Hydroxyapatite-filled osteoinductive and piezoelectric nanofibers for bone tissue engineering by Frederico Barbosa, Fábio F. F. Garrudo, Paola S. Alberte, Leonor Resina, Marta S. Carvalho, Akhil Jain, Ana C. Marques, Francesc Estrany, Frankie J. Rawson, Carlos Aléman, Frederico Castelo Ferreira, João C. Silva

“…The biological cues provided by the HAp nanoparticles enhanced the osteogenic differentiation of seeded human mesenchymal stem/stromal cells (MSCs) as observed by the increased ALP activity, cell-secreted calcium deposition and osteogenic gene expression levels observed for the HAp-containing fibers. …”
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Didgital-art цінних паперів by Oleh Kardash, Viktor Chelombitko

“…Scientific novelty. The current state of digital art is analyzed. Its branches have been studied and the connections with graphic design have been determined. …”
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Experimental study on tensile performance of horizontal joint bolted connections in fully assembled modular construction reinforced concrete by RAN Mingming, KOU Guangyun, XIONG Feng, ZHANG Dongdong, LI Wei

“…In Mode IV, when the load was increased to 134.2 kN, abrupt fracture failure of the concrete at the cross-section above the operating hand-hole of the specimen was observed, with limited cracking. …”
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Research hotspots and trends in the application of diffusion tensor imaging in ischemic stroke: a bibliometric analysis (2003–2024) by Xu Chen, Xu Chen, Meifang Liu, Xiaolin Yang, Mengqi Yue, Haocheng Yu, Haiqiang Wang, Zirong Wang, Jing Shi, Jing Shi, Yong Qiu

“…However, the current study still needs to strengthen cross-regional cooperation, and higher quality and broader research is still necessary to lay the foundation for reaching the consensus of various experts.…”
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Enhanced Broad-Spectrum Efficacy of an L2-Based mRNA Vaccine Targeting HPV Types 6, 11, 16, 18, with Cross-Protection Against Multiple Additional High-Risk Types by Kosuke Tsukamoto, Akio Yamashita, Masatoshi Maeki, Manabu Tokeshi, Hirotatsu Imai, Akira Fukao, Toshinobu Fujiwara, Koji Okudera, Nobuhisa Mizuki, Kenji Okuda, Masaru Shimada

“…Results: We identified that a construct containing E01 (a 5′-untranslated region) and SL2.7 (a poly(A) polymerase recruitment sequence) significantly increased protein expression. …”
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Improved lubricating and corrosion resistance of MAO coatings on ZK61 Mg alloy by co-doping with graphite and nano-zirconia by Chao Yang, Liyuan Sheng, Chaochao Zhao, Pinghu Chen, Wentai Ouyang, Daokui Xu, Yufeng Zheng, Paul K. Chu

“…Compared with doping with a single element, co-doping increases the content of ZrO2 and graphite in the MAO coating. …”
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Hybrid surface layers with antibacterial and anti-inflammatory activity for implants materials by Mariia A. Piatkova, Konstantine V. Nadaraia, Arina I. Ponomarenko, Igor V. Manzhulo, Mariia S. Gerasimenko, Arina I. Pleshkova, Evgeny A. Belov, Igor M. Imshinetskiy, Ksenia A. Fomenko, Ivan S. Osmushko, Aleksey G. Kozlov, Sergey V. Gnedenkov, Dmitry V. Mashtalyar

“…Currently, there is an essential need for bioresorbable bone implants with antibacterial, anti-inflammatory properties as well as osteoinductivity. …”
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Highly sensitive multiplex PCR for convenient quantification and differentiation of canine Oomycota pathogens: Pythium insidiosum, Lagenidium giganteum f. caninum, and Paralagenidi... by Asfiha Tarannum, Subarna Barua, Leonel Mendoza, Raquel Vilela, Priscilla Barger, Terri Hathcock, Amelia White, Kelly Chenoweth, Chengming Wang

“…Interestingly, the developed multiplex Oomycota PCR revealed that 45.5% (40/88) of serum samples positive for anti-Pythium antibody contained Pythium DNA. Additionally, among 24 suspected anti-Pythium antibody-positive samples, 54.2% (13/24) tested positive for Pythium DNA, while 8.3% (2/24) contained Lagenidium DNA. …”
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Mycochemistry, antioxidant, anticancer activity, and molecular docking of compounds of F12 of ethyl acetate extract of Astraeus asiaticus with BcL2 and Caspase 3 by Swapan Kumar Ghosh, Koushik Pandey, Madhuparna Ghosh, Pradip Kumar Sur

“…Abstract Globally the current research is going for cancer disease management by different strategies as frequency and severity of this disease are increasing day by day. …”
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Helminth Coinfections Modulate Disease Dynamics and Vaccination Success in the Era of Emerging Infectious Diseases by Brice Armel Nembot Fogang, Linda Batsa Debrah, Michael Owusu, George Agyei, Julia Meyer, Jonathan Mawutor Gmanyami, Manuel Ritter, Kathrin Arndts, Derrick Adu Mensah, Tomabu Adjobimey, Achim Hörauf, Alexander Yaw Debrah

“…Helminth infection can also negatively impact vaccine efficacy by suppressing B cell activity, reducing antibody levels, and decreasing vaccine effectiveness against infectious diseases. …”
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Combined single- and dual-energy CT workflow for dose calculation in radiotherapy by Hella Sand, Jens Edmund, Ane Appelt, Patrick Wohlfahrt, Vicki Trier Taasti, Laurids Østergaard Poulsen, Jimmi Søndergaard, Martin Skovmos Nielsen

“…Background and purpose: Dual-energy computed tomography (DECT) is increasingly used in radiotherapy delineation due to its enhanced soft tissue contrast. …”
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Gene Editing Anxiety by Angelo Osofsky

“…Health and Genetic Risks of Germline Editing Editing the human germline to prevent psychiatric disorders poses serious health risks to individuals. Currently, scientists warn that genetically altering the human genome can result in off-target mutations that increase the risk of disease. …”
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Development of a composite material based on a processed product of agricultural crop by Zura Yessimsiitova, Murat Toktar, Alibek Mutushev, Aizhan Konysbayeva, Gulmira Yeltay, Aliya Bagybekkyzy, Akmaral Kydyrkhanova, Damira Yussayeva

“…Anthropogenic influence on the environment contributes to an increase in the content of heavy metals in soils. This is facilitated by the developed industrial sector, high population density and large-scale growth of urban areas. …”
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Research progress on the control of reactive elements in remelted ingots during the electroslag remelting process by Shengchao DUAN, Lifeng ZHANG

“…Additionally, the physical parameters of the slag system play a crucial role in determining the surface quality and solidification characteristics of the ingots. Current research on the physical parameters of remelting slag systems containing TiO2, SiO2, B2O3, and rare earth oxides has primarily focused on viscosity and crystallization behavior. …”
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Mechanical Load‐Induced Upregulation of Talin2 through Non‐Canonical Deubiquitination of OTUB1 Drives Facet Joint Osteoarthritis Pathogenesis by Yizhen Huang, Heng Sun, Haojie Chen, Xiangpeng Wang, Junduo Zhao, Yang Jiao, Hongyi Zhou, Haoyu Cai, Jiafeng Dai, Xuan Huang, Weiyun Chen, Jianxiong Shen

“…Abstract Facet joint osteoarthritis (FJOA) is a prevalent degenerative condition in the aging population; however, the underlying pathophysiological mechanisms remain poorly understood and current therapeutic strategies remain limited to palliative pain management. …”
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Fastest Prostate Cancer Prediction on Whole-Mount Pathological Slides Using Self-Reform Multilayer Transformer by Linjie Xu, Xiaotian Yu, Haoming Luo, Jili Wang, Wenjie Liang, Jing Zhang, Zunlei Feng, Cheng Lu, Xiuming Zhang

“…Moreover, pixels in each whole-mount slide of PCa are increased by approximately <inline-formula> <tex-math notation="LaTeX">$4\sim 9$ </tex-math></inline-formula> times, therefore containing more information for diagnosis. …”
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What happens between first symptoms and first acute exacerbation of COPD – observational study of routine data and patient survey by Alex Bottle, Alex Adamson, Xiubin Zhang, Benedict Hayhoe, Jennifer K Quint

“…Most patients were offered the flu jab. Older patients, current smokers and those with other conditions such as heart failure had higher risk of an acute exacerbation. …”
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Incidence and trends of limb amputation in first nations and general population in Saskatchewan, 2006-2019. by Samuel Kwaku Essien, Gary Linassi, Margaret Larocque, Audrey Zucker-Levin

“…Overall and primary LA rates for the GP Group declined 0.7% and 1.0%, while subsequent LA increased 0.1%. An increased LA rate for all categories (overall 4.9%, primary 5.1%, and subsequent 4.6%) was identified in the RI group. …”
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C18:0 GM3 ganglioside’s efficacy in LPS-induced parkinsonism: neuroprotection, inflammatory inhibition and gliosis mitigation by Tsung-Ta Liu, Cheng-Tsung Liu, I-Hsun Li, Yu-Chieh Chu, Hao-Yuan Hung, Chuang-Hsin Chiu, Ta-Kai Chou, Shiao-Yun Li, Tin-An Wang, Jui-Hu Shih

“…Abstract Background Parkinson’s disease (PD) is an incurable neurological disorder, and current pharmacological therapies primarily address symptoms without halting disease progression. …”
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Assessment of Nurse's Health Promotion of Their Lifestyles at Al-Kut City Hospitals, Iraq by Ammar A. Okab

“…Poor lifestyle choices lead to chronic diseases or even death. It increases healthcare costs in a time of economic downsizing. …”
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