PO54 | FATTY INFILTRATION AND POTENTIAL ADIPOGENIC SHIFT OF SKELETAL MUSCLE CELLS: MULTIPARAMETRIC HISTOLOGICAL ANALYSIS OF MYOSTEATOSIS

“… Myosteatosis, defined as an ectopic fat accumulation within skeletal muscle, has gained increasing clinical relevance as it fits within the context of metabolic disorders and aging. …”
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Chickengunya by Mehwash Kashif, Haya Arshad Ali

“…Other symptoms include fatigue  , nausea aphthae , erosions and cheilitis atypical manif neurological, cardiovascular, skin, ocular, renal and other manifestations. 4 Only a blood test can definitively diagnose chikungunya as symptoms are not always easy to tell apart from other conditions. Currently, there is no vaccine or antiviral treatment. …”
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Assessment of synergy-assisted EMG-driven NMSK model for upper limb muscle activation prediction in cross-country sit-skiing double poling by Xue Chen, Zhongxue Yuan, Xianzhi Gao, Yanxin Zhang, Chenglin Liu, Bo Huo, Bo Huo

“…However, frequent shoulder joint movements significantly increase the incidence of shoulder joint disorders. …”
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Mitigating fatigue in long COVID patients with MYPplus: a clinical observation by Yu-Jin Choi, Jin-Seok Lee, Jin-Yong Joung, Seung-Ju Hwang, Young-Yil Kim, Chang-Gue Son

“…It is estimated that approximately 10% of individuals who contact COVID-19 develop Long COVID, with fatigue and brain fog being among the most commonly reported and debilitating symptoms. …”
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Oral-Delivery Lactococcus lactis expressing cherry fusion lactoferrin peptides against infection of avian pathogenic Escherichia coli in chickens by Zhuoran Li, Xueying Wang, Dianzhong Zheng, Fuzhen Han, Yue Li, Han Zhou, Jiaxuan Li, Wen Cui, Yanping Jiang, Xiaona Wang, Weichun Xie, Lijie Tang

“…Historically, antibiotics and vaccinations currently control APEC infections in poultry, however, antibiotic-resistant strains and heterologous serotypes limit their effectiveness. …”
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Smart Packet Delivery in Mobile Underwater Sensors Networks (M-CTSP) by Abdul Khan, Miguel-Angel Luque-Nieto, Ali Akbar Siddique

“…This research is focused on leveraging the Travelling Salesman Problem (TSP) to establish the optimal route of getting from a source node to a destination node in an underwater dynamic location. In this context, all nodes are mobile and slightly adjust their positions due to water currents. …”
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Digital Transformation Strategy of Aerospace Industry by Pu Sun, Weijia Yuan, Fengli Sun, Qian Shi, Shengyou Shi, Guoqing Wang

“…The aerospace industry, as an important representative of high-end manufacturing, plays an irreplaceable role in the development of new-quality productivity. In the context of increasingly complex projects and rapid iteration of new technologies, the development model of the aerospace industry is facing significant challenges and urgently requires digital transformation to promote high-quality development of the industry. …”
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Supply Chain Model for Mini Wind Power Systems in Urban Areas by Isvia Zazueta, Edgar Valenzuela, Alejandro Lambert, José R. Ayala, Rodny Garcia

“…The pursuit of energy security has become one of the most important challenges facing modern societies worldwide. The increase in energy consumption and the need to promote sustainability puts pressure on power generation systems. …”
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Standardized Outcomes for Randomized Controlled Trials Targeting Early Interventions in Patients With Moderate-to-Severe Traumatic Brain Injury: Protocol for the Development of a C... by Raphael Cinotti, Yvan Derouin, Amandine Chenet, Lydia Oujamaa, Bertrand Glize, Yoann Launey, Claire Dahyot-Fizelier, Emmanuelle Cartron, Melodie Renvoise, Benedicte Sautenet, Veronique Sebille

“…In the last 20 years, there has been an increase in clinical trials in neurocritical care, leading mostly to negative results. …”
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Health and economic evaluation of cytomegalovirus vaccination strategy among young women in China: a modelling study by Bin Zhang, Gang Qin, Jun-Tao Shu, You-Jia Wu, Yin-Hua Jiang, Yi-Wen Ge, Meng-Zhao Yin

“…Background Congenital cytomegalovirus (cCMV) infection imposes a substantial economic burden on both families and society in China. There is currently a paucity of dynamic models to study cytomegalovirus (CMV) vaccination strategies for China’s high-seroprevalence population (over 95%). …”
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Oral vs. Outpatient Parenteral Antimicrobial Treatment for Infective Endocarditis: Study Protocol for the Spanish OraPAT-IE GAMES Trial by Guillermo Cuervo, Marta Hernández-Meneses, Arístides de Alarcón, Rafael Luque-Marquez, María M. Alonso-Socas, Ana López-Lirola, Víctor González-Ramallo, Ane J. Goikoetxea-Agirre, David Nicolás, Miguel A. Goenaga, Esperanza Merino, Francesc Escrihuela-Vidal, Pilar Martín-Dávila, Belén Loeches, Lucía Boix-Palop, Oriol Gasch, Marta Camprecios, Alicia Hernández-Torres, Lara García-Álvarez, Marcos Pajarón, María Angels Ribas, Rosa Blanes-Hernández, Inmaculada López-Montesinos, Luis E. López-Cortés, Bárbara Vidal, Mariana Fernández-Pittol, Dolores Navarro, Asunción Moreno, Coral Sala, Juan Ambrosioni, José M. Miró, OraPAT-IE GAMES Investigators

“…Conclusion In a global context of limited healthcare resources and a sustained increase in elderly and frail patients, it is of great importance to demonstrate the effectiveness and safety of outpatient management strategies that could reduce the duration of conventional hospitalizations with their potential complications and inherent costs. …”
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OPTIMIZATION OF IMID-BASED THERAPIES by Murat Çınarsoy

“…In this case, it is clear that multiple myeloma treatment optimization cannot be achieved by considering multiple myeloma treatment only as applying the appropriate drug combination.In order to ensure the optimization of IMID-based therapies, it is necessary to take a broad perspective.This perspective should include the correct selection of the patient to be treated with IMID, the development and implementation of IMID forms that will increase patient compliance, the use of techniques to predict the development of resistance, side effect management during treatment, preventing the increase in disease burden with appropriate maneuvers by following the disease burden after treatment, and drug-free follow-up.It is recommended to avoid thalidomide in the presence of peripheral neuropathy, to prefer other agents instead of lenalidomide in the presence of renal function loss, and to avoid pomalidomide in patients with COPD.Nex-20, a once-monthly subcutaneous formulation of lenalidomide, is expected to be an important breakthrough in improving patient compliance.Prediction of which patients will develop resistance will be very useful in order to have the best treatment outcomes.Calculation of miRNA risk scores, measurement of lenalidomide metabolite levels in urine, measurement of cereblon levels in blood, or immunohistochemical detection of cereblon levels are some of the methods currently being tried to predict disease resistance.Patients who develop anemia should be treated with erythropoietin, skin reactions should be treated with steroids and antihistamines, diarrhea should be treated with loperamide and colestyramine, and in general, the drug should be discontinued and the same dose or a lower dose should be insisted upon.An important part of treatment is maintenance therapy with lenalidomide. …”
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Justification of military neutrality of the Republic of Serbia at a time of erosion of neutrality in Europe by Kajtez Ilija, Starčević Srđan

“…Increase of NATO members, as well as abandoning neutrality under the influence of globalization and negative experiences of neutral countries in the 20th century, strengthens this assertion. …”
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Evaluation of the Clear Fear Smartphone App for Young People Experiencing Anxiety: Uncontrolled Pre– and Post–Follow-Up Study by Chiara Samele, Norman Urquia, Rachel Edwards, Katie Donnell, Nihara Krause

“…Eligible participants were aged between 16 and 25 years with mild to moderate anxiety but not currently receiving treatment or in contact with specialist mental health services or using other interventions or apps to help monitor or manage their mental health. …”
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Leaving no one behind: the impact of disability and socioeconomic status on maternal continuum of care by Ebisa Turi, Lisa Gold, Ha N.D Le, Hasheem Mannan, Eric H.Y. Lau, Julie Abimanyi-Ochom

“…Higher maternal education (AOR = 1.63–2.27), female-headed household (AOR = 1.14, 95% CI: 1.07–1.22), currently working (AOR = 1.29, 95% CI:1.22–1.37) and wealth quintile (increasing from poor to the richest (AOR = 1.24–2.18) were positively associated with higher odds of completing the CoC. …”
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CircPWWP2A promotes renal interstitial fibrosis through modulating miR-182/ROCK1 axis by Qian Huang, Kaiyi Zhong, Jiali Wei

“…Despite ongoing research, the mechanisms underlying renal fibrosis are still not well understood, and there is currently a lack of effective treatments available. …”
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A review of private forest owner typologies with potential to contribute to social milieu research in forest policy by Peter K. Aurenhammer, Max Krott

“…Furthermore, their broader geographical scope can complement the currently German-centric milieu literature.In conclusion, PFO typology research and social milieu research are mutually beneficial. …”
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Assessing crack formation and strain distribution in concrete structures using externally installed fiber optic sensors by Henrik Becks, Matthias Högemann, Josef Hegger, Martin Classen

“…The structural integrity of many European bridges is increasingly compromised by rising traffic loads and gradual deterioration. …”
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Performance Evaluation and Optimization of 3D Gaussian Splatting in Indoor Scene Generation and Rendering by Xinjian Fang, Yingdan Zhang, Hao Tan, Chao Liu, Xu Yang

“…Firstly, utilizing a self-collected dataset, a comprehensive comparison was conducted among COLLI-SION-MAPping (abbreviated as COLMAP (V3.7), an open-source software based on Structure from Motion and Multi-View Stereo (SFM-MVS)), Context Capture (V10.2) (abbreviated as CC, a software utilizing oblique photography algorithms), Neural Radiance Fields (NeRF), and the currently renowned 3DGS algorithm. …”
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The role of community health workers in addressing the global burden of ear disease and hearing loss: a systematic scoping review of the literature by James O'Donovan, Misha Verkerk, Niall Winters, Shelly Chadha, Mahmood F Bhutta

“…We performed a systematic scoping review to identify evidence on how CHWs are currently deployed in the prevention, screening, diagnosis, treatment and management of ear disease and hearing loss; methods to train and support CHWs in this context; and cost-effectiveness of CHWs.Methods We performed a systematic search of the literature from September 1978 to 18 March 2018 from 11 major databases and the grey literature.Results We identified 38 original studies that met the inclusion criteria, taking place across South Asia (n=13), Oceania (n=7), North America (n=7), South America (n=6) and Africa (n=5). 23 studies showed CHWs can increase community participation in screening. …”
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