Prevalence of viral DNA in high-grade serous epithelial ovarian cancer and correlation with clinical outcomes. by Sharon E Robertson, Maya Yasukawa, Douglas C Marchion, Yin Xiong, Syeda Mahrukh Hussnain Naqvi, Tarik Gheit, Massimo Tommasino, Robert M Wenham, Anna R Giuliano, Johnathan M Lancaster, Mian M K Shahzad

“…<h4>Introduction</h4>Currently 11 infectious agents are classified as carcinogenic but the role of infectious agents on outcomes of epithelial ovarian cancer is largely unknown.…”
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A second horizon scan of biogeography: Golden Ages, Midas touches, and the Red Queen by Michael N Dawson, Jan C. Axmacher, Carl Beierkuhnlein, Jessica L. Blois, Bethany A. Bradley, Anna F. Cord, Jürgen Dengler, Kate S. He, Lawrence R. Heaney, Roland Jansson, Miguel D. Mahecha, Corinne Myers, David Nogués-Bravo, Anna Papadopoulou, Björn Reu, Francisco Rodríguez-Sánchez, Manuel J. Steinbauer, Alycia Stigall, Mao-Ning Tuanmu, Daniel G. Gavin

“…., advances in genetics, remote sensing, modeling) that promote studies with increasing detail and at increasing scales; disciplinary breadth is being diversified (e.g., by developments in paleobiogeography and microbiology) and integrated through the transfer of approaches and sharing of theory (e.g., spatial modeling and phylogenetics in evolutionary–ecological contexts). …”
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Letter to readers by Francesca Gorini

“…The evolution of educational technologies and their impact on the educational system is, also, a topic that personally involves me, having dedicated part of my research job in exploring which skills are essential to preserve and develop in order to interact appropriately with AI – a tool which is becoming increasingly pervasive even in teaching and educational contexts. …”
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Fabrication of biodegradable silicon nitride 3D printed nanocomposite with enhanced mechanical and antimicrobial properties for bone tissue repair by Femi B. Alakija, David K. Mills

“…The porosity test showed that the addition of Si3N4 does not affect the porosity or cell attachment of the fabricated nanocomposites, while histological staining revealed increased calcium and mucopolysaccharides. The nanocomposite exhibited excellent mechanical properties, including higher flexural strength, hardness, and a lower contact angle after surface coating with protein. …”
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Analysis of Damage Characteristics and Fragmentation Simulation of Soybean Seeds Based on the Finite-Element Method by Yuxuan Chen, Zhong Tang, Bin Li, Shiguo Wang, Yang Liu, Weiwei Zhou, Jianpeng Jing, Xiaoying He

“…The experimental results indicate that as the contact area decreases, the crushing load increases, with soybeans in the horizontal orientation being able to withstand the highest ultimate pressure. …”
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Amyloidogenic immunoglobulin light chains disturb contractile function and calcium transients in a human cardiac spheroid model of light chain (AL) amyloidosis by Mélanie Bézard, Jean-Sébastien Vartanian-Grimaldi, Julien Henri, Denisa Calin, Amira Zaroui, Mounira Kharoubi, Thibaud Damy, Onnik Agbulut, Ekaterini Kordeli

“…LC-treated hiPSC-CM cultures and LC-containing spheroids presented structural and functional defects including: (1) decreased levels and subcellular disorganization of sarcomeric protein alpha-actinin; (2) abnormal accumulation of calcium handling SERCA2a protein; (3) impaired contractility of spheroids and altered calcium transients. …”
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Evaluating Dietary Red Lentil Screenings on Performance, Antioxidant Status, Caecal Environment, and Intestinal Morphometric Features in Rabbits by Gianluca Pugliese, Caterina Losacco, Letizia Passantino, Giovanni Lentini, Maria M. Cavalluzzi, Michele Schiavitto, Simona Tarricone, Vito Laudadio, Vincenzo Tufarelli

“…Dietary RLS significantly decreased serum total cholesterol, LDL, and HDL, along with an enhancement of the overall serum antioxidant capacity. …”
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Identification, Evolution and Expression Analyses of the Hox Family in Procambarus clarkii by Xiaoyu WEI, Qian HU, Zemao GU, Yanhe LI

“…Homeobox genes are ubiquitous in eukaryotic genomes and can be transcribed into a homeodomain of approximately 60 amino acids. Hox genes are currently the most studied class of homeobox genes. …”
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Teucrium polium induces apoptosis in peripheral blood lymphocytes isolated from human chronic lymphocytic leukemia by Zarić Milan, Živković-Zarić Radica, Mitrović Marina, Nikolić Ivana, Čanović Petar, Milosavljević Zoran, Jovanović Danijela, Zelen Ivanka

“…The activation of apoptosis is one of the main molecular mechanisms responsible for anti-cancer activities of most of the currently studied potential anti-cancer agents, including natural compounds. …”
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Recent advances in the biosynthesis and production optimization of gentamicin: A critical review by Feng Xu, Kaihao Hu, Ali Mohsin, Jie Wu, Lihuan Su, Yuan Wang, Rong Ben, Hao Gao, Xiwei Tian, Ju Chu

“…Subsequently, the article encapsulates a spectrum of strategies currently deployed to augment gentamicin yields. These strategies include mutation screening, molecular biological techniques, and optimization of the fermentation process. …”
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What ‘unexplored’ means: mapping regions with digitized natural history records to look for ‘biodiversity blindspots’ by Laymon Ball, Sheila Rodríguez-Machado, Diego Paredes-Burneo, Samantha Rutledge, David A. Boyd, David Vander Pluym, Spenser Babb-Biernacki, Austin S. Chipps, Rafet Ç. Öztürk, Yahya Terzi, Prosanta Chakrabarty

“…We also argue for increased scientific infrastructure so that more reference collections with vouchers can be kept in the countries of origin (particularly those countries lacking such infrastructure currently).…”
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THERAPEUTIC EYELIDS HYGIENE IN THE ALGORITHMS OF PREVENTION AND TREATMENT OF OCULAR SURFACE DISEASES. PART II by V. N. Trubilin, E. G. Poluninа, E. Y. Markova, V. V. Kurenkov, S, G. Kapkova

“…Ten or fifteen years ago, 2–3 tearsubstitudes were presented at the domestic market. Currently, there are doses of different forms of artificial tears, while there are hundreds of them on the western pharmaceutical market. …”
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In Vitro Efficacy of PEI-Derived Lipopolymers in Silencing of Toxic Proteins in a Neuronal Model of Huntington’s Disease by Luis C. Morales, Luv Modi, Saba Abbasi Dezfouli, Amarnath Praphakar Rajendran, Remant Kc, Vaibhavi Kadam, Simonetta Sipione, Hasan Uludağ

“…<b>Methods:</b> This study aims to investigate the efficacy of siRNA-containing nano-engineered lipopolymers in selectively silencing the <i>HTT</i> expression in a neuronal model expressing a chimeric protein formed by the human mutated exon 1 of the <i>HTT</i> gene, tagged with GFP. …”
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Development of an easy non‐destructive particle isolation protocol for quality control of red blood cell concentrates by Marine Ghodsi, Anne‐Sophie Cloos, Anaïs Lotens, Marine De Bueger, Patrick Van Der Smissen, Patrick Henriet, Nicolas Cellier, Christophe E. Pierreux, Tomé Najdovski, Donatienne Tyteca

“…Nevertheless, there is currently no standardized isolation protocol. In a previous publication, we developed a reproducible ultracentrifugation‐based protocol (20,000 × g protocol) that allows to classify red blood cell concentrates into three cohorts according to their vesiculation level. …”
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Digital platforms and news publishers: uneasy relationship by Petros Iosifidis

“…Whereas many of these activities were conducted through legacy news media, entities such as Google, Facebook, YouTube and Instagram currently dominate in most national contexts. The business models of digital platforms, their global nature and the pace that digital technologies and services evolve challenge existing regulatory frameworks concerning consumer protection, transparency, and power imbalances, especially in ensuring that substantial market power does not reduce competition in media and advertising services markets. …”
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White Rabbit FMC mezzanine as an interface for the new 10G WR-NIC to remote WR DAQ nodes by Bawaj Mateusz, Chiarusi Tommaso, Travaglini Riccardo

“…The White Rabbit protocol (WR), developed at CERN for the distribution of sub-nanosecond timing to thousands of nodes displaced over large geographic areas, is becoming increasingly reliable and is being utilized in various contexts, notably in modern multi-messenger astronomy experiments in progress such as KM3NeT, CTAO and ET. …”
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Innovation and Resignification: Social Entrepreneurship for Reincorporating Women into Peace Communities by Luz Elena Malagón-Castro, José Carlos Vázquez-Parra, Gloria Clemencia Valencia-González, Luis Guillermo Restrepo-Jaramillo

“…Educational strategies that foster Social Innovation, Entrepreneurship, and Complex Thinking are increasingly recognized as essential tools in this process, helping to rebuild social cohesion and empower local leadership. …”
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Who does technology serve? A critical analysis of sociocultural factors shaping opportunities, practices and barriers faced by a smallholders in south-western Colombia by Marcela Ramos, Natalia Triana, Stefan Burkart, Jhon Freddy Gutiérrez, Diana María Gutiérrez-Zapata, Alejandro Ruden, Lady Sepúlveda, Brian Barrett

“…Therefore, the study contends that, when understanding technology adoption, it is not only a question of what farmers do or do not do but of what they can be and do in increasingly demanding contexts.…”
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The involvement of the synaptic vesicle cycle in homocysteine induced neurotoxicity in vitro and in vivo by Meng Wang, Xiaoshan Liang, Keqing Jin, Yinyue Liu, Suhui Luo, Qiang Zhang, Xuan Wang, Zhiping Dong, Xumei zhang

“…However, there is currently a lack of comprehensive understanding regarding the molecular mechanisms underlying Hcy-induced neurotoxicity. …”
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Preparation, mechanical, and thermal properties of CrNbO4: A novel dual-functional scale to protect RHEAs from oxidation and thermal attack by Shuang Zhang, Jian Zhang, Xiaohui Wang, Huimin Xiang, Cheng Fang, Wei Xie, Yanchun Zhou

“…Interestingly, the room temperature thermal conductivity of CrNbO4 is 1.09 W·m−1·K−1 and decreases to 0.45 W·m−1·K−1 at 1473 K, which is lower than that of most of the currently well-known thermal insulation materials. …”
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