Oral vs. Outpatient Parenteral Antimicrobial Treatment for Infective Endocarditis: Study Protocol for the Spanish OraPAT-IE GAMES Trial by Guillermo Cuervo, Marta Hernández-Meneses, Arístides de Alarcón, Rafael Luque-Marquez, María M. Alonso-Socas, Ana López-Lirola, Víctor González-Ramallo, Ane J. Goikoetxea-Agirre, David Nicolás, Miguel A. Goenaga, Esperanza Merino, Francesc Escrihuela-Vidal, Pilar Martín-Dávila, Belén Loeches, Lucía Boix-Palop, Oriol Gasch, Marta Camprecios, Alicia Hernández-Torres, Lara García-Álvarez, Marcos Pajarón, María Angels Ribas, Rosa Blanes-Hernández, Inmaculada López-Montesinos, Luis E. López-Cortés, Bárbara Vidal, Mariana Fernández-Pittol, Dolores Navarro, Asunción Moreno, Coral Sala, Juan Ambrosioni, José M. Miró, OraPAT-IE GAMES Investigators

“…Conclusion In a global context of limited healthcare resources and a sustained increase in elderly and frail patients, it is of great importance to demonstrate the effectiveness and safety of outpatient management strategies that could reduce the duration of conventional hospitalizations with their potential complications and inherent costs. …”
Get full text

Contextual Vulnerability Should Guide Fair Subject Selection in Xenotransplantation Clinical Trials by Gianna Strand

“…This paper describes the current transplant system’s use of subjective evaluation criteria, particularly psychosocial support and compliance. …”
Get full text

Helminth Coinfections Modulate Disease Dynamics and Vaccination Success in the Era of Emerging Infectious Diseases by Brice Armel Nembot Fogang, Linda Batsa Debrah, Michael Owusu, George Agyei, Julia Meyer, Jonathan Mawutor Gmanyami, Manuel Ritter, Kathrin Arndts, Derrick Adu Mensah, Tomabu Adjobimey, Achim Hörauf, Alexander Yaw Debrah

“…Helminth infection can also negatively impact vaccine efficacy by suppressing B cell activity, reducing antibody levels, and decreasing vaccine effectiveness against infectious diseases. …”
Get full text

The Validity of Cryptocurrency Transactions and the Analysis of Associated Disputes by Hossein Qahari, Javad Hosseinzadeh

“…Introduction The complex economic relations in the current era increasingly demand the provision of efficient, rational, and comprehensive legal norms. …”
Get full text

Use of ICT to Confront COVID-19 by Yousry Saber El Gamal

“…Supporting a digitized world and staying current in the latest technology will be essential for any country to remain competitive in a post COVID-19 world. …”
Get full text

A quantitative assessment of the behavior of metallic elements in urban soils exposed to industrial dusts near Dunkerque (northern France) by M. Casetta, S. Philippe, L. Courcot, D. Dumoulin, G. Billon, F. Baudin, F. Henry, M. Hermoso, J. Caillaud

“…In this context, the monitoring of industrial PTEs in these urban soils is highly recommended, considering (1) the presence of allotment gardens in the vicinity of emitters and (2) the potential evolution of soil conditions due to increasing flood events.…”
Get full text

Safety, Feasibility, and Tolerability of Ten Days of At-Home, Remotely Supervised tDCS During Gamified Attention Training in Children with Acquired Brain Injury: An Open-Label, Dos... by Athena Stein, Justin Riddle, Kevin A. Caulfield, Paul E. Dux, Maximilian A. Friehs, Philipp A. Schroeder, Michael P. Craven, Madeleine J. Groom, Kartik K. Iyer, Karen M. Barlow

“…When delivered daily, transcranial direct current stimulation (tDCS) may improve attention; however, access to daily in-clinic tDCS treatment can be limited by other commitments, including concurrent therapy, school commitments, and caregiver schedules. …”
Get full text

Climate variability off Africa's southern Cape over the past 260 000 years by K. Purcell, K. Purcell, K. Purcell, M. H. Simon, M. H. Simon, M. H. Simon, E. J. Pryor, E. J. Pryor, S. J. Armitage, S. J. Armitage, H. J. L. van der Lubbe, E. Jansen, E. Jansen, E. Jansen

“…Finally, the data from core MD20-3592 can provide a climatic context for archaeological evidence in South Africa during the MSA.…”
Get full text

Trends and Prospects in Educational Modernisation: A Hermeneutic Approach by A. F. Zakirova, Ye. N. Volodina

“…To overcome this situation and to break this deadlock, a profound reconsideration of the values underlying mechanisms of reform is required, taking into account multifaceted personal, social, national and universal relations, as well as unity of content, forms and means of education.The aims of the research were identified as follows: to analyse the current trends of modernisation in comprehensive schools and higher educational establishments; to justify humanistic mechanisms for improving the modernisation in the context of language education, which performs personally developing and socialising functions under ideological pluralism and opposition of value systems.Methodology and research methods. …”
Get full text

Sala de aula invertida com Tecnologias Digitais e Ferramenta Metacognitiva para potencializar as aulas do Ensino Superior / Flipped classroom with digital technologies and metacogn... by Caroline Medeiros Martins de Almeida, Camila Maria Bandeira Scheunemann, Paulo Tadeu Campos Lopes

“…A utilização do material autossuficiente baseado nas tecnologias digitais auxiliou os alunos na apreensão dos conceitos de fibromialgia, pois oferecia o conteúdo de modo organizado, atendendo as necessidades dos estudantes. /// In the current digital context, students are increasingly involved by digital technologies in their daily lives, which drives their insertion in the educational field, at different levels of education, in order to make classes more attractive, interesting and dynamic. …”

Optimizing a Novel Smartphone App to Prevent Postpartum Depression Adapted From an Evidence-Based Cognitive Behavioral Therapy Program: Qualitative Study by Adam K Lewkowitz, Melissa Guillen, Katrina Ursino, Rackeem Baker, Liana Lum, Cynthia L Battle, Crystal Ware, Nina K Ayala, Melissa Clark, Megan L Ranney, Emily S Miller, Kate M Guthrie

“…Individuals with prior or current depression were excluded. Interviews were recorded, transcribed, and analyzed using deductive and inductive codes to characterize opinions about MBapp and perceptions of challenges and facilitators of use of MBapp or other perinatal or mental health apps. …”
Get full text

Leishmaniases in Ethiopia: a scoping review by Ermias Diro, Fiona Wallace, Mezgebu Silamsaw Asres, Richard Wamai, Hugh Shirley, Grace Grifferty, Eleni Ayele, Katherine O’Brien, Adriana Totten, Philip Coombs, Adrienne M Orriols, Shreyas Mosurkal, Ellie Krulwich, Leah Oruko, Isabel C Roman, Prapti Shah, Riley Fanning-Hughes, Abigail L Williams, Morgan G Wong, Sophia Roe, Khushi Gandhi, Laith Matari, Sara Shaikh, Abigail Binkley, Benjamin J D Boutselis, Amer Chaudhry, Mahlet Haile

“…The identified studies were analysed using an extensive codebook, which was previously developed by this team and adapted to the Ethiopian context to classify the research into different categories.Results A total of 8698 articles were identified. …”
Get full text

Two decades of insecticide resistance in Benin: a retrospective analysis of evolution and drivers by Steve Zinsou Hougbe, Razaki A. Ossé, Roseric Azondékon, Casimir Kpanou, Minassou Juvénal Ahouandjinou, Zul-kifl Affolabi, Koffi Djigbodi Koumodji, Hermann Sagbohan, Esdras Mahoutin Odjo, Constantin Adoha, Boulais Yovogan, Serge Akpodji, Linda Towakinou, Bruno Akinro, Albert Salako, Filémon Tokponnon, Germain Gil Padonou, Lamine Baba-Moussa, Martin Akogbeto

“…The present paper provides a retrospective analysis of these data to assess the current state of insecticide resistance and its evolution over two decades. …”
Get full text

Molecular genetics is on the guard of the law by L. I. Kucherenko, I. V. Pavliuk, O. V. Khromylova

“…In the world, forensic DNA analysis is recognized as one of the most promising areas of development of forensic examinations, and its results are currently one of the most reliable pieces of evidence. …”
Get full text

Life on the Edge: Challenges to Beginning Successful Aging by Fattaneh Hajilou, Tavakkol Aghayari Hir, Ali Pilvari

“…IntroductionIn today's world, the elderly population is rapidly increasing in many countries; yet social policies for both urban and rural communities often overlook this critical issue. …”
Get full text

ECONOMIC AND LEGAL POLICY IN THE FIELD OF SECURITY ON THE MARKET OF NON-BANKING FINANCIAL SERVICES IN UKRAINE by Hanna Buha, Serhii Hermanov, Volodymyr Ihnatenko

“…These principles determine the purpose, objectives, rules, order and procedures of the activities of authorized entities in the context of regulating and developing relations in NFS. …”
Get full text

ROLE OF CYTOXIC T-LYMPHOCYTES IN THE PATHOGENESIS OF PRETERM BIRTH by N. R. Radzhabova, N. Yu. Sotnikova, A. V. Kudryashova, N. Yu. Borzova, A. I. Malyshkina

“…Currently, the existence of a wide range of subpopulations of CD8+T-lymphocytes has been revealed, among which there are subpopulations of naive and effector cells, as well as memory cells. …”
Get full text

Do we need urine drug screens in opioid addiction treatment: An observational study on self-report versus urine drug screens by Alannah McEvoy, Myanca Rodrigues, Brittany B Dennis, Jacqueline Hudson, David C. Marsh, Andrew Worster, Lehana Thabane, Zainab Samaan

“…It is therefore important to consider the context of the patient, and the type of the co-substance used to select patient-centred testing as indicated. …”
Get full text

Advancing life cycle assessment of bioenergy crops with global land use models by Anders Arvesen, Florian Humpenöder, Tomás Navarrete Gutierrez, Thomas Gibon, Paul Baustert, Jan Philipp Dietrich, Konstantin Stadler, Cristina-Maria Iordan, Gunnar Luderer, Alexander Popp, Francesco Cherubini

“…We find that land use-related CO _2 emission for bioenergy range from 2 to 35 tonne TJ ^−1 , depending on bioenergy demand, policy context, year and accounting method. GHG emissions per unit of bioenergy do not increase with bioenergy demand in presence of an emission tax. …”
Get full text

The Symbiotic Bacterial Profile of Laboratory-Reared and Field-Caught <i>Aedes albopictus</i> Mosquitoes from Greece by Elias Asimakis, Ioannis Galiatsatos, Georgia Apostolopoulou, Eleni C. Savvidou, Georgios Balatsos, Vasileios Karras, Vasiliki Evangelou, Eva Dionyssopoulou, Antonios Augustinos, Nikos T. Papadopoulos, Antonios Michaelakis, Panagiota Stathopoulou, George Tsiamis

“…The use of symbiotic bacteria to improve the application of SIT or design combined SIT/incompatible insect technique (IIT) approaches is currently considered. In this context, exploring the microbiota of local mosquito populations is crucial for identifying interesting components. …”
Get full text