Letter to readers by Francesca Gorini

“…The evolution of educational technologies and their impact on the educational system is, also, a topic that personally involves me, having dedicated part of my research job in exploring which skills are essential to preserve and develop in order to interact appropriately with AI – a tool which is becoming increasingly pervasive even in teaching and educational contexts. …”
Get full text

Changing or validating physician opioid prescribing behaviors through audit and feedback and academic detailing interventions in primary care by Celia Laur, Natasha Kithulegoda, Nicola McCleary, Emily Nicholas Angl, Michael Strange, Barbara Sklar, Thivja Sribaskaran, Gail Dobell, Sharon Gushue, Jonathan M. C. Lam, Lindsay Bevan, Victoria Burton, Lena Salach, Justin Presseau, Laura Desveaux, Noah Ivers

“…Physicians mentioned that academic detailing validated current opioid practices or increased their belief about capabilities and their intentions , mediated by increased skills and the impact of environmental context and resources . …”
Get full text

Pharmacokinetics of levosimendan in critically Ill children on extracorporeal membrane oxygenation: a prospective observational study by Stéphane Bertin, David Haefliger, Maria-Helena Perez, Monia Guidi, Monia Guidi, Laurent A. Decosterd, Vivianne Chanez, Ermindo R. Di Paolo, Thierry Buclin, Françoise Livio

“…This suggests that dosage should be increased in this context, to achieve optimal exposure of levosimendan and its active metabolite.…”
Get full text

Investing in the future: an integrated model for analysing user attitudes towards Robo-advisory services with AI integration by Sandeep Singh, Atul Kumar

“…Filling these gaps will improve the knowledge of consumer behaviour in the context of Fintech adoption and develop the current research. …”
Get full text

The effectiveness of blended learning technologies in higher education: Assessment methodology by N. V. Bordovskaia, E. A. Koshkina, M. A. Tikhomirova, M. P. Iskhakova

“…The concept and methodology of studying the blended learning technologies effectiveness is a component of quality management concept of higher education in the context of its digital transformation and its resource-didactic provision. …”
Get full text

Polymer carrier selection for creation of diosmin solid dispersion system by hot melt extrusion by A. A. Danilova, E. V. Vishnyakov, E. S. Surbeeva, K. A. Gusev, D. N. Maimistov, E. V. Flisyuk

“…Particular importance in the context of current approach is attached to the selection of an effective polymer matrix.Aim. …”
Get full text

Management system and optimal control for three-dimensional visualization and maintenance of thermal power plant by Zhiqiang Feng, Qiuxiang Liang, Mingyi Wei, Lei Li, Youzhu Bu, Yanqing Xin

“…After optimization by CNN technology, the response time of the system is increased by 5%. The calculation cost is reduced by 15%, and the data throughput is increased by 13%. …”
Get full text

Potential of the mortgage housing lending market by N. I. Parusimova, D. A. Dobrin

“…The aim of the study is to identify causal relationships and determine the conditions for developing the potential of the mortgage housing lending market in the context of inflationary risks, a high key interest rate, and a wide range of government measures supporting access to housing for certain segments of the population. …”
Get full text

A phase II trial of mTORC1/2 inhibition in STK11 deficient non small cell lung cancer by Gary Middleton, Helen L. Robbins, Peter Fletcher, Joshua Savage, Manita Mehmi, Yvonne Summers, Alastair Greystoke, Nicola Steele, Sanjay Popat, Pooja Jain, James Spicer, Judith Cave, Paul Shaw, David Gilligan, Danielle Power, Dean Fennell, Maya Bajracharya, David J. McBride, Uma Maheswari, Alexander M. Frankell, Charles Swanton, Andrew D. Beggs, Lucinda Billingham

“…Abstract There are no current stratified medicine options for STK11-deficient NSCLC. …”
Get full text

A Concise Overview of the Use of Low-Dimensional Molybdenum Disulfide as an Electrode Material for Li-Ion Batteries and Beyond by Mattia Bartoli, Meltem Babayiğit Cinali, Özlem Duyar Coşkun, Silvia Porporato, Diego Pugliese, Erik Piatti, Francesco Geobaldo, Giuseppe A. Elia, Claudio Gerbaldi, Giuseppina Meligrana, Alessandro Piovano

“…Lithium-ion batteries (LIBs), as the cornerstone of modern portable electronics, electric vehicles, and grid-scale storage systems, are continually evolving to meet the growing performance requirements. In this dynamic context, two-dimensional (2D) materials have emerged as highly promising candidates for use in electrodes due to their layered structure, tunable electronic properties, and high theoretical capacity. …”
Get full text

A systematic review on the role of miRNAs in plant response to stresses under the changing climatic conditions by Zeqing Li, Jie Yang, Xuan Cai, Xiangling Zeng, Jing-Jing Zou, Wen Xing

“…It has concluded that the exploration of microRNAs (miRNAs) in the context of enhancing plant resilience to multiple stresses has yielded valuable insights into the intricacies of plant stress responses and the potential applications of these small regulatory molecules in agriculture for improved productivity under different stress conditions.…”
Get full text

Single-cell transcriptomics for immune profiling of cerebrospinal fluid in neurological diseases by David Ramos-Vicente, Paola Monterosso, Oriol de Fàbregues, Oriol de Fàbregues, Gerard Roch, Miquel Vila, Miquel Vila, Miquel Vila, Miquel Vila, Jordi Bové

“…This review highlights the promising advancements and addresses the current limitations of single-cell transcriptomics in the context of CSF and neurological diseases, setting the stage for future breakthroughs.…”
Get full text

Establishing priorities for future land conservation to maximise biodiversity conservation and other ecosystem services in the Tilarán Mountains of Costa Rica by Lindsay Stallcup, Matthew D. Moran, Doris Rojas, Erich Mata

“…The opportunity to connect currently protected areas to one another through effective biological corridors still remains, possibly through conservation partnerships with landowners or direct land purchase, but time could be short as increasing development and changing land-use patterns threaten to further isolate habitats in the MAB.…”
Get full text

Designing and explaining the political behavior model of managers in government organizations by Mehdi Izadi, Amir Hoshang Nazarpuri, Reza Sepahvand, Hojat Vahdati, Mohammad Hakak

“…Abstract The purpose of the current research is to design and explain the political behavior model of managers in government organizations. …”
Get full text

A second horizon scan of biogeography: Golden Ages, Midas touches, and the Red Queen by Michael N Dawson, Jan C. Axmacher, Carl Beierkuhnlein, Jessica L. Blois, Bethany A. Bradley, Anna F. Cord, Jürgen Dengler, Kate S. He, Lawrence R. Heaney, Roland Jansson, Miguel D. Mahecha, Corinne Myers, David Nogués-Bravo, Anna Papadopoulou, Björn Reu, Francisco Rodríguez-Sánchez, Manuel J. Steinbauer, Alycia Stigall, Mao-Ning Tuanmu, Daniel G. Gavin

“…., advances in genetics, remote sensing, modeling) that promote studies with increasing detail and at increasing scales; disciplinary breadth is being diversified (e.g., by developments in paleobiogeography and microbiology) and integrated through the transfer of approaches and sharing of theory (e.g., spatial modeling and phylogenetics in evolutionary–ecological contexts). …”
Get full text

Refining the link between obesity and heart failure: insights from GLP-1 receptor agonist trials and studies adopting direct adiposity measures by Nicola Riccardo Pugliese, Francesco Paneni, Domenico Tricò, Alessandra Violet Bacca, Nicolò De Biase, Hermann Dalpiaz, Alessandro Mengozzi, Agostino Virdis, Lorenzo Ghiadoni, Stefano Taddei, Reinhold Kreutz, Konstantinos Tsioufis, Stefano Masi

“…While overweight/obesity increases the risk of developing HF, its impact on patient outcomes remains complex. …”
Get full text

Young TPI: empowering animal-free science among the next- generation of scientists by Marta G. Valverde, Marta G. Valverde, Fatima Zohra Abarkan, Fatima Zohra Abarkan, Rebecca Van Eijden, Rebecca Van Eijden, Julia M. L. Menon, Julia M. L. Menon, Nikolas Gaio, Nikolas Gaio, Aarti Ramchandran, Aarti Ramchandran, Victoria C. De Leeuw, Victoria C. De Leeuw

“…In this context, Young TPI emerged as the-first-of-its-kind network comprising young professionals and students dedicated to revolutionizing scientific practices by catalyzing the shift towards animal-free research. …”
Get full text

Improvement of oilseed Brassica crops by Trichoderma use: Gene transfer and direct interaction by Tamara Sánchez-Gómez, Jorge Martín-García, Óscar Santamaría, Jorge Poveda

“…Global agriculture must urgently adopt a new approach to ensure adequate food production for the increasing population in the current context of adverse conditions, while prioritizing environmental sustainability. …”
Get full text

A mixed-methods nutrition, water, sanitation and hygiene knowledge, attitudes, and practices survey of IDPs, returnees, and host community members in four counties of Jonglei state... by Lynn Lieberman Lawry, Rachel Gabor, Jacques Katele, Lazarus Baak Madut, Katina Sommers, David Manuel, Claire Nadolski, Mounir Lado, Tracey Perez Koehlmoos, William Clemmer

“…Improved flood resistant sources for clean water, clean covered water storage container distribution, improved sanitation, oral rehydration solution (ORS) and zinc distribution and education are necessary to decrease diarrheal rates.…”
Get full text

Digital currency: features of regulation in the Russian Federation by T. E. Rozhdestvenskaya, A. G. Guznov

“…The article examines the main approaches to the regulation of digital currencies, studies the phenomenon of digital currency itself, assesses the circumstances that aroused massive interest and enthusiasm for cryptocurrencies. An analysis of current positive legal material is presented, in particular, the approach to the regulation of digital currency contained in the Russian Federal Law of July 31, 2020 No. 259- FZ "On digital financial assets, digital currency and on amendments to certain legislative acts of the Russian Federation". …”
Get full text