Dual Reporter Gene Imaging by Jiantu Che, Mikhail Doubrovin, Inna Serganova, Ludmila Ageyeva, Pat Zanzonico, Ronald Blasberg

“…These studies indicate the potential for a wider application of hNIS reporter imaging and translation into patient studies using radioisotopes that are currently available for human use for both SPECT and PET imaging.…”
Get full text

Dengue virus serotype 2 infection alters midgut and carcass gene expression in the Asian tiger mosquito, Aedes albopictus. by Hitoshi Tsujimoto, Kathryn A Hanley, Anitha Sundararajan, Nicholas P Devitt, Faye D Schilkey, Immo A Hansen

“…<h4>Background</h4>The Asian tiger mosquito, Aedes albopictus is currently an important vector for dengue, chikungunya and Zika virus, and its role in transmission of arthropod-borne viruses (arboviruses) may increase in the future due to its ability to colonize temperate regions. …”
Get full text

“Green approach for corrosion inhibition for Fe-metal in acidic medium using Banaba leaves (Lagerstroemia speciosa) extract and ZnO nanoparticles” by Supriya Vykuntam, Nandhini R., Nandhini G., Anugraha J., Sakthisri R.

“…Using green corrosion inhibitors derived from Banaba leaf extracts to prevent metals in acidic media is the aim of this study. Currently, there is a greater interest in adopting green alternatives due to environmental concerns and human health risks related with synthetic inhibitors. …”
Get full text

What do we really know about brucellosis diagnosis in livestock worldwide? A systematic review. by Sonia Vection, Christopher G Laine, Angela M Arenas-Gamboa

“…This highlights, not only significant gaps in currently available literature leading to an inaccurate picture of brucellosis in livestock, but most importantly raises significant issues regarding the accuracy of data reported by countries. …”
Get full text

Intelligent micro-electro-mechanical system for predictive nano-drug synthesis: Acousto-microfluidic heat and mass transportation by Afshin Kouhkord, Fariddodin Hassani, Ali Golshani, Reza Ansari

“…Integrated microfluidic designs enhance nanoparticle reproducibility and therapeutic effectiveness by precisely controlling heat and mass transfer in microfluidic design process. In these contexts, even minor changes in nanoparticle properties due to slight variations in synthesis conditions can significantly influence therapeutic outcomes, addressing current limitations and promoting successful clinical translation.…”
Get full text

Global, Regional, and National Burden of Nonrheumatic Valvular Heart Disease and Its Attributable Risk Factors in 204 Countries and Territories, 1990 to 2019: Results From the Glob... by Le Li, Limin Liu, Zhicheng Hu, Likun Zhou, Zhuxin Zhang, Lingmin Wu, Ligang Ding, Zhao Hu, Lihui Zheng, Yan Yao

“…Background Nonrheumatic valvular heart disease (NRVD) is increasingly becoming a significant public health concern, particularly among older people. …”
Get full text

Exploring the correlation between tree structure characteristics and carbon storage in historic gardens using TLS technology: a case study of Jian Xin Pavilions at Jingyi Park, Fra... by Cuiyu Ouyang, Xiaoxiao He, Ruipeng Lin, Ke Qin

“…Abstract Historic gardens contain a greater number and variety of ancient trees, which are older, have unique forms, and larger volumes. …”
Get full text

Effects of long-term pioglitazone treatment on peripheral and central markers of aging. by Eric M Blalock, Jeremiah T Phelps, Tristano Pancani, James L Searcy, Katie L Anderson, John C Gant, Jelena Popovic, Margarita G Avdiushko, Don A Cohen, Kuey-Chu Chen, Nada M Porter, Olivier Thibault

“…Finally, a combination of microarray analyses on hippocampal tissue and serum-based multiplex cytokine assays revealed that age-dependent inflammatory increases were not reversed by PIO.<h4>Conclusions</h4>While current research efforts continue to identify the underlying processes responsible for the progressive decline in cognitive function seen during normal aging, available medical treatments are still very limited. …”
Get full text

Cr doping modification for tribological behavior of Cr/a-C multilayer coatings against PEEK under diverse operational conditions by Xiaohui Zhou, Yingpeng Zhang, Hao Li, Li Cui, Wei Yang, Aiying Wang, Peng Guo, Peiling Ke

“…Considering the increasing demand for wear-resistant materials used for various frictions with dynamic sealing parts, we employed hybrid magnetron sputtering technology to fabricate Cr/amorphous carbon (a-C) multilayered coatings with and without Cr doping for comparison. …”
Get full text

Driving Factors of Urban–Rural Human Settlement Changes and a Multi-Scenario Simulation Based on SDGs by Yang Ye, Yantong Liu, Jingyi Liu, Zhiyi Weng, Ziyao Chang, Xiong Li

“…The ecosystem service value and SDG values gradually increased, displaying a clustering pattern of northern highs and southern lows. …”
Get full text

Study on the influence of load and sliding speed on the friction behavior of electrodeposited Ni–SiC composite coatings by Pao-Chang Huang, An-Yu Cheng, Chih-Cheng Chou, Jung-Sen Huang, Zi-An Wang, Kung-Hsu Hou

“…Increasing sliding speed significantly reduced wear and coefficient of friction (COF), attributed to the formation of a continuous tribo-oxidative layer. …”
Get full text

Norbornenic anhydride as versatile additive optimizing interphases to enable high-performance LiNi0.8Co0.1Mn0.1O2/Li batteries by Fujie Yang, Zihao Yang, Qiujie Huang, Pipi Wang, Chong Mao, Zhanqiang Li, Huiyang Li, Xudong Chen

“…A LiǁLi symmetric cell with NA exhibits excellent cycling stability at a current density of 1.0 mA cm−2 for cycling 400 h. …”
Get full text

Understanding data and information needs for palliative cancer care to inform digital health intervention development in Nigeria, Uganda and Zimbabwe: protocol for a multicountry q... by Richard Harding, Bassey Ebenso, Adlight Dandadzi, Eve Namisango, Kehinde Okunade, Kennedy Bashan Nkhoma, Omolola Salako, David Akeju, Olaitan Soyannwo, Elizabeth Namukwaya, Elizabeth Nabirye, Lovemore Mupaza, Emmanuel Luyirika, Henry Ddungu, Z Mike Chirenje, Michael I Bennett, Matthew J Allsop

“…However, there is currently a lack of any theoretical underpinning or data to understand stakeholder drivers for digital health components in this context. …”
Get full text

Neutrophil-to-Lymphocyte ratio as surrogate for JAK2V617F suppression and event-free survival in polycythemia vera by Tiziano Barbui, Arianna Ghirardi, Victoria Empson, Francesca Fenili, Giuseppe Gaetano Loscocco, Annalisa Condorelli, Alessandra Iurlo, Daniele Cattaneo, Elena Rossi, Valerio De Stefano, Paola Guglielmelli, Christoph Klade, Heinz Gisslinger, Alessandro Rambaldi, Joseph M. Scandura, Alessandro Maria Vannucchi

“…Abstract Chronic systemic inflammation is a key driver of polycythemia vera (PV) progression, but the immunomodulatory effects of current treatments remain poorly defined. The neutrophil-to-lymphocyte ratio (NLR) is an accessible biomarker of systemic inflammation proven in other contexts, but its role in monitoring PV disease activity has not been established. …”
Get full text

Avoiding Error and Finding the Right Balance in European Health Technology Assessments: Insights Generated by the European Access Academy by Elaine Julian, Tom Belleman, Maria João Garcia, Maureen Rutten-van Mölken, Robin Doeswijk, Rosa Giuliani, Bernhard J. Wörmann, Daniel Widmer, Patrick Tilleul, Ruben Casado Arroyo, Valentina Strammiello, Kate Morgan, Marcus Guardian, Michael Ermisch, Renato Bernardini, Fabrizio Gianfrate, Stefano Capri, Carin A. Uyl-de Groot, Mira Pavlovic, Jörg Ruof

“…This research aims to explore how to address these challenges in a balanced manner and prioritise key actions for effective collaboration in the context of the EU HTA. Methods: The methodology included a pre-convention survey among relevant stakeholders as well as working groups and the plenary ranking of discussion outcomes at the European Access Academy (EAA) Spring Convention 2024. …”
Get full text

Comparison of various feed additives on nutrient digestibility, digestive enzyme activity, blood metabolite levels, and gut microbiota composition in japanese quail chicks by Hassan Saleh, Omid Jangjou, Mohammad Taher Mirakzehi, Seyedeh Hamideh Hosseni

“…Results: Japanese quail chicks that were fed a diet containing iron oxide nanoparticles and antibiotics exhibited a statistically significant increase (p < 0.05) in body weight gain (BWG) between 1 and 5 weeks of age (5.65 and 5.67 g/d, respectively). …”
Get full text

Ethical implications related to processing of personal data and artificial intelligence in humanitarian crises: a scoping review by Tino Kreutzer, James Orbinski, Lora Appel, Aijun An, Jerome Marston, Ella Boone, Patrick Vinck

“…Ethical risks, particularly from artificial intelligence (AI) data processing, are increasingly recognized yet inadequately addressed by current humanitarian data protection guidelines. …”
Get full text

A whole process resilience management practice in coastal engineering by Yingtao Zhou, Yingtao Zhou, Yingtao Zhou, Chenhui Jiang, Yuanshu Jiang, Yu Zhu, Yu Zhu, Yu Zhu, Yan Jin, Xian Wang, Xi Feng, Weibing Feng

“…Coastal zones are crucial for protecting land from marine disasters, but they are increasingly threatened by erosion caused by storms and rising sea levels. …”
Get full text

Clinical and cost-effectiveness of paramedics working in general practice: a mixed-methods realist evaluation by Matthew Booker, Sarah Voss, Nicky Harris, William Hollingworth, Nouf Jeynes, Hazel Taylor, Kirsty Garfield, Helen Baxter, Jonathan Benger, Andy Gibson, Trudy Goodenough, Justin Jagosh, Kim Kirby, Cathy Liddiard, Alyesha Proctor, Sarah Purdy, Behnaz Schofield, Hannah Stott, Grace Scrimgeour, Nicola Walsh

“…Background General practice services are under pressure due increased demand. Alongside substantial national recruitment challenges, there exists a shortage of general practitioners to meet current need. …”
Get full text

SHAZAM: Self-Supervised Change Monitoring for Hazard Detection and Mapping by Samuel Garske, Konrad Heidler, Bradley Evans, Kee Choon Wong, Xiao Xiang Zhu

“…The increasing frequency of hazardous events due to climate change underscores an urgent need for effective hazard monitoring systems. …”
Get full text