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3701
Unraveling the complex role of microglia in Alzheimer’s disease: amyloid β metabolism and plaque formation
Published 2025-05-01“…Conversely, we explore findings that challenge this view, such as microglial depletion experiments resulting in unchanged or decreased Aβ accumulation. We propose that the contribution of microglia to Aβ metabolism is context-dependent, varying with disease progression, genetic background, and experimental conditions. …”
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3702
CIS Countries Foreign Economic Activity — from Challenges to New Opportunities
Published 2024-12-01“…Aim and tasks. To identify current trends and issues in foreign trade, the international financial system, and the investment activity of CIS member states, and to provide recommendations that contribute to sustainable economic development and strengthened mutual cooperation.Methods. …”
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3703
Unlocking the hidden forces: deformation and associated stress distribution in the present-day Geneva Basin and Jura fold-and-thrust belt
Published 2025-06-01“…If current seismicity indicates that the Geneva Basin is tectonically active, few data regarding the state of stress in the area are currently available. …”
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3704
Social Skills Training Program and its Effect on Quality of Life and Stigma among Patients with Schizophrenia
Published 2025-04-01“… Context: Schizophrenia is a severe mental disorder that significantly disrupts an individual's social interactions, work performance, and overall quality of life. …”
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3705
Therapeutic potential of microRNAs in neurological disorders: mechanisms, biomarkers, and emerging therapeutic strategies
Published 2025-07-01“…This review critically evaluates current therapeutic strategies for miRNA delivery in neurological disorders, focusing on advanced platforms such as nanocarriers, exosomes, viral vectors, and ligand-mediated systems designed to overcome the blood-brain barrier. …”
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3706
Research Progress on the Impact of Nighttime Outdoor Environments on Residents’ Health
Published 2025-07-01“…As research in this area continues to expand, there is an urgent need to synthesize existing knowledge, identify current limitations, and provide guidance for future investigations. …”
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3707
The Anthropocene is shifting the paradigm of geosciences and science
Published 2022-12-01“…Noting that humans are affecting the Earth’s envelopes, with geosciences becoming inseparable from social sciences and humanities, and acknowledging the increasing use of the word Anthropocene, the authors of this paper explore the possibility of a scientific paradigm shift. (1) Since the 17th century, modern science has developed in a context of naturalist worlding that favors its hegemony over other modes of existence and its paradigm of a quest to define the laws of nature. (2) Various manifestations attest to the emergence of a paradigm of knowledge diversity and the unravelling of the naturalist worlding. (3) The current boom in participatory science is a sign of this paradigm shift: through the fundamental changes to the Earth System that refer to it, the Anthropocene forces science to move towards action and interact with a society involved in adapting to changes and concerned with the threats to its territory’s habitability.…”
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3708
An Innovation Machine Learning Approach for Ship Fuel-Consumption Prediction Under Climate-Change Scenarios and IMO Standards
Published 2025-04-01“…A sensitivity analysis identified vessel speed as the most critical factor, contributing 33% to the variance in fuel consumption, followed by engine power and current speed. Climate-change simulations showed that fuel consumption increases by an average of 22% for bulk carriers and 19% for container ships, highlighting the importance of operational optimizations. …”
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3709
Contextual Vulnerability Should Guide Fair Subject Selection in Xenotransplantation Clinical Trials
Published 2023-03-01“…This paper describes the current transplant system’s use of subjective evaluation criteria, particularly psychosocial support and compliance. …”
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3710
METABOLIC REPROGRAMMING OF MICROGLIA AND ASTROCYTES AS A FACTOR IN THE REGULATION OF NEUROINFLAMMATION IN ISCHEMIC STROKE
Published 2019-08-01“…This review presents current ideas about metabolic reprogramming in astrocytes and microglial cells in the context of pathophysiological processes in cerebral ischemia.…”
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3711
Unlocking the Shopper’s Mind: How Emerging Technologies Like Artificial Intelligence Is Shaping the Future of Retail
Published 2024-12-01“…While these approaches have been increasingly adopted by retailers, the current study investigates whether the drift toward digital platforms impacts the efficiency of neuromarketing strategies and how AI takes further priority in this direction (Goncalves et al., 2024). …”
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3712
Stacked-cup multiwall carbon nanotubes as components of energy-intensive suspension jet fuels
Published 2020-05-01“…The addition of high-density carbon materials to jet fuels can lead to a significant increase in the volumetric energy of the fuel combustion. …”
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3713
Sirtuins and Their Role in the Aging Eye (Review)
Published 2020-09-01“…The magnitude of this problem is becoming increasingly apparent as the population ages and the number of older people increases. …”
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3714
Blood-based biomarkers in mild behavioral impairment: an updated overview
Published 2025-02-01“…A growing number of studies have recently begun to explore the relationship between MBI and several blood-based biomarkers associated with Alzheimer’s disease (AD) pathology, neurodegeneration, as well as systemic metabolic and inflammatory dysregulation. In this context, MBI has been associated with lower plasma Aβ42/Αβ40 ratio, higher plasma phosphorylated tau at threonine 181 (p-tau181), increased neurofilament light chain (NfL) levels, as well as disturbances in metabolic markers, including homocysteine, insulin and ferritin, suggesting a multifaceted neurobiological basis for this syndrome. …”
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3715
Cell Therapy in Ischemic Heart Disease: Interventions That Modulate Cardiac Regeneration
Published 2016-01-01“…This review brings together current data on pharmacological and nonpharmacological approaches to improve cell homing and cardiac repair.…”
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3716
IAE-CDNet: A Remote Sensing Change Detection Network for Buildings With Interactive Attention-Enhanced
Published 2025-01-01“…Currently, the development of deep learning has had a positive impact on remote sensing image change detection tasks, but many current methods still face challenges in effectively processing global and local features, especially in the task of building change detection in high-resolution images containing complex scenes. …”
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3717
Job insecurity, work passion, and work–life balance in diverse work arrangements
Published 2025-05-01“…Orientation: The coronavirus disease 2019 (COVID-19) pandemic shifted work settings, revealing gaps in current literature on how work arrangements affect employee experiences and well-being. …”
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3718
Evidence of Transmission Capability in UK <i>Culex pipiens</i> for Japanese Encephalitis Virus (JEV) Genotype I and Potential Impact of Climate Change
Published 2025-06-01“…Japanese encephalitis virus (JEV) is a mosquito-borne orthoflavivirus and a major cause of human encephalitis throughout Asia, although it is currently not reported in Europe. To assess the potential impact of climate change, such as increased temperatures, and the potential for native <i>Cx. pipiens</i> to transmit JEV genotype I in the United Kingdom (UK), we have investigated vector competence at two different temperatures. …”
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3719
Modern ideas about the causes, pathogenesis and innovative areas of therapy for asthenic syndrome in clinical practice
Published 2024-11-01“…The most common tool for diagnosing AS is currently the Multidimensional Fatigue Inventory (MFI-20) questionnaire, and the L. …”
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3720
Extended evaluation of the effect of real and simulated masks on face recognition performance
Published 2021-09-01“…Processes such as secure login to electronic devices or identity verification at automatic border control gates are increasingly dependent on such technologies. The recent COVID‐19 pandemic has increased the focus on hygienic and contactless identity verification methods. …”
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