On the added value of sequential deep learning for the upscaling of evapotranspiration by B. Kraft, B. Kraft, B. Kraft, J. A. Nelson, S. Walther, F. Gans, U. Weber, G. Duveiller, M. Reichstein, W. Zhang, M. Rußwurm, D. Tuia, M. Körner, Z. Hamdi, M. Jung

“…However, together with the non-temporal FCN model, they exhibited a larger ensemble spread than XGBoost, and they yielded lower global ET estimates than what is currently understood. XGBoost showed a smaller ensemble spread compared to neural networks, in particular when conditions were poorly represented in the training data, but it was more sensitive to the covariate setup. …”
Get full text

Design and Synthesis of Bis-Chalcones as Curcumin Simplified Analogs and Assessment of Their Antiproliferative Activities Against Human Lung Cancer Cells and <i>Trypanosoma cruzi</... by Gabriela Alves de Souza, Lorrane de Souza Chaves, Afonso Santine M. M. Velez, Jorge Lucas F. Lacerda, Paulo Pitasse-Santos, Jayane Clys Conceição dos Santos, Otávio Augusto Chaves, Carlos Serpa, Raphael do Carmo Valente, Leonardo Marques da Fonseca, Marcos André Rodrigues da Costa Santos, Jhenifer Santos dos Reis, Carlos Antônio do Nascimento Santos, Lucia Mendonça-Previato, Jose Osvaldo Previato, Celio Geraldo Freire-de-Lima, Debora Decoté-Ricardo, Leonardo Freire-de-Lima, Marco Edilson Freire de Lima

“…<b>Background: </b>Anticancer therapies represent the primary treatment option for a significant number of cancer patients globally; however, many of these treatments are associated with severe side effects as they target molecular structures present in both cancerous and healthy cells. In a similar context, the treatment of Chagas disease, a neglected tropical illness, is hindered by the high toxicity of the currently available drugs. …”
Get full text

Contextual Vulnerability Should Guide Fair Subject Selection in Xenotransplantation Clinical Trials by Gianna Strand

“…This paper describes the current transplant system’s use of subjective evaluation criteria, particularly psychosocial support and compliance. …”
Get full text

Social Networks Link Prediction Based on Incremental Learning by Jian SHU, Zhichen CHEN

“…However, the prediction performance of IL−SNLP on Ask Ubuntu and Super User decreases by only 4.54% and 5.25%, respectively, compared to its performance on Math Overflow. …”
Get full text

Emotional literacy programme in special schools for children with a learning disability in England: the ZF-SEND feasibility RCT by Biza Stenfert Kroese, Gemma Unwin, Richard Hastings, Andrew Jahoda, Rachel McNamara, David Gillespie, Jeremy Segrott, Kate Ingarfield, Myrsini Gianatsi, Elizabeth Randell, Zoe Mather, Barbara Barrett, Poushali Ganguli, John Rose, Mariam Sahle, Emily Warren, Nathan Da Cruz

“…Future work On the basis of the current findings, an application for a full trial will be prepared and submitted with a number of amendments. …”
Get full text

Key Drivers Affecting the Future of Power Relations in Tehran Metropolis with a Scenario-Writing Approach by Afshin Mottaghi, Arash Ghorbani Sepehr, Joseph Saloukadz

“…Given this context, the central question guiding the present research was this: What are the drivers and future scenarios of power relations in Tehran Metropolis? …”
Get full text

Regulatory culture and architectural project by Mario Losasso

“…They are attentive to a quality that does not depend on construction solutions or on techno-typological, morphological or physical-chemical characteristics, but which is linked to a system of needs to be satisfied, the outcome of the interaction between construction and cultural, socio-economic and environmental context. Today’s regulatory landscape has expanded, increasing sensitivities to environmental challenges, health and the qualities of living space. …”
Get full text

A Legal Analysis of Liability for the Loss of the Subject Matter of Sale after Contract Termination: A New Inquiry into Sunni Jurisprudence by Mohammad Hossein Taghipour Darzi Naghibi, Umm al-Banin Ramzan Zadeh, Mostafa Firoozi Rad

“…Determining who bears the liability for this loss becomes a contentious issue: should it be the party currently in possession or the rightful owner awaiting the return? …”
Get full text

Improving older people’s experiences and safety at transitions of care: the PACT mixed-methods study including RCT by Jenni Murray, Ruth Baxter, Jane O’Hara, Laura Sheard, Catherine Hewitt, Natasha Hardicre, Charles Vincent, Eirini Oikonomou, Gerry Richardson, Rosie Shannon, Kalpita Baird, Stephen Brealey, Robbie Foy, Laura Mandefield, Sarah Hampton, Ed Breckin, Lubena Mirza, Alfredo Palacios, Sally Moore, Jayne Marran, Jacqui Elliot, Jane Schofield, Alison Cracknell, Beth Woods, Sarah Cockayne, Thomas Mills, Yvonne Birks, Olivia Joseph, Rebecca Lawton

“…This research aimed to understand if increased involvement of older people in their care in hospital would improve the safety and experience of care transitions. …”
Get full text

A novel in vitro system for simultaneous infections with hepatitis B, C, D and E viruses by Roxanne Fouillé, Eloi R. Verrier, Amse De Meyer, Lieven Verhoye, Maud Michelet, Romain Barnault, Caroline Pons, Olivier Diaz, Michel Rivoire, Guillaume Passot, Eike Steinmann, Heiner Wedemeyer, Anna Salvetti, Nicole Pavio, Virginie Doceul, Raphaël Darteil, Philip Meuleman, David Durantel, Julie Lucifora

“…Using HEV-infected HuHep mice, we confirmed the antiviral effect of vonafexor, an FXR agonist, that is currently being tested clinically against HBV/HDV. …”
Get full text

Conceptualization of Policies, Strategies and Programs for Poverty Alleviation in Iran: A Qualitative Study by Hassan Danaeefard, Morteza Nabavi, Faramarz Nasri, Seyed Mohammad Javad Sajjadi Nezhad

“…., were created to help alleviate poverty in the country.The Research Center of the Islamic Council has stated in a report that the poverty line rate has been increasing since 2011 and has reached from 19.4% to 30/4% in 2021. …”
Get full text

Multi-omics reveals total flavones from Abelmoschus manihot (L.) Medik. [Malvaceae] ameliorate MAFLD via PI3K/AKT/mTOR-mediated autophagy by Chao Lv, Chao Lv, Chao Lv, Chao Lv, Chao Lv, Lei Zhao, Jiani Hou, Hongyin Sun, Hongyin Sun, Hongyin Sun, Zhongsha Li, Zhongsha Li, Zhongsha Li, Zhongsha Li, Yuesong Wu, Yuesong Wu, Yuesong Wu, Yuesong Wu, Peizheng Shi, Yaping Xiao, Yunjin Xie, Yunjin Xie, Yunjin Xie, Yunjin Xie, Wei Su, Wei Su, Wei Su, Wei Su, Mingzhu Yin, Mingzhu Yin, Mingzhu Yin, Mingzhu Yin

“…(Malvaceae), abbreviated as TFA, in the context of MAFLD. Ultra-high-performance liquid chromatography-quadrupole orbitrap mass spectrometry (UHPLC-QTOF-MS) was used to identify the metabolites in TFA. …”
Get full text

Anisotropic flexible stress sensors based on Loofah/CN/MWCNTs by 刘璐, 贾晓丽, 黄书童, 张景龙, 李守宝, 柯燎亮

“…Consequently, the loofah skeleton and conductive coating were compressed and released simultaneously, effectively functioning as a variable resistor. As applied stress increased, the loofah framework became more compact, gradually increasing the contact area between carbon-based materials of different sizes, thereby generating new current pathways. …”
Get full text

Balancing Innovation and Ethics by Anisa Patel

“…Even DNA testing company 23andMe states, “Currently 23andMe has several features that can reveal genetic evidence of Indigenous American ancestry, although they are not considered a confirmatory test or proof of such ancestry in a legal context.”[7]  These companies cannot fully confirm the accuracy of their tests in finding ancestral information and therefore should not be completely relied upon for discovering self-identity. …”
Get full text

Balancing Innovation and Ethics by Anisa Patel

“…Even DNA testing company 23andMe states, “Currently 23andMe has several features that can reveal genetic evidence of Indigenous American ancestry, although they are not considered a confirmatory test or proof of such ancestry in a legal context.”[7]  These companies cannot fully confirm the accuracy of their tests in finding ancestral information and therefore should not be completely relied upon for discovering self-identity. …”
Get full text

Studying the Requirement of Water Police to Control Groundwater Resources in the Villages Iij, Jovin and Soufiabad of Sorkheh - Semnan by Peyman Akbarzadeh, Mohammadreza Yazdani, Shima Nikoo

“…The pattern of water consumption is currently undergoing drastic changes (10 years ago). …”
Get full text

Effects of Conditioning Temperature on Pellet Quality, Nutrients Digestibility, and Metabolizable Energy of Broilers Diet by Seyedeh Vajiheh Shakhese Emampour, Abolghasem Golian, Heydar Zarghi, Ali Reza Hesabi Nameghi

“…So that the amount of electricity usage decreased (quadratic, p< 0.001), and increased pellet PDI (quadratic, p<0.001) and pellet hardness (linear, p<0.002) by increasing in conditioning temperature. …”
Get full text

Time to treat the climate and nature crisis as one indivisible global health emergency by Kamran Abbasi, Parveen Ali, Virginia Barbour, Thomas Benfield, Kirsten Bibbins-Domingo, Stephen Hancocks, Richard Horton, Laurie Laybourn-Langton, Robert Mash, Peush Sahni, Wadeia Mohammad Sharief, Paul Yonga, Chris Zielinski

“…Fish provide more than half of dietary protein in many African, South Asian and small island nations, but ocean acidification has reduced the quality and quantity of seafood.16 Changes in land use have forced tens of thousands of species into closer contact, increasing the exchange of pathogens and the emergence of new diseases and pandemics.17 People losing contact with the natural environment and the declining loss in biodiversity have both been linked to increases in non-communicable, autoimmune, and inflammatory diseases and metabolic, allergic and neuropsychiatric disorders.10,18  For Indigenous people, caring for and connecting with nature is especially important for their health.19 Nature has also been an important source of medicines, and thus reduced diversity also constrains the discovery of new medicines. …”
Get full text

Group-based interventions to reduce gambling involvement among male football fans: a synopsis of findings from a feasibility study by Gerda Reith, Blair Biggar, Chris Bunn, Manuela Deidda, Craig Donnachie, Frankie Graham, Cindy Gray, Nicola Greenlaw, Kate Hunt, Matthew Philpott, Neil Platt, Robert D Rogers, John Rooksby, Sally Wyke, Heather Wardle

“…Football Fans and Betting was most successful in feasibility delivery when it was delivered within grassroots and local community contexts. Conclusions In the current climate of gambling industry penetration into professional football, promoting a gambling harms prevention intervention proved an insurmountable challenge. …”
Get full text

Digital augmentation of aftercare for patients with anorexia nervosa: the TRIANGLE RCT and economic evaluation by Janet Treasure, Katie Rowlands, Valentina Cardi, Suman Ambwani, David McDaid, Jodie Lord, Danielle Clark Bryan, Pamela Macdonald, Eva Bonin, Ulrike Schmidt, Jon Arcelus, Amy Harrison, Sabine Landau

“…Support for the diversity of carers of eating disorders (fathers, partners, siblings) in different cultural contexts across the spectrum of eating disorders The current model of carers support is designed for parents (particularly mothers) of white, highly educated patients with AN. …”
Get full text