Immunological and physiological changes of exercise-released lactate on tumors: an important and new research window by Amir Hossein Ahmadi Hekmatikar, Arsham Entesari, Hossein Shirvani

“…In the cancer immune cycle, the immune checkpoint PD-1 and its ligand PD-L1 collaborate to facilitate immune escape and promote tumor progression (Keir et al., 2008). In this context, a study revealed that lactate can enhance the expression of PD-L1 on tumor cells, suggesting that lactate may have a protective effect against tumors by increasing PD-L1 expression (Feng et al., 2017). …”
Get full text

Ozonolytic synthesis of 2-hydroxybenzyl alcohol for the production of gastrodin by A. H. Halstian, A. S. Hasanova, H. V. Tarasenko

“…Continuous monitoring of the current concentration of ozone, with the recording of the analysis results in the form of a kinetic curve, was carried out when ozone-containing gas passed through the curette at a certain wavelength of a monochromatic light source. …”
Get full text

The impact of electronic cigarette smoking on periodontal status and proinflammatory cytokine levels: a cross-sectional study by Banna Alnufaiy, Hanadi Ghurmallah Alzahrani, Rhodanne A. Lambarte, Mohannad Abdullah Alghamdi, Abdulelah Saad Alali, Wael Farhan Alanazi, Mohammad Hamad Alkanhal, Abdulrahman Farhan Almukhalfi

“…Abstract Background E-cigs(E-cigs) use is increasing worldwide. Recent studies suggest that E-cigs contain harmful elements that could lead to adverse oral health outcomes. …”
Get full text

Improved Mechanical Performances of Hastelloy C276 Composite Coatings Reinforced with SiC by Laser Cladding by Yuqing Tang, Zheng Lu, Xuan Zhang, Xihuai Wang, Shengbin Zhao, Mingdi Wang

“…The self-corrosion potential measured at 315 mV, with a self-corrosion current density of 6.884 × 10⁻⁶ A/cm², and the electrochemical charge-transfer resistance was approximately 25 times that of the substrate and 1.26 times that of the 0 wt%. …”
Get full text

Construction of Modified Mesoporous Graphite Phase Carbon Nitride Material and Its Photocatalytic U(Ⅵ) Reduction Performance by YU Mingyue1, HAO Shuai1, HUANG Wenlong1, JIANG Dongmei2, XIA Liangshu1

“…Consequently, the uranium-containing wastewater produced poses significant and substantial threats to environmental safety and public health. …”
Get full text

Integrating quantum synchronization in future generation networks by Swaraj Shekhar Nande, Muhammad Idham Habibie, Milad Ghadimi, Andrea Garbugli, Koteswararao Kondepu, Riccardo Bassoli, Frank H. P. Fitzek

“…However, existing standards, such as the precision time protocol, are unreliable due to jitters, datagram losses, and complexity. Increasing the synchronization error from the ideal tens of nanoseconds to hundreds of microseconds is unacceptable in future-generation networks. …”
Get full text

Presentation of Financial Assets in Russian Macroeconomic Statistics by V. N. Salin, M. V. Vakhrameeva, O. Yu. Sitnikova

“…The purpose of the study. Currently, much attention is paid to the collection, presentation and analysis of data on the volume, structure and dynamics of economic assets. …”
Get full text

Materials and Structures Used in Aeronautics: Present and Future Perspectives by Mihai FLOREA, Vlad-Stefan CONSTANTIN, Andrei-Christian BUCUR, Raluca FAUR, Denis PREDU, Alexandru CAZACU

“…Trial and error can be costly in this context, necessitating well-planned design and engineering to ensure resistance to aerodynamic forces during flight. …”
Get full text

Linking weather and climate information services (WCIS) to Climate-Smart Agriculture (CSA) practices by Tafadzwanashe Mabhaudhi, Tinashe Lindel Dirwai, Cuthbert Taguta, Aidan Senzanje, Wuletawu Abera, Ajit Govid, Elliott Ronald Dossou-Yovo, Ermias Aynekulu, Vimbayi Grace Petrova Chimonyo

“…Specifically, it addresses the following questions: (1) What is the current status of knowledge on WCIS and CSA in the global south, specifically the African continent?…”
Get full text

Tracking development assistance for health from China, 2007–2017 by Angela E Micah, Catherine S Chen, Abigail Chapin, Joseph L Dieleman, Paul H Lee, Michael R Phillips, Kun Tang, Shenglan Tang, Jost Jonas, Shiwei Liu, Yingxi Zhao, Bianca S. Zlavog, Golsum Tsakalos, Stephen Gloyd, Man Tat Alexander Ng, Enrico Rubagotti, Mustafa Younis, Yunquan Zhang

“…However, relative to population size and government spending, China’s contributions are modest.Conclusion In the current context of plateauing in the growth rate of DAH contributions, China has the potential to contribute to future global health financing, especially financing for health system strengthening.…”
Get full text

Investigating The Possibility of Extracting Phenolic Compounds from Raisin Waste with The Aim of Waste Management from Raisin Processing Units by Amir Abbas Matin, Bahar Azimi, Hosein Hashempoor

“…Introduction: Grapes are one of the most important and most productive agricultural harvests in the world. Iran is currently the seventh largest producer of grapes in the world, with over 252,000 hectares of vineyards. …”
Get full text

Why a strong global plastics treaty is essential for agricultural systems, food safety, food security and human health by Marie-France Dignac, Melissa Bakhos, Susanne Brander, Gabin Colombini, Megan Deeney, Etienne Dufour, Violette Geissen, Asta Hooge, Esperanza Huerta Lwanga, Baptiste Monsaingeon, Kristian Syberg, Joe Yates

“…An ambitious global plastics treaty is urgently needed to decrease soil pollution from microplastics and nanoplastics (MNPs), originating both from intentional uses of agricultural plastics and from composts and sludges applied to soils, contaminated due to the increasing plastic production and use. The current narrative, biased by vested interests, overemphasizes short-term benefits of agricultural plastics, while ignoring their adverse effects. …”
Get full text

Epidemiological Situation on Cholera in the Russian Federation in 2023 and Forecast for 2024 by A. Yu. Popova, A. K. Noskov, E. B. Ezhlova, V. D. Kruglikov, E. V. Monakhova, O. S. Chemisova, A. A. Lopatin, S. M. Ivanova, O. A. Podoynitsyna, A. S. Vodop’yanov, D. A. Levchenko, I. V. Savina

“…It was established that the toxigenic strains isolated from patients belonged to the currently dominant in the world “post-Haitian” group, including in India and Bangladesh, with the genotype ctxB7 tcpACIRS rtxA4a VSP-IIΔ0495-0512. …”
Get full text

Digital augmentation of aftercare for patients with anorexia nervosa: the TRIANGLE RCT and economic evaluation by Janet Treasure, Katie Rowlands, Valentina Cardi, Suman Ambwani, David McDaid, Jodie Lord, Danielle Clark Bryan, Pamela Macdonald, Eva Bonin, Ulrike Schmidt, Jon Arcelus, Amy Harrison, Sabine Landau

“…Support for the diversity of carers of eating disorders (fathers, partners, siblings) in different cultural contexts across the spectrum of eating disorders The current model of carers support is designed for parents (particularly mothers) of white, highly educated patients with AN. …”
Get full text

Life or limb: an international qualitative study on decision making in sarcoma surgery during the COVID-19 pandemic by Peter F M Choong, Michelle M Dowsey, Samantha Bunzli, Michelle Ghert, Ajay Puri, Robert Turcotte, Penny O'Brien, Peter Rose, Will Aston, Miguel A Ayerza, Lester Chan, Stephane Cherix, Jorge de las Heras, Davide Donati, Uwale Eyesan, Nicola Fabbri, Thomas Hilton, Oluwaseyi Kayode Idowu, Jungo Imanishi, Dundar Sabah, Kristy Weber

“…Common to ‘unique’ decisions about patient care was uncertainty about what was going on and what would happen in the future (theme 1: the context of uncertainty), the impact of the pandemic on resources or threat of the pandemic to overwhelm resources (theme 2: limited resources), perceived increased risk to self (theme 3: duty of care) and least-worst decision making, in which none of the options were perceived as ideal and participants settled on the least-worst option at that point in time (theme 4: least-worst decision making).Conclusions In the context of rapidly changing standards of justice and beneficence in patient care, traditional decision-making frameworks may no longer apply. …”
Get full text

Vaccination as a Promising Approach in Cardiovascular Risk Mitigation: Are We Ready to Embrace a Vaccine Strategy? by Georgios Tsioulos, Natalia G. Vallianou, Alexandros Skourtis, Maria Dalamaga, Evangelia Kotsi, Sofia Kargioti, Nikolaos Adamidis, Irene Karampela, Iordanis Mourouzis, Dimitris Kounatidis

“…Consequently, immunomodulatory strategies have gained increasing attention, though none have yet reached widespread clinical adoption. …”
Get full text

The methyl-CpG binding domain 2 regulates peptidylarginine deiminase 4 expression and promotes neutrophil extracellular trap formation via the Janus kinase 2 signaling pathway in e... by Biao Peng, Mu-Yun Yan, Yun-Rong Chen, Fei Sun, Xu-Dong Xiang, Da Liu

“…Objective The prognosis for severe asthma is poor, and the current treatment options are limited. The methyl-CpG binding domain protein 2 (MBD2) participates in neutrophil-mediated severe asthma through epigenetic regulation. …”
Get full text

Potential therapeutic effects of IL28RA inhibition on acute myocardial infarction through phosphorylated JAK1/STAT1 signaling pathways by Ge Gong, Xiangxuan Chen, Xinghu Zhang, Jian Yin, Wenhui Wan

“…Abstract While current coronary intervention therapies and surgical bypass procedures are widely utilized, the treatment of acute myocardial infarction (AMI) in the elderly continues to pose significant challenges. …”
Get full text

Reporting quality of systematic review protocols in environmental and occupational toxicology: a meta-epidemiology study protocol by Milica D. Pavlovic, Malgorzata Lagisz, Natália B. Videira, Julia M. L. Menon, Gunn E. Vist, Elma Omeragic, Rebecca L. Morgan, Sebastian Hoffmann, Evidence-Based Toxicology Collaboration

“…Background Systematic reviews (SR), an evidence-synthesis tool, have been increasingly used in toxicology, for regulatory decision-making and allocation of research funding resources. …”
Get full text

Characteristics, outcomes, and maternity care experiences of women with children’s social care involvement who subsequently died: national cohort study and confidential enquiry by Marian Knight, Abigail Easter, Jane Sandall, Elsa Montgomery, Nicola Vousden, Emma Rose, Claire Mason, Kirsty Kitchen, Kaat De Backer, Allison Marjorie Felker, Caroline Bull, Oluwaseun Labisi

“…A critical review of current care pathways and policy changes is urgently needed to tailor care to the needs of this group of women and to look at the inequalities that disproportionately affect them.…”
Get full text