What happens between first symptoms and first acute exacerbation of COPD – observational study of routine data and patient survey by Alex Bottle, Alex Adamson, Xiubin Zhang, Benedict Hayhoe, Jennifer K Quint

“…Most patients were offered the flu jab. Older patients, current smokers and those with other conditions such as heart failure had higher risk of an acute exacerbation. …”
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Disease progression & treatment need in sub-genotype C4 hepatitis B infection: a retrospective cohort study in the Northern Territory, Australia by Genevieve E. Martin, Kelly Hosking, Kelly Banz, Catherine Gargan, Geoff Stewart, Belinda Greenwood-Smith, Penelope Ramsay, Jaclyn Tate-Baker, Christine Connors, Paula Binks, Melita McKinnon, Prashanti Manchikanti, George Garambaka Gurruwiwi, Nicole Allard, Ashleigh Qama, Jessica Michaels, Emily Vintour-Cesar, Robert Batey, Catherine Marshall, Peter Nihill, Tammy-Allyn Fernandes, Karen Fuller, Steven Y. C. Tong, David Boettiger, Benjamin Cowie, Joshua S. Davis, Sarah Mariyalawuy Bukulatjpi, Jane Davies, on behalf of the Hep B PAST Partnership

“…Only 6·7% of untreated individuals were treatment eligible under current guidelines. Using the 2024 World Health Organisation guidelines, this increased to 50% due mostly to fibrosis and population prevalence of diabetes. …”
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Self-generated temperature gradient under uniform heating in p–i–n junction carbon nanotube thermoelectric generators by Oga Norimasa, Ryota Tamai, Hiroto Nakayama, Yoshiyuki Shinozaki, Masayuki Takashiri

“…The output voltage and current of the SWCNT-TEG increased with increasing temperature. …”
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Polyphenols of Mulberry White (Morus alba L.) Leaves as a Source of Functional Food: A Review by Hagar F. Forsan, Menatalla R. Fayed, Noureldin M. Farahat, Walaa M. Gabr, Ezzeldeen M. Alswerky, Asmaa E. Abd El-Hak, Mohamed A. Fouda, Mennat-Allah Safwat

“…However, this residue in mulberry leaves naturally contains high levels of bioactive compounds, especially polyphenols. …”
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Alpha Helices Are More Robust to Mutations than Beta Strands. by György Abrusán, Joseph A Marsh

“…The rapidly increasing amount of data on human genetic variation has resulted in a growing demand to identify pathogenic mutations computationally, as their experimental validation is currently beyond reach. …”
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Comprehensive analysis of the mechanisms conferring resistance to phenamacril in the Fusarium species by Alexander Dumbai Joe, Runze Liu, Xiao Luo, Ruqiya Syed, Farhan Aslam, Zhenying Luo, Zhitian Zheng

“…We emphasize the importance of continued research and integrating different approaches to monitoring and managing drug-resistant Fusarium spp. populations. Integrating current inventions to inform strategies for sustainable disease control practices, and increase plant health, and yield will contribute to ongoing global efforts to achieve food and nutritional sustainability for the world's rapidly growing population while ensuring the effectiveness of the fungicidal product.…”
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Berberis lycium: A Miracle Medicinal Plant with Multifaceted Health Benefits by Bashir Ahmad, Abduh Murshed, Mohamed Y. Zaky, Imran Khan, Faiz ur Rahman, Magda H. Abdellattif, Guojun Liu, Jun Lu

“…The annual sale of medicinal plants increases over time. In plants, Berberis vulgaris f. lycium (Royle) Parsa (Berberis lycium), also called boxthoran barberry, Indian barberry, or Indian lyceum contains key alkaloids such as berberine, camptothecin, koumidine, salutaridine, luteanine, palmatine, and protopine. …”
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A Review of Reject Brine Disposal, Management, and Construction Applications by Pranita Banerjee, Essam K. Zaneldin, Ali H. Al-Marzouqi, Waleed K. Ahmed

“…The study also highlights current research gaps that are still unaddressed, hindering the complete realization of the full potential of reject brine as a sustainable resource.…”
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The Middle East Shiite Arc: A Real Threat or Geopolitical Chimera? by A. V. Sarabiev

“…The term Shiite Crescent, or Shiite Arc, is becoming increasingly popular in political and academic discourse as well as in the media. …”
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Specific features of antagonism of <i>Bacillus</i> bacteria against toxinogenic <i>Fusarium</i> fungi in protecting plants against disease and contamination with mycotoxins (review... by T. M. Sidorova, A. M. Asaturova, V. V. Allakhverdyan

“…The study contains information on the structure and mechanism of action of the main anti‐fungal cyclic lipopetides. …”
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Editor’s Note by Alberto Raposo

“…This indicates that JIS is being increasingly recognized as an interesting publication vehicle. …”
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Interactive Mode of Teaching Students in the Context of the Competence Paradigm by G. P. Sikorskaya, T. V. Savelyeva

“…The paper explores the theoretical and practical aspects of interactive mode of teaching students by using active educational methods improving the quality of educational process and increasing students’ motivation for comprehensive and in-depth learning. …”
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Sustainable Growth from a Factor Dependence and Technological Progress Perspective: A Case Study of East China by Ying Liu, Wan-Ming Chen, Sheng-Yuan Wang, Xiao-Lan Wu

“…The paper constructs an economic growth model that contains human, physical capital, innovation, and energy factors and estimates the output elasticity of seven provinces and cities in East China in the period of 2004–2018. …”
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Strengthening the Motivation of Staff as a Factor of Enterprise Competitiveness by Mahsma Mariya B.

“…The aim of the article is to study the theoretical and applied aspects of the functioning of the system of motivation of staff on the example of a production enterprise and to outline the directions of its improvement in the context of increasing the competitiveness of enterprise. The article analyzes the current state of staff motivation on the example of a leading Ukrainian company specializing in the trade of furniture components and accessories. …”
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Psycholinguistic Aspects of the Semantic Field of the Concept “War” in Modern Media Space by Yuliya Krylova-Grek

“…We underlined the link between the changes in the forms of international conflicts and the increase of the units contributing to the semantic field of the concept “war”. …”
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Deep mutagenesis scanning using whole trimeric SARS-CoV-2 spike highlights the importance of NTD-RBD interactions in determining spike phenotype. by Ruthiran Kugathasan, Ksenia Sukhova, Maya Moshe, Paul Kellam, Wendy Barclay

“…New variants of SARS-CoV-2 are continually emerging with mutations in spike associated with increased transmissibility and immune escape. Phenotypic maps can inform the prediction of concerning mutations from genomic surveillance, however most of these maps currently derive from studies using monomeric RBD, while spike is trimeric, and contains additional domains. …”
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Ghrelin stimulation of growth hormone-releasing hormone neurons is direct in the arcuate nucleus. by Guillaume Osterstock, Pauline Escobar, Violeta Mitutsova, Laurie-Anne Gouty-Colomer, Pierre Fontanaud, François Molino, Jean-Alain Fehrentz, Danielle Carmignac, Jean Martinez, Nathalie C Guerineau, Iain C A F Robinson, Patrice Mollard, Pierre-François Méry

“…Indeed, ghrelin does not modify synaptic currents of GHRH neurons. However, ghrelin exerts a strong and direct depolarizing effect on GHRH neurons, which supports their increased firing rate.…”
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Domestic Violence, Mental Health, and COVID-19: A Community-based Study of Women in Delhi by Ajit Kumar Lenka, Neha Sharawat, Smritima Diksha Lama, Sanghmitra S Acharya

“…Several factors led to an increase in the number of domestic violence cases including loss of livelihoods, restriction of social contact within informal and informal networks, and limited access to services and community support. …”
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Development and quality assessment of Coalho cheese using indigenous Pakistani milk sources: Nili-Ravi buffalo and Kamori goat by Wahab Ali Khan, Iqra Yasmin, Syed Abdul Wadood, Abbas Khan, Aiza Qamar, Maryam Hameeda, Fatima Farooq Ali, Khunsha Qamar Khan

“…Rheological measurements depicted that goat milk contributed to cohesiveness and hardness, whereas buffalo milk enhanced softness and meltability; however, storage increases the meltability and decreases cohesiveness. …”
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Kalirin-7 is a Key Player in the Formation of Excitatory Synapses in Hippocampal Neurons by Xin-Ming Ma

“…Hippocampal CA1 pyramidal neurons of Kal7 knockout (Kal7KO) mice show decreased spine density, spine length, synapse number, and postsynaptic density (PSD) size in their apical dendrites; are deficient in long-term potentiation (LTP); and exhibit decreased frequency of spontaneous excitatory postsynaptic current (sEPSC). …”
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