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4321
Insomnia, Cognitive Impairment, or a Combination of Both, Alter Lipid Metabolism Due to Changes in Acylcarnitine Concentration in Older Persons
Published 2025-06-01“…Therefore, in the present study we aim to characterise metabolomic profiles of insomnia and CI alone in order to address a significant gap in current research regarding the pathways through which insomnia may lead to CI in older persons. …”
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4322
Hydrogen Loss on Venus Driven by Photochemistry
Published 2025-01-01“…Venus has experienced substantial H loss through hydrodynamic outflow in its early history, transforming from a warm and wet state to the current arid and scorching state. While Venus continues to lose H today, no consensus has been reached regarding the present dominant escape mechanisms. …”
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4323
Justificación del valor educativo de la Educación Física y el docente. ¿Qué profesional del deporte debe impartir la materia de Educación Física? ¿El Maestro/a y Profesor/a de Educ...
Published 2020-07-01“…This theoretical review aims at explaining and reflecting on what quality Physical Education and teachers’ professional competencies are, so as not to confuse it with school sports. Currently, there are several institutions that recommend a Quality Physical Education, and among other aspects they emphasize that this should increase up to 3 hours per week both in the stage of compulsory primary and secondary education. …”
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4324
Effects of intercropping with legume forage on the rhizosphere microbial community structure of tea plants
Published 2024-11-01“…ContextIntercropping in agriculture is crucial for addressing challenges in intensive tea farming. …”
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4325
Empowering older adults in medication safety
Published 2025-12-01“…The semi-structured questions were open ended and based on patient empowerment models and previous research assessing videos to increase knowledge and promote behavior change. Focus groups were recorded and transcribed verbatim. …”
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4326
Assessment of The Potential Interference and Conflict of Artificial Intelligence With Human Rights and Citizenship: Challenges and Solutions
Published 2025-03-01“…However, it should not be forgotten that no matter how advanced AI becomes, it must adhere to certain limitations in its personhood status, similar to legal entities. In the context of the legal status of artificial intelligence in Iran, there are currently no definitive regulations. …”
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4327
Improving outcomes for people with autism spectrum disorders by reducing mental health problems: the IAMHealth research programme including one RCT
Published 2025-05-01“…Factors contributing to this included beliefs about the causes of MHP and increased vulnerability with the context of a diagnosis of autism, knowledge of self-management and, based on prior experiences, a view that professional support or intervention was unavailable or inadequate. …”
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4328
Sustainable Design of a Tiny House: Using a Life Cycle Assessment Approach to Compare the Environmental Performance of Industrial and Earth-Based Building Systems
Published 2025-02-01“…The increased concerns about climate change, diminishing natural resources, and environmental degradation call for deep research into new environmentally friendly building systems that use natural or recycled materials. …”
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4329
Effects of ibrutinib and venetoclax on the expression of immune checkpoint molecules in leukemic blasts of patients with acute lymphoblastic leukemia
Published 2025-06-01“…By elucidating the precise underlying mechanisms, these drugs could emerge as promising therapeutic options, particularly in the context of combination therapy for ALL.…”
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4330
Improving Egg Quality in Tropical Environments: Assessing the Maize Meal Replacement by Wheat Bran and Soybean Oil in Laying Hen Diets
Published 2025-07-01“…ABSTRACT Background The use of wheat bran (WB) in the monogastric animal feed is limited due to its high fibre content and low energy contents. Objectives The current study evaluated the effect of replacing maize meal with WB, in the absence or presence of soybean oil, on egg quality and economic performance indicators. …”
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4331
A novel therapeutic approach targeting PD-L1 in HNSCC and bone marrow-derived mesenchymal stem cells hampers pro-metastatic features in vitro: perspectives for blocking tumor-strom...
Published 2025-02-01“…Abstract Background Current conventional treatment regimens for head and neck squamous cell carcinoma (HNSCC), are poorly effective because of the emergence of resistance mechanisms. …”
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4332
Tuberculosis mortality and drug resistance among patients under TB treatment before and during COVID-19 in Burundi: a case–control study
Published 2025-05-01“…Conclusion TB mortality increased during the COVID-19 pandemic, particularly among MDR-TB patients. …”
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4333
MODERN APPROACHES TO DIAGNOSTICS AND TREATMENT OF DENTAL TRAUMA
Published 2020-12-01“…The current approach to the treatment of dental trauma is focused on less invasive and more biologically oriented methods of treatment of hard dental tissues, pulp, periodontal ligament and alveolar bone. …”
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4334
Isolation of mitogen-activated protein kinase SlMAPK12 gene and characterization of its expression pattern in Solanum lycopersicum
Published 2012-09-01“…As we know, current research on tomato (Solanum lycopersicum L.) …”
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4335
Advancing the therapeutic effectiveness of paclitaxel in chronic lymphocytic leukemia through the simultaneous inhibition of NOTCH1 and SF3B1
Published 2025-03-01“…Overexpression of the splicing factor 3b subunit 1 (SF3B1) and neurogenic locus notch homolog protein 1 (NOTCH1) factors is typically found in chronic lymphocytic leukemia (CLL), leading to the development of chemotherapy resistance. Objective The current investigation aims to evaluate the chemosensitivity of CLL cells by blocking NOTCH1 and SF3B1 using chitosan lactate (CL) nanoparticles (NPs). …”
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4336
Immunological and physiological changes of exercise-released lactate on tumors: an important and new research window
Published 2024-12-01“…In the cancer immune cycle, the immune checkpoint PD-1 and its ligand PD-L1 collaborate to facilitate immune escape and promote tumor progression (Keir et al., 2008). In this context, a study revealed that lactate can enhance the expression of PD-L1 on tumor cells, suggesting that lactate may have a protective effect against tumors by increasing PD-L1 expression (Feng et al., 2017). …”
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4337
The impact of electronic cigarette smoking on periodontal status and proinflammatory cytokine levels: a cross-sectional study
Published 2025-05-01“…Abstract Background E-cigs(E-cigs) use is increasing worldwide. Recent studies suggest that E-cigs contain harmful elements that could lead to adverse oral health outcomes. …”
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4338
Bionomics of Aedes mosquito species in three eco-epidemiological settings of Cameroon and their susceptibilities profiles to insecticides
Published 2025-03-01“…After emergence and morphological identification, F0 and F1 of Aedes aegypti and Aedes albopictus progeny will be used to assess the current phenotypic resistance status to the commonly used insecticides using WHO bioassays and mortality rates were assess according to the different insecticides tested. …”
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4339
Improved Mechanical Performances of Hastelloy C276 Composite Coatings Reinforced with SiC by Laser Cladding
Published 2024-12-01“…The self-corrosion potential measured at 315 mV, with a self-corrosion current density of 6.884 × 10⁻<sup>6</sup> A/cm<sup>2</sup>, and the electrochemical charge-transfer resistance was approximately 25 times that of the substrate and 1.26 times that of the 0 wt%. …”
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4340
Construction of Modified Mesoporous Graphite Phase Carbon Nitride Material and Its Photocatalytic U(Ⅵ) Reduction Performance
Published 2025-03-01“…Consequently, the uranium-containing wastewater produced poses significant and substantial threats to environmental safety and public health. …”
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