Evaluating the climate change robustness of Canadian protected area management plans by Stephanie Barr, Christopher J. Lemieux, Jen Hoesen, Brooklyn Rushton, Pamela Wright

“…Due to these impacts, there is a need for managers to take more robust approaches to considering the implications of climate change on the overall application and efficacy of protected areas management direction, including the achievement of the goals and objectives contained within management plans. Through a systematic and comprehensive content analysis approach, this study assesses the current extent to which climate change is considered in Canadian protected area management plans. …”
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Facial Beauty Prediction Combining Dual-Branch Feature Fusion With a Stacked Broad Learning System by Junying Gan, Hantian Chen, Wenchao Xu, Huicong Li, Zhenxin Zhuang, Zhen Chen

“…Facial beauty prediction (FBP) is a key computer vision task that uses algorithms to assess facial attractiveness. Current models rely on single feature extraction, such as using a single convolutional neural network to extract local feature, failing to capture other potentially more important information contained within facial data and limiting feature diversity. …”
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Scientific and Regulatory Lessons Learnt on Building a Chemistry, Manufacturing, and Controls (CMC) Package for COVID-19 Variant Vaccine Updates in the EU—A Regulator’s Perspective... by Ragini Shivji, Elena Grabski, Veronika Jekerle

“…The pace at which variants emerge challenges the technical feasibility to make adapted vaccines available in a suitable timeframe and in sufficient quantities. Despite the current absence of a clear-cut seasonal spread for COVID-19, the EU regulatory approach thus far is a pragmatic approach following a pathway similar to that of seasonal influenza. …”
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Phylogenetic Groups and Antimicrobial Resistance among Uropathogenic Escherichia coli Isolates from Hospitalized Patients in Tehran by Mana Talebi Farahani, Mohammad Karim Rahimi, Mehdi Goudarzi

“…Background: The presence of Escherichia coli among uropathogens is increasing significantly worldwide. It accounts for a considerable amount of morbidity and high medical costs and also can lead to mortality. …”
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N-Acetyl-cysteine and Mechanisms Involved in Resolution of Chronic Wound Biofilm by Xin Li, Jane Kim, Jiabin Wu, Alaa’ I Ahamed, Yinsheng Wang, Manuela Martins-Green

“…Chronic wounds are a major global health problem with the presence of biofilm significantly contributing to wound chronicity. Current treatments are ineffective in resolving biofilm and simultaneously killing the bacteria; therefore, effective biofilm-resolving drugs are needed. …”
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Non-linear oral bioavailability and clinical pharmacokinetics of high-dose Andrographis paniculata ethanolic extract: relevant dosage implications for COVID-19 treatment by Phanit Songvut, Jaratluck Akanimanee, Tawit Suriyo, Nanthanit Pholphana, Nuchanart Rangkadilok, Duangchit Panomvana, Porranee Puranajoti, Jutamaad Satayavivad

“…These findings suggest that current extraction process of ethanolic extract may hinder its effectiveness. …”
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Stability and change in latent movement behaviour profiles during adolescence and links with future depressive symptoms by Christopher Knowles, Gavin Breslin, Angela Carlin, Kyle Paradis, Stephen Shannon

“…Transition patterns containing a period of minimal movement predicted worse depressive symptoms at ages 18 and 22. …”
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Copper homeostasis and neurodegenerative diseases by Yuanyuan Wang, Daidi Li, Kaifei Xu, Guoqing Wang, Feng Zhang

“…Copper is a potent oxidant that increases reactive oxygen species production and promotes oxidative stress. …”
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TIM-3 teams up with PD-1 in cancer immunotherapy: mechanisms and perspectives by Zhuohong Yan, Chunmao Wang, Jinghong Wu, Jinghui Wang, Teng Ma

“…Among these candidates, T cell immunoglobulin and mucin-domain containing-3 (TIM-3) is considered a promising target. …”
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Spatio-temporal changes of water quality variables in a highly disturbed river by Z. Abdollahi, A. Kavian, S.H.R. Sadeghi

“…Many rivers in developing countries are unhealthy because they contain harmful physical, chemical and biological agents. …”
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Descriptive, analytical and molecular epidemiology of pancreatic cancer by O. V. Shangina, D. M. Maximovich, D. G. Zaridze

“…The purpose of the study was to present current data on the role of lifestyle and heredity factors in the etiology of pancreatic cancer (PC). …”
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Identification of widely conserved biosynthetic gene cluster involved in pigment production of Bacillus subtilis by Rune Overlund Stannius, Christopher A. Dunlap, Estelle Morvan, Mélanie Berbon, Sophie Lecomte, Antoine Loquet, Ákos T. Kovács

“…This study describes the chemical and biological features of a new class of SM BGC, which we hope will serve to improve the current BGC discovery pipelines in Bacilli.IMPORTANCEIdentification of novel microbial secondary metabolites (SMs) and their biosynthetic gene cluster (BGC) has become increasingly difficult, especially in Bacilli, as the tools for screening and genome mining are dependent on clear function or similarity to already known BGCs. …”
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A collaborative approach to advancing research and training in Public Health Data Science—challenges, opportunities, and lessons learnt by Elisha Abade, Wondwossen Mulugeta, Idah Orowe, Getachew Hailemariam, Patrick Weke, Rahel Bekele, Isabelle Zaugg, Jeff Goldsmith, Tiffany Sanchez, Kiros Berhane

“…However, there is a severe lack of well-trained data scientists and home-grown educational programs to enable context-specific training. The lack of human capacity and resources for public health data analysis as well as the dire need to use modern technology for better understanding and possible intervention cannot be dealt with currently available educational programs and computing infrastructure, demanding a great deal of collaboration and investments within Africa and with the Global North This paper describes processes undertaken to establish sustainable research training programs and to train a new generation of data scientists with knowledge, mentoring, professional skills, and research immersion. …”
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A Systematic Review Examining the Association of Falls With Diabetes‐Related Foot Ulcers by Mike Wu, Mallika Sinha, Chanika Alahakoon, Kristen S. Barratt, Shivshankar Thanigaimani, Jonathan Golledge

“…A meta‐analysis showed high heterogeneity between studies (I2 = 95%) and an increased risk of falls in people with DFU (risk ratio 2.25 and 95% CI 1.05–4.84). …”
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A systematic review of serious games as tools for STEM education by Talia Tene, Diego Fabián Vique López, Paulina Elizabeth Valverde Aguirre, Nilo Israel Cabezas Oviedo, Cristian Vacacela Gomez, Stefano Bellucci

“…A total of 37 peer-reviewed journal articles met the inclusion criteria, guided by the PICOS framework, which focused on studies reporting the use of serious games in STEM education contexts. Data extraction included study characteristics, game types, participant demographics, educational contexts, and reported outcomes.AnalysisThe selected studies were analyzed to assess the effectiveness of serious games in enhancing learning outcomes, engagement, and performance in STEM education. …”
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Assessment of the effect of the COVID-19 pandemic on levels of satisfaction in marital relationships during and post-lockdown by Rasha Aziz Attia Salama, Rabab Gad Abd El-Kader, Talaat Matter Tadross, Shaimaa Hashem Elsalous

“…The current study aimed to assess marital satisfaction during and post the lockdown of the COVID-19 pandemic and explore the factors influencing marital satisfaction among the public. …”
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A Strategic Framework for Community Engagement in Oceans and Human Health by Margaret A. Carson, Diane M. Doberneck, Zac Hart, Heath Kelsey, Jennifer Y. Pierce, Dwayne E. Porter, Mindy L. Richlen, Louisa Schandera, Heather A. Triezenberg

“…We illustrate the framework with examples from current COHH case studies and conclude with future directions for strategic community engagement in OHH and other environmental health contexts.…”
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Anticipating how spatial fishing restrictions in EU waters perform to protect marine species, habitats, and dependent fisheries by François Bastardie, Amaia Astarloa, Logan Binch, Isabella Bitetto, Dimitrios Damalas, Jochen Depestele, Pierre-Yves Hernvann, Sigrid Lehuta, Jonas Letschert, Irida Maina, Stéphanie Mahévas, Georgia Papantoniou, Miriam Püts, Giovanni Romagnoni, Giovanni Romagnoni, Giovanni Romagnoni, Giovanni Romagnoni, Maria Teresa Spedicato, Klaas Sys, Irini Tsikopoulou, Gert Van Hoey, Walter Zupa, Anna Rindorf

“…As the proportion of closed regions increases, potential effects on marine ecosystems can even be damaging in the short term to some sensitive species (such as the endangered, threatened and protected species ETP) and vulnerable habitats (with currently high relative benthic status RBS). …”
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Changes in the structure and properties of graphene oxide surfaces during reduction and modification by M. T. Kartel, K. V. Voitko, Y. Grebelna, S. V. Zhuravskyi, K. Ivanenko, T. V. Kulyk, S. M. Makhno, Yu. I. Sementsov

“… The aim of the current study was to find changes in the structure and state of the surface of graphene oxide (GO) under the conditions of its reduction and modification by hetero atoms of nitrogen and amino acids. …”
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Systematic review and network meta-analysis on the efficacy and safety of parmacotherapy for hand osteoarthritis. by Ruiqi Wu, Qinglin Peng, Weiwei Wang, Jixian Zheng, Yi Zhou, Qipei Yang, Xuan Zhang, Hongyu Li, Lin Meng

“…Tailored treatment decisions based on individual contexts are imperative.…”
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