Angiotensin-(1-7) protective effects in neurocognitive disorders: molecular mechanisms to therapeutic implications by Lillia C. Lucas, Katherine D. Kimbark, Victoria L. Vernail, Yuval Silberman, Amy C. Arnold

“…Current treatments for neurocognitive disorders have limited efficacy and typically focus on symptom attenuation rather than targeting intrinsic pathophysiology. …”
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Insomnia, Cognitive Impairment, or a Combination of Both, Alter Lipid Metabolism Due to Changes in Acylcarnitine Concentration in Older Persons by Selma Karime Castillo-Vazquez, Berenice Palacios-González, Marcela Vela-Amieva, Isabel Ibarra-González, Ricardo Morales, Paola García-delaTorre, Sergio Sánchez-García, Carmen García-Peña, Ricardo Reyes-Chilpa, Raúl Hernán Medina-Campos, Jessica Hernández-Pineda, Juan Carlos Gomez-Verjan, Nadia Alejandra Rivero-Segura

“…Results: Our results show that insomnia increases the concentration of acylcarnitines (C10, C8, C14, C12:1, C18:1 and C18) as compared to CI group, while older persons with CI show a decrease the concentration of the acylcarnitines C16, C10 and C8. …”
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Academic Motivation in English Online Classes: A Comparative Study of Universities in Malaysia and Indonesia by Suhaida Omar, Wan Yusoff Wan Shaharuddin, Nik Ahmad Farhan Azim @ Nik Azim, Noor Syamimie Mohd Nawi, Noraini Zaini, Wandi Syahfutra

“…This uniformity also implied that although English is a second language in Malaysia, and a foreign language in Indonesia, the undergraduates were not affected by their linguistics, and institutional contexts. This study has contributed towards the extension of the current knowledge involving undergraduates’ academic motivation towards learning English online and suggested that teachers could help to strategise students’ SRL and self-efficacy to increase their English language performances, particularly in the pandemic era. …”
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The Understanding of Willingness to Pay for Clean Drinking Water Through Extended Version of The Theory of Planned Behaviour by Zohaib Ali, Atta Ur Rehman, Muhammad Rafiq

“…The Structural Equation Modeling (SEM) is employed to validate the hypotheses of the research after recruiting 401 participants. The result of current study showed that TPB factors play a significant role in effecting households’ intention to pay (IP), which subsequently influences their WTP. …”
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Health insurance purchase intentions in the past decade: a systematic review and future research directions by Zhangwei Zheng, Hafizuddin-Syah B.A.M, Hafizah Omar Zaki, Qin Lingda Tan

“…Methods A systematic review was conducted using the TCM (theory-context-methodology) and ADO (antecedent-decision-outcome) frameworks. …”
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Effectiveness of laughter therapy with healthcare clowns on the mood of hospitalised adults by Yelsyn Mauricio Porras-Jiménez, Carmen Álvarez-Nieto, Karen Lizeth Romero-Granados, César Augusto Pinzón-Ordoñez, Isabel María López-Medina

“…Discussion: Current evidence supports laughter therapy with healthcare clowns as a tool to foster positive emotions, reduce negative psychological symptoms, and improve emotional well-being in various contexts, highlighting the importance of collaborative implementation with medical staff to strengthen well-being in healthcare settings. …”
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CHAC1: a master regulator of oxidative stress and ferroptosis in human diseases and cancers by Jiasen Sun, Hui Ren, Jiawen Wang, Xiang Xiao, Lin Zhu, Yanyan Wang, Lili Yang

“…CHAC1, an essential regulator of oxidative stress and ferroptosis, is increasingly recognized for its significant roles in these cellular processes and its impact on various human diseases and cancers. …”
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Stakeholder Partnerships in AI-Driven Economic Models for Sports Management by Akhmatov Makhmud, Shukurova Sayyora, Boymatov Khabib

“…The paper attempts to move forward research in AI-driven economic models for sports management from theoretical, empirical, and computational contexts to emerging stakeholder partnership frameworks that address current industry challenges. …”
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The Place of Global Issues in Foreign Language Classes from the Perspective of English Lecturers: A Critical Look by Kadriye Dimici

“…This situation necessitates the analysis of the integration of global issues in EFL contexts and the revelation of current practices by English lecturers. …”
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Strategies for adaptation of Russian commercial banks to innovative technologies by O. S. Solenaya

“…All banking innovations have a significant impact on the current business models of commercial banks, increasing the efficiency of their activities and at the same time the level of competition both in the banking sector and in the financial markets as a whole…”
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Cost-effectiveness of atezolizumab plus bevacizumab versus sorafenib as first-line therapy in unresectable hepatocellular carcinoma in the US and Chinese setting: a modelling compa... by Lei Wang, Lulu Liu, Yiling Ding, Qilin Zhang, Yamin Shu

“…In scenario analyses, the atezolizumab plus bevacizumab treatment becomes favourable when the cost of atezolizumab decreases to 67.85% and 18.45% of its original price in the USA and China, respectively.Conclusions The atezolizumab plus bevacizumab is unlikely to be cost-effective compared with sorafenib for patients with unresectable HCC in the context of the USA and China. …”
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Application of urinary peptide-biomarkers in trauma patients as a predictive tool for prognostic assessment, treatment and intervention timing by Gökmen Aktas, Felix Keller, Justyna Siwy, Agnieszka Latosinska, Harald Mischak, Jorge Mayor, Jan Clausen, Michaela Wilhelmi, Vesta Brauckmann, Stephan Sehmisch, Tarek Omar Pacha

“…CE-MS peptidome analysis identified 191 significantly altered peptides in severely injured patients. A consistent increase in the abundance of peptides from A1AT, AHSG, and HBA1 was observed, while peptides derived from PIGR and UROM were consistently decreased. …”
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Motivation to learn German as a foreign language: A systematic literature review by Asuman Yaprak

“…The findings show that motivation studies on German as a foreign language are primarily based on the second language motivational self-system model, the number of studies has increased with the paradigm shift, quantitative research methods and surveys are mainly used as data collection techniques, German is intensively researched together with other languages, and the aim is to determine what increases and decreases motivation by considering motivation levels and factors more.…”
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A framework for integrating neural development and social networks in adolescence by Jimmy Capella, Eva H. Telzer

“…Adolescence is a developmental period characterized by increasingly complex and influential peer contexts. Concurrently, developmental changes in neural circuits, particularly those related to social cognition, affective salience, and cognitive control, contribute to individuals’ social interactions and behaviors. …”
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Microsaccades in applied environments: Real-world applications of fixational eye movement measurements by Robert G Alexander, Stephen L Macknik, Susana Martinez-Conde

“…Here we present the state of the art in the practical applications of fixational eye movement research, examine its potential future uses, and discuss the benefits of including microsaccade measures in existing eye movement detection technologies. Current evidence supports the inclusion of fixational eye movement measures in real-world contexts, as part of the development of new or improved oculomotor assessment tools. …”
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Bleomycin: A worthy alternative by Gursev Sandlas, Paras Kothari, Parag Karkera, Abhaya Gupta

“…Complications of the therapy were few and far between. 2 patients developed fever after injection, one patients reported a transient increase in size of swelling, 2 patients have developed discoloration of the overlying skin and are currently being followed up for final outcome. …”
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Shifting of Distribution and Changing of Antibiotic Resistance in Gram-Positive Bacteria from Bile of Patients with Acute Cholangitis by Hao Y, Li L, Du W, Lu J

“…Yuqi Hao,1 Lianxin Li,2 Wenting Du,1 Jinshuai Lu1 1Department of General Internal Medicine, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, People’s Republic of China; 2Endoscopy Center, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, People’s Republic of ChinaCorrespondence: Jinshuai Lu, Department of General Internal Medicine, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, People’s Republic of China, Email lujinshuai@xjrmyy.comBackground: Gram-negative bacteria are the predominant pathogens responsible for biliary infections; however, the prevalence of Gram-positive bacteria is currently increasing. Investigating the bacterial spectrum and evolving antibiotic resistance patterns of Gram-positive bacteria is crucial for optimizing the management of acute cholangitis, particularly in the context of the global rise in antibiotic resistance.Methods: This retrospective analysis focused on Gram-positive bacteria isolated from the bile of patients undergoing biliary drainage with acute cholangitis at our hospital from January 1, 2018, to March 31, 2024. …”
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Problems in preparation of legally binding documents for oncological and palliative patients and their solutions by P. G. Gabay, B. Sh. Kamolov

“…To consider problems arising when an oncological or palliative patient decides to dispose of their property and to suggest solutions to these problems.Materials and methods. An analysis of the current normative legal acts and legal precedents in the Russian Federation in the context of property disposal by severely ill patients was performed. …”
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Internalized Stigma of Mental Illness and Its Relation with Self- Esteem and Social Support among Psychiatric Patients by Amany A. Mohamed

“… Context: Mentally ill patients challenging dual difficulties that are illness and stigma. …”
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Exploring efficacy of spiritual-based interventions (SBIs) in addressing depressive symptoms among cardiac patients in MENA region: a scoping review by Rizwana Amin

“…The results showed that SBIs are related to a decrease in depression symptomology and enhancement of psychological wellbeing. …”
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