Monitoring of hepatitis E virus infection and replication by functional tagging of the ORF2 protein by Maliki Ankavay, Nathalie Da Silva, Angela Pollán, Noémie Oechslin, Katja Dinkelborg, Patrick Behrendt, Darius Moradpour, Jérôme Gouttenoire

“…Understanding of the mechanisms underlying productive HEV infection remains incomplete and would benefit from technological advances improving current model systems. Methods: We exploited transposon-mediated random insertion and selection of viable clones to identify sites in the HEV open reading frame 2 (ORF2) protein, corresponding to the viral capsid, allowing for the insertion of reporter sequences in a functional context. …”
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Unlocking the potential of global greenhouse gas mitigation by reducing food loss and waste by Suraj Negi, Liang-Shih Fan, Hyunook Kim, Taira Hidaka, Aishwarya Rani, Shu-Yuan Pan

“…Food loss and waste (FLW) are significant yet under-addressed contributors to global greenhouse gas (GHG) emissions, and the effectiveness of current FLW mitigation policies and valorization technologies remains insufficiently explored. …”
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The SahulCHAR collection: a palaeofire database for Australia, New Guinea, and New Zealand by E. Rehn, H. Cadd, S. Mooney, T. J. Cohen, H. Munack, A. T. Codilean, M. Adeleye, K. K. Beck, M. Constantine IV, C. Gouramanis, J. M. Hanson, P. J. Jones, A. P. Kershaw, L. Mackenzie, M. Maisie, M. Mariani, K. Matley, D. McWethy, K. Mills, P. Moss, N. R. Patton, N. R. Patton, C. Rowe, J. Stevenson, J. Tibby, J. Wilmshurst

“…<p>Recent global fire activity has highlighted the importance of understanding fire dynamics across time and space, with records of past fire (palaeofire) providing valuable insights to inform us on current and future management challenges. New records from the recent increase in palaeofire studies from Australia and surrounds have not been captured in any database for broader comparisons, and Australasia is poorly represented in current international databases used for global modelling of palaeofire trends. …”
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Temporal and Spatial Evolution and Driving Force Analysis of Water Conservation Function in Yunnan Province Based on Climate and Land Use Change by LIU Fengru, ZHAO Junsan, LIN Yilin, CHEN Guoping, ZHANG Longjiang, PENG Sufen

“…The framework can predict land use change and assess water conservation in the context of future climate change and different economic developments. …”
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Climate change reduces warming potential of nitrous oxide by an enhanced Brewer‐Dobson circulation by Daniela Kracher, Christian H. Reick, Elisa Manzini, Martin G. Schultz, Olaf Stein

“…N2O is a potent greenhouse gas and the most relevant currently emitted ozone‐depleting substance. Here we examine the implications of a reduced N2O lifetime in the context of climate change. …”
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Not All Antibodies Are Created Equal: Factors That Influence Antibody Mediated Rejection by Carrie L. Butler, Nicole M. Valenzuela, Kimberly A. Thomas, Elaine F. Reed

“…This review highlights what is currently known about the clinical context of pre and posttransplant antibodies, antibody characteristics that influence AMR, and the paths after donor specific antibody production (no rejection, subclinical rejection, and clinical dysfunction with AMR).…”
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Molecular mechanisms underlying Tao-Hong-Si-Wu decoction treating hyperpigmentation based on network pharmacology, Mendelian randomization analysis, and experimental verification by Jun Chen, Wenyi Ye

“…Context Hyperpigmentation, a common skin condition marked by excessive melanin production, currently has limited effective treatment options.Objective This study explores the effects of Tao-Hong-Si-Wu decoction (THSWD) on hyperpigmentation and to elucidate the underlying mechanisms.Materials and methods We employed network pharmacology, Mendelian randomization, and molecular docking to identify THSWD’s hub targets and mechanisms against hyperpigmentation. …”
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Development Process and Characteristics Study of Tree Line Discharge in 10 kV Overhead Power Lines by XU Huikai, HUANG Xiaolong, YANG Chunlan, CHEN Tianxiang, YANG Nongchao, CHEN Long

“…The moisture distribution within the tree affected the development of current channels. During the transition from the contact and warming stage to the water evaporation stage, the passage of electric current through the tree shifted from the sapwood to the vascular cambium due to a temperature increase that enabled water migration from the tree. …”
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New Safety Management System for Pasta Production by Fazullina Oliya F., Smirnov Stanislav O.

“…The developed FSMS gives new market options and increases the loyalty of consumers and business partners. …”
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Visualization of the Lamina Cribrosa of Sclera Using Optical Coherence Tomography. The Opportunities and Prospects for Diagnostics (Review) by V. V. Kurenkov, V. S. Klyuganov, N. V. Kuznetsova, K. V. Chinenova, M. E. Konovalov, M. D. Pozharitsky

“…The ratio of collagen fibers I, II and IV types, as well as elastin protein provide support and elastic properties of the lamina cribrosa. Increased intraocular pressure on the background of involutional changes in the composition of the connective tissue of the lamina cribrosa leads to deformation of the latter, compression of nerve fibers passing through the holes in the lamina cribrosa and violation of the axoplasmic current. …”
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Response of ornamental plants to salinity: impact on species-specific growth, visual quality, photosynthetic parameters, and ion uptake by Zirui Wang, Zirui Wang, Shital Poudyal, Kelly Kopp, Yunhua Zhang

“…Reclaimed water typically contains elevated salt levels that can induce salt stress. …”
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Aquaculture as a source of functional food by A. V. Zhigin, M. V. Sytova, Yu. I. Yesavkin

“…Current state of functional nutrition is analyzed. …”
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Investigating the Effect of Wood Charcoal Dust as Partial Replacement for Cement in Plain Concrete. by Akankunda, Lindah

“…The increasing demand for cement, driven by the current construction boom, has escalated its production, making it a critical component in concrete. …”
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The impacts of climate variability on conflict risk in conflict-prone regions worldwide by Xiaolan Xie, Fangyu Ding, Mengmeng Hao, Jun Zhuo, Shuai Chen, Jiajie Wu, Jiping Dong, Kai Sun, Qian Wang, Dong Jiang

“…The meta-analysis shows that one standard positive temperature deviation (1σ), increased extreme precipitation, and decreased precipitation induce 0.81 %, 2.53 %, and 1.04 % increment respectively in the risk of conflict incidence, as well as 1.12 %, 2.55 %, and 1.15 % decrement respectively in the risk of conflict onset. …”
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Application of IVDr NMR spectroscopy to stratify Parkinson’s disease with absolute quantitation of blood serum metabolites and lipoproteins by Georgy Berezhnoy, Gyuntae Bae, Leonie Wüst, Claudia Schulte, Claire Cannet, Isabel Wurster, Milan Zimmermann, Alexander Jäck, Eike Jakob Spruth, Julian Hellmann-Regen, Sandra Roeske, Dominik Pürner, Wenzel Glanz, Fabian Maass, Felix Hufschmidt, Ingo Kilimann, Elisabeth Dinter, Okka Kimmich, Anna Gamez, Johannes Levin, Josef Priller, Oliver Peters, Michael Wagner, Alexander Storch, Paul Lingor, Emrah Düzel, Christoph van Riesen, Ullrich Wüllner, Stefan Teipel, Björn Falkenburger, Mathias Bähr, Inga Zerr, Gabor C. Petzold, Annika Spottke, Patricia Rizzu, Frederic Brosseron, Hartmut Schäfer, Thomas Gasser, Christoph Trautwein

“…Abstract The challenge of early detection and stratification in Parkinson’s disease (PD) is urgent due to the current emergence of mechanism-based disease-modifying treatments. …”
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Polyphenols of Mulberry White (Morus alba L.) Leaves as a Source of Functional Food: A Review by Hagar F. Forsan, Menatalla R. Fayed, Noureldin M. Farahat, Walaa M. Gabr, Ezzeldeen M. Alswerky, Asmaa E. Abd El-Hak, Mohamed A. Fouda, Mennat-Allah Safwat

“…However, this residue in mulberry leaves naturally contains high levels of bioactive compounds, especially polyphenols. …”
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Characterization, Conservation, and Breeding of Winter Squash (<i>Cucurbita moschata</i> Duchesne): Case Study of the Collection Maintained at the Federal University of Viçosa Vege... by Derly José Henriques da Silva, Ronaldo Silva Gomes, Ronaldo Machado Júnior, Cleverson Freitas de Almeida, Rebeca Lourenço de Oliveira, Dalcirlei Pinheiro Albuquerque, Santina Rodrigues Santana

“…Studies on <i>C. moschata</i> germplasm have reported high variability, particularly in Brazil. Currently, Brazil maintains six <i>Cucurbita</i> germplasm collections, kept in research and teaching institutions. …”
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Insomnia, Cognitive Impairment, or a Combination of Both, Alter Lipid Metabolism Due to Changes in Acylcarnitine Concentration in Older Persons by Selma Karime Castillo-Vazquez, Berenice Palacios-González, Marcela Vela-Amieva, Isabel Ibarra-González, Ricardo Morales, Paola García-delaTorre, Sergio Sánchez-García, Carmen García-Peña, Ricardo Reyes-Chilpa, Raúl Hernán Medina-Campos, Jessica Hernández-Pineda, Juan Carlos Gomez-Verjan, Nadia Alejandra Rivero-Segura

“…Results: Our results show that insomnia increases the concentration of acylcarnitines (C10, C8, C14, C12:1, C18:1 and C18) as compared to CI group, while older persons with CI show a decrease the concentration of the acylcarnitines C16, C10 and C8. …”
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Antioxidative and Antimelanoma Effects of Various Tea Extracts via a Green Extraction Method by Yihui Chen, Jyun-Yin Huang, Yichi Lin, I-Fan Lin, Yi-Ru Lu, Li-Heng Liu, Hui-Min David Wang

“…Tea (Camellia sinensis) contains high level of antioxidant elements and is a well-known beverage consumed worldwide. …”
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The State and the Prospects of the Development of Innovative Activity in the Russian Federation in the XXI Century by A. A. Varushchenko, N. A. Vladimirov

“…Global spending on innovation continues to grow, and the share of business in it is increasing. The relevance of this topic is also due to the acceleration of the processes of digital transformation of the Russian and international economy, which is why the need to create conditions for innovation, information and communication technologies is increasing. …”
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