Enhanced Broad-Spectrum Efficacy of an L2-Based mRNA Vaccine Targeting HPV Types 6, 11, 16, 18, with Cross-Protection Against Multiple Additional High-Risk Types by Kosuke Tsukamoto, Akio Yamashita, Masatoshi Maeki, Manabu Tokeshi, Hirotatsu Imai, Akira Fukao, Toshinobu Fujiwara, Koji Okudera, Nobuhisa Mizuki, Kenji Okuda, Masaru Shimada

“…Results: We identified that a construct containing E01 (a 5′-untranslated region) and SL2.7 (a poly(A) polymerase recruitment sequence) significantly increased protein expression. …”
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Philanthrokapitalistisches Engagement in der Stadt. Memetische, hörbare und kartographische Perspektiven auf Heilbronn by K. Schmidt, I. V. Restrepo Lopez

“…This article takes the case study of Heilbronn as a starting point and analyses some urban power relations in the context of philanthrocapitalist activities in the city. …”
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Treatment Methods Dry Form of Age Macular Degeneration — History and Prospects. Review by A. N. Kulikov, M. V. Zakharov, A. A. Volozhev

“…The main treatment for wet AMD is the injection of medications called anti-VEGF agents. Currently, treatment of dry age-related macular degeneration includes modification of risk factors (stop smoking, healthy life style and etc) and dietary supplements containing a combination of certain ingredients (vitamin C, vitamin E, zinc, copper, and lutein with zeaxanthin or beta-carotene) may be able to slow the progression of the disease. …”
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Combined and progestagen-only hormonal contraceptives and breast cancer risk: A UK nested case-control study and meta-analysis. by Danielle Fitzpatrick, Kirstin Pirie, Gillian Reeves, Jane Green, Valerie Beral

“…<h4>Background</h4>Current or recent use of combined oral contraceptives (containing oestrogen+progestagen) has been associated with a small increase in breast cancer risk. …”
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Innovating through tradition: kava-talanoa as a culturally aligned medico-behavioral therapeutic approach to amelioration of PTSD symptoms by S. Apo Aporosa, Dennis Itoga, Julia Ioane, Jan Prosser, Sione Vaka, Emily Grout, Martin J. Atkins, Mitchell A. Head, Jonathan D. Baker, Tanecia Blue, David H. Sanday, Mahonri W. Owen, Chris Murray, Karthik Sivanathan, Tua’ipulotu W. Cuthers, Anau Mesui-Henry, Mary-Jane McCarthy, James Bunn, Ifereimi Waqainabete, Helen Turner, Helen Turner, Helen Turner

“…Here, we describe the development of a novel, but traditionally grounded, approach to PTSD symptomatology in the context of Pacific populations. This approach has two elements: kava is a culturally significant Pacific drink used traditionally and in cultural practice, as a relaxant, to promote dialog in group settings, to aid in sleep and to manage anxiety. …”
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Fastest Prostate Cancer Prediction on Whole-Mount Pathological Slides Using Self-Reform Multilayer Transformer by Linjie Xu, Xiaotian Yu, Haoming Luo, Jili Wang, Wenjie Liang, Jing Zhang, Zunlei Feng, Cheng Lu, Xiuming Zhang

“…Moreover, pixels in each whole-mount slide of PCa are increased by approximately <inline-formula> <tex-math notation="LaTeX">$4\sim 9$ </tex-math></inline-formula> times, therefore containing more information for diagnosis. …”
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Study of the influence of pulse heating on the structure and properties of reinforcing fibers from tungsten-rhenium alloys by V. Shalomeev, S. Sheyko, O. Hrechanyi, T. Vasilchenko, V. Vinichenko, O. Korobko

“…The component that largely determines the strength and technological properties of the composite is the fibers. Currently the requirements for the strength and technological properties of reinforcing fibers are quite fully met by wires made of various tungsten-rhenium and molybdenum-rhenium alloys. …”
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The PHD transcription factor Cti6 is involved in the fungal colonization and aflatoxin B1 biological synthesis of Aspergillus flavus by Zhang Mengjuan, Lin Guanglan, Pan Xiaohua, Song Weitao, Tan Can, Chen Xuan, Yang Yanling, Zhuang Zhenhong

“…Bioinformatics analysis showed Cti6 is conservative in Aspergillus spp., and mCherry mediated subcellular localization showed that most Cti6 accumulated in the nuclei, which reflected that Cti6 performed its important biological function in the nuclei in Aspergillus spp.. The results of the current study elucidate the roles of PHD domain containing proteins in the mechanism of the infection of crops by A. flavus, and provided a novel target for effectively controlling the contamination of Aspergillus spp. to crops.…”
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Hepatoprotective and antioxidant effects of Glycyrrhiza glabra extracts against TCDD-induced hepatocyte damage in Jian carp (Cyprinus carpio var. Jian) by Du Jinliang, Cao Liping, Jia Rui, Liu Yingjuan, Shen Yujin, Yin Guojun

“…Jian).Jian carp were fed with diet containing 3 doses of GGE (0.1, 0.5 and 1.0 g/kg diet) for 60 days before a single intraperitoneal injection of TCDD (0.6 μg/kg), 72 h after TCDD injection, blood and liver samples were taken for biochemical analysis.The results showed that GGE at 1.0 g/kg diet for 60 days prior to TCDD intoxication significantly reduced the elevated activities of ALT, AST, LDH, AKP and increased the reduced levels of total protein (TP), albumin (Alb) in the serum, markedly inhibited the reduction of the activities of superoxide dismutase (SOD), glutathione peroxidase (GPx), catalase (CAT), total antioxidant capacity (T-AOC), and reduced the malondialdehyde (MDA) formation in liver tissue. …”
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Anatomy and function of closing muscle complex of the vagina in health and pelvic organ prolapse by G. B. Dikke, A. D. Makatsariya, A. M. Ziganshin, E. A. Shaikhieva, V. O. Bitsadze

“…In modern literature, the pelvic floor muscles are presented by showing their anatomical location and indicating relevant attachment points, but their combined anatomical, topographic and functional significance is described insufficiently, which the current review was aimed at.Aim: to determine the physiological significance and anatomical units of the vagina occlusor muscle complex, topography and functions in health and in pelvic organ prolapse (POP).Materials and Methods. …”
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Antiviral Therapeutics Discovery for Enterovirus D68. by Prof Justin Jang H Chu

“…To date, there are no effective antiviral successfully developed for enterovirus infection and the current understanding on pathogenesis is limited, which has resulted in the persistent circulation and outbreaks across the globe. …”
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The Impact of Physical Activity on Retinal Health and Various Retinal Diseases by Magdalena Kwiatkowska, Gabriela Majta, Sara Kusy

“… Introduction:  The health benefits of physical activity (PA) are widely known. Currently, its role in maintaining the health of the retina and in treating various diseases of the eye is being intensively studied, which are becoming an increasingly serious public health concern. …”
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The correlation between histopathological and ultrasound findings regarding Cesarean section scars – A three-year survey study by Oana D. Bălălău, Nicolae Bacalbașa, Cristian Bălălău, Carolina Negrei, Bianca Gălățeanu, Octav Ghinghină, Cristina Răduță, Liana Pleș, Anca D. Stănescu, Vasile A. Dumitru

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The Evolution of Anatomic Pathology by Stanley Cohen, Frederick Coffman

“…Mechanism and function in biological systems can best be understood in the context of the complex microenvironments in which they occur, and for this purpose morphologic analysis can be critical. …”
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What do we know about digital public debate? Technological affordances and democratic dilemmas by Gulbrandsen Ib T., Just Sine N.

“…We illustrate the resulting six types of participation through a review of empirical studies based in the Nordic context. We summarise what we currently know about digital public debate in a key democratic dilemma: increasing digital participation goes hand in hand with decreasing institutional trust.…”
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Pesticide Residues in Fruits and Vegetables from Cape Verde: A Multi-Year Monitoring and Dietary Risk Assessment Study by Andrea Acosta-Dacal, Ricardo Díaz-Díaz, Pablo Alonso-González, María del Mar Bernal-Suárez, Eva Parga-Dans, Lluis Serra-Majem, Adriana Ortiz-Andrellucchi, Manuel Zumbado, Edson Santos, Verena Furtado, Miriam Livramento, Dalila Silva, Octavio P. Luzardo

“…Food safety concerns related to pesticide residues in fruits and vegetables have increased globally, particularly in regions where monitoring programs are scarce or inconsistent. …”
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Promising opportunities to improve polio vaccines by E. E. Evreinova, L. M. Khantimirova, V. A. Shevtsov, V. A. Merkulov, V. P. Bondarev

“…In order to meet the needs of global health, it is planned to increase the use of traditional and optimised inactivated polio vaccines and introduce new types of vaccines that are being developed based on the current understanding of RNA-containing viruses. …”
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Impact of Misting Systems on Local Particulate Matter (PM) Levels by William L. Knight, Matthew P. Fraser, Pierre Herckes

“…These experiments show PM concentrations decrease with increasing distance from misting systems. …”
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The Effect of Monetary Rewards on the Performance of Employees in an Organisation: A Case Study of Kabale District Local Government. by Nayebare, Gaston

“…Though, some of the major goals of training employees contain, increase in production, lesser labor turnover rate, higher confidence and better management and training facilitates to decrease cost as it enhances productivity, and promotes objective congruency. …”
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Cryo-EM and cryo-ET reveal the molecular architecture and host interactions of mycobacteriophage Douge by Jitendra Maharana, Chun-Hsiung Wang, Li-An Tsai, Yi-Ting Liao, Cheng-Han Yang, Melvin C. Shen, Lourriel S. Macale, Thang Ngoc Tran, Joemark Narsico, Ronelito J. Perez, Sunil Kumar Tewary, Jian-Li Wu, Hong-You Lin, Shu-Wei Chang, Aaron Franklin, Patrick J. Moynihan, Deborah Jacobs-Sera, Krista G. Freeman, Graham F. Hatfull, Todd L. Lowary, Meng-Chiao Ho

“…Molecular insights into mycobacteriophage architecture and host interactions could allow structure-guided phage engineering to increase efficacy and broaden host range, but such information is currently unavailable. …”
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