Neutrophil-to-Lymphocyte ratio as surrogate for JAK2V617F suppression and event-free survival in polycythemia vera by Tiziano Barbui, Arianna Ghirardi, Victoria Empson, Francesca Fenili, Giuseppe Gaetano Loscocco, Annalisa Condorelli, Alessandra Iurlo, Daniele Cattaneo, Elena Rossi, Valerio De Stefano, Paola Guglielmelli, Christoph Klade, Heinz Gisslinger, Alessandro Rambaldi, Joseph M. Scandura, Alessandro Maria Vannucchi

“…Abstract Chronic systemic inflammation is a key driver of polycythemia vera (PV) progression, but the immunomodulatory effects of current treatments remain poorly defined. The neutrophil-to-lymphocyte ratio (NLR) is an accessible biomarker of systemic inflammation proven in other contexts, but its role in monitoring PV disease activity has not been established. …”
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Nutritional management of pediatric nephrotic syndrome regarding oxidative stress and antioxidant balance by Elena Jechel, Alin Horatiu Nedelcu, Felicia Dragan, Vasile Valeriu Lupu, Iuliana Magdalena Starcea, Adriana Mocanu, Solange Tamara Rosu, Violeta Streanga, Ruxandra Russu, Ginel Baciu, Ciprian Danielescu, Delia Lidia Salaru, Ionela Daniela Morariu, Olga Cirstea, Emil Anton, Ancuta Lupu

“…The analysis focuses on the molecular mechanisms by which oxidative stress contributes to the progression of renal dysfunction, the role of oxidative biomarkers in disease monitoring, and the ability of antioxidants to reduce the need for immunosuppressants and corticosteroids, thus contributing to the decrease in associated morbidity. The translational perspectives of antioxidant therapy are also discussed, in the context of the urgent need for effective adjuvant strategies with a safety profile superior to conventional therapies. …”
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Evaluation of Total Electron Content Prediction Using Three Ionosphere‐Thermosphere Models by O. Verkhoglyadova, X. Meng, A. J. Mannucci, J.‐S. Shim, R. McGranaghan

“…The meanings of contingency table elements for the prediction performance are analyzed in the context of ionosphere modeling. Prediction success is between about 0.2 and 0.5 for weak ionospheric disturbances and decreases for strong disturbances. …”
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Reducing mine water contamination at the local drainage facility of a kimberlite mine by N. P. Ovchinnikov

“…As Russian kimberlite mines reach their design capacity, the interval between cleaning cycles of the local drainage system’s water collectors has significantly decreased. Currently, at kimberlite mines, the cleaning of silted water collectors is routinely carried out using all available load–haul–dump (LHD) machines operated by the mine’s Mechanical and Power Service. …”
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Resolution on the results of the first working meeting of the scientific advisory board «Actual problems of glycemic variability as a new criterion of glycemic control and safety o... by Mikhail B. Antsiferov, Gagik R. Galstyan, Alexey V. Zilov, Alexander Y. Mayorov, Tatyana N. Markova, Nikolay A. Demidov, Olga M. Koteshkova, Dmitry N. Laptev, Alisa V. Vitebskaya

“…The aims of the working meeting were to conduct a comprehensive data analysis of the relationship between GV and hypoglycaemia; to gather and analyse published data and the experience of decrease in GV and improved outcomes of diabetes against the background of different types of insulin therapy; to compare existing methods of glycaemia monitoring and GV assessment and examine their validity and availability in real practice in the context of limited budget and to analyse the informativeness and clinical and prognostic significance of various parameters of GV assessment and to determine their reasonable ‘minimum’ for a comprehensive assessment of GV as a criterion for evaluating the effectiveness of DM treatment and the predictors of negative diabetes outcomes. …”
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Latest trends on interplay of autophagy, adipose tissue, and gut microbiota in obesity-related metabolic disorders by Claudette Butoyi, Muhammad Asad Iqbal, Isaac Duah Boateng

“…Purpose of review: This review aims to synthesize current research on the intricate relationships among visceral obesity (VO), autophagy (Atg), gut microbiota, and adipose tissue dysfunction, all of which contribute significantly to insulin resistance (IR) and associated metabolic disorders. …”
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A comprehensive review of the genetic control of cooking time in dry beans (Phaseolus vulgaris L.) by Hannah R. Jeffery, Marcelo Efrén Murillo‐Quesada, Luis Barboza‐Barquero, Karen Cichy

“…The current evidence suggests that cooking time is increased by genetic factors that decrease the amount of soluble compounds in the cotyledons, including but not limited to 1) genes that increase the abundance of calcium‐binding storage proteins and/or de‐methylesterfied pectins paired with high inter‐ or intra‐cellular calcium levels (higher calcium levels can be caused by reduced levels of phytate) and 2) genes that increase insoluble condensed tannin/lignin content in the cotyledon cell walls. …”
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Azov-type spits: long-term monitoring of morphodynamics and vegetation in response to changing environment by Oksana Tyshchenko, Volodymyr Tyshchenko, Svitlana Boychenko, Andrii Tarieiev, Vasyl Tkachenko

“…The study provides a complex evaluation of the current anthropogenic impacts on the spits and their vegetation.…”
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Average nutrient and chlorophyll distributions in the western Mediterranean: RADMED project by María del Carmen García-Martínez, Manuel Vargas-Yáñez, Francina Moya, Rocío Santiago, María Muñoz, Andreas Reul, Teodoro Ramírez, Rosa Balbín

“…The present work analyses nutrient, chlorophyll and oxygen time series from 2007 to 2015 in some cases and from 1992 in other cases. The current analyses show a clear trophic gradient in the RADMED area. …”
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Optimal Decision-Making in a Green Supply Chain Duopoly: A Comparative Analysis of Subsidy Strategies with Data-Driven Marketing by Yao Yao, Shaoqing Geng, Jianhui Chen, Feng Shen, Huajun Tang

“…In the current context of severe environmental challenges and climate change, the low-carbon green development model has become an international consensus. …”
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INTERNATIONAL EXPERIENCE AND TRENDS OF INNOVATIVE DEVELOPMENT OF ARCTIC TERRITORIES by M. Dudin, N. Ivashchenko

“…As a consequence of that, it is expected that in the XXI century the Arctic region will be the focus of attention as an official Arctic 45, and a number of states whose territory is quite removed from it; For Russia, given the current, acute political conditions (sanctions, confrontation with the West, Ukrainian crisis and war in the Middle East) development of Arctic territories, some moved away, moved on tomorrow and the day after tomorrow on the agenda. …”
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Administrator Turnover: The Roles of District Support, Safety, Anxiety, and Violence from Students by Andrew H. Perry, Linda A. Reddy, Andrew Martinez, Susan D. McMahon, Eric M. Anderman, Ron A. Astor, Dorothy L. Espelage, Frank C. Worrell, Taylor Swenski, Kailyn Bare, Christopher M. Dudek, Jared Hunt, Adriana I. Martinez Calvit, Hyun Ji Lee, Xi Liu

“…Findings highlight the importance of district support of administrators for reducing mental health concerns and transfer/quit intentions in the context of student violence against school administrators. …”
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Continuing the continuous harvests of food production: from the perspective of the interrelationships among cultivated land quantity, quality, and grain yield by Peng Cheng, Yang Zhang, Ke Liu, Xuesong Kong, Shiman Wu, Huafei Yan, Ping Jiang

“…This successive increase in food production in the context of decreasing acreage and ecological deterioration of CL depend mainly on the amount of chemical fertilizer usage, the total power of agricultural machinery and rural electricity consumption. …”
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Cognitive Outcomes and Functional Performance for Patients After Open Heart Surgery by Mona A. Hassenien, Sahar Y Mohammad, Dalia A. Ameen

“… Context: Open heart surgery is a lifesaving procedure for patients who need coronary artery bypass graft (CABG) and heart valve replacement or repair (HVR). …”
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Comparison and theoretical conceptualization analysis of statistical methods used to develop heat vulnerability indices in urban areas by Thomas Lagelouze, Julia Hidalgo, Mitia Aranda, Guillaume Dumas

“… In view of the impact of extreme temperatures on physical and psychological health, particularly in urban areas, several studies have focused on assessing social vulnerability using quantitative indexing approaches with the aim of creating a heat vulnerability index (HVI). In this context, this study employs three statistical methodologies frequently used to construct HVIs on the territory of the Toulouse Métropole, France, at the census block (IRIS) scale to assess the efficiency of this type of approach for evaluating social vulnerability in urban environments considering the current theoretical conceptualization. …”
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Examining the longitudinal associations between activity limitations, instrumental supports and social participation in osteoarthritis: A CLSA population-based study. by Anthony V Perruccio, Calvin Yip, J Denise Power, Mayilee Canizares, Elizabeth M Badley

“…<h4>Objective</h4>In osteoarthritis (OA) research, disability is largely studied within the context of activities of daily living. Broader consequences for social participation are often overlooked. …”
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Introducing the non-invasive prenatal test for trisomy 21 in Belgium: a cost-consequences analysis by Mattias Neyt, Frank Hulstaert, Wilfried Gyselaers

“…The objective is to estimate the consequences of introducing NIPT for the detection of T21.Methods A cost-consequences analysis was performed presenting the impact on benefits, harms and costs. Context-specific real-world information was available to set up a model reflecting the current screening situation in Belgium. …”
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INTERACTION BETWEEN DENTO-MAXILLOFACIAL ANOMALIES AND GENERAL-SOMATIC HUMAN CONDITION (LITERATURE REVIEW) by L.V. Smaglyuk, H.V. Voronkova, A.Ye. Karasiunok, A.V. Liakhovska, V.I. Smaglyuk

“…Over the last decade, there has been a clear trend towards an increase in the prevalence of malocclusion, which reaches 80% according to current scientific literature and sometimes it exceeds this percentage. …”
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An Agent-Based Simulation and Optimization Approach for Sustainable Urban Logistics: A Case Study in Lisbon by Renan Paula Ramos Moreno, Rui Borges Lopes, Ana Luísa Ramos, José Vasconcelos Ferreira, Diogo Correia, Igor Eduardo Santos de Melo

“…This study examines the PDP-TW in an urban logistics context using an integrated approach that combines an agent-based simulation model and an optimization model. …”
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Cost-utility of aripiprazole once-monthly versus paliperidone palmitate once-monthly injectable for schizophrenia in China. by Yiping An, Gang Fang, Zhipeng Pi, Yumeng Zhang, Wei Li, Jinxi Ding

“…A cost-effectiveness threshold (CET) of 0.51 times China's 2023 gross domestic product (GDP) (US$ 6,394.536) was used to judge the economics of intervention.<h4>Results</h4>The current price of AOM in China is relatively high (US$418.140). …”
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