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  1. 3261

    From attention to action: Advancing inclusivity in the landscape of anatomy education by Lily Evans, Katie Snow, Aiden Jayanth, Siobhan M. Moyes

    Published 2025-03-01
    “…Application of these methods yielded richer and more nuanced data, thus increasing the validity of the study. Although anatomy education may not currently represent diverse populations, positive action towards change is underway, with many in the discipline eager to actively confront exclusion. …”
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  2. 3262

    Absence of progression risk of chronic kidney disease in patients with urine protein-creatinine ratio below 500 mg/g: a cohort study with competing risk analysis by Jiang Bai, Lijuan Zhang, Jingkai Di, Wenyu Wang, Yawen Wu, Yun Zhou, Yun Zhou, Yun Zhou

    Published 2025-03-01
    “…However, Limited data exist regarding the association between Urine Protein-Creatinine Ratio (UPCR) < 500 mg/g and Chronic Kidney Disease (CKD) progression, particularly in the context of competitive risk analysis. We aimed to investigate the correlation between UPCR and the progression of CKD in patients with UPCR below 500 mg/g.MethodsInitially, 512 patients diagnosed with stages G2-G5 of CKD and UPCR levels below 1,000 mg/g were recruited from the CKD-ROUTE cohort. …”
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  3. 3263

    Validation of the Mild Behavioral Impairment Scale (MBI-S) for brief self-assessment of Mild Behavioral Impairment in people without dementia by Paula Hinkl, Elmar Graessel, Nicolas Rohleder, Peter Landendoerfer, Thomas Kuehlein, Natascha Lauer, Anna Pendergrass

    Published 2025-05-01
    “…Abstract Background Mild Cognitive Impairment (MCI) and Mild Behavioral Impairment (MBI) are important constructs in the context of cognitive decline. MBI can be assessed with the Mild Behavioral Impairment Checklist (MBI-C). …”
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  4. 3264

    Knowledge of Preconception Healthcare and Associated Factors: A Study among Mothers in Jinka Town, Southern Region, Ethiopia by Kassahun Fikadu Tesema, Tamirat Cheneka, Alemayehu Alemu, Mekonen Feyissa, Birhanu Birkaye, Hafiza Mohammed, Eleni Kidu, Getahun Wegaso, Biresaw Wasihun

    Published 2021-01-01
    “…Preconception healthcare is promising to improve the reproductive health status of women and couples if they receive care three months to two years before conception. In the current context of Ethiopia, however, preconception healthcare is overlooked in the continuum of care. …”
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  5. 3265

    Towards a sustainable rare disease and orphan drug ecosystem in Saudi Arabia: policy insights from a multi-stakeholder workshop by Ghada Mohammed Abozaid, Ghada Mohammed Abozaid, Hussain Abdulrahman Al-Omar, Abdulaziz Alrabiah, Asma AlMuaither, Amy Jayne McKnight

    Published 2025-05-01
    “…Through a series of presentations, educational sessions, and plenary discussions, participants examined the current landscape of RDs in SA, identified barriers to accessing ODs, and recommended strategies and initiatives to improve the accessibility, innovation, and sustainability of ODs.ResultsThe workshop highlighted key challenges recognized by a diverse group of 59 participants, including the absence of a national strategy, absent of local RDs and ODs definitions in the Saudi context, limited awareness and understanding of RDs among healthcare professionals, delayed diagnoses, scarcity of treatment and diagnosis centers for RDs, insufficient screening and prevention programs, regulatory hurdles in approving and importing ODs, and financial constraints. …”
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  6. 3266

    Trends in Research on Hypertrophic Cardiomyopathy and Mitochondria From 2003 to 2023: A Bibliometric Analysis by Lulu Yang, Heng Zhang, Zhiyang Zhu, Jianming Wang, Xiaojuan Liu, Lijie Lu, Jinliang Huang, Miaoran Wang, Zhengchuan Zhu

    Published 2025-03-01
    “…The investigation of mitochondria, particularly in the context of cardiovascular medicine and HCM, demonstrates an unstoppable momentum. …”
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  7. 3267

    PROTOCOL: The Application of Information and Communication Technologies in Physical Activity Interventions for Breast Cancer: A Scoping Review Protocol by Xin Chen, Maaz Imam, Yutong Yi, JJ Pionke, Lixcy Vega, Anna Arthur, Jessie Chin, Chungyi Chiu

    Published 2025-06-01
    “…The focus of the scoping review is guided by the mnemonic PCC (Population, Concept, Context) recommended by the JBI Manual for Evidence Synthesis. …”
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  8. 3268

    Clinical applications and research progress of remifentanil by Xu Liu, Zhipeng Meng, Fei Tong

    Published 2025-08-01
    “…This review synthesizes current evidence on its clinical applications, pharmacological advantages, and emerging challenges, including Opioid-Induced Hyperalgesia (OIH) and labor analgesia.MethodsThis study is a systematic evidence review. …”
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  9. 3269

    Feasibility of cognitive testing and ecological momentary assessments using smartphones in middle aged and older adults with insomnia by Sara Ghadimi, Jason Ereso, Alexander J. Kaula, Nick Taptiklis, Francesca Cormack, Cathy Alessi, Jennifer L. Martin, Joseph M. Dzierzewski, Arash Naeim, Sarah Kremen, Tue Te, Constance H. Fung

    Published 2025-07-01
    “…We assessed the feasibility of self-administered cognitive testing via smartphone apps for collecting in-moment, in-context data about a person’s current state (ecological momentary assessment, EMA). …”
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  10. 3270

    Reducing Plasmodium falciparum malaria transmission in Africa: a model-based evaluation of intervention strategies. by Jamie T Griffin, T Deirdre Hollingsworth, Lucy C Okell, Thomas S Churcher, Michael White, Wes Hinsley, Teun Bousema, Chris J Drakeley, Neil M Ferguson, María-Gloria Basáñez, Azra C Ghani

    Published 2010-08-01
    “…However, it remains unclear what overall reduction in transmission is achievable using currently available tools.<h4>Methods and findings</h4>We developed an individual-based simulation model for Plasmodium falciparum transmission in an African context incorporating the three major vector species (Anopheles gambiae s.s., An. arabiensis, and An. funestus) with parameters obtained by fitting to parasite prevalence data from 34 transmission settings across Africa. …”
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  11. 3271

    CO2 methanation over low-loaded Ni-M, Ru-M (M = Co, Mn) catalysts supported on CeO2 and SiC by Chopendra G. Wasnik, Maki Nakamura, Taiki Shimada, Hiroshi Machida, Koyo Norinaga

    Published 2025-03-01
    “…An efficient circulation and utilization of CO2 is critical in the current environmental context. Methanation, an exothermic process, emerges as a critical strategy for effective CO2 utilization. …”
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  12. 3272

    MECHANISMS FOR ENSURING THE ECONOMIC DEVELOPMENT OF RURAL AREAS THROUGH THE FORMATION OF THEIR ENERGY DEPENDENCE BASED ON THE INTENSIFICATION OF BIOFUEL PRODUCTION by Yuliia Okhota, Denys Titov, Svitlana Dotsiuk

    Published 2024-12-01
    “…To achieve this goal, the article discusses the theoretical aspects of energy independence, analyzes current practices of biofuel production, and provides recommendations for their further implementation. …”
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  13. 3273

    Intravesical instillation-based mTOR-STAT3 dual targeting for bladder cancer treatment by Dae Hoon Lee, Jung Ki Yoo, Ki Hwan Um, Wootae Ha, Soo Min Lee, Junseong Park, Min Jeong Kye, Jungyo Suh, Jin Woo Choi

    Published 2024-06-01
    “…Graphical Abstract The current investigation introduces an innovative conceptualization of bispecific short hairpin RNA (bs_shRNA) tailored for the equilibrated modulation of dual genes within a singular cellular context. …”
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  14. 3274

    Propagation Characteristics of Multi-Cluster Hydraulic Fracturing in Shale Reservoirs with Natural Fractures by Lianzhi Yang, Xinyue Wang, Tong Niu

    Published 2025-04-01
    “…Understanding the effects of reservoir and fracturing conditions on fracture propagation is of great significance for optimizing the hydraulic fracturing process and has not been adequately explored in the current literature. In the context of shale reservoirs in Yibin, Sichuan Province, China, the study selects outcrops to prepare samples for uniaxial compression and Brazilian splitting tests. …”
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  15. 3275

    Significant fundamental translational research on breast cancer in China: progress and prospects by LU Yufeng, WANG Han, XIE Yifan, JIANG Yizhou, SHAO Zhimin

    Published 2025-02-01
    “…Breast cancer is the most prevalent malignant tumor that poses a threat to women's health in China, with incidence and mortality rates persistently increasing. Given this critical situation, there is an urgent need to optimize therapeutic options through basic translational research to address current treatment challenges. …”
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  16. 3276

    Landslide activation during deglaciation in a fjord-dominated landscape: observations from southern Alaska (1984–2022) by J. Walden, J. Walden, M. Jacquemart, M. Jacquemart, B. Higman, R. Hugonnet, R. Hugonnet, R. Hugonnet, A. Manconi, A. Manconi, D. Farinotti, D. Farinotti

    Published 2025-06-01
    “…Additionally, many glaciers in this area are retreating out of glacially carved fjords, leaving landslides in contact with deep waterbodies that can substantially increase the reach of a catastrophic failure through displacement waves or hazard cascades. …”
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  17. 3277

    高敏感特質中高齡學習者面對數位學習壓力及疫情焦慮之學習滿意度與後疫情調適:復原力之中介效果 Learning Satisfaction and Post-Pandemic Adaptation in Highly Sensitive Middle-aged and Elderly Learners in the Face of Digital Learni... by 王雅鈴 Ya-Ling Wang, 張伶瑜 Lin-Yu Chang, 羅淇文 Chi-Wen Luo, 林郁文 Yu-Wen Lin

    Published 2025-03-01
    “…This study aims to investigate the relationship between digital learning stress, pandemic anxiety, depression, learning satisfaction and post-pandemic experiences in highly sensitive middle-aged and elderly learners in the context of the widespread adoption of digital learning due to the pandemic, and explore the role of resilience as a mediating variable. …”
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  18. 3278

    “If that would have lessened my symptoms, that would have been great...”: a qualitative study about the acceptability of tecovirimat as treatment for mpox by Sara Paparini, Rosalie Hayes, Benjamin Weil, Will Nutland, Ismael Maatouk, Teodora Wi, Chloe M. Orkin, Rosamund Lewis

    Published 2025-01-01
    “…Conclusions This exploratory study suggest that offering tecovirimat (or comparable emergency-licensed treatments) to people with mpox is acceptable, although uptake will depend on knowledge of mpox treatment options, trust in medicine and medical professionals and provision of relevant information and choice. To increase acceptability of such treatments, clinicians should ensure patients are aware of mpox symptom management options, including pain relief; acknowledge and address patient concerns upfront and within the context of non-stigmatising care; and communicate offers in a consistent and supportive manner in line with locally approved eligibility criteria and protocols at the time.…”
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  19. 3279

    Porous Poly(vinylidene fluoride-co-hexafluoropropylene)/copper oxide nanocomposite membranes for piezoelectric strain sensing by Maryam Al-Ejji, Tamanna Promi, Farah Sangor, Zinab Al-Awa, Sumalatha Bonthula, V. Radhika, Deepalekshmi Ponnamma

    Published 2025-05-01
    “…Moreover, the surface water contact angles of the membranes have slightly increased after loading the nanomaterial into the PVDF-HFP matrix, which strongly influenced the surface energies, indicating hydrophobicity. …”
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  20. 3280

    Research on an Ice-Breaking Mechanism Using Subglacial Resonance by Zegang Tian, Zixu Zhu, Bo Tong, Nianming Hu, Mingyong Hu, Yongbao Liu

    Published 2025-06-01
    “…This method eliminates the need for direct contact between the submarine and the ice layer, solving the current issues with submarine ice-breaking methods that demand high strength from the submarine and pose risks to both the submarine and its crew. …”
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    Article