Helminth Coinfections Modulate Disease Dynamics and Vaccination Success in the Era of Emerging Infectious Diseases by Brice Armel Nembot Fogang, Linda Batsa Debrah, Michael Owusu, George Agyei, Julia Meyer, Jonathan Mawutor Gmanyami, Manuel Ritter, Kathrin Arndts, Derrick Adu Mensah, Tomabu Adjobimey, Achim Hörauf, Alexander Yaw Debrah

“…Helminth infection can also negatively impact vaccine efficacy by suppressing B cell activity, reducing antibody levels, and decreasing vaccine effectiveness against infectious diseases. …”
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Role of NLRP3 Inflammasome in Heart Failure Patients Undergoing Cardiac Surgery as a Potential Determinant of Postoperative Atrial Fibrillation and Remodeling: Is SGLT2 Cotransport... by Rodrigo L. Castillo, Jorge Farías, Cristian Sandoval, Alejandro González-Candia, Esteban Figueroa, Mauricio Quezada, Gonzalo Cruz, Paola Llanos, Gonzalo Jorquera, Sawa Kostin, Rodrigo Carrasco

“…In heart failure (HF) patients undergoing cardiac surgery, an increased activity of mechanisms related to cardiac remodeling may determine a higher risk of postoperative atrial fibrillation (POAF). …”
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Polycystic Ovary Syndrome and the Potential for Nanomaterial-Based Drug Delivery in Therapy of This Disease by Mingqin Shi, Xinyao Li, Liwei Xing, Zhenmin Li, Sitong Zhou, Zihui Wang, Xuelian Zou, Yuqing She, Rong Zhao, Dongdong Qin

“…Polycystic ovary syndrome (PCOS) is the predominant endocrine disorder among women of reproductive age and represents the leading cause of anovulatory infertility, which imposes a considerable health and economic burden. Currently, medications used to treat PCOS can lead to certain adverse reactions, such as affecting fertility and increasing the risk of venous thrombosis. …”
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Hydroxyapatite-filled osteoinductive and piezoelectric nanofibers for bone tissue engineering by Frederico Barbosa, Fábio F. F. Garrudo, Paola S. Alberte, Leonor Resina, Marta S. Carvalho, Akhil Jain, Ana C. Marques, Francesc Estrany, Frankie J. Rawson, Carlos Aléman, Frederico Castelo Ferreira, João C. Silva

“…The biological cues provided by the HAp nanoparticles enhanced the osteogenic differentiation of seeded human mesenchymal stem/stromal cells (MSCs) as observed by the increased ALP activity, cell-secreted calcium deposition and osteogenic gene expression levels observed for the HAp-containing fibers. …”
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Enhanced Broad-Spectrum Efficacy of an L2-Based mRNA Vaccine Targeting HPV Types 6, 11, 16, 18, with Cross-Protection Against Multiple Additional High-Risk Types by Kosuke Tsukamoto, Akio Yamashita, Masatoshi Maeki, Manabu Tokeshi, Hirotatsu Imai, Akira Fukao, Toshinobu Fujiwara, Koji Okudera, Nobuhisa Mizuki, Kenji Okuda, Masaru Shimada

“…Results: We identified that a construct containing E01 (a 5′-untranslated region) and SL2.7 (a poly(A) polymerase recruitment sequence) significantly increased protein expression. …”
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Formulation of best-fit hydrophile/lipophile balance-dielectric permittivity demulsifiers for treatment of crude oil emulsions by C.M. Ojinnaka, J.A. Ajienka, O.J. Abayeh, L.C. Osuji, R.U. Duru

“…The presence of water in crude oil causes corrosion, lowers capacity utilization of production and processing plant parts and pipelines, reduces oil recovery and increases the oil content of the effluent water. The stabilizing factors of crude oil emulsions vary from one oil field to the other and with time in the same well as co-produced water increases, or after a well treatment and Enhanced Oil Recovery Operations (EOR). …”
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Advances in Encapsulating Marine Bioactive Compounds Using Nanostructured Lipid Carriers (NLCs) and Solid Lipid Nanoparticles (SLNs) for Health Applications by Rita Favas, Hugo Almeida, Andreia F. Peixoto, Domingos Ferreira, Ana C. Silva

“…As life expectancy rises and modern lifestyles improve, there is an increasing focus on health, disease prevention, and enhancing physical appearance. …”
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Treatment Methods Dry Form of Age Macular Degeneration — History and Prospects. Review by A. N. Kulikov, M. V. Zakharov, A. A. Volozhev

“…The main treatment for wet AMD is the injection of medications called anti-VEGF agents. Currently, treatment of dry age-related macular degeneration includes modification of risk factors (stop smoking, healthy life style and etc) and dietary supplements containing a combination of certain ingredients (vitamin C, vitamin E, zinc, copper, and lutein with zeaxanthin or beta-carotene) may be able to slow the progression of the disease. …”
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A virus becomes a global concern: research activities on West-Nile virus by Doris Klingelhöfer, Markus Braun, Isabelle M. Kramer, Friederike Reuss, Ruth Müller, David A. Groneberg, Dörthe Brüggmann

“…Currently, West-Nile virus (WNV) is spreading worldwide to colder regions due to climate change. …”
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One-sample missing DNA-methylation value imputation by Christelle Kemda Ngueda, Julia Palm, Flavia Remo, André Scherag, Lutz Leistritz

“…Abstract Background Currently, the most popular methods for missing DNA-methylation value imputation rely on exploiting methylation patterns across multiple samples from the same population. …”
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Entropy-Based Uncertainty in Onshore and Offshore Wind Power: Implications for Economic Reliability by Fernando M. Camilo, Paulo J. Santos, Armando J. Pires

“…In Portugal, wind energy already accounts for approximately 30% of the total installed capacity, with projections reaching 38% by 2030, making it the country’s second largest energy source. In the context of the 2050 carbon neutrality targets, quantifying and managing wind power uncertainty has become increasingly important. …”
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Dissertation council in the state scientific certification system: Organizational and management mechanisms of digital transformation by Sergey I. Pakhomov, Elena A. Loginova, Oleg V. Kulyamin, Mikhail P. Petrov

“…Currently, there is a need to refine the underlying mechanisms of dissertation councils as key elements of the state scientific certification system in Russia. …”
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Combined and progestagen-only hormonal contraceptives and breast cancer risk: A UK nested case-control study and meta-analysis. by Danielle Fitzpatrick, Kirstin Pirie, Gillian Reeves, Jane Green, Valerie Beral

“…<h4>Background</h4>Current or recent use of combined oral contraceptives (containing oestrogen+progestagen) has been associated with a small increase in breast cancer risk. …”
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Fastest Prostate Cancer Prediction on Whole-Mount Pathological Slides Using Self-Reform Multilayer Transformer by Linjie Xu, Xiaotian Yu, Haoming Luo, Jili Wang, Wenjie Liang, Jing Zhang, Zunlei Feng, Cheng Lu, Xiuming Zhang

“…Moreover, pixels in each whole-mount slide of PCa are increased by approximately <inline-formula> <tex-math notation="LaTeX">$4\sim 9$ </tex-math></inline-formula> times, therefore containing more information for diagnosis. …”
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iPSC models of mitochondrial diseases by Sonja Heiduschka, Alessandro Prigione

“…Consequently, most mitochondrial diseases are currently untreatable. Human induced pluripotent stem cells (iPSCs) represent a promising approach for developing human model systems and assessing therapeutic avenues in a patient- and tissue-specific context. iPSCs are being increasingly used to investigate mitochondrial diseases, either for dissecting mutation-specific defects within two-dimensional (2D) or three-dimensional (3D) progenies or for unveiling the impact of potential treatment options. …”
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The PHD transcription factor Cti6 is involved in the fungal colonization and aflatoxin B1 biological synthesis of Aspergillus flavus by Zhang Mengjuan, Lin Guanglan, Pan Xiaohua, Song Weitao, Tan Can, Chen Xuan, Yang Yanling, Zhuang Zhenhong

“…Bioinformatics analysis showed Cti6 is conservative in Aspergillus spp., and mCherry mediated subcellular localization showed that most Cti6 accumulated in the nuclei, which reflected that Cti6 performed its important biological function in the nuclei in Aspergillus spp.. The results of the current study elucidate the roles of PHD domain containing proteins in the mechanism of the infection of crops by A. flavus, and provided a novel target for effectively controlling the contamination of Aspergillus spp. to crops.…”
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C18:0 GM3 ganglioside’s efficacy in LPS-induced parkinsonism: neuroprotection, inflammatory inhibition and gliosis mitigation by Tsung-Ta Liu, Cheng-Tsung Liu, I-Hsun Li, Yu-Chieh Chu, Hao-Yuan Hung, Chuang-Hsin Chiu, Ta-Kai Chou, Shiao-Yun Li, Tin-An Wang, Jui-Hu Shih

“…Abstract Background Parkinson’s disease (PD) is an incurable neurological disorder, and current pharmacological therapies primarily address symptoms without halting disease progression. …”
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Hepatoprotective and antioxidant effects of Glycyrrhiza glabra extracts against TCDD-induced hepatocyte damage in Jian carp (Cyprinus carpio var. Jian) by Du Jinliang, Cao Liping, Jia Rui, Liu Yingjuan, Shen Yujin, Yin Guojun

“…Jian).Jian carp were fed with diet containing 3 doses of GGE (0.1, 0.5 and 1.0 g/kg diet) for 60 days before a single intraperitoneal injection of TCDD (0.6 μg/kg), 72 h after TCDD injection, blood and liver samples were taken for biochemical analysis.The results showed that GGE at 1.0 g/kg diet for 60 days prior to TCDD intoxication significantly reduced the elevated activities of ALT, AST, LDH, AKP and increased the reduced levels of total protein (TP), albumin (Alb) in the serum, markedly inhibited the reduction of the activities of superoxide dismutase (SOD), glutathione peroxidase (GPx), catalase (CAT), total antioxidant capacity (T-AOC), and reduced the malondialdehyde (MDA) formation in liver tissue. …”
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Sustainable agriculture through nano-priming: Evaluating the role of biogenic manganese oxide nanoparticles in mitigating wastewater-induced stress in wheat (Triticum aestivum) by Aneeza ISHFAQ, Sabir HUSSAIN, Tanvir SHAHZAD, Muhammed SHAHID, Faisal MAHMOOD, Syed Raza HUSSAIN, Irfan HAIDRI, Imran KHAN, Mahmoud F. SELEIMAN, Muhammad Ahsan ASGHAR, Muhammad Fuad ANSHORI

“…Control included seeds without MnO-NP priming. The wastewater contained contaminants such as heavy metals and organic pollutants. …”
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Anatomy and function of closing muscle complex of the vagina in health and pelvic organ prolapse by G. B. Dikke, A. D. Makatsariya, A. M. Ziganshin, E. A. Shaikhieva, V. O. Bitsadze

“…In modern literature, the pelvic floor muscles are presented by showing their anatomical location and indicating relevant attachment points, but their combined anatomical, topographic and functional significance is described insufficiently, which the current review was aimed at.Aim: to determine the physiological significance and anatomical units of the vagina occlusor muscle complex, topography and functions in health and in pelvic organ prolapse (POP).Materials and Methods. …”
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