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2141
Immune regulation and the tumor microenvironment in anti-PD-1/PDL-1 and anti-CTLA-4 therapies for cancer immune evasion: A bibliometric analysis
Published 2024-12-01“…This bibliometric study seeks to provide a comprehensive overview of past and current research trends, emphasizing the potential role of tumor microenvironment, signaling pathways and immune cells in the context of immune checkpoint inhibitors (ICIs) and tumor immune evasion.…”
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2142
‘Just because something works doesn’t mean it can’t be improved’: an ethnographic analysis of the health system in Black Panther’s Wakanda
Published 2023-04-01“…The emergence of COVID-19 (SARS-CoV-2) has introduced significant global challenges for healthcare systems, healthcare professionals and patients. This current climate creates an opportunity to learn from equitable health systems and move toward making fundamental changes to healthcare systems. …”
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2143
The effects of seismic activities following the 30 October 2020 Samos Island earthquakes in Izmir and its surrounding
Published 2024-12-01“…In this context, in order to determine the current deformation after the Samos Island earthquake that occurred on October 30, 2020, measurements were performed at six continuous GNSS stations in and around Izmir. …”
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2144
Wanderings of the nomadic subject: on becoming, relationality and interdependency as a space of subject's autonomy in education
Published 2024-12-01“…It aims to show the most important theoretical assumptions of contemporary philosophical currents, which create different contexts for rethinking and reconfiguring both discursive and material aspects of human subjectivity, difference, identity, relations between different entities or, finally, practices of producing knowledge and arranging educational reality. …”
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2145
Integrating Palliative Care and Heart Failure: the PalliatHeartSynthesis realist synthesis
Published 2024-09-01“…Our realist analysis developed and refined 6 overarching context–mechanism–outcome configurations and 30 sub context–mechanism–outcome configurations. …”
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2146
Phosphorus has a crucial role in growth performance of calves fed starters with incorporated forage
Published 2025-09-01“…It is concluded that FA to starter diets has a high potential to improve growth performance in young dairy calves. However, currently, recommended dietary P levels of approximately 0.45% may be insufficient to support fiber digestibility, microbial protein synthesis and growth, especially pre-weaning, when forage-containing starters are high in phytate-P.…”
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2147
Establishing priorities for future land conservation to maximise biodiversity conservation and other ecosystem services in the Tilarán Mountains of Costa Rica
Published 2025-04-01“…The opportunity to connect currently protected areas to one another through effective biological corridors still remains, possibly through conservation partnerships with landowners or direct land purchase, but time could be short as increasing development and changing land-use patterns threaten to further isolate habitats in the MAB.…”
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2148
Investigating the Key Factors Influencing the Profitability of Romanian Public Water Supply and Sewerage Services
Published 2025-08-01“…Efficient management of non-revenue water and damage reduction were also found to be key to improve financial performance and increase sustainability. The paper provides an in-depth understanding of market mechanisms and can support the development of more effective public policies for water resource management in the context of current socio-economic and environmental challenges. …”
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2149
Immune‐dysregulation harnessing in myeloid neoplasms
Published 2024-09-01“…We also consider both current and novel therapeutic strategies to restore normal immune system function in the context of myeloid malignancies.…”
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2150
Using MaxEnt modeling to analyze climate change impacts on Pseudomonas syringae van Hall, 1904 distribution on the global scale
Published 2024-12-01“…Pseudomonas syringae is a pathogenic bacterium that poses a significant threat to global agriculture, necessitating a deeper understanding of its ecological dynamics in the context of global warming. This study investigates the current and projected future distribution of P. syringae, focusing on the climatic factors that influence its spread. …”
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2151
Insomnia, Cognitive Impairment, or a Combination of Both, Alter Lipid Metabolism Due to Changes in Acylcarnitine Concentration in Older Persons
Published 2025-06-01“…Results: Our results show that insomnia increases the concentration of acylcarnitines (C10, C8, C14, C12:1, C18:1 and C18) as compared to CI group, while older persons with CI show a decrease the concentration of the acylcarnitines C16, C10 and C8. …”
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2152
Incubation of semen with human follicular fluid improves the antioxidant status and quality of spermatozoa after freezing–thawing
Published 2025-06-01“…Therefore, most studies are currently focused on optimizing this method to achieve high-quality semen after thawing. …”
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2153
Preparation and Characterization of Activated Carbon Made from Robusta Coffee Skin (Coffea Canephora)
Published 2020-10-01“…Indonesia is one of the coffee-producing countries where production tends to increase from year to year. Currently, residuals from coffee-fruit processing such as coffee-skin and husks are thrown away without any use and this biomass residual contains several toxic chemicals such as alkaloids, tannins, and polyphenols. …”
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2154
Investigating The Performance Of Local And Indigenous Businesses In Times Of Economic Recession With Emphasis On Developing The Capabilities Of Cooperatives In Sistan And Baluchest...
Published 2024-12-01“…A more general definition of economic recession is a significant decrease in activity in the entire economy that lasts at least a few months. …”
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2155
Monitoring of hepatitis E virus infection and replication by functional tagging of the ORF2 protein
Published 2025-03-01“…Understanding of the mechanisms underlying productive HEV infection remains incomplete and would benefit from technological advances improving current model systems. Methods: We exploited transposon-mediated random insertion and selection of viable clones to identify sites in the HEV open reading frame 2 (ORF2) protein, corresponding to the viral capsid, allowing for the insertion of reporter sequences in a functional context. …”
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2156
Short Research Report: A universal socio-emotional learning programme for child adjustment and peer relationships
Published 2025-04-01“…Universal SEL interventions have garnered increasing attention in educational systems worldwide, including in Portuguese schools, with short- and long-term benefits for students, such as social and emotional competencies, academic performance, and positive attitudes and behaviours. …”
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2157
Micro nutrients as immunomodulators in the ageing population: a focus on inflammation and autoimmunity
Published 2024-12-01“…For example, it points out the modulatory effects of vitamin D on both innate and adaptive immunity, with a specific focus on its ability to suppress pro-inflammatory cytokines synthesis while enhancing regulatory T-cell function. In the same context, also zinc is described as important nutrient for thymic function and T-cell differentiation but exhibits immunomodulatory functions by decreasing inflammation. …”
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2158
Unlocking the potential of global greenhouse gas mitigation by reducing food loss and waste
Published 2025-06-01“…Food loss and waste (FLW) are significant yet under-addressed contributors to global greenhouse gas (GHG) emissions, and the effectiveness of current FLW mitigation policies and valorization technologies remains insufficiently explored. …”
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2159
Irrigation Water and Security in South African Smallholder Farming: Assessing Strategies for Revitalization
Published 2025-03-01“…This study examines the current water security challenges faced by smallholder farmers in ensuring water security in South Africa. …”
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2160
A methodological framework for assessing development solutions: application to wood fuel challenges in Nigeria
Published 2025-04-01“…Abstract Development interventions often yield co-benefits and trade-offs across multiple Sustainable Development Goals (SDGs). However, current approaches typically assess progress towards specific SDG targets, such as increasing access to clean energy or improving health outcomes, rather than evaluating the co-benefits and trade-offs of the solutions used to achieve these targets. …”
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