Hybrid closed-loop systems for managing blood glucose levels in type 1 diabetes: a systematic review and economic modelling by Asra Asgharzadeh, Mubarak Patel, Martin Connock, Sara Damery, Iman Ghosh, Mary Jordan, Karoline Freeman, Anna Brown, Rachel Court, Sharin Baldwin, Fatai Ogunlayi, Chris Stinton, Ewen Cummins, Lena Al-Khudairy

“…Current prices suggest that HCL is around an annual average of £1500 more expensive than CSII + CGM, although this may increase by around a further £500 for some systems. …”
Get full text

Research progress on nanotoxicity and detoxification of cobalt in metal-based implants by Wentao Fan, Mingxin Guo

“…While mechanisms are increasingly understood, further research is crucial to fully elucidate the long-term systemic consequences and to develop effective clinical detoxification and preventative strategies for patients with cobalt-containing implants.…”
Get full text

ISSUES AND TRENDS OF PROGRESS TOWARDS SUSTAINABLE DEVELOPMENT GOALS IN ROMANIA by Dumitru Florin FRONE, Simona FRONE

“…Monitoring SDG 12 in an EU context focuses on progress made in decoupling environmental impacts from economic growth, in decreasing energy consumption and in tackling waste generation and management. …”
Get full text

Ozonation of 4-aminotoluene as a new method of synthesis of 4-aminobenzaldehyde – an intermediate for the production of anti-tuberculosis drugs by A. H. Halstian, A. S. Вushuiev, Ye. Yu. Vasylenko

“…Continuous control of the current ozone concentration and recording the results in the form of a kinetic curve was carried out when passing ozone-containing gas through the container of the spectrophotometer “SF-46 LOMO” at a certain wavelength of a monochromatic light source. …”
Get full text

The Adaptability of Salicornia bigelovii to Salinity and Nutrient Levels in Aquaculture Effluent by Saisai CHI, Qiufen LI, Zijun LUO, Bo SUN, Wenjie TIAN, Ying MA, Zhiguo DONG, Zhengguo CUI

“…Therefore, the effective treatment and resource utilization of aquaculture effluents have become urgent considerations. The current methods for treating aquaculture effluents include physical, chemical, and biological approaches. …”
Get full text

Mechanical Load‐Induced Upregulation of Talin2 through Non‐Canonical Deubiquitination of OTUB1 Drives Facet Joint Osteoarthritis Pathogenesis by Yizhen Huang, Heng Sun, Haojie Chen, Xiangpeng Wang, Junduo Zhao, Yang Jiao, Hongyi Zhou, Haoyu Cai, Jiafeng Dai, Xuan Huang, Weiyun Chen, Jianxiong Shen

“…Abstract Facet joint osteoarthritis (FJOA) is a prevalent degenerative condition in the aging population; however, the underlying pathophysiological mechanisms remain poorly understood and current therapeutic strategies remain limited to palliative pain management. …”
Get full text

Hygienic requirements to the design of the positron-emission tomography centers and departments by O. V. Minonenko, T. B. Baltrukova, N. S. Bashketova, G. A. Gorskiy, T. V. Kryukova, E. A. Fedorova

“…The aim of the current study is to provide a critical analysis of the current hygienic requirements to the design of the PET, PET/CT and PET/MRI centers and departments. …”
Get full text

The long-term suitability of agrivoltaics as a climate adaptation strategy in the southwestern United States by Talitha H. Neesham-McTiernan, Greg A. Barron-Gafford

“…We evaluate land suitability for agrivoltaics across the southwest using spatially explicit multi-criteria decision analysis, which incorporates biophysical variables that relate to the potential microclimate benefits provided by agrivoltaics under current and future climate conditions. Results show 310,393 km2 of the region is suitable for agrivoltaics, with 20,576 km2 classified as most suitable under current conditions, increasing to 31,712 km2 under 2080 conditions. …”
Get full text

Multi-omics reveals total flavones from Abelmoschus manihot (L.) Medik. [Malvaceae] ameliorate MAFLD via PI3K/AKT/mTOR-mediated autophagy by Chao Lv, Chao Lv, Chao Lv, Chao Lv, Chao Lv, Lei Zhao, Jiani Hou, Hongyin Sun, Hongyin Sun, Hongyin Sun, Zhongsha Li, Zhongsha Li, Zhongsha Li, Zhongsha Li, Yuesong Wu, Yuesong Wu, Yuesong Wu, Yuesong Wu, Peizheng Shi, Yaping Xiao, Yunjin Xie, Yunjin Xie, Yunjin Xie, Yunjin Xie, Wei Su, Wei Su, Wei Su, Wei Su, Mingzhu Yin, Mingzhu Yin, Mingzhu Yin, Mingzhu Yin

“…In MAFLD mice, TFA treatment significantly decreased body weight gain, hepatic lipid accumulation, and the serum levels of ALT, AST, TC, and TG. …”
Get full text

Dietary Passion Fruit Seed Oil Supplementation for Health and Performance of Laying Hens by Laís Garcia Cordeiro, Paola Aparecida Damázio Rodrigues, Gabrieli Andressa de Lima, Elis Omar Figueroa Castillo, Joyce Andrade da Silva, Júlia de Lima Lopes, Anna Luísa Lang, Samir Moura Kadri, Antônio Celso Pezzato, José Roberto Sartori

“…Passion fruit seed oil (PFSO) is rich in bioactive compounds, which can enhance laying hens’ health and performance. The current study was conducted to investigate the effect of increasing PFSO supplementation in laying hens’ productive performance, egg quality, relative weight and length of organs, plasma lipid oxidation, antioxidant status, and gene expression of SOD, GPx, CAT, and NRF2 in the liver. …”
Get full text

LRRC8A in endothelial cells contributes to the aberrant blood-brain barrier integrity in ischaemic stroke by Yan Wang, Yan Zhang, Chang Liu, Xiaoyu Zhang, Bo Wang, Yue Kong, Hailin Zhang, Yanfei Tian, Yupeng Zhao, Zhenghui Wu, Huaxing Zhang, Xiaona Du, Huiran Zhang

“…Background The increased permeability of the blood-brain barrier (BBB) is a critical contributor to the high mortality following ischaemic stroke. …”
Get full text

Exploration of the breast ductal carcinoma in situ signature and its prognostic implications by Jiao Zhang, Hui Lin, Lei Hou, Hui Xiao, Xilong Gong, Xuhui Guo, Xuchen Cao, Zhenzhen Liu

“…A unique six‐gene signature (containing GAPDH, CDH2, BIRC5, NEK2, IDH2, and MELK) was developed for DCIS prognostic prediction. …”
Get full text

Blend of low cost electrode material for energy storage device under DC glow discharge plasma exposed ESAC by Vijayalakshmi K.A, Judith Fennila, K T Maheswari

“…More oxygen-containing functional groups are present, according to an FTIR analysis. …”
Get full text

An analysis of McMurdo Dry Valleys’ lotic habitats within Antarctica’s protected area network and addressing gaps in biodiversity protection by Anna Wright, Cassandra Brooks, Michael Gooseff, Adrian Howkins, Stephen Chignell

“…However, with sustained human presence within the MDV, increasing human activity across Antarctica, and aquatic ecosystems subject to environmental change, the effectiveness of current protections for biodiversity conservation requires evaluation. …”
Get full text

Synthesis of magnetite nanoparticles using electrochemical oxidation by Ye. Ya. Levitin, I. D. Roy, O. S. Kryskiv, T. M. Chan

“…To intensify the anodic process it is necessary to apply the mixing that reduces the thickness of the diffusion layer near the electrode and allows oxidation at a current density of 0.7-1.2 A/dm2. Under appropriate conditions of electrolysis (high current density of the cathode, acidification of the solution) loss of iron Fe2+ is avoided at the expense of cathodic discharge, as mainly at the cathode the reducing of cations H+ occurs. …”
Get full text

Nitrofurans for External Use (Review) by A. V. Beliatskaya, I. M. Kashlikova, А. O. Elagina, I. I. Krasnyuk (jr.), I. I. Krasnyuk, O. I. Stepanova

“…Aspects of the use of nitrofurans for external use (nitrofural, furazolidone and furazidin) are described in the article. Review of current research that is dedicated to development of drugs containing nitrofuran derivatives has been carried out. …”
Get full text

The implementation of Safety Management Systems in healthcare: a systematic review and international comparison by Zhivko Zhelev, Sian de Bell, Alison Bethel, Maria Clarke, Rob Anderson, Jo Thompson Coon

“…Potentially avoidable hospital deaths (out of all hospital deaths) decreased by 53% from 5.5% (95% CI 4.5% to 6.6%) in 2008 to 2.6% (95% CI 2.0% to 3.4%) in 2011–2. …”
Get full text

Ozonolytic synthesis of 2-hydroxybenzyl alcohol for the production of gastrodin by A. H. Halstian, A. S. Hasanova, H. V. Tarasenko

“…Continuous monitoring of the current concentration of ozone, with the recording of the analysis results in the form of a kinetic curve, was carried out when ozone-containing gas passed through the curette at a certain wavelength of a monochromatic light source. …”
Get full text

Stochastic Method of Discounted Cash Flows by A. A. Solodov

“…It is noted that this growth is calculated in relation to the first forecast period, which itself may contain errors, and it is determined only by consumer preferences. …”
Get full text

Umbilical Cord Blood Collection Protocol and the Impact on the Nucleated and Progenitor Cell by Eze, Evelyn Mgbeoma*', Jacob, Ransom Baribefii '., Lenox-Prince, Tamunonengiye-Ofori’ and Okoye, Nelyn Akunna’

“…Inall cases the loss of cells increased with the number of days of storage before processing.…”
Get full text