Interference in melanoma CD248 function reduces vascular mimicry and metastasis by Cheng-Hsiang Kuo, Ya-Fang Wu, Bi-Ing Chang, Chao-Kai Hsu, Chao-Han Lai, Hua-Lin Wu

“…Abstract Background Tumor vascular mimicry is an emerging issue that affects patient survival while having no treatment at the current moment. Despite several factors implicated in vascular mimicry, little is known about stromal factors that modulate tumor microenvironment and shape malignant transformation. …”
Get full text

Spatial transcriptomic characteristics of gastric cancer in young and the expression and role of TMEM176B in gastric cancer cells by Zhenhua Jiang, Yongfeng Wang, Chi Zhang, Shuangyin Han

“…Abstract Background Gastric cancer in young (GCY) is increasing in incidence with poor prognosis. Current screening and molecular methods are inadequate, necessitating new approaches to explore its pathogenesis. …”
Get full text

Assessment of synergy-assisted EMG-driven NMSK model for upper limb muscle activation prediction in cross-country sit-skiing double poling by Xue Chen, Zhongxue Yuan, Xianzhi Gao, Yanxin Zhang, Chenglin Liu, Bo Huo, Bo Huo

“…However, frequent shoulder joint movements significantly increase the incidence of shoulder joint disorders. …”
Get full text

Mitigating fatigue in long COVID patients with MYPplus: a clinical observation by Yu-Jin Choi, Jin-Seok Lee, Jin-Yong Joung, Seung-Ju Hwang, Young-Yil Kim, Chang-Gue Son

“…It is estimated that approximately 10% of individuals who contact COVID-19 develop Long COVID, with fatigue and brain fog being among the most commonly reported and debilitating symptoms. …”
Get full text

Beyond the brain: early autonomic dysfunction in Alzheimer’s disease by Carmen Nanclares, Inés Colmena, Alicia Muñoz-Montero, Andrés M. Baraibar, Ricardo de Pascual, Aneta Wojnicz, Ana Ruiz-Nuño, Antonio G. García, Adrián Gironda-Martínez, Luis Gandía

“…These changes were accompanied by diminished sodium (INa), calcium (ICa), and nicotinic (IACh) currents, compromising CC excitability. With age, a shift toward increased potassium (IK) currents and enhanced catecholamine secretion may reflect compensatory adaptations aimed at preserving output. …”
Get full text

What type of leadership is more effective for managing change during force majeure? Achieving organizational effectiveness during the pandemic by Nazia Habib, Shaheryar Naveed, Muhammad Mumtaz, Rabia Sultana, Shoaib Akhtar

“…Hence, it was important to identify effective leadership styles to successfully manage the transformational process during the period. Therefore, the current study aims to explore and compare the effectiveness of transformational and ethical leadership (EL) in terms of achieving organizational goals during COVID-19 in public and private sector organizations in Pakistan. …”
Get full text

Cost-effectiveness of atezolizumab plus bevacizumab versus sorafenib as first-line therapy in unresectable hepatocellular carcinoma in the US and Chinese setting: a modelling compa... by Lei Wang, Lulu Liu, Yiling Ding, Qilin Zhang, Yamin Shu

“…In scenario analyses, the atezolizumab plus bevacizumab treatment becomes favourable when the cost of atezolizumab decreases to 67.85% and 18.45% of its original price in the USA and China, respectively.Conclusions The atezolizumab plus bevacizumab is unlikely to be cost-effective compared with sorafenib for patients with unresectable HCC in the context of the USA and China. …”
Get full text

THE IMPACT OF THE USE OF BIOFUELS ON CO2 EMISSIONS AT THE LEVEL OF EUROPEAN COUNTRIES FROM THE PERSPECTIVE OF ABSOLUTE DECOUPLING by Valentina SIMION, Liviu MARCUTA, Maricel CAZACU, Nicolae MINEA, Camelia HODOAȘAN

“…Decoupling economic growth from CO2 emissions completely is still a key goal of sustainability programs. According to the current research, nations with faster energy transitions and advanced technologies typically see a sharper decoupling, meaning that real GDP growth is attained without a rise in greenhouse gas emissions. …”
Get full text

Adverse birth outcome research case definitions associated with maternal HIV and antiretroviral drug use in pregnancy: a scoping review by Kopano R. Dube, Shani T. de Beer, Kathleen M. Powis, Michael McCaul, Amy L. Slogrove

“…In conjunction with good reporting, variation in adverse birth outcome definitions can be decreased to facilitate comparability of studies as well as pooling of data for enhanced evidence synthesis.…”
Get full text

Application of urinary peptide-biomarkers in trauma patients as a predictive tool for prognostic assessment, treatment and intervention timing by Gökmen Aktas, Felix Keller, Justyna Siwy, Agnieszka Latosinska, Harald Mischak, Jorge Mayor, Jan Clausen, Michaela Wilhelmi, Vesta Brauckmann, Stephan Sehmisch, Tarek Omar Pacha

“…Preemptive personalized treatment aimed at preventing these events is a crucial objective of patient management; however, the currently available scoring systems provide only moderate guidance. …”
Get full text

Gastrocnemius activation deficits and running biomechanics after anterior cruciate ligament reconstruction: the missing link? by Florian Forelli, Florian Forelli, Florian Forelli, Ayrton Moiroux-Sahraoui, Ayrton Moiroux-Sahraoui, Jean Mazeas, Jean Mazeas, Anais Pengue Koyi, Mouna Labib, Adrien Cerrito

“…They also demonstrated altered running biomechanics, including longer ground contact time (0.29 vs. 0.26 s, p = 0.02, d = − 0.5), shorter stride length (1.32 vs. 1.41 m, p = 0.03, d = 0.9), reduced vertical stiffness (21.8 vs. 25.6 kN.m−1, p = 0.03, d = 0.5), and slightly increased step width (0.14 vs. 0.13 m, p = 0.05, d = 0.4). …”
Get full text

Evaluating the effect of vitamin D3 fortification on physicochemical and sensory properties of yogurt by Saneela Saleem, Zahra Khan, Imtiaz Hussain, Faran Khan, Fahad Al-Asmari, Faima Atta Khan, Alyan Ali Zafar, Muhammad Abdul Rahim, Zongo Eliasse, Mohamed Fawzy Ramadan

“…During the first week of storage, the viscosity of yogurt increased but later it started decreasing because of syneresis. …”
Get full text

Gender differences of neurometabolic and neuroendocrine alternations and its lateralization in adolescents with major depressive disorder by Xiaodong Song, Shuya Yan, Shunkai Lai, Yiliang Zhang, Ying Wang, Jiali He, Dong Huang, Jianzhao Zhang, Xiaodan Lu, Guanmao Chen, Pan Chen, Qilin Zhong, Rongxu Zhang, Yangyu Wu, Jie Yin, Shuming Zhong, Yanbin Jia

“…Abstract Background The clinical characteristics of major depressive disorder (MDD) in adolescents show notable gender-related differences, but the cause of these differences is still not understood. The current research concentrates on the changes in neurometabolism and neuroendocrine function, aiming to identify differences in endocrine function and brain metabolism between male and female adolescents with MDD. …”
Get full text

Improving mesophilic anaerobic digestion of compostable packaging through efficient and versatile thermo-alkaline pre-treatment by Gaël Huet, Julie Lamarque, Florian Monlau, Valentin Puchelle, Cecilia Sambusiti, Juliana Catalina Suarez Murcia, Sandra Domenek, Florian Pion, Emmanuelle Gastaldi

“…As a result, Biochemical Methane Potentials (BMP) were significantly increased with improvements ranging from 2 to 3 times for bags and 1.4 to 17 times for coffee capsules, even though they contained PBAT, PLA or PBS. …”
Get full text

Replacing fishmeal with an insect meal blend: Implications for intestinal microbiota in European seabass by Violeta Kalemi, Simona Rimoldi, Rafaela S. Costa, Ana Basto, Marta Monteiro, Genciana Terova, Luisa M.P. Valente

“…This research stands out by examining a combination of IMs rather than a single source, thereby addressing an underexplored area in the current literature. In a feeding trial that lasted 75 days, European seabass were fed three different diets: a commercial-like control diet and two experimental diets containing partial replacement of FM with IM (25 % and 50 %). …”
Get full text

Compost from the food waste for organic production of cabbage, cauliflower, and radish under sub-tropical conditions by Neha Kumari, Anit Sharma, Mamta Devi, Atif Zargar, Sunny Kumar, Umesh Thakur, Ajay Bhatia, Khushboo Badhan, Sunaina Chandel, Arpana Devi, Kriti Sharma, Shweta Kumari, Mussarat Choudhary, Arup Giri

“…Purpose In the current scenario, food wastage is a significant concern throughout the world. …”
Get full text

Recent Developments in the Physical Adsorption of Toxic Organic Vapours by Activated Carbons by Robert H. Bradley

“…Against this background, it is not surprising that there is currently great interest in active carbons with controllable properties and increased adsorption performance to meet these new challenges. …”
Get full text

Ozonation of 4-aminotoluene as a new method of synthesis of 4-aminobenzaldehyde – an intermediate for the production of anti-tuberculosis drugs by A. H. Halstian, A. S. Вushuiev, Ye. Yu. Vasylenko

“…Continuous control of the current ozone concentration and recording the results in the form of a kinetic curve was carried out when passing ozone-containing gas through the container of the spectrophotometer “SF-46 LOMO” at a certain wavelength of a monochromatic light source. …”
Get full text

New insights on physicochemical features and toxicological outcome provided from incineration of nanocomposites by Claire Longuet, Carine Chivas-Joly, Nora Lambeng, Valérie Forest, Lara Leclerc, Gwendoline Sarry, Jérémie Pourchez, José-Marie Lopez-Cuesta

“…A specific management of nanocomposites end-of-life should be implemented as recommended by the Organization for Economic Co-operation and Development (OECD) in order to limit nanoparticles dissemination by landfilling and particularly in incineration facilities where their presence is significantly increasing. The aim of our study was to expand the current knowledge of the partition of nanowaste, mainly in case of nanocomposites mixture, and the potential synergetic or antagonistic impact of potential hazardous nanowastes on the toxicological profile. …”
Get full text

Content of Selected Compounds in the Exhaust Gas of a Naturally Aspirated CI Engine Fueled with Diesel–Tire Pyrolysis Oil Blend by Leszek Chybowski, Marcin Szczepanek, Waldemar Kuczyński, Iwona Michalska-Pożoga, Tomasz Pusty, Piotr Brożek, Robert Pełech

“…The consumption of D90+RF10 increased by 56%, and CO₂ emissions were 21.7% higher at low loads. …”
Get full text