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2541
Assessment of the phenolic profile and biological activities of aqueous date seed extracts: A comparative analysis
Published 2024-12-01“…Date palm fruit (Phoenix dactylifera L.) is a well-known fruit that has become increasingly popular among consumers due to its pleasant flavor, nutrient-dense content, and nutraceutical characteristics. …”
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2542
CAR-T cells and TRUCKs that recognize an EBNA-3C-derived epitope presented on HLA-B*35 control Epstein-Barr virus-associated lymphoproliferation
Published 2020-10-01“…IL-12, secreted by TRUCKs on target contact, was further tested for its chemoattractive and activating potential towards monocytes and natural killer (NK) cells.Results After co-cultivation with EBV target cells, TÜ165 CAR-Ts and TRUCKs showed an increased activation marker expression (CD137, CD25) and release of proinflammatory cytokines (interferon-γ and tumor necrosis factor-α). …”
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2543
Climate variability off Africa's southern Cape over the past 260 000 years
Published 2025-07-01“…At the same time, this region preserves some of the most abundant Middle Stone Age (MSA) archaeological sites containing records of <i>Homo sapiens</i> behavioural and technological evolution. …”
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2544
Helminth Coinfections Modulate Disease Dynamics and Vaccination Success in the Era of Emerging Infectious Diseases
Published 2025-04-01“…Helminth infection can also negatively impact vaccine efficacy by suppressing B cell activity, reducing antibody levels, and decreasing vaccine effectiveness against infectious diseases. …”
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2545
Potential Herb-Drug Interactions Among Elderly Nursing Home Residents in Romania
Published 2025-01-01“…Evidence shows that herb-drug interactions (HDIs) are significant in clinical pharmacology. However, the current use of herbal supplements and the prevalence of HDIs among elderly patients in nursing homes is not known. …”
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2546
Optimal dietary vitamin E level facilitates ovarian development of female largemouth bass (Micropterus salmoides) broodstock
Published 2025-04-01“…The current study was designed to explore the effects of dietary vitamin E on the ovarian development and health of female largemouth bass (Micropterus salmoides). …”
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2547
The association between dietary fat quality and quantity and hospitalization duration in COVID-19 in Iranian patients: a cross-sectional study
Published 2025-04-01“…Additionally, there was a positive association between CSI levels and DH. Current findings indicate that the quality and balance of dietary fats may play a crucial role in modulating inflammatory responses and clinical outcomes.…”
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2548
Fexuprazan safeguards the esophagus from hydrochloric acid-induced damage by suppressing NLRP1/Caspase-1/GSDMD pyroptotic pathway
Published 2024-12-01“…Esomeprazole, a representative PPI, and three currently marketed P-CABs (vonoprazan, tegoprazan, and fexuprazan) were used for pretreatment. …”
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2549
Safety, Feasibility, and Tolerability of Ten Days of At-Home, Remotely Supervised tDCS During Gamified Attention Training in Children with Acquired Brain Injury: An Open-Label, Dos...
Published 2025-05-01“…When delivered daily, transcranial direct current stimulation (tDCS) may improve attention; however, access to daily in-clinic tDCS treatment can be limited by other commitments, including concurrent therapy, school commitments, and caregiver schedules. …”
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2550
Elevated levels of Letm1 drives mitochondrial dysfunction and cardiomyocyte stress-mediated apoptosis in cultured cardiomyocytes
Published 2025-08-01“…Electrophysiologically, Letm1 reduced L-type Ca2+ current density and significantly shortened action potential duration, leading to impaired contractility. …”
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2551
Artificial Intelligent Model to Enhance Thermal Conductivity of TiO<sub>2</sub>-Al<sub>2</sub>O<sub>3</sub>/Water-Ethylene Glycol-Based Hybrid Nanofluid for Automotive Radiator
Published 2024-01-01“…Vehicular cooling system is one of the priorities for the automobile industry, aiming to achieve sustainability and energy efficiency. Currently, coolants are being utilized in cooling systems that exhibit super heat transfer capabilities. …”
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2552
Vertical distribution of <sup>137</sup>Cs in soddy-podzolic sandy soil in grasslands and forests of the Bryansk region in 2015–2016
Published 2019-10-01“…In practical terms, it indicates that the depth of soil sampling equal to 20 cm is currently quite sufficient to estimate the dose rate of gamma radiation in the air in virgin grasslands and in forests.…”
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2553
Transmission network and phylogenetic analysis reveal older male-centered transmission of CRF01_AE and CRF07_BC in Guangxi, China
Published 2023-12-01“…In China, the number of newly reported HIV infections in older people is increasing rapidly. However, clear information on the impact of older people on HIV transmission is limited. …”
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2554
Synergistic Effects of Mannan Oligosaccharides and Onion Peels on In Vitro Batch Culture Fermentation of High Concentrate and Forage Diets
Published 2024-11-01“…Administration of MOS:2OP to the HC diet increased GP at 24 h of incubation, while the lowest GP was observed with the OP in the HF diet. …”
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2555
Multi-method evaluation of volatile flavor compounds in five kiwifruit varieties
Published 2025-07-01“…[Objective] Fruit wine, as a food of fruit processing, not only enhances the flavor diversity of kiwifruit but also increases its biological activity, leading to the production of kiwifruit wine with a unique flavor, combined fruit with wine aromas, and rich nutrition. …”
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2556
Microvesicles Derived from Human Embryonic Neural Stem Cells Inhibit the Apoptosis of HL-1 Cardiomyocytes by Promoting Autophagy and Regulating AKT and mTOR via Transporting HSP-70
Published 2019-01-01“…Additionally, hESC-NSC-derived MVs contained high levels of heat shock protein 70 (HSP-70), which can increase the level of HSP-70 in cells. …”
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2557
In vitro antitumor and immunomodulatory activities of 1,2,4-oxadiazole derivatives
Published 2025-03-01“…Exposure to melanoma murine supernatants also promotes M1 polarization. Supernatants containing traces of 1,2,4-oxadiazole derivative 2 (Supernatants B, C, and D) increased the percentage of M1 cells compared to Supernatant A, as well as elevated levels of nitrite, TNF-α, and IL-12. 1,2,4-oxadiazole derivative 2 combined with Supernatant A and 1,2,4-oxadiazole derivative 2 combined with LPS also resulted in higher M1 polarization, suggesting a synergistic effect on M1 polarization and TNF-α production. …”
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2558
PANCAKE: A Python-based Numerical Color–Magnitude Diagram Analysis Package
Published 2025-01-01“…The color–magnitude diagram (CMD) stands out as the most accurate tool currently available for inferring the star formation histories (SFHs) of nearby galaxies with stellar-resolved multiband data. …”
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2559
Dealing with Complexity – Knowledge, design, and management of the built environment
Published 2024-12-01“…How do we place knowledge and learning into a system to better understand the current era’s multidimensional, fundamental, and global issues in their irreducible complexity? …”
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2560
Comparative chromium adsorptive capacity of different low-cost materials using fixed bed column
Published 2025-07-01“…Abstract The accessibility of pure water is crucial for various human activities and is increasingly in demand due to the growing global population. …”
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