Therapeutic potential of microRNAs in neurological disorders: mechanisms, biomarkers, and emerging therapeutic strategies by Sourav Pal, Subhajit Mandal

“…We also explore the future of miRNA research in the context of precision medicine, highlighting the importance of targeted delivery, safety optimization, and integration of patient-specific molecular profiles. …”
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Theoretical Research on the Shear Mechanical Properties and Size Effect of Recycled Concrete Beams Without Stirrups by Chunyang Liu, Guangkai Zhou, Hao Wang, Yilin Wang

“…As a new type of building material with great potential, recycled concrete is playing a vital role in the context of the current construction industry’s pursuit of sustainable development. …”
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Overcoming immunosuppression in cancer: how ketogenic diets boost immune checkpoint blockade by Victoria E. Stefan, Daniela D. Weber, Roland Lang, Barbara Kofler

“…., high-fat low-carbohydrate diets, have been shown to have antiproliferative and immunomodulatory effects in various preclinical cancer studies. Here, we review current knowledge of the complex interplay of KDs and the anti-tumor immune response in the context of ICB therapy, to update our understanding of diet-induced immunometabolic reprogramming in cancer. …”
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Horticultural performance and QTL mapping of snap bean (Phaseolus vulgaris L.) populations with organic and conventional breeding histories by Hayley E. P. Richardson, Ryan M. King, Joel Davis, James R. Myers

“…IntroductionImproving crop cultivars for use on organic farms is pertinent, as current elite germplasm is less resilient within the more variable context of organic farm environments. …”
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Data-Driven Proactive Early Warning of Grid Congestion Probability Based on Multiple Time Scales by Haobo Fu, Ruizhuo Wang, Bingxu Zhai, Yuanzhuo Li, Pengyuan Li, Rui Zhang, Haoyuan He, Siyang Liao

“…With the development of new power systems, the increased interactive demand on the load side, and the high proportion of renewable energy sources on the power side, grid congestion problems due to increased system uncertainty are becoming more frequent. …”
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Requests for physician-assisted suicide in German general practice: frequency, content, and motives– a qualitative analysis of GPs’ experiences by Luise Farr, Juliane Poeck, Claudia Bozzaro, Jutta Bleidorn

“…Methods We conducted 19 guideline-based interviews with GPs currently or formerly practicing in Germany (study period: 03/22–12/22). …”
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Histopathological study of the testes in three genetic lines of Japanese quail (Coturnix japonica) exposed to different doses of L-Arginine by Ahmed Shaker, israa Abd Alsada, Questan Ameen, Luay Alsalihi, Adel Hussen

“…Birds were divided by color into three groups and fed diets containing different arginine levels from age 30 to 90 days. …”
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Studying and Characterization of Coating of Zein–CaSiO3 Composite on Polyetheretherketone Implant Material by Sama Abdulrazzaq, Thekra Ismael Hamad

“…Each group was characterized by atomic force microscopy, field emission scanning electron microscope, Fourier-transform infrared spectroscopy, water contact angle, and adhesion strength. The lowest water contact angle was obtained for Group 1: 10% wt and 90% wt were (26.64° and 27.13°, respectively), and increasing amounts of zein in comparison to quantities of CaSiO3 resulted in increased adhesion strength of the composite material to the substrate. …”
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Three-step fabrication of TiO2CdS spheres on SiO2 supports for enhanced hydrogen evolution performance by Zhengyou Li, Alexander V. Soldatov, Aslam Hossain

“…The overpotential exhibited a notable decrease from 793 mV to 264 mV at a current density of 10 mA/cm², demonstrating the improved electrocatalytic efficiency as CdS concentration increased. …”
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Minimizing unnecessary proBNP blood tests: an evaluation of a pop-up form implementation in general practice by Morvarid Sophia Esmaeilzadeh, Anna Elise Engell, Henrik Løvendahl Jørgensen, Bent Struer Lind

“…In this group, the median proBNP level increased from 12.1 pmol/L before the intervention to 13.5 pmol/L after the intervention (p < 0.0001).Conclusions This study demonstrates a significant decrease in the number of proBNP requests from general practitioners in the Capital Region of Denmark after the introduction of a pop-up form in the requisition system containing the current guidelines.…”
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Dopamine modulates persistent synaptic activity and enhances the signal-to-noise ratio in the prefrontal cortex. by Sven Kroener, L Judson Chandler, Paul E M Phillips, Jeremy K Seamans

“…When the background DA was eliminated by depleting DA with reserpine and alpha-methyl-p-tyrosine, or by preparing corticolimbic co-cultures without the VTA slice, Up-states could be enhanced by low concentrations (0.1-1 microM) of DA that had no effect in the VTA containing cultures. Finally, in spite of the concentration-dependent effects on Up-states, exogenous DA at all but the lowest concentrations increased intracellular current-pulse evoked firing in all cultures underlining the complexity of DA's effects in an active network.…”
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In vitro and preclinical evaluation of the antifungal activity of 6-methoxy-1 H-indole-2-carboxylic acid produced by Bacillus toyonensis strain OQ071612 formulated as nanosponge hy... by Sayed E. El-Sayed, Neveen A. Abdelaziz, Ghadir S. El-Housseiny, Khaled M. Aboshanab

“…Abstract Background In a previous study, 6-methoxy-1 H-indole-2-carboxylic acid (MICA) was isolated from the culture broth of Bacillus toyonensis strain OQ071612 soil isolate in our laboratory, and it demonstrated promising antifungal activities. The current study was designed to create a nanosponge (NS)-hydrogel (HG)-containing MICA followed by in vitro and preclinical evaluation for potential clinical use in the topical treatment of mycotic infections. …”
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Malted Multi-millet based Probiotic Dairy Beverage: Nutritional, Sensory, Physicochemical and Microbiological Characterization by G. Swarnalatha, S. Sharath Kumar, T. V. Madhavi

“… In the current study conducted during November, 2023–April, 2024 , malted multimillet flours (MMF) viz., Finger millet, Foxtail millet and Little millet were used for preparation of probiotic lassi. …”
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The Design and Analysis of a Proportional Solenoid with Experimental Validation of Static and Dynamic Behavior by Ercan Düzgün, Gürsel Şefkat

“…The solenoid achieved a constant magnetic force of 45 ± 3 N with a current of 1.3 A over a working range of 1–3 mm. The dynamic model, incorporating data from ANSYS, yielded results that closely matched the experimental findings.…”
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Optimization of the defense forces personnel under mobilization conditions: The role of occupational selection as a personnel allocator by V. V. Kalnysh, A. V. Shvets

“…The second problem is the age aspect in the ranges of 20-30, 30-40 and 40-60 years, for which it is necessary to develop and apply the criteria of occupational suitability for each of the currently relevant professions. A generalized definition of the psychological readiness state was formulated as a stable, multifaceted and hierarchically structured result of preparation for a certain activity, which contains a number of subsystems adequate to the requirements, content and conditions of the activity. …”
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New multifactor spatial prediction method based on Bayesian maximum entropy by YANG Yong, ZHANG Chutian, HE Liyuan

“…., organic matter and heavy metal content) are vital to soil quality evaluation and regional environment assessment. Currently, the spatial distribution of soil properties is usually predicted with classical geostatistics or environmental correlation. …”
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Evolution of the burden of active hepatitis C virus infection in England from September 2015 to September 2016: a repeated cross-sectional analysis by Jason Gordon, Anna Maria Geretti, Lynsey Corless, Laure Lacoin, Michael Hurst, Nathan R Hill, Richard Aspinall, Yuxiang Gao-Du, Liam Mistry, David Mutimer

“…From 2015 to 2016, there was a progressive increase in the proportion of treated patients who were non-cirrhotic, with current IVDU and non-liver transplant recipients.Conclusions The characteristics of patients with HCV remaining in contact with specialised care evolved with a changing landscape of treatment and related health policy. …”
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Dielectric Passivation Treatment of InGaN MESA on Si Substrates for Red Micro-LED Application by Hongyu Qin, Shuhan Zhang, Qian Fan, Xianfeng Ni, Li Tao, Xing Gu

“…Experimental results reveal that Al₂O₃ exhibits superior thermal stability and lower current leakage under high-temperature annealing, while HfO₂ achieves higher light-output power (LOP) and efficiency under increased current densities. …”
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Epidemiological Informing of the Population in Cities: Models and Their Application by Vasiliy Osipov, Marina Osipova, Sergey Kuleshov, Alexandra Zaytseva, Aleksey Aksenov

“… With an increase of population density and contacts between people, the emergence of new biological viruses, the threat of various epidemics is growing. …”
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Illuminating Bilateral Breast Cancer: A Multicenter Experience and Clinical Observations by Berkan Karabuğa, Mustafa Büyükkör, Ekin Konca Karabuğa, Sedat Yıldız, Mirmehdi Mehtiyev, Havva Yeşil Çınkır, Sıla Soylu Koçoğlu, Hacer Demir, Ozan Yazıcı, Doğan Uncu, Ömür Berna Öksüzoğlu, Ülkü Yalçıntaş Arslan

“…In multivariate regression analysis, hormone receptor negativity was identified as an independent risk factor for decreased DFS among all BBC patients. Our study is noteworthy for shedding light on the clinical features of BBC in the context of current knowledge and for its multicenter design.…”
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