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2441
Students of Social Work in the Slipstream of the Politics of Activation: Results of Explorative Studies.
Published 2013-12-01“…Social activation" concentrates and has a focus on a structure of negative sanctions, controlling clients and axiomatic aims - especially in relation to integrating people into the workforce. In this context, non-conditional support is increasingly discredited. …”
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2442
OPTIMIZATION OF IMID-BASED THERAPIES
Published 2024-12-01“…In this case, it is clear that multiple myeloma treatment optimization cannot be achieved by considering multiple myeloma treatment only as applying the appropriate drug combination.In order to ensure the optimization of IMID-based therapies, it is necessary to take a broad perspective.This perspective should include the correct selection of the patient to be treated with IMID, the development and implementation of IMID forms that will increase patient compliance, the use of techniques to predict the development of resistance, side effect management during treatment, preventing the increase in disease burden with appropriate maneuvers by following the disease burden after treatment, and drug-free follow-up.It is recommended to avoid thalidomide in the presence of peripheral neuropathy, to prefer other agents instead of lenalidomide in the presence of renal function loss, and to avoid pomalidomide in patients with COPD.Nex-20, a once-monthly subcutaneous formulation of lenalidomide, is expected to be an important breakthrough in improving patient compliance.Prediction of which patients will develop resistance will be very useful in order to have the best treatment outcomes.Calculation of miRNA risk scores, measurement of lenalidomide metabolite levels in urine, measurement of cereblon levels in blood, or immunohistochemical detection of cereblon levels are some of the methods currently being tried to predict disease resistance.Patients who develop anemia should be treated with erythropoietin, skin reactions should be treated with steroids and antihistamines, diarrhea should be treated with loperamide and colestyramine, and in general, the drug should be discontinued and the same dose or a lower dose should be insisted upon.An important part of treatment is maintenance therapy with lenalidomide. …”
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2443
The Association Between Traumatic Brain Injury and the Risk of Cognitive Decline: An Umbrella Systematic Review and Meta-Analysis
Published 2024-11-01“…Background: There is currently increasing interest in the implication of traumatic brain injury (TBI) as a potential risk factor for long-term neurodegenerative conditions, such as dementia and Alzheimer’s disease (AD). …”
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2444
Exploiting <i>Wolbachia</i> as a Tool for Mosquito-Borne Disease Control: Pursuing Efficacy, Safety, and Sustainability
Published 2025-03-01“…Successes, challenges, and future perspectives are discussed in the context of the current spread of several arboviral diseases, the rise of insecticide resistance in mosquito populations, and the impact of climate change. …”
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2445
Anisotropic flexible stress sensors based on Loofah/CN/MWCNTs
Published 2025-01-01“…Consequently, the loofah skeleton and conductive coating were compressed and released simultaneously, effectively functioning as a variable resistor. As applied stress increased, the loofah framework became more compact, gradually increasing the contact area between carbon-based materials of different sizes, thereby generating new current pathways. …”
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2446
Optimizing influenza vaccine allocation by age using cost-effectiveness analysis: A comparison of 6720 vaccination program scenarios in children and adults in Belgium
Published 2025-06-01“…Results: Of all the vaccination options considered, over 90 % dominated the current Belgian vaccination strategy in terms of cost-effectiveness. …”
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2447
Next generation High-Mobility 2D chalcogenides TFT for display backplane
Published 2025-01-01“…In this context, 2D chalcogenides have emerged as promising candidates for thin-film transistors (TFTs) in display backplanes, offering advantages such as high mobility, low leakage current, mechanical robustness, and transparency. …”
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2448
Review on Autoimmune Reactions in Female Infertility: Antibodies to Follicle Stimulating Hormone
Published 2012-01-01“…This paper summarizes a current clinical classification of female infertility in the context of general activation of autoimmunity and antiovarian autoimmunity by describing serum anti-FSH. …”
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2449
CREATING PUBLIC OPINION AND DEVELOPING SPATIAL CITIZENSHIP THROUGH MAPS: THE CASE OF ZARAGOZA, SPAIN
Published 2017-01-01“… The current context of social transformation and urban changes increases the need for updated knowledge of living spaces. …”
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2450
Medical triage as an AI ethics benchmark
Published 2025-08-01“…Adversarial prompts significantly decreased accuracy. By demonstrating the influence of context and ethical framing on the performance of LLMs, we provide critical insights into the current capabilities and limitations of AI in high-stakes ethical decision making in medicine.…”
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2451
La política de ordenación y desarrollo del País Vasco norte
Published 2020-08-01“…The current context is characterized at the same time by the exacerbation of the territorial tensions with the metropolization of regional capitals, the rise of the periurban phenomenum and the depopulation of rural areas where public services and employments are decreasing, and by the exhaustion of a model of development based on the clustering of productive activity, exploitation of natural resources and the growth of social inequalities. …”
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2452
ANALYSIS OF THE DYNAMICS AND TRENDS IN THE DEVELOPMENT OF MODERN INTERNATIONAL TOURIST MARKET
Published 2021-02-01“…Based on the statistical data of international organizations, the author studied indicators of international tourist flows, identified the main trends in the development of international tourism at the current stage, assessed the impact on the tourism sector of the COVID-19 pandemic and determined possibilities for its development in the context of the economic crisis, showed prospects for the development of the industry.…”
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2453
Rational design of 19F NMR labelling sites to probe protein structure and interactions
Published 2025-05-01“…Here, we exploit the sensitivity of 19F chemical shifts to ring currents by designing labels with direct contact to a native or engineered aromatic ring. …”
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2454
Tumor glyco-immunology, glyco-immune checkpoints and immunotherapy
Published 2025-06-01“…Moreover, they can mediate immune-suppressive effects. For example, increased sialylation can enhance interactions with immune-inhibitory Siglec receptors, and galectin-mediated interactions can modulate immune responses in the context of cancer. …”
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2455
Collaborationists and Forms of Cooperation with the Occupation Authority in Odesa (1941-1944)
Published 2024-12-01“…The topic’s relevance increased considerably after the start of the Russian-Ukrainian war, the occupation of Crimea and part of Donbas transforming collaborationism from a historical notion into a current practical and legal concern. …”
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2456
Pentacene-Based Thin Film Transistor with Inkjet-Printed Nanocomposite High-K Dielectrics
Published 2012-01-01“…Finally, we realized top contact pentacene-TFTs and successfully accomplished the purpose of directly patternability and increase the performance of the device based on the nanocomposite by inkjet printing. …”
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2457
Real-time accident detection in smart cities through IoT devices: A case study
Published 2025-03-01“…The use of sensors on vehicles allows us to detect and manage the current state of the road accident. In this context, an accident detection and reporting system using IoT technologies and a general ontology modeling the accident context are proposed. …”
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2458
Neurorights and Neural Data Towards Legal Protection
Published 2025-07-01“…Technologies such as brain-computer interfaces, electroencephalograms, and brain stimulation are expanding beyond the clinical context, finding application in work, education, entertainment, and the military. …”
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2459
Framework for Institutional Shift of Service Infrastructure in Digital Economy
Published 2025-03-01“…Digital services, platforms, ecosystems, and social networks integrate into the service infrastructure to form a new institutional environment. The current system of formal and informal rules fails to meet this challenge. …”
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2460
All the Faces of Agency in Video Games
Published 2023-11-01“…Apart from the fact that video games are still a current and wide area of study, the reason for academic interest and the publishing of books in this area is also methodological – video game studies use multidisciplinary interactions between various areas of theory and games while demonstrating how video games fit and influence the existing theoretical and methodological models in the humanities.It is in this context that we have an interesting example: Bettina Bódi’s Videogames and Agency (Routledge, 2023). …”
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