Cancer Vulnerabilities Through Targeting the ATR/Chk1 and ATM/Chk2 Axes in the Context of DNA Damage by Anell Fernandez, Maider Artola, Sergio Leon, Nerea Otegui, Aroa Jimeno, Diego Serrano, Alfonso Calvo

“…Several small-molecule inhibitors targeting ATM/Chk2 or ATR/Chk1 are currently being tested in preclinical and/or clinical settings, showing promise in cancer models and patients. …”
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Increasing efficiency and sustainability: A comparative analysis of concrete 3D printing and traditional methods based on case studies by Karamara Merve, Bogdanski Moritz-Ole, Zöller Raphael, Albrecht Sophie Viktoria, Linner Thomas, Bock Thomas, Braml Thomas

“…These are particularly important in the context of the current skilled labour shortage and emphasis on resource efficiency in construction. …”
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Increasing reliability of traction electric motors of diesel locomotives taking into account thermophysical parameters of insulation and armature winding conductors by V. I. Kiselev, T. O. Vakhromeeva, A. I. Fedyanin

“…The winding model is represented separately by a conductor and insulation, between which contact conditions are specified. The conductor of the calculation model heats up to 120 °C from the current flow. …”
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Does neoadjuvant chemotherapy increase the survival in patients with locally advanced gastric cancer patients? – A real-world evidence by Murugesan Janarthinakani, Selvaraj Kalaiselvi, Rajamani Priyadarshini, Seshachalam Arun, K Shashidhar, R Krishnakumar, N Manjunath, Sirigeri Roopa, S G Raman

“…However, these findings were statistically not significant. The current study has contributed an important finding to the existing evidences of clinical practice in an Indian setting. …”
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Subunit-specific mechanisms of isoflurane-induced acute tonic inhibition in dentate gyrus granule neuron by Zhiqiang Yu, Xiaodan Chen, Zheng Liu, Ran Ding, Jin Xu

“…Furthermore, this study demonstrated that the increased tonic current in DGGCs was dependent on the δ subunit-containing GABAARs by using transgenic δ subunit knockout mice. …”
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A Critical Analysis of Cooperative Caching in Ad Hoc Wireless Communication Technologies: Current Challenges and Future Directions by Muhammad Ali Naeem, Rehmat Ullah, Sushank Chudhary, Yahui Meng

“…In this paper, we discuss the problems and issues in the current wireless ad hoc paradigms as well as spotlight versatile cooperative caching as the potential solution to the increasing complications in ad hoc networks. …”
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Pasture resilience towards landscape changes: assessing pastures quality in the context of land-use and land-cover changes in Romania by Ana-Maria CALOTA, Ieanaa PATRU-STUPARIU

“… The current global context (the expansion of urban concentration, the need to produce green energies, the aging of rural population) and often, the volatile legislative framework create opportunities for irreversible landscape and, implicitly environmental changes. …”
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Predicting current and future potential habitat distribution of fig tree (Ficus-Carica) in Morocco using Maxent Modeling by amal labaioui, Rachid Razouk, Lahcen HSSAINI

“…This work was carried out with the objective of delimiting the areas suitable for the fig tree currently and by 2050 to guide the new plantations of the fig tree. …”
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Use of Artificial Intelligence in Adolescents’ Mental Health Care: Systematic Scoping Review of Current Applications and Future Directions by Gauri Sharma, Mark J Yaffe, Pooria Ghadiri, Rushali Gandhi, Laura Pinkham, Genevieve Gore, Samira Abbasgholizadeh-Rahimi

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Unraveling the Complexity of the Ne/Nc Ratio for Conservation of Large and Widespread Pelagic Fish Species: Current Status and Challenges by Chrystelle Delord, Sophie Arnaud‐Haond, Agostino Leone, Jonathan Rolland, Natacha Nikolic

“…Secondly, we outline current knowledge about the influence of life history traits on the Ne/Nc ratio in the light of examples drawn from large and abundant pelagic fish species. …”
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Temporal comparison of land-use changes and biodiversity in differential IUCN protected-area categories of Bangladesh in the context of co-management by Kazi Mohammad Masum, Mohammad Sagar Islam, Md. Sahinur Islam Fahim, Masud Parvej, Mehvish Majeed, Md Mahbub Hasan, Asyraf Mansor

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Strategic Aspects of Human Capital Development in Ukraine in the Context of Integration of Veterans into the Spheres of Industry 4.0 and 5.0 by Babichev Anatolii V., Peliukh Oleksandr I.

“…The article is devoted to the topical problem of integration of veterans into high-tech sectors of the Ukrainian economy, in particular into the spheres of Industry 4.0 and 5.0. In the context of a prolonged cyber war and the expected increase in the number of veterans to 5-6 million people, the issue of their effective reintegration into civilian life is of strategic importance for the country. …”
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Features of etiology, pathogenesis, treatment and prophylaxis of periodontal diseases in pregnant women in the context of iron deficiency anemia (review of the literature) by O. H. Boichuk-Tovsta, O. H. Boichuk

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Frequency Domain Sampling Optimization of Cable Defect Detection and Location Method Based on Exponentially Increased Frequency Reflection Coefficient Spectrum by Kuangyi Jiang, Kai Zhou, Xiang Ren, Yefei Xu

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Evaluation of the federal hospital atlas in the context of the hospital reform 2024: a critical analysis of the healthcare provision in German hospitals by Jonas Roos, Theresa Isabelle Wilhelm, Ron Martin, Kristian Welle, Elio Assaf, Robert Kaczmarczyk

“…Abstract Background In the context of the ongoing German hospital reform, the newly introduced Federal Hospital Atlas aims to increase transparency regarding hospital structures and service quality. …”
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Approaches to clinical development of combination medicines in the Russian Federation and the Eurasian Economic Union in view of the requirements of the current legislation by A. V. Dobrovolskiy

“…In recent years, there has been an increasing interest in the development of combination medicines (fixed drug combinations) containing two or more active ingredients in a single dosage form. …”
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A Bibliometric Analysis of Mountain Research Literature on Journal of Mountain Research and Development: Current Situation and Future Directions by İsmet Güney, Merve Altundal Öncü, Burcu Göközkut, Mehmet Somuncu

“…Academic studies on mountains have increased since the 1990s. The aim of this study is to examine the current situation and development of the international literature on mountainous areas. …”
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Knowledge and Perception of Practicing Anesthetists on Current Techniques, Clinical Applications, and Limitations of Artificial Intelligence in Anesthesiology: An Indian Study by Manasij Mitra, Maitraye Basu, Amrita Ghosh, Ranabir Pal

“…Background: Artificial intelligence (AI) is increasingly gaining importance in modern medicine. Yet, there is a dearth of knowledge on what the anesthesiologists know and think about AI in context. …”
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Cost–consequence analysis of COPD treatment according to NICE and GOLD recommendations compared with current clinical practice in the UK by Jennifer K Quint, Helene Vioix, Toby Capstick, Sue Langham, Jennifer Cook, Antony Wright, Shamika de Silva

“…Savings were achieved overall despite a small increase in the rate of exacerbations due to the redistribution of certain patients currently undergoing triple inhaled therapy to therapies not containing inhaled corticosteroids.Conclusion Redistribution of patients with COPD from current clinical practice to treatment according to published recommendations would provide substantial cost savings over the first year.…”
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Integrating sequencing methods with machine learning for antimicrobial susceptibility testing in pediatric infections: current advances and future insights by Zhuan Zou, Zhuan Zou, Fajuan Tang, Fajuan Tang, Lina Qiao, Lina Qiao, Sisi Wang, Sisi Wang, Haiyang Zhang, Haiyang Zhang

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