MECHANISMS FOR ENSURING THE ECONOMIC DEVELOPMENT OF RURAL AREAS THROUGH THE FORMATION OF THEIR ENERGY DEPENDENCE BASED ON THE INTENSIFICATION OF BIOFUEL PRODUCTION by Yuliia Okhota, Denys Titov, Svitlana Dotsiuk

“…To achieve this goal, the article discusses the theoretical aspects of energy independence, analyzes current practices of biofuel production, and provides recommendations for their further implementation. …”
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Towards a sustainable rare disease and orphan drug ecosystem in Saudi Arabia: policy insights from a multi-stakeholder workshop by Ghada Mohammed Abozaid, Ghada Mohammed Abozaid, Hussain Abdulrahman Al-Omar, Abdulaziz Alrabiah, Asma AlMuaither, Amy Jayne McKnight

“…Through a series of presentations, educational sessions, and plenary discussions, participants examined the current landscape of RDs in SA, identified barriers to accessing ODs, and recommended strategies and initiatives to improve the accessibility, innovation, and sustainability of ODs.ResultsThe workshop highlighted key challenges recognized by a diverse group of 59 participants, including the absence of a national strategy, absent of local RDs and ODs definitions in the Saudi context, limited awareness and understanding of RDs among healthcare professionals, delayed diagnoses, scarcity of treatment and diagnosis centers for RDs, insufficient screening and prevention programs, regulatory hurdles in approving and importing ODs, and financial constraints. …”
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Intravesical instillation-based mTOR-STAT3 dual targeting for bladder cancer treatment by Dae Hoon Lee, Jung Ki Yoo, Ki Hwan Um, Wootae Ha, Soo Min Lee, Junseong Park, Min Jeong Kye, Jungyo Suh, Jin Woo Choi

“…Graphical Abstract The current investigation introduces an innovative conceptualization of bispecific short hairpin RNA (bs_shRNA) tailored for the equilibrated modulation of dual genes within a singular cellular context. …”
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Knowledge of Preconception Healthcare and Associated Factors: A Study among Mothers in Jinka Town, Southern Region, Ethiopia by Kassahun Fikadu Tesema, Tamirat Cheneka, Alemayehu Alemu, Mekonen Feyissa, Birhanu Birkaye, Hafiza Mohammed, Eleni Kidu, Getahun Wegaso, Biresaw Wasihun

“…Preconception healthcare is promising to improve the reproductive health status of women and couples if they receive care three months to two years before conception. In the current context of Ethiopia, however, preconception healthcare is overlooked in the continuum of care. …”
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Propagation Characteristics of Multi-Cluster Hydraulic Fracturing in Shale Reservoirs with Natural Fractures by Lianzhi Yang, Xinyue Wang, Tong Niu

“…Understanding the effects of reservoir and fracturing conditions on fracture propagation is of great significance for optimizing the hydraulic fracturing process and has not been adequately explored in the current literature. In the context of shale reservoirs in Yibin, Sichuan Province, China, the study selects outcrops to prepare samples for uniaxial compression and Brazilian splitting tests. …”
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Significant fundamental translational research on breast cancer in China: progress and prospects by LU Yufeng, WANG Han, XIE Yifan, JIANG Yizhou, SHAO Zhimin

“…Breast cancer is the most prevalent malignant tumor that poses a threat to women's health in China, with incidence and mortality rates persistently increasing. Given this critical situation, there is an urgent need to optimize therapeutic options through basic translational research to address current treatment challenges. …”
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Research Progress on the Impact of Nighttime Outdoor Environments on Residents’ Health by Chongxian CHEN, Xinrui XIONG, Guangsi LIN, Jingyi LIU

“…As research in this area continues to expand, there is an urgent need to synthesize existing knowledge, identify current limitations, and provide guidance for future investigations. …”
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Corrosion Performance of Chemically Passivated and Ion Beam-Treated Austenitic–Martensitic Steel in the Marine Environment by Viktor Semin, Alexander Cherkasov, Konstantin Savkin, Maxim Shandrikov, Evgeniya Khabibova

“…Immersion for 140 h in a solution containing 0.05 M potassium dichromate and 10% phosphoric acid promotes formation of chromium hydroxides in the outer surface layer. …”
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“If that would have lessened my symptoms, that would have been great...”: a qualitative study about the acceptability of tecovirimat as treatment for mpox by Sara Paparini, Rosalie Hayes, Benjamin Weil, Will Nutland, Ismael Maatouk, Teodora Wi, Chloe M. Orkin, Rosamund Lewis

“…Conclusions This exploratory study suggest that offering tecovirimat (or comparable emergency-licensed treatments) to people with mpox is acceptable, although uptake will depend on knowledge of mpox treatment options, trust in medicine and medical professionals and provision of relevant information and choice. To increase acceptability of such treatments, clinicians should ensure patients are aware of mpox symptom management options, including pain relief; acknowledge and address patient concerns upfront and within the context of non-stigmatising care; and communicate offers in a consistent and supportive manner in line with locally approved eligibility criteria and protocols at the time.…”
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Analyzing Waste Policy-Making from the Perspective of Local People in the Selected Villages of Kermanshah County by Parvin Rezaeibavandpour, Mohammad Akbarpour

“…AbstractThe increase in waste production and the associated ecological concerns have made waste management policy critically important. …”
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Effectiveness of AdaBoost and XGBoost Algorithms in Sentiment Analysis of Movie Reviews by I Gusti Ayu Nandia Lestari, Ni Made Rai Masita Dewi, Komang Gita Meiliana, I Komang Agus Ady Aryanto

“…Currently there are many entertainment platforms that provide various movies, TV shows, games, and other content. …”
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Contact Lenses in Pediatric Ophthalmological Practice by E. Yu. Markova, E. A. Perfilyeva

“…Currently, the indication for contact lenses use in children are the same as for the adults (with certain specific and limitations). …”
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Numerical Analysis of Leakage and Diffusion Characteristics of In-Situ Coal Gas with Complex Components by Enbin Liu, Lianle Zhou, Ping Tang, Bo Kou, Xi Li, Xudong Lu

“…Currently, the area of consequence of the harm caused by a leak in a gathering pipeline transporting in-situ coal gas has not been clarified. …”
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Analysis of Factors Influencing the Development of Community-Based Tourism in Rural Areas, Case Study: Villages Targeted by Tourism in the Markazi Province by Hamid Afshari, Behrouz Mohammadi Yeganeh, Hossein Farahani, Mehdi Cheraghi

“…In the socio-cultural dimension, it should be said that there is a strong relationship between cultural sustainability and participation, and the local community is very vulnerable to the indiscriminate and unprincipled increase in tourism. The results of the current research showed that due to the lack of correct and principled planning in all dimensions, including the cultural dimension, the participation of the local community in tourism was very small. …”
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Consequences, costs and cost-effectiveness of workforce configurations in English acute hospitals by Peter Griffiths, Christina Saville, Jane Ball, David Culliford, Jeremy Jones, Francesca Lambert, Paul Meredith, Bruna Rubbo, Lesley Turner, Chiara Dall’Ora

“…These findings lend support to policy initiatives aimed at increasing the supply of RNs. Study registration This study is registered as Current Controlled Trials ClinicalTrials.gov NCT04374812. …”
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Pharmaceutical Providing for Prevention and Treatment of Influenza in Children by Olіynyk O., Kіrda І., Voitsekhivska I.

“…The mortality rate of uncomplicated influenza is 0.01-0.2 %, but it increases sharply in the case of illness in frail persons and young children. …”
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Validated UHPLC Methods for Melatonin Quantification Reveal Regulatory Violations in EU Online Dietary Supplements Commerce by Celine Vanhee, Cloë Degrève, Niels Boschmans, Yasmina Naïmi, Michael Canfyn, Eric Deconinck, Marie Willocx

“…Moreover, 12% of legal supply chain samples violated current legislation through unauthorized health claims or contained at least triple the melatonin amount permitted in Belgium. …”
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Oxidation behaviour of Ti-V-Cr-Nb-Ta and Al-Ti-V-Cr-Ta refractory high entropy alloys: Effects of Nb and Al substitutions by Kieran Rivers, Bradley Young, Yuanbo T. Tang, Bo-Shiuan Li, Angus J. Wilkinson, David E.J. Armstrong, Junliang Liu

“…However, a significant issue with current RHEAs is that those exhibiting good mechanical properties tend to show poor oxidation resistance, and vice versa. …”
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Emergency Care for Suicidal Behavior Before and During the COVID-19 Pandemic in Two Hospitals in Bogotá: a Longitudinal Analysis by Gutiérrez-Dajud, Sasha Stefany, Pastran-Cortés, Ana María, Mendivelso, Fredy, Rodríguez-Bedoya, Ingrid Milena, Moreno-Gómez, Jairo Enrique, Muñoz-Tamayo, Rodrigo

“…Suicidal ideation was the most documented typology during the pandemic (p <0.001), and the prevalence of suicidal behavior among children and adolescents (≤18 years) increased from 29% to 33%. Conclusions: Theresults suggest that the pandemic catalyzed the number of admissions for suicidal behavior in the general population after the implementation of containment measures or contagion prevention restrictions. …”
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A pilot study on physiological relaxation and enhanced work performance by volatile organic compounds emitted from Kagawa hinoki (Chamaecyparis obtusa) interior walls by Fumi Kishida, Kazuki Tani, Taisuke Nakashima, Fadilla Zennifa, Akiko Isa, Noboru Fujimoto, Koki Fujita, Ryuma Taki, Hiroo Yasutomi, Naotoshi Yasumori, Kuniyoshi Shimizu

“…This timber was reported to have a relaxing effect toward the participants, and this study discovered that inhaling air containing VOCs emitted by Kagawa hinoki interior walls increased parasympathetic nervous activity during resting periods between arithmetic tasks. …”
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