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4081
Differences between the European and Eurasian Good Pharmacovigilance Practices
Published 2021-07-01“…However, the number of differences between the documents increases, as changes are made to the EU GVP. A more comprehensive harmonisation of the EAEU GVP with the current version of the EU GVP will make it possible to develop and use uniform pharmacovigilance documents in the EU and EAEU, and will facilitate the introduction of EAEU medicines into the global pharmaceutical market.…”
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4082
Surface modification of aluminum on a silicon chip by citric acid treatment
Published 2025-08-01“…In situ electrical current measurements from arrays of aluminum wires located on the silicon chip were performed during the treatment. …”
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4083
Broadband Chirped InAs Quantum-Dot Superluminescent Light-Emitting Diodes With In<sub>x</sub>Al<sub>1-x</sub>As Strain-Reducing Layers
Published 2016-01-01“…In the SLED devices, a broad and uniform spectrum with a linewidth of 100 nm at 3 dB is realized at an injection current level of 100 mA, and no significant spectrum dip is observed in the entire injection current window ranging from 50 <inline-formula> <tex-math notation="LaTeX">$\mu\text{A}$</tex-math></inline-formula> to 100 mA.…”
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4084
Adenosine A2A receptor agonist polydeoxyribonucleotide ameliorates short-term memory impairment by suppressing cerebral ischemia-induced inflammation via MAPK pathway.
Published 2021-01-01“…In order to confirm the participation of the adenosine A2A receptor in the effects mediated by PDRN, 8 mg/kg 7-dimethyl-1-propargylxanthine (DMPX), adenosine A2A receptor antagonist, was treated with PDRN. In the current study, induction of ischemia enhanced the levels of pro-inflammatory cytokines and increased phosphorylation of MAPK signaling factors in the hippocampus and basolateral amygdala. …”
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4085
Prospective Interventions for reducing the vulnerability of communities in post-disaster resettlement, a case of Bunambutye camp, Eastern Uganda
Published 2024-08-01“…We recommend the establishment of a skills-based training institution within the resettlement that should train survivors using content customized to address current and future needs hence ensuring self-sufficiency, reliance, and livelihood sustainability through outcomes like increased disposable incomes and wellbeing of the survivors in the resettlement. …”
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4086
Microbiological examination of aerosols and sprays
Published 2023-09-01“…The current regulatory standards for microbiological testing of medicines provide little information on the quality control of metereddose aerosols. …”
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4087
The Involvement of Ser1898 of the Human L-Type Calcium Channel in Evoked Secretion
Published 2011-01-01“…This mutation does not alter basal CaV1.2 current properties or regulation of CaV1.2 current by PKA and the beta-adrenergic receptor, but abolishes CaV1.2 phosphorylation by PKA. …”
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4088
Productivity and nutritional value of aboveground biomass of annual crops in companion sowings
Published 2021-07-01“…Siberian and Italian millet formed mean productivity of 16.13 and 15.60 t/ha, respectively. The current paper has presented data on productivity and has studied feed advantages of single-species and two-species sowings. …”
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4089
Insect farming: A bioeconomy-based opportunity to revalorize plastic wastes
Published 2025-01-01“…Managing plastic waste is one of the greatest challenges humanity faces in the coming years. Current strategies—landfilling, incineration, and recycling—remain insufficient or pose significant environmental concerns, failing to address the growing volume of plastic residues discharged into the environment. …”
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4090
Mesenchymal stem cell- derived exosomes as cell-free therapeutics for sensorineural hearing loss
Published 2025-03-01“…This paper aims to review current knowledge on the use of MSCs and MSC-derived exosomes for inner ear sensory cell regeneration and explore their potential for clinical applications. …”
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4091
Study on the Preparation and Corrosion Properties of Hydrotalcite Composite Permeation Layer via Plasma Electrolytic Carbonitriding
Published 2024-11-01“…In order to improve the corrosion resistance of steel materials treated by plasma electrolytic infiltration,annealed 20 steel was used as the experimental substrate.Micro-nanopores formed during the plasma electrolytic carbonitriding process were utilized as containers to load magnesium-iron layered double hydroxides (Mg-Fe-LDHs) as a corrosion inhibitor,and the effects of Mg-Fe-LDHs on the corrosion performance of 20 steel were investigated.First,formamide was used as the carbon and nitrogen source,and KCl was used as the conductive salt.These components were mixed with deionized water to form an electrolyte.Then,the samples were treated at a constant DC pulse voltage of 220 V for 9 min to produce a carbonitrided layer (denoted as PEC/N samples).Subsequently,the PEC/N samples were immersed in a Mg-Fe-LDHs precursor solution containing urea,MgSO4 and Na2CO3,and hydrothermally crystallized at 140 ℃for 10 h to obtain a composite infiltration layer (denoted as PEC/N-LDHs samples).The performance of the composite infiltration layers was analyzed using a microhardness tester,scanning electron microscopy (SEM),X-ray diffraction (XRD) and electrochemical testing.Results showed that the microhardness of the composite infiltration layer reached approximately 900 HV,which was 4.6 times higher than that of the substrate.The carbonitrided layer of the PEC/N samples was about 20 μm,with a smooth and flat cross-section but a rough,porous and honeycomb-like surface.After hydrothermal synthesis of LDHs,the surface became smooth,lacking a visible honeycomb structure,and a large number of flake-like crystalline deposits appeared on the surface.The XRD spectra of the PEC/N samples showed absorption peaks corresponding to Fe3C,Fe5C2,α-Fe and Fe3N phases.After the in-situ loading of Mg-Fe-LDHs,new absorption peaks corresponding to the (003),(006) and (009) crystal planes of Mg-Fe-LDHs appeared in the XRD spectra of the PEC/N-LDHs samples.Combined with SEM morphology analysis,it was confirmed that Mg-Fe-LDHs were successfully loaded,presenting a flake-like structure.Compared with 20 steel,the PEC/N samples exhibited improved corrosion potential (Ecorr) and corrosion current density (Jcorr),reaching-0.451 V and 75.22 μA/cm2,respectively,although the lowfrequency impedance modulus (|Z |0.01 Hz) showed no significant increase,reaching only 998.5 Ω·cm2.After loading Mg-Fe-LDHs,the PEC/N-LDHs samples demonstrated further improvements,with Ecorr,Jcorr and |Z |0.01 Hz reaching-0.355 V,39.11 μA/cm2 and 6 586.0 Ω·cm2,respectively,showing significant enhancement compared to both 20 steel and PEC/N samples.These results indicated that plasma electrolytic carbonitriding treatment of 20 steel could produce a carbonitrided layer with high hardness.Additionally,the hydrothermal loading of LDHs further improved the corrosion resistance of the composite infiltration layer without affecting its hardness.The PEC/N-LDHs composite infiltration layer thus achieved both high hardness and superior corrosion resistance.…”
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4092
Pre-sleep casein ingestion with probiotic strains improves anaerobic power and lower-body-specific strength and power performance in soccer players
Published 2025-12-01“…One-way analysis of covariance (ANCOVA) or Quade tests with a significance level of p < 0.05 was used to analyze the collected data.Result The current study’s findings indicated that APT-180°/s (ext) significantly increased in CAS (p = 0.008) and PRO+CAS (p = 0.003) compared to PLA. …”
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4093
Progress of arylacetamide deacetylase research in metabolic diseases
Published 2025-05-01“…It plays a significant role in drug metabolism, lipid metabolism, and the pathogenesis of various diseases. In the context of drug metabolism, AADAC is vital for ensuring the safety of ester-based drugs. …”
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4094
Wear-resistant Ti/TiCp composite coatings via synchronous powder supplied wire arc additive manufacturing
Published 2025-01-01“…As the current increases, the number of in-situ primary TiC grains in the matrix increases, and many coarse dendritic structures can be observed. …”
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4095
Tuning biodegradable Mg–4Sn alloy with Ag addition and heat treatment: Unveiling microstructural, mechanical, and corrosive behaviors
Published 2025-06-01“…The ultimate shear strength and corrosion current density of the as-cast Mg–4Sn alloy increased from 89 MPa and 4.33 µA/cm2 to 103 MPa and 4.58 µA/cm2, respectively, with the addition of 0.2 % Ag. …”
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4096
Unveiling polyoxometalate redox properties at the nanoscale
Published 2024-11-01“…They hold promise as charge storage nodes in multilevel nonvolatile memories and resistive switching devices, areas of interest currently boosted by the development of neuromorphic computing. …”
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4097
Effects of Microstructured and Anti-Inflammatory-Coated Cochlear Implant Electrodes on Fibrous Tissue Growth and Neuronal Survival
Published 2025-01-01“…However, due to the trauma caused by the insertion of the electrode and the subsequent formation of connective tissue, their clinical effectiveness varies. The aim of the current study was to achieve a long-term reduction in connective tissue growth and impedance by combining surface patterns on the electrode array with a poly-L-lactide coating containing 20% diclofenac. …”
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4098
Brain endurance training as a strategy for reducing mental fatigue
Published 2025-06-01“…While BET consistently improves endurance performance, its effects on subjective mental fatigue are currently less conclusive, which offers intriguing possibilities for future research. …”
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4099
Development of Lentil Aquafaba-Based Food Emulsions with Xanthan Gum or Pregelatinized Corn Starch as Stabilizers
Published 2025-01-01“…Currently, there is an increasing trend towards the use of legumes aquafaba-based emulsions for food applications. …”
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4100
The Effect of Monetary Rewards on the Performance of Employees in an Organisation: A Case Study of Kabale District Local Government.
Published 2023“…Though, some of the major goals of training employees contain, increase in production, lesser labor turnover rate, higher confidence and better management and training facilitates to decrease cost as it enhances productivity, and promotes objective congruency. …”
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