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  1. 2421
  2. 2422

    Neutrophil-to-Lymphocyte ratio as surrogate for JAK2V617F suppression and event-free survival in polycythemia vera by Tiziano Barbui, Arianna Ghirardi, Victoria Empson, Francesca Fenili, Giuseppe Gaetano Loscocco, Annalisa Condorelli, Alessandra Iurlo, Daniele Cattaneo, Elena Rossi, Valerio De Stefano, Paola Guglielmelli, Christoph Klade, Heinz Gisslinger, Alessandro Rambaldi, Joseph M. Scandura, Alessandro Maria Vannucchi

    Published 2025-08-01
    “…Abstract Chronic systemic inflammation is a key driver of polycythemia vera (PV) progression, but the immunomodulatory effects of current treatments remain poorly defined. The neutrophil-to-lymphocyte ratio (NLR) is an accessible biomarker of systemic inflammation proven in other contexts, but its role in monitoring PV disease activity has not been established. …”
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  3. 2423

    The clinically applied PARP inhibitor talazoparib ameliorates imiquimod-induced psoriasis in mice without reducing skin inflammation by Petra Molnár, Máté Ágoston Demény, Beáta Várkonyi, Beáta Várkonyi, Zsuzsanna Polgár, Ágnes Pór, Ilona Kovács, Andrea Szegedi, Andrea Szegedi, Attila Gábor Szöllősi, Attila Gábor Szöllősi, Magdolna Szántó

    Published 2025-02-01
    “…BackgroundConsidering the role PARPs play in inflammation, we assessed the effect of PARP inhibition in an inflammatory skin condition, psoriasis, to explore novel avenues for the potential repurposing of PARP inhibitors that are currently used in tumour therapy.MethodsThe imiquimod (IMQ)-induced model of psoriasis was applied in BALB/c mice. …”
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  4. 2424
  5. 2425

    Concurrent Dengue and Malaria infection: A Double Trouble by Syed Bilal Hashmi, Manal Adil, Laraib Malik

    Published 2024-12-01
    “…A study conducted in Karachi on one hundred and fourteen patients with fever of less than or equal to 10 days duration, severe body aches, rash and bleeding manifestations showed that the frequency of dual dengue and malaria infection was 23.21% [8]. Current efforts to contain the spread of infectious diseases such as malaria and dengue are inadequate. …”
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  6. 2426

    Image-based honey bee larval viral and bacterial diagnosis using machine learning by Duan C. Copeland, Brendon M. Mott, Oliver L. Kortenkamp, Robert J. Erickson, Nathan O. Allen, Kirk E. Anderson

    Published 2025-08-01
    “…When tested on an independent dataset from Illinois containing additional viral pathogens not present in training data, the models showed higher accuracy for EFB (72–88%) than viral infections (28–68%), highlighting both the promise and current limitations of this approach. …”
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  7. 2427

    3D-printed resin for permanent/definitive restorations: meta-analysis for bond strength by Minjoo Ki, Marc Hayashi, Mijoo Kim

    Published 2025-05-01
    “…Background Three-dimensional (3D) printing technologies have gained increasing popularity in restorative dentistry for fabricating polymer-based restorations. …”
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  8. 2428

    An explainable AI-driven deep neural network for accurate breast cancer detection from histopathological and ultrasound images by Md. Romzan Alom, Fahmid Al Farid, Muhammad Aminur Rahaman, Anichur Rahman, Tanoy Debnath, Abu Saleh Musa Miah, Sarina Mansor

    Published 2025-05-01
    “…While deep learning has demonstrated potential, many current models struggle with limited accuracy and lack of interpretability. …”
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  9. 2429

    Formal Features Of Image Construction In Ghost Films by Asia Ali Mahmood

    Published 2024-12-01
    “…Due to the popularity and popularity of this type of film, modern cinema has worked to increase the element of suspense by producing ghostly images and sounds that have been processed using innovative artistic methods that contain in their narrative structure extremely complex plots that provoke fear, panic and terror, relying on the technological development that has included the film production sector with all its technical joints at the levels of image and sound, so that these ghostly creatures have artistic metaphors for realistic topics that touch on human life, perceptions and changing culture. …”
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  10. 2430
  11. 2431

    The substance use profiles of adults who sought mental health and addiction services through a centralized intake process in Nova Scotia (2020–2021) by Matiwos Soboka, Philip G. Tibbo, Sherry H. Stewart, Sherry H. Stewart, Sherry H. Stewart, Patryk Simon, JianLi Wang, JianLi Wang

    Published 2024-12-01
    “…BackgroundDespite the increasing substance use in Canada, our understanding of how substance use varies based on the intersections of gender, ethnicity/race, and income sources among preclinical populations remains limited. …”
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  12. 2432

    MOTIVATIONAL COMPONENT AS A SUCCESS TO ORGANIZE AN INDEPENDENT WORK OF STUDENTS AT THE DEPATMENT OF THERAPEUTIC DENTISTRY by Yu. V. Sidash

    Published 2019-03-01
    “…The process of the study isto create a sincere atmosphere of communication in the audience, establish contact with students, achieve mutual understanding and form a sense of confidence in the student. …”
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  13. 2433

    The Effect of Adzuki Bean Extract on Antioxidant and Inflammatory Indices in Diabetic Rats by Ewelina Król, Halina Staniek, Zbigniew Krejpcio, Dawid Szczepankiewicz, Małgorzata Gumienna, Barbara Górna

    Published 2024-02-01
    “…In order to achieve this goal, plant materials that contain compounds with high antioxidant potential, exhibit digestive enzyme inhibiting activity, or contain substances that improve insulin sensitivity are selected. …”
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  14. 2434

    High dynamic range capillary electrophoresis method for sensitive detection of low-frequency driver mutations by Nobue Tamamura, Yoshihiko Hagiwara, Hirokazu Kato, Yusuke Ono, Kenji Takahashi, Kazuya Koyama, Hiroki Sato, Tetsuhiro Okada, Hidemasa Kawabata, Yu Ohtaki, Chiho Maeda, Miyuki Mori, Shin-ichi Chiba, Mishie Tanino, Kenzui Taniue, Takashi Anazawa, Ryoji Inaba, Yusuke Mizukami

    Published 2025-07-01
    “…Abstract Cancer genomics aims to personalize treatments by identifying genetic abnormalities in cancer cells. However, current analytical techniques face limitations in simplicity and cost-effectiveness. …”
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  15. 2435
  16. 2436

    Jembrana disease in Indonesia: An updated review by Dewa Ketut Meles, Aswin Rafif Khairullah, Suzanita Utama, Wurlina Wurlina, Sri Mulyati, Imam Mustofa, Rimayanti Rimayanti, Tita Damayanti Lestari, Ikechukwu Benjamin Moses, Syahputra Wibowo, Bantari Wisynu Kusuma Wardhani, Dea Anita Ariani Kurniasih, Muhammad Khaliim Jati Kusala, Riza Zainuddin Ahmad, Ima Fauziah, Wasito Wasito, Adeyinka Oye Akintunde

    Published 2025-03-01
    “…Clinical symptoms of Jembrana illness in cattle include elevated fever, bloody diarrhea in the stool, increased salivation, and enlarged lymph nodes. Jembrana illness is transmitted through direct contact between sick and healthy cows. …”
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  17. 2437

    Heat Removal Performance Analysis of HTR-PM Reactor Cavity Cooling System under Accident Condition by QIN Haiqi, LI Xiaowei, ZHANG Li, LIU Xiongbin, ZHENG Yanhua, WU Xinxin

    Published 2025-04-01
    “…When the atmosphere temperature increases from 25 ℃ to 42 ℃, the maximum concrete temperature increases from 86 ℃ to 111 ℃. …”
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  18. 2438
  19. 2439

    Quantitative characterization of adsorbed and free shale oil microscopic distribution based on nuclear magnetic resonance: a case study of Chang 7 member of Triassic Yanchang Forma... by Fei LIU, Jinliang DU, Lin SUN, Ruiliang GUO, Bofei HAO, Peng LIU

    Published 2025-05-01
    “…Quartz-related pores significantly increase the specific surface area of pores, thus providing more occurrence sites for adsorbed oil, whereas an increase in clay mineral content significantly reduces the pore volume available for free oil. …”
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  20. 2440

    Efficacy and Safety of Various Intravenous Thrombolytics for Acute Ischemic Stroke (AIS) at Various Dosages: A Systematic Review and Network Meta-Analysis by Yibin Hu, Shengxian Wu, Haixuan Zhang, Kangfeng Wang, Lijuan Zhang, Yizheng Ma, He Li

    Published 2024-12-01
    “…Abstract Background Currently, there is limited evidence on the efficacy and safety of various thrombolytic drugs at different dosages for the treatment of acute ischemic stroke (AIS). …”
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