Case Report: Locally invasive thyroid metastases from renal cell carcinoma: surgery after neoadjuvant therapy by Dana M. Hartl, Mohamed-Amine Bani, Abir Al Ghuzlan, Andreea-Elena Simonescu, Ingrid Breuskin, Alix Marhic, Laurence Albiges, Laurence Albiges, Livia Lamartina, Livia Lamartina, Julien Hadoux, Julien Hadoux

“…Patient 1 received lenvatinib and a bispecific anti–Programmed cell Death protein 1/ cytotoxic T-lymphocyte-associated protein 4 (PD-1/CTLA-4) antibody in the context of a clinical trial. The second patient received nivolumab and cabozantinib.ResultsThe observed tumor response in patient 1 showed a decrease in mean surgical complexity score from unresectable (prevertebral fascia invasion) to severe (risk of recurrent nerve paralysis) and in patient 2 from unresectable (prevertebral fascia) to moderate (superficial esophageal invasion). …”
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Unveiling biomarkers via plasma metabolome profiling for diabetic macrovascular and microvascular complications by Zhixi Li, Yuhan Ren, Feng Jiang, Kai Zhang, Xuan Meng, Yingfeng Zheng, Mingguang He

“…As for reverse MR, DN was relevant to decreased level of serum ratio of docosahexaenoic acid to total fatty acids (OR = 0.97, 95% CI 0.95–0.99, P = 0.019), increased level of the ratio of triglycerides to total lipids in very large VLDL (OR = 1.03, 95% CI 1.01–1.05, P = 0.019), and pyruvate (OR = 1.03, 95% CI 1.01–1.05, P = 0.046). …”
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Evaluating inhaled corticosteroids' impact on osteoporosis and fracture risk in COPD patients: a real-world evidence-based systematic review and meta-analysis by Hsiao-Feng Huang, Chin-Wei Hsu, Chin-Wei Hsu, Chin-Wei Hsu, Fei-Ting Hsieh, Kuang-Ming Liao, Kuang-Ming Liao

“…Subgroup analyses indicated a potential increased risk in Asian and European populations but not in North America. …”
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The XEC Variant: Genomic Evolution, Immune Evasion, and Public Health Implications by Alaa A. A. Aljabali, Kenneth Lundstrom, Altijana Hromić-Jahjefendić, Nawal Abd El-Baky, Debaleena Nawn, Sk. Sarif Hassan, Alberto Rubio-Casillas, Elrashdy M. Redwan, Vladimir N. Uversky

“…The XEC strain of SARS-CoV-2 has drawn particular attention due to its increasing prevalence in multiple regions and its potential to displace other Omicron subvariants, although direct evidence of enhanced replicative fitness is currently lacking. …”
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The Effect of Gamified Physical Activities on the Quality of Students' Leisure Time (Case Study: Female Secondary School Students in Ardabil City) by aylar sefidgar, Hamed Kheirollahi Meidani, Mehrdad Moharramzadeh

“…Its reliability was also established, achieving a Cronbach's alpha coefficient of 0.95, which demonstrates the high reliability of the questionnaire used in the current study. The questionnaire contains 64 items divided into four components: decision-making skills, leisure awareness skills, social relations skills, and self-awareness skills. …”
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Laparoscopic sleeve gastrectomy performed in a morbidly obese patient with gastrointestinal stromal tumor: a case report and literature review by Kenkichi Hashimoto, Yoshihisa Sakaguchi, Sho Nambara, Kensuke Kudou, Eiji Kusumoto, Keiji Yoshinaga, Tetsuya Kusumoto, Koji Ikejiri

“…Abstract Background Gastrointestinal stromal tumor (GIST) is the most frequent submucosal tumor, and with advancements of diagnostic modalities, the incidence of GIST cases diagnosed have increased. Similarly, prevalence of morbid obesity has also rapidly increased over the past decade. …”
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Unraveling the dynamics of dengue in Metahara town, East Shewa, Oromia, Ethiopia, 2023. by Bikila Negesa Gobena, Teshome Kabeta Dadi, Gemechu Chemeda Feyisa, Birhanu Kenate, Gemechu Shumi, Fantahun Workie, Haimanot Workie, Ebise Djirata, Dabesa Gobena

“…<h4>Background</h4>Since 2013, dengue cases have shown a marked increase in Ethiopia. The current suspected outbreak occurring in Metahara town, Oromia Regional State, began in July 2023. …”
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Drug-induced acute myocardial infarction: identifying 'prime suspects' from electronic healthcare records-based surveillance system. by Preciosa M Coloma, Martijn J Schuemie, Gianluca Trifirò, Laura Furlong, Erik van Mulligen, Anna Bauer-Mehren, Paul Avillach, Jan Kors, Ferran Sanz, Jordi Mestres, José Luis Oliveira, Scott Boyer, Ernst Ahlberg Helgee, Mariam Molokhia, Justin Matthews, David Prieto-Merino, Rosa Gini, Ron Herings, Giampiero Mazzaglia, Gino Picelli, Lorenza Scotti, Lars Pedersen, Johan van der Lei, Miriam Sturkenboom, EU-ADR consortium

“…Outcome of interest was statistically significant increased risk of AMI during drug exposure that has not been previously described in current literature and is biologically plausible.…”
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EXTREME WINTERS IN XX–XXI CENTURIES AS INDICATORS OF SNOWINESS AND AVALANCHE HAZARD IN THE PAST AND EXPECTED CLIMATE CHANGE CONDITIONS by A. D. Oleynikov, N. A. Volodicheva

“…Currently, due to the global climate change and increasing frequency of weather events focus is on prediction of climate extremes. …”
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Incidence and trends of limb amputation in first nations and general population in Saskatchewan, 2006-2019. by Samuel Kwaku Essien, Gary Linassi, Margaret Larocque, Audrey Zucker-Levin

“…Overall and primary LA rates for the GP Group declined 0.7% and 1.0%, while subsequent LA increased 0.1%. An increased LA rate for all categories (overall 4.9%, primary 5.1%, and subsequent 4.6%) was identified in the RI group. …”
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Addressing ‘wicked complex problems’: Qualitative understandings of sexual violence prevention in male-dominated industries by Sarah Vrankovich, Sharyn Burns, Giselle Woodley, Jacqueline Hendriks

“…This research aims to provide an understanding of current sexual violence prevention initiatives within the Australian mining sector, offering recommendations for future approaches tailored to industries and contexts with similar dynamics.…”
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“Dig Your Heels in the Ground and Get What You Deserve.” - An Exploratory Corpus-Assisted Study of Women Entrepreneurs’ Blogs. by Katarzyna Fronczak

“…However, recent decades have witnessed increased visibility of women entrepreneurs striving to challenge gender-based inequities and systemic biases in the workplace. …”
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Essential Pieces of the Puzzle: The Roles of VEGF and Dopamine in Aging by Melanie B. Thompson, Sanjay P. Tirupattur, Nandini Vishwakarma, Laxmansa C. Katwa

“…Aging is a well-known, complex physiological process characterized by progressive functional decline and increased susceptibility to disease, particularly in the cardiovascular and nervous systems. …”
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The composition of anodic oxide films on InAs crystals by A. V. Artamonov, V. P. Astakhov, I. B. Varlashov, N. I. Evstaf’Eva, P. V. Mitasov

“…In turn, the forming voltage increasing at fixed current density also increases the fluorine concentration near InAs-AOF boundary but in less extent: with forming voltage increasing on 5 V more the fluorine content in the bulk AOF increases in ~1.2 and ~1.5 times at current densities of 0.05 and 0.5 mA/cm2, respectively. …”
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Protective Effect of Fenugreek Supplementation against Mercury Toxicity on Sperm Parameters, Serum Testosterone and Testicular Tissue in the Rat by Jalal A. Karim, Karim R. Hamad

“…Group I: control, Group II: Rats received drinking water contained HgCl2 100 mg/L ad libitum, Group III: Rats received drinking water contained HgCl2 100 mg/L ad libitum, and fenugreek (F1) 0.75 mg/kg/day orally by gavage, Group IV: Rats received drinking water contained HgCl2 100 mg/L ad libitumand fenugreek (F2) 1.5 mg/kg/day orally by gavage. …”
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CAR-T cells and TRUCKs that recognize an EBNA-3C-derived epitope presented on HLA-B*35 control Epstein-Barr virus-associated lymphoproliferation by Michael Hudecek, Anna Christina Dragon, Katharina Zimmermann, Thomas Nerreter, Deborah Sandfort, Julia Lahrberg, Stephan Klöß, Christina Kloth, Caroline Mangare, Agnes Bonifacius, Sabine Tischer-Zimmermann, Rainer Blasczyk, Britta Maecker-Kolhoff, Barbara Uchanska-Ziegler, Hinrich Abken, Axel Schambach, Britta Eiz-Vesper

“…Background Immunosuppressive therapy or T-cell depletion in transplant patients can cause uncontrolled growth of Epstein-Barr virus (EBV)-infected B cells resulting in post-transplant lymphoproliferative disease (PTLD). Current treatment options do not distinguish between healthy and malignant B cells and are thereby often limited by severe side effects in the already immunocompromised patients. …”
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Arthroscopic-Assisted vs. Fluoroscopic-Only ORIF of Distal Radius Fractures: Clinical and Economic Perspectives by Wolfram Demmer, Antonina Jakob, Fabian Gilbert, Benedikt Fuchs, Sinan Mert, Nikolaus Wachtel, Riccardo Giunta, Verena Alt

“…Our findings demonstrate that DRF treatment, regardless of the method used, is either not or only marginally cost-covering under the current German reimbursement structure. In the context of the ongoing shift towards outpatient hand surgery, including the management of DRF, adequate reimbursement rates are necessary to ensure the economic viability of DRF management, particularly for complex intra-articular fractures requiring arthroscopic assistance.…”
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Pesticide Residues in Fruits and Vegetables from Cape Verde: A Multi-Year Monitoring and Dietary Risk Assessment Study by Andrea Acosta-Dacal, Ricardo Díaz-Díaz, Pablo Alonso-González, María del Mar Bernal-Suárez, Eva Parga-Dans, Lluis Serra-Majem, Adriana Ortiz-Andrellucchi, Manuel Zumbado, Edson Santos, Verena Furtado, Miriam Livramento, Dalila Silva, Octavio P. Luzardo

“…Food safety concerns related to pesticide residues in fruits and vegetables have increased globally, particularly in regions where monitoring programs are scarce or inconsistent. …”
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A scoping review of HIV epidemiologic, sociocultural and programmatic studies related to transgender women and men who have sex with men in Cambodia, 1999-2019. by Jan W de Lind van Wijngaarden, Frits van Griensven, Ly Penh Sun, Stephen Wignall

“…A few evaluation studies were found, but it remains unknown how effective current HIV service implementation modalities are, or how successful strategies to increase access to essential HIV prevention, testing and treatment services have been employed for MSM and TGW in Cambodia.…”
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Controlling factors and exploration potential of shale gas enrichment and high yield in Permian Dalong Formation, northern Sichuan Basin, SW China by Rui YONG, Hongzhi YANG, Wei WU, Xue YANG, Yuran YANG, Haoyong HUANG

“…Second, the Dalong Formation shale contains both organic and inorganic pores, with stratification of alternated brittle and plastic minerals. …”
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