IL‐1β‐Induced Catabolic Cascade in Nucleus Pulposus Cell Pellets and Explants... by J. C. vanMaanen, F. C. Bach, J. W. Snuggs, K. Ito, M. H. M. Wauben, C. L. Le Maitre, M. A. Tryfonidou

“…Modification of the CCL2 secretion seemed to be context dependent in the human explants: where EVs treatment stimulated CCL2 secretion but in the presence of IL‐1β this effect was counteracted. …”
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Oxidation behaviour of Ti-V-Cr-Nb-Ta and Al-Ti-V-Cr-Ta refractory high entropy alloys: Effects of Nb and Al substitutions by Kieran Rivers, Bradley Young, Yuanbo T. Tang, Bo-Shiuan Li, Angus J. Wilkinson, David E.J. Armstrong, Junliang Liu

“…However, a significant issue with current RHEAs is that those exhibiting good mechanical properties tend to show poor oxidation resistance, and vice versa. …”
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Emergency Care for Suicidal Behavior Before and During the COVID-19 Pandemic in Two Hospitals in Bogotá: a Longitudinal Analysis by Gutiérrez-Dajud, Sasha Stefany, Pastran-Cortés, Ana María, Mendivelso, Fredy, Rodríguez-Bedoya, Ingrid Milena, Moreno-Gómez, Jairo Enrique, Muñoz-Tamayo, Rodrigo

“…Suicidal ideation was the most documented typology during the pandemic (p <0.001), and the prevalence of suicidal behavior among children and adolescents (≤18 years) increased from 29% to 33%. Conclusions: Theresults suggest that the pandemic catalyzed the number of admissions for suicidal behavior in the general population after the implementation of containment measures or contagion prevention restrictions. …”
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A pilot study on physiological relaxation and enhanced work performance by volatile organic compounds emitted from Kagawa hinoki (Chamaecyparis obtusa) interior walls by Fumi Kishida, Kazuki Tani, Taisuke Nakashima, Fadilla Zennifa, Akiko Isa, Noboru Fujimoto, Koki Fujita, Ryuma Taki, Hiroo Yasutomi, Naotoshi Yasumori, Kuniyoshi Shimizu

“…This timber was reported to have a relaxing effect toward the participants, and this study discovered that inhaling air containing VOCs emitted by Kagawa hinoki interior walls increased parasympathetic nervous activity during resting periods between arithmetic tasks. …”
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Association Analysis of the Genomic and Functional Characteristics of Halotolerant <i>Glutamicibacter endophyticus</i> J2-5-19 from the Rhizosphere of <i>Suaeda salsa</i> by Longhao Sun, Shanshan Sun, Tianyang Liu, Xinmin Lei, Ruiqi Liu, Junyi Zhang, Shanshan Dai, Jing Li, Yanqin Ding

“…Halotolerant plant growth-promoting bacteria (HT-PGPB) have attracted considerable attention for their significant potential in mitigating salt stress in crops. However, the current exploration and development of HT-PGPB remain insufficient to meet the increasing demands of agriculture. …”
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Effect of hybrid reinforcements of TiO₂, Al₂O₃, and CNTs on superior mechanical and microstructural properties in epoxy/carbon fiber composite by N. Elzayady, Walid Mahmoud Shewakh, Mohamed Abu-Okail, H.T. Elmetwaly, A.M.I. Abu-Oqail

“…The current study focuses on multi-scale dual-hybrid composites. …”
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Optimizing nitrogen removal in advanced wastewater treatment using biological aerated filters by Juan Li, Juan Li, Ziru Niu, Ziru Niu, Lei Li, Shuting Zhou

“…In order to address this issue, the current study employed a biological aerated filter for the treatment of wastewater containing low nitrogen concentrations. …”
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Development and evaluation of superhydrophobic carbon nanotube coatings onmaraging steel: Corrosion protection, and anti-fouling characteristics by F.abdel Mouez, H. Halfa, Ahmed Yahia, H.M. Hussien, Mohab Gaber, Heba H. Ali

“…Atomic force microscopy indicated a substantial increase in surface roughness, contributing to the superhydrophobic behavior. …”
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Electrodeposited Ni-Sn coatings as electrocatalysts for hydrogen and oxygen evolution in alkaline solutions by U.Č. Lačnjevac, Krstajić Lj. Gajić, N.V. Krstajić

“…It was shown that among the increase of the roughness factor of Ni- Sn coatings with the increase of electrodeposition current density, their composition was also responsible for their catalytic activity for both, the HER and the OER. …”
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Study on Treatment of Loess Landslide Based on Nanosilica and Fly Ash Composite Stabilizer Filling Fissures by Jiulong Gao, Jiading Wang, Yao Wei, Shaotong Jiao, Meng Jing, Jialing Gao, Cong Wang

“…A new type of grouting material was used to fill the fissures and reinforce the loess in the slip zone, so as to study the effect of material content on the slope stability. With current methods, loess specimens were taken from the slip zone inside the Lvliang Airport slope. …”
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Strengths and Knowledge Gaps Identified From Cybersecurity Education and Training Programs, and the Implications for Operational Technology Personnel in Critical Infrastructures: A... by Leanne Noelle Strom Torgersen, Elizabeth Rebecca Noble, Torvald Fossaen Ask, Benjamin J. Knox

“…With the advent of digitalization and Industry 4.0, these infrastructures have transitioned from offline, self-contained systems to digitally interconnected networks. …”
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The role of motivation in weight reduction programs for children and adolescents with overweight or obesity: a systematic review by Anne Herschbach, Annalena Wels, Pauline Dieckmann, Rebecca Erschens, Florian Junne, Stefan Ehehalt, Stephan Zipfel, Katrin Elisabeth Giel, Katrin Ziser

“…More research is needed to implement the current findings in future pediatric weight reduction programs. …”
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