M.A.R.V.E.L.S. "Medical Students Advancing Research, Visibility, Education, Leadership, and Support." A Student-Driven Initiative by Molly Mehta, Kayvon Yazdanbakhsh, Elizabeth Hsu, Olga Gomeniouk, Kayla Nenninger, Devin P. Asher

“…METHODS: A committee of six second-year medical students and four faculty advisors established three networks to increase medical student involvement in research. The first is a Microsoft systems database containing contact, field of study, productivity, and project information of research faculty open to mentoring students aimed to facilitate meaningful collaboration between faculty seeking help with research projects and medical students eager to conduct research. …”
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Rapid public health genomics capacity building during the COVID-19 Delta crisis driven by a transnational private, public, and social alliance by Mehul Champaklal Mehta, Mehul Champaklal Mehta, Mehul Champaklal Mehta, Gayatri Nair Lobo, Gayatri Nair Lobo, Gretchen Weightman, Gretchen Weightman, Vidushi Chitalia, Vidushi Chitalia, Jayanthi Shastri, Jayanthi Shastri, Jayanthi Shastri

“…This has transformed Mumbai’s ability to expeditiously identify and contain infectious outbreaks, thus better protecting its citizens. …”
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Contribution of the TRPM4 Channel to Osteogenic Differentiation of Human Aortic Valve Interstitial Cells by Margaux Aize, Arthur Boilève, Benoit D. Roussel, Laura Brard, Harlyne Mpweme Bangando, Corentin Kerevel, Alexandre Lebrun, Hind Messaoudi, Vladimir Saplacan, Alain Manrique, Romain Guinamard, Christophe Simard

“…Results Western blot on VICs revealed TRPM4 protein expression and channel functionality was confirmed by patch‐clamp recordings exhibiting a cationic current sensitive to voltage and internal Ca2+. VICs maintained in pro‐calcifying media exhibited a higher mineralization than in standard media, with an increase in osteogenic markers. …”
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Study on the Preparation and Corrosion Properties of Hydrotalcite Composite Permeation Layer via Plasma Electrolytic Carbonitriding by YANG Zhuolin, ZHAI Yanbo, CENG Shunke, PENG He, LE Chunpeng, WEI Ziwei

“…In order to improve the corrosion resistance of steel materials treated by plasma electrolytic infiltration，annealed 20 steel was used as the experimental substrate.Micro-nanopores formed during the plasma electrolytic carbonitriding process were utilized as containers to load magnesium-iron layered double hydroxides (Mg-Fe-LDHs) as a corrosion inhibitor，and the effects of Mg-Fe-LDHs on the corrosion performance of 20 steel were investigated.First，formamide was used as the carbon and nitrogen source，and KCl was used as the conductive salt.These components were mixed with deionized water to form an electrolyte.Then，the samples were treated at a constant DC pulse voltage of 220 V for 9 min to produce a carbonitrided layer (denoted as PEC/N samples).Subsequently，the PEC/N samples were immersed in a Mg-Fe-LDHs precursor solution containing urea，MgSO4 and Na2CO3，and hydrothermally crystallized at 140 ℃for 10 h to obtain a composite infiltration layer (denoted as PEC/N-LDHs samples).The performance of the composite infiltration layers was analyzed using a microhardness tester，scanning electron microscopy (SEM)，X-ray diffraction (XRD) and electrochemical testing.Results showed that the microhardness of the composite infiltration layer reached approximately 900 HV，which was 4.6 times higher than that of the substrate.The carbonitrided layer of the PEC/N samples was about 20 μm，with a smooth and flat cross-section but a rough，porous and honeycomb-like surface.After hydrothermal synthesis of LDHs，the surface became smooth，lacking a visible honeycomb structure，and a large number of flake-like crystalline deposits appeared on the surface.The XRD spectra of the PEC/N samples showed absorption peaks corresponding to Fe3C，Fe5C2，α-Fe and Fe3N phases.After the in-situ loading of Mg-Fe-LDHs，new absorption peaks corresponding to the (003)，(006) and (009) crystal planes of Mg-Fe-LDHs appeared in the XRD spectra of the PEC/N-LDHs samples.Combined with SEM morphology analysis，it was confirmed that Mg-Fe-LDHs were successfully loaded，presenting a flake-like structure.Compared with 20 steel，the PEC/N samples exhibited improved corrosion potential (Ecorr) and corrosion current density (Jcorr)，reaching－0.451 V and 75.22 μA/cm2，respectively，although the lowfrequency impedance modulus (｜Z ｜0.01 Hz) showed no significant increase，reaching only 998.5 Ω·cm2.After loading Mg-Fe-LDHs，the PEC/N-LDHs samples demonstrated further improvements，with Ecorr，Jcorr and ｜Z ｜0.01 Hz reaching－0.355 V，39.11 μA/cm2 and 6 586.0 Ω·cm2，respectively，showing significant enhancement compared to both 20 steel and PEC/N samples.These results indicated that plasma electrolytic carbonitriding treatment of 20 steel could produce a carbonitrided layer with high hardness.Additionally，the hydrothermal loading of LDHs further improved the corrosion resistance of the composite infiltration layer without affecting its hardness.The PEC/N-LDHs composite infiltration layer thus achieved both high hardness and superior corrosion resistance.…”
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Immune status changes in patients with phlegmon in the maxillofacial region relation with purulent process prevalence by N. G. Barannik, S. D. Varzhapetyan, A. V. Sidoryako, Yu. S. Karabinova

“…Serum IL4 concentration was increased only in patient with pyoinflammatory changes in more than one area. …”
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The possibility of using the DKS-AT1123 dosimeter for radiation monitoring of medical electron accelerators with the energy of more than 10 MeV by A. N. Barkovsky, S. A. Ogorodnikov

“…Over the past 4 years, their number has increased 2.5 times. These installations contain pulsed electron accelerators that generate pulsed bremsstrahlung radiation with a maximum energy from 6 to 21 MeV. …”
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Novel Nanozyme-Based Multicomponent in situ Hydrogels with Antibacterial, Hypoxia-Relieving and Proliferative Properties for Promoting Gastrostomy Tube Tract Maturation by Xiao F, Yan B, Yuan T, He Y, Zhang X, He X, Peng W, Xu Y, Cao J

“…The antibacterial efficiency of the MO-HPA1.0 group on E. coli and S. aureus increased by about 40.1% and 55.6% respectively, compared to the MO-HPA0.5 group. …”
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Low miR-936-mediated upregulation of Pim-3 drives sorafenib resistance in liver cancer through ferroptosis inhibition by activating the ANKRD18A/Src/NRF2 pathway by Xiao Li, Mengna Cui, Long Xu, Qie Guo

“…ObjectiveSorafenib, a multikinase inhibitor, is currently the standard treatment for advanced liver cancer. …”
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Design and Synthesis of Bis-Chalcones as Curcumin Simplified Analogs and Assessment of Their Antiproliferative Activities Against Human Lung Cancer Cells and <i>Trypanosoma cruzi</... by Gabriela Alves de Souza, Lorrane de Souza Chaves, Afonso Santine M. M. Velez, Jorge Lucas F. Lacerda, Paulo Pitasse-Santos, Jayane Clys Conceição dos Santos, Otávio Augusto Chaves, Carlos Serpa, Raphael do Carmo Valente, Leonardo Marques da Fonseca, Marcos André Rodrigues da Costa Santos, Jhenifer Santos dos Reis, Carlos Antônio do Nascimento Santos, Lucia Mendonça-Previato, Jose Osvaldo Previato, Celio Geraldo Freire-de-Lima, Debora Decoté-Ricardo, Leonardo Freire-de-Lima, Marco Edilson Freire de Lima

“…<b>Background: </b>Anticancer therapies represent the primary treatment option for a significant number of cancer patients globally; however, many of these treatments are associated with severe side effects as they target molecular structures present in both cancerous and healthy cells. In a similar context, the treatment of Chagas disease, a neglected tropical illness, is hindered by the high toxicity of the currently available drugs. …”
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Direct oral penicillin challenge in secondary care with low-risk patients: the SPACE mixed-methods study with cost-effectiveness analysis by Mamidipudi Thirumala Krishna, Yogini H Jani, Iestyn Williams, Ruben Mujica-Mota, Rebecca Bestwick, Michele Siciliano, Robert Michael West, Rashmeet Bhogal, Bee Yean Ng, Kornelija Kildonaviciute, Rachel Pollard, Nicola Jones, Louise Dunsmure, Mairead McErlean, Neil Powell, Chidanand C Hullur, Ariyur Balaji, Jonathan Sandoe, Amena Warner, Ron Daniels, Caroline Thomas, Siraj A Misbah, Louise Savic

“…To explore practical aspects of implementing this de-labelling programme in secondary care by investigating factors, such as organisational context, treatment pathway, protocol implementation, time taken and resources. …”
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Neutralizing Antibody Spectrum in COVID-19 Patients who Became Ill During the Circulation of Different SARS-CoV-2 Variants by S. K. Pylaeva, L. I. Kozlovskaya, A. A. Erovichenkov, D. I. Sirazova, E. Y. Shustova, E. A. Artamonova, A. A. Sinyugina, I. V. Gordeychuk, D. V. Troshyanskiy, E. V. Kosareva, O. N. Solodovnikova, R. K. Kogotyzhev, A. U. Berestovskaia, I. N. Tyurin, D. N. Protsenko, A. A. Ishmukhametov

“…Thus, a fraction of people, regardless of age, who became infected in 2020-2021 have an antibody spectrum capable of neutralizing current and possibly related SARS-CoV-2 variants that will emerge in the near future. …”
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Life cycle assessment of polyethylene packaging and alternatives on the European market by Manfred Tacker, Tasja Hafner-Kuhn, Andrin Gstöhl, Experience Nduagu, Eric Vozzola, Timothee W. Roux, Rafael Auras

“…The assessment covered the material and production phase to end-of-life (EoL), based on current conditions in Europe (EU27 + UK). The potential impacts from the packaged product's production and usage phase were excluded. …”
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Improving the charge transport of perovskite nanocrystal light-emitting-diodes through Benzylammonium ligand exchange by Minsik Gong, Dong Gyu Lee, Gwang Yong Shin, Yun Seop Shin, Donghwan Yun, Yunhye Jeong, Sang Wook Park, Chan Beom Park, Yung Jin Yoon, Sung Yong Bae, Yun-Hi Kim, Jin Young Kim, Tae Kyung Lee, Gi-Hwan Kim

“…As results, the LHP LEDs using these ligand-exchanged LHP NCs, achieving a notable increase maximum current efficiency (CEmax,) to 5.88 %, 19.5 cd A-1 at BA bromide, and 5.50 %, 16.6 cd A-1 at BA chloride, compared to devices using pristine LHP NCs, which achieved external quantum efficiency (EQE) 2.4 %, CEmax 7.8 cd A-1.…”
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Mechanisms of hepatic dysfunction in Nile tilapia (Oreochromis niloticus) fed a high-fava bean (Vicia faba L.) diet by Xinyao Zhang, Ke Cheng, Lixue Dong, Dexing Zhu, Qingyong Li, Zhongbao Guo, Yongju Luo, Apeng Liu, Juan Tian, Di Peng, Jianmin Zhang, Yangyang Liu, Hua Wen, Ming Jiang

“…Fava bean is currently utilized as a specialized feed ingredient to enhance the muscle texture of fish. …”
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Harnessing Facebook to Investigate Real-World Mentions of Adverse Events of Glucagon-Like Peptide-1 Receptor Agonist (GLP-1 RA) Medications: Observational Study of Facebook Posts F... by Amrutha S Alibilli, Vidur Jain, Heran Mane, Xiaohe Yue, Alexandria Ratzki-Leewing, Junaid S Merchant, Shaniece Criss, Quynh C Nguyen, Rozalina G McCoy, Thu T Nguyen

“… Abstract BackgroundIn recent years, there has been a dramatic increase in the popularity and use of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) for weight loss. …”
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Transmission network and phylogenetic analysis reveal older male-centered transmission of CRF01_AE and CRF07_BC in Guangxi, China by Fei Zhang, Yao Yang, Na Liang, Huayue Liang, Yongzheng Chen, Zhaosen Lin, Tongbi Chen, Wenling Tan, Yuan Yang, Rongye Huang, Lin Yao, Fuling Chen, Xingzhen Huang, Li Ye, Hao Liang, Bingyu Liang

“…In China, the number of newly reported HIV infections in older people is increasing rapidly. However, clear information on the impact of older people on HIV transmission is limited. …”
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Effects of temporary erosion control blanket and grass cover on the rates of runoff and sediment in the cut and fill slopes of forest roads using a rainfall simulation test by Behnaz Askari, Mehran Nasiri, Majid Lotfalian

“…The use of erosion control blankets is a soil bio-engineering method that can effectively reduce runoff and sediment and increase slope stability. Therefore, the current research aimed to temporarily stabilize soil using protective covering treatments, such as jute, straw, wood chips, Festuca grass cover, and nano zeolite super absorbent, to reduce the amount of runoff and sediment. …”
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Multi-method evaluation of volatile flavor compounds in five kiwifruit varieties by ZENG Shuo, GUO Xinyu, NIU Dongsheng, LI Feng

“…[Objective] Fruit wine, as a food of fruit processing, not only enhances the flavor diversity of kiwifruit but also increases its biological activity, leading to the production of kiwifruit wine with a unique flavor, combined fruit with wine aromas, and rich nutrition. …”
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The Characteristics of Chitosan Derived from Lobster Shells and its Effect on Fungi Activity and Water Stability of Lobster Pellets by Muhsinul Ihsan, Ali Harris, Mukminah, Megawati, Nining Purwati, Handa Muliasari, Bayu Priyambodo, Clive Jones, Leo Nankervis

“…Abstract Tropical rock lobster aquaculture is a lucrative industry that is currently limited by the lack of appropriate formulated feed. …”
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The most common errors in automatic ECG interpretation by Krzysztof Kraik, Krzysztof Kraik, Irena Anna Dykiert, Irena Anna Dykiert, Joanna Niewiadomska, Joanna Niewiadomska, Marta Ziemer-Szymańska, Karolina Mikołajczak, Karolina Mikołajczak, Mikołaj Kreń, Mikołaj Kreń, Piotr Kukiełka, Piotr Kukiełka, Adrian Martuszewski, Adrian Martuszewski, Tomasz Harych, Rafał Poręba, Paweł Gać, Małgorzata Poręba

“…Results of our studies should increase the caution among clinicians not to rely fully on the automated analysis. …”
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