Bleomycin: A worthy alternative by Gursev Sandlas, Paras Kothari, Parag Karkera, Abhaya Gupta

“…Complications of the therapy were few and far between. 2 patients developed fever after injection, one patients reported a transient increase in size of swelling, 2 patients have developed discoloration of the overlying skin and are currently being followed up for final outcome. …”
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The role of community health workers in addressing the global burden of ear disease and hearing loss: a systematic scoping review of the literature by James O'Donovan, Misha Verkerk, Niall Winters, Shelly Chadha, Mahmood F Bhutta

“…We performed a systematic scoping review to identify evidence on how CHWs are currently deployed in the prevention, screening, diagnosis, treatment and management of ear disease and hearing loss; methods to train and support CHWs in this context; and cost-effectiveness of CHWs.Methods We performed a systematic search of the literature from September 1978 to 18 March 2018 from 11 major databases and the grey literature.Results We identified 38 original studies that met the inclusion criteria, taking place across South Asia (n=13), Oceania (n=7), North America (n=7), South America (n=6) and Africa (n=5). 23 studies showed CHWs can increase community participation in screening. …”
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Shifting of Distribution and Changing of Antibiotic Resistance in Gram-Positive Bacteria from Bile of Patients with Acute Cholangitis by Hao Y, Li L, Du W, Lu J

“…Yuqi Hao,1 Lianxin Li,2 Wenting Du,1 Jinshuai Lu1 1Department of General Internal Medicine, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, People’s Republic of China; 2Endoscopy Center, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, People’s Republic of ChinaCorrespondence: Jinshuai Lu, Department of General Internal Medicine, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, People’s Republic of China, Email lujinshuai@xjrmyy.comBackground: Gram-negative bacteria are the predominant pathogens responsible for biliary infections; however, the prevalence of Gram-positive bacteria is currently increasing. Investigating the bacterial spectrum and evolving antibiotic resistance patterns of Gram-positive bacteria is crucial for optimizing the management of acute cholangitis, particularly in the context of the global rise in antibiotic resistance.Methods: This retrospective analysis focused on Gram-positive bacteria isolated from the bile of patients undergoing biliary drainage with acute cholangitis at our hospital from January 1, 2018, to March 31, 2024. …”
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The Influence of Parameterized Shallow Convection on Trade‐Wind Clouds and Circulations in the HARMONIE‐AROME Mesoscale Model by A. C. M. Savazzi, L. Nuijens, W. deRooy, A. P. Siebesma

“…Abstract Mesoscale numerical weather prediction models currently operate at kilometer‐scale and even sub‐kilometer‐scale resolutions. …”
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Investigation of Heat and Mass Transfer in the Process of Fuel Preparation from Biomass Particles with High Moisture by A. V. Mitrofanov, O. B. Kolibaba, R. N. Gabitov, D. A. Dolinin, S. V. Vasilevich

“…Currently, in a number of countries an urgent task for development of fuel and energy complexes is to increase the share of generation by involving solid fuels in circulation. …”
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Pilot observational cohort study to determine whether waveform and flow traces from mechanical insufflation–exsufflation (MI-E) can be used to identify laryngeal responses to MI-E... by Stephanie K Mansell, Swapna Mandal, Amar Shah, Francesca Gowing, Rhiannon Parry, Charlotte Greenfield, Yogesh Bhatt

“…Currently, the only method for assessing this is via nasal endoscopy while using MI-E. …”
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Geographical accessibility of emergency neonatal care services in Ethiopia: analysis using the 2016 Ethiopian Emergency Obstetric and Neonatal Care Survey by Andrew Hayen, Getiye Dejenu Kibret, Daniel Demant

“…Addis Ababa and the Hareri regional state had full access (100% coverage) to EmNeC services within 2 hours travel time, while the Afar (15.3%) and Somali (16.3%) regional states had the lowest access.Conclusions The physical access to EmNeC services in Ethiopia is well below the universal health coverage expectations stated by the United Nations. Increasing the availability of EmNeC to health facilities where routine delivery services currently are taking place would significantly increase physical access. …”
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Rate of detection of endocrine diseases in children in the practice of a family doctor by I. I. Redko, E. N. Chakmazova

“…Currently, there is a tendency to increase the prevalence of endocrine pathologists in all age groups of the children's population of Ukraine. …”
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Effect of dietary Cucurbita pepo extract on performance, hemato-immunological parameters, immune-related gene expression and bacterial resistance in rainbow trout, Oncorhynchus myk... by Kaveh Vakili, Amir Eghbal Khajehrahimi, Behnam Salimi, Shapour Kakoolaki, Arman Ghorbanzadeh

“…The highest hematocrit and hemoglobin contents were associated with the diet containing 4 % CPE. Similarly, dietary 4 % of CPE effectively increased lysozyme activity, and immunoglobulin content compared to the control diet. …”
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Cosensitization Properties of Glutathione-Protected Au25 Cluster on Ruthenium Dye-Sensitized TiO2 Photoelectrode by Kazuya Nakata, Sho Sugawara, Wataru Kurashige, Yuichi Negishi, Morio Nagata, Satoshi Uchida, Chiaki Terashima, Takeshi Kondo, Makoto Yuasa, Akira Fujishima

“…When pH < 5, the IPCE increases with pH. Conversely, the IPCE decreases with pH when pH > 7. …”
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MSC-derived extracellular vesicles: Precision miRNA delivery for overcoming cancer therapy resistance by Ahsas Goyal, Muhammad Afzal, Kavita Goyal, Subbulakshmi Ganesan, Mukesh Kumari, S. Sunitha, Aniruddh Dash, Suman Saini, Mohit Rana, Gaurav Gupta, Haider Ali, Ling Shing Wong, Vinoth Kumarasamy, Vetriselvan Subramaniyan

“…Carrying a variety of molecules, including microRNAs, small interfering RNAs, long non-coding RNAs, proteins, lipids, and DNA, these vesicles are positioned as promising cancer treatment options. Current studies have increasingly investigated the capacity of microRNAs as a strategic approach for combating malignancy. …”
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THE VALUE OF THE RUSSIAN NATIONAL REGISTRY OF PATIENTS WITH ANCA-ASSOCIATED SYSTEMIC VASCULITIS AS AN INNOVATIVE TOOL OF PERSONALIZED INDUCTION AND MAINTENANCE THERAPY by T. V. Beketova

“…Rational and personalized maintenance of a delicate balance between the use of an evidence-based  treatment protocol,  which is sufficient to secure sustainable suppression of the activity of ANCA-SV, and the simultaneous containment of the risk of treatment adverse events are the mainstay for successful therapy.In response to the increased need for improved approaches to managing patients with ANCA-SV, the V.A. …”
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Tomato seed extract promotes health of the gut microbiota and demonstrates a potential new way to valorize tomato waste. by Jenni Firrman, Adrienne Narrowe, LinShu Liu, Karley Mahalak, Johanna Lemons, Pieter Van den Abbeele, Aurélien Baudot, Stef Deyaert, Yanfang Li, Yuanhang Yao, Liangli Yu

“…The current effort to valorize waste byproducts to increase sustainability and reduce agricultural loss has stimulated interest in potential utilization of waste components as health-promoting supplements. …”
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Targeted disruption of LDLR causes hypercholesterolemia and atherosclerosis in Yucatan miniature pigs. by Bryan T Davis, Xiao-Jun Wang, Judy A Rohret, Jason T Struzynski, Elizabeth P Merricks, Dwight A Bellinger, Frank A Rohret, Timothy C Nichols, Christopher S Rogers

“…Recent progress in engineering the genomes of large animals has spurred increased interest in developing better animal models for diseases where current options are inadequate. …”
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Methylchloroisothiazolinone/Methylisothiazolinone and Methylisothiazolinone Sensitivity in Hungary by Györgyi Pónyai, Ilona Németh, Erzsébet Temesvári

“…A further increase of MI hypersensitivity might be expected in the future as products containing MI are still widely available.…”
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Tim-3 is dispensable for allergic inflammation and respiratory tolerance in experimental asthma. by Carolin Boehne, Ann-Kathrin Behrendt, Almut Meyer-Bahlburg, Martin Boettcher, Sebastian Drube, Thomas Kamradt, Gesine Hansen

“…T cell immunoglobulin and mucin domain-containing molecule-3 (Tim-3) has been described as a transmembrane protein, expressed on the surface of various T cells as well as different cells of innate immunity. …”
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Investigation of the Impact of Chemical Modifications on the Photostability of Polymethyl Methacrylate by Hanan A. Ibraheem, Gamal A. El-Hiti, Emad Yousif, Dina S. Ahmed, Hassan Hashim, Benson M. Kariuki

“…Polymeric chain modifications have proved to be efficient in increasing the photostability of materials. The current work deals with the surface functionalization of polymethyl methacrylate (PMMA) by incorporating organotin moieties on the polymer backbone. …”
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Presentation of Financial Assets in Russian Macroeconomic Statistics by V. N. Salin, M. V. Vakhrameeva, O. Yu. Sitnikova

“…The purpose of the study. Currently, much attention is paid to the collection, presentation and analysis of data on the volume, structure and dynamics of economic assets. …”
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Burnout and its Factors in Healthcare Workers Involved in Providing Health Care for Patients With COVID-19 at Different Stages of the Pandemic by A. B. Kholmogorova, S. S. Petrikov, A. Y. Suroyegina, O. Y. Mikita, A. A. Rakhmanina, A. P. Roy

“…Abstract. In the context of the pandemic, when healthcare professionals are forced to work under extreme stress and an increased threat of infection, research on professional burnout and emotional maladjustment of medical workers is gaining particular relevance around the world.Aim of study. …”
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Load Forecasting in Electrical Grids: Analysis of Methods and their Trends by Kyryk V.V., Shatalov Y.O.

“…The results show that, although increasingly complex models are being developed, their accuracy gain remains inconsistent in different application contexts, provided that a single-type architecture is used. …”
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